Difference between revisions of "BrainAreaFAM"
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| [[BrainAreaLAC|LAC]] || [[BrainRegionFAM_FD_LHB_LT|FAM.FD.LHB.LT]] || [[BrainRegionLAC_FD_HT_LTN|LAC.FD.HT.LTN]] || Lateral Hypothalamic Nucleus || nucleus-nucleus || [http://journal.frontiersin.org/article/10.3389/fnhum.2013.00826/full Regulation of the rapid eye movement (REM) sleep by habenular projection (LHT -> LHbL)] | | [[BrainAreaLAC|LAC]] || [[BrainRegionFAM_FD_LHB_LT|FAM.FD.LHB.LT]] || [[BrainRegionLAC_FD_HT_LTN|LAC.FD.HT.LTN]] || Lateral Hypothalamic Nucleus || nucleus-nucleus || [http://journal.frontiersin.org/article/10.3389/fnhum.2013.00826/full Regulation of the rapid eye movement (REM) sleep by habenular projection (LHT -> LHbL)] | ||
|- | |- | ||
| − | | || || [[ | + | | || || [[BrainRegionLAC_FD_HT_VLPO|LAC.FD.HT.VLPO]] || Ventrolateral Preoptic Nucleus || nucleus-nucleus || [http://www.scholarpedia.org/article/Habenula Habenula Connections (LPO -> LHb, abstract)] |
|- | |- | ||
| || [[BrainRegionFAM_FD_LHB_MED|FAM.FD.LHB.MED]] || [[BrainRegionLAC_FD_HT_LTN|LAC.FD.HT.LTN]] || Lateral Hypothalamic Nucleus || nucleus-nucleus || [http://www.nature.com/neuro/journal/v17/n9/fig_tab/nn.3779_F2.html Both LHb and MHb control the dopaminergic and serotonergic systems (LHA -> LHbM)] | | || [[BrainRegionFAM_FD_LHB_MED|FAM.FD.LHB.MED]] || [[BrainRegionLAC_FD_HT_LTN|LAC.FD.HT.LTN]] || Lateral Hypothalamic Nucleus || nucleus-nucleus || [http://www.nature.com/neuro/journal/v17/n9/fig_tab/nn.3779_F2.html Both LHb and MHb control the dopaminergic and serotonergic systems (LHA -> LHbM)] | ||
|- | |- | ||
| − | | || || [[ | + | | || || [[BrainRegionLAC_FD_HT_VLPO|LAC.FD.HT.VLPO]] || Ventrolateral Preoptic Nucleus || nucleus-nucleus || [http://www.scholarpedia.org/article/Habenula Habenula Connections (LPO -> LHb, abstract)] |
|- | |- | ||
| [[BrainAreaLMC|LMC]] || [[BrainRegionFAM_FD_LHB_LT|FAM.FD.LHB.LT]] || [[BrainRegionLMC_HT_LC|LMC.HT.LC]] || Locus Coeruleus || nucleus-nucleus-NE || [http://www.nature.com/nrn/journal/v11/n6/fig_tab/nrn2849_F7.html Contribution of nAChR subunits to nicotine withdrawal symptoms (LC -> LHB, abstract)] | | [[BrainAreaLMC|LMC]] || [[BrainRegionFAM_FD_LHB_LT|FAM.FD.LHB.LT]] || [[BrainRegionLMC_HT_LC|LMC.HT.LC]] || Locus Coeruleus || nucleus-nucleus-NE || [http://www.nature.com/nrn/journal/v11/n6/fig_tab/nrn2849_F7.html Contribution of nAChR subunits to nicotine withdrawal symptoms (LC -> LHB, abstract)] | ||
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| || || [[BrainRegionFMM_NC_PH_LEC|FMM.NC.PH.LEC]] || Lateral Entorhinal Cortex || neocortex-nucleus || [http://www.sciencedirect.com/science/article/pii/S030100820900183X Simplified model of hippocampal formation anatomy (EC -> Amyg, abstract)] | | || || [[BrainRegionFMM_NC_PH_LEC|FMM.NC.PH.LEC]] || Lateral Entorhinal Cortex || neocortex-nucleus || [http://www.sciencedirect.com/science/article/pii/S030100820900183X Simplified model of hippocampal formation anatomy (EC -> Amyg, abstract)] | ||
|- | |- | ||
| − | | [[BrainAreaLAC|LAC]] || [[BrainRegionFAM_FD_TH_PT|FAM.FD.TH.PT]] || [[ | + | | [[BrainAreaLAC|LAC]] || [[BrainRegionFAM_FD_TH_PT|FAM.FD.TH.PT]] || [[BrainRegionLAC_FD_HT_MPO|LAC.FD.HT.MPO]] || Median Preoptic Nucleus || nucleus-nucleus || (unknown reference) |
|- | |- | ||
| [[BrainAreaLMC|LMC]] || [[BrainRegionFAM_FT_AM_BM|FAM.FT.AM.BM]] || [[BrainRegionLMC_FT_NBM|LMC.FT.NBM]] || Basal Nucleus of Meynert || nucleus-nucleus-ACh || (unknown reference) | | [[BrainAreaLMC|LMC]] || [[BrainRegionFAM_FT_AM_BM|FAM.FT.AM.BM]] || [[BrainRegionLMC_FT_NBM|LMC.FT.NBM]] || Basal Nucleus of Meynert || nucleus-nucleus-ACh || (unknown reference) | ||
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| || [[BrainRegionFAM_FT_SEP_BAC|FAM.FT.SEP.BAC]] || [[BrainRegionFMM_FT_HF_SUBP|FMM.FT.HF.SUBP]] || Proximal Subiculum || nucleus-allocortex || [http://www.nature.com/nrn/journal/v5/n1/fig_tab/nrn1299_F4.html Medial mammillary nucleus and theta rhythm (SEP -> HF, abstract)] | | || [[BrainRegionFAM_FT_SEP_BAC|FAM.FT.SEP.BAC]] || [[BrainRegionFMM_FT_HF_SUBP|FMM.FT.HF.SUBP]] || Proximal Subiculum || nucleus-allocortex || [http://www.nature.com/nrn/journal/v5/n1/fig_tab/nrn1299_F4.html Medial mammillary nucleus and theta rhythm (SEP -> HF, abstract)] | ||
|- | |- | ||
| − | | [[BrainAreaLAC|LAC]] || [[BrainRegionFAM_FT_AM_MEA|FAM.FT.AM.MEA]] || [[ | + | | [[BrainAreaLAC|LAC]] || [[BrainRegionFAM_FT_AM_MEA|FAM.FT.AM.MEA]] || [[BrainRegionLAC_FD_HT_VLPO|LAC.FD.HT.VLPO]] || Ventrolateral Preoptic Nucleus || nucleus-nucleus || [http://www.pnas.org/content/107/40/17071/F1.expansion.html Role for serotonin in moral behavior (AMY -> HYP, abstract)] |
|- | |- | ||
| − | | || [[BrainRegionFAM_FT_AM_MPD|FAM.FT.AM.MPD]] || [[ | + | | || [[BrainRegionFAM_FT_AM_MPD|FAM.FT.AM.MPD]] || [[BrainRegionLAC_FD_HT_MPO|LAC.FD.HT.MPO]] || Median Preoptic Nucleus || nucleus-nucleus-gaba || [http://www.pnas.org/content/107/40/17071/F1.expansion.html Role for serotonin in moral behavior (AMY -> HYP, abstract)] |
|- | |- | ||
| || || [[BrainRegionLAC_FD_HT_PV|LAC.FD.HT.PV]] || Paraventricular Nucleus || nucleus-nucleus-gaba || [http://neuropolitics.org/defaultmay10.asp Amygdalar disruption of prefrontal cortex (AM -> HT.PV, abstract)] | | || || [[BrainRegionLAC_FD_HT_PV|LAC.FD.HT.PV]] || Paraventricular Nucleus || nucleus-nucleus-gaba || [http://neuropolitics.org/defaultmay10.asp Amygdalar disruption of prefrontal cortex (AM -> HT.PV, abstract)] | ||
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| [[BrainAreaFAM|FAM]] || [[BrainRegionFAM_FT_SEP_LT|FAM.FT.SEP.LT]] || [[BrainRegionFAM_FD_LHB_MED|FAM.FD.LHB.MED]] || Lateral Habenula Medial Part || nucleus-nucleus-gaba || [http://www.nature.com/neuro/journal/v17/n9/fig_tab/nn.3779_F2.html Both LHb and MHb control the dopaminergic and serotonergic systems (LS -> LHbM)] | | [[BrainAreaFAM|FAM]] || [[BrainRegionFAM_FT_SEP_LT|FAM.FT.SEP.LT]] || [[BrainRegionFAM_FD_LHB_MED|FAM.FD.LHB.MED]] || Lateral Habenula Medial Part || nucleus-nucleus-gaba || [http://www.nature.com/neuro/journal/v17/n9/fig_tab/nn.3779_F2.html Both LHb and MHb control the dopaminergic and serotonergic systems (LS -> LHbM)] | ||
|- | |- | ||
| − | | [[BrainAreaLAC|LAC]] || [[BrainRegionFAM_FT_SEP_LT|FAM.FT.SEP.LT]] || [[ | + | | [[BrainAreaLAC|LAC]] || [[BrainRegionFAM_FT_SEP_LT|FAM.FT.SEP.LT]] || [[BrainRegionLAC_FD_HT_VLPO|LAC.FD.HT.VLPO]] || Ventrolateral Preoptic Nucleus || nucleus-nucleus-gaba || [http://www.thebrainlabs.com Cingulate Gyrus (SEP -> HT, abstract)] |
|- | |- | ||
| [[BrainAreaLPC|LPC]] || [[BrainRegionFAM_FT_SEP_LT|FAM.FT.SEP.LT]] || [[BrainRegionLPC_FD_TH_PV|LPC.FD.TH.PV]] || Paraventricular Nucleus of Thalamus || nucleus-nucleus-gaba || (unknown reference) | | [[BrainAreaLPC|LPC]] || [[BrainRegionFAM_FT_SEP_LT|FAM.FT.SEP.LT]] || [[BrainRegionLPC_FD_TH_PV|LPC.FD.TH.PV]] || Paraventricular Nucleus of Thalamus || nucleus-nucleus-gaba || (unknown reference) | ||
Revision as of 09:50, 10 September 2015
Forebrain Affective Motivations Area
Home -> BiologicalLifeResearch -> BrainAreaFAM
Contents
- 1 Local Circuits
- 1.1 Acquisition of Avoidance Responses
- 1.2 Conscious Emotions Control
- 1.3 Conditional Context Sensory Data and Memory Attention
- 1.4 Express Flight Emotions
- 1.5 Express Fight Emotions
- 1.6 Solving Fight-Flight Dilemma
- 1.7 Memory Formation Affective Focus
- 1.8 Reward Emotions Control
- 1.9 Fast Unconditional Sensory Data and Association Memory
- 2 Thirdparty Circuits
- 3 References
Local Circuits
(generated)
| ID | Name | Regions |
| FAMXAA | Acquisition of Avoidance Responses | FAM.FD.LHB.LT, FAM.FD.LHB.MED |
| FAMXCEC | Conscious Emotions Control | FAM.FT.AM.BP, FAM.FT.AM.ITC, FAM.FT.SEP.SF, FAM.FT.SEP.TR |
| FAMXCS | Conditional Context Sensory Data and Memory Attention | FAM.FD.TH.PT, FAM.FT.AM.AB, FAM.FT.AM.BM, FAM.FT.AM.COA, FAM.FT.AM.LADL |
| FAMXEFL | Express Flight Emotions | FAM.FT.AM.MEA, FAM.FT.AM.MPD, FAM.FT.AM.MPV, FAM.FT.BNST, FAM.FT.IPAC.MED, FAM.FT.SEP.BAC |
| FAMXEFT | Express Fight Emotions | FAM.FT.AM.CEM, FAM.FT.SEP.SH |
| FAMXFFD | Solving Fight-Flight Dilemma | FAM.FT.SEP.LT |
| FAMXMF | Memory Formation Affective Focus | FAM.FT.SEP.DBB, FAM.FT.SEP.MED |
| FAMXREC | Reward Emotions Control | FAM.FD.MHB, FAM.FT.EPF, FAM.HT.TG.NI |
| FAMXUS | Fast Unconditional Sensory Data and Association Memory | FAM.FT.AM.CEC, FAM.FT.AM.CEL, FAM.FT.AM.COP, FAM.FT.AM.LAVL, FAM.FT.AM.LAVM |
Acquisition of Avoidance Responses
| Component ID | Component Name | Type | Service | Function | Comments |
| FAM.FD.LHB.LT | Lateral Habenula Lateral Part | nucleus | FAU | Encoding negative feedback, direct, Pallidal | |
| FAM.FD.LHB.MED | Lateral Habenula Medial Part | nucleus | FAU | Encoding negative feedback, direct, Septal |
Internal Region Connections:
- no connections
External Inbound Region Connections:
External Outbound Region Connections:
Conscious Emotions Control
| Component ID | Component Name | Type | Service | Function | Comments |
| FAM.FT.AM.BP | Parvicellular Basal Amygdaloid Nucleus | nucleus | FAU | enhance explicit memories in hippocampus about emotional situations | |
| FAM.FT.AM.ITC | Intercalated Amygdaloid Nuclei | nucleus | FAU | inhibit excessive emotional behavior | inhibitory |
| FAM.FT.SEP.SF | Septofimbrial Nucleus | nucleus | FAU | afferent to medial habenula, primary input to indirect encoding negative feedback | |
| FAM.FT.SEP.TR | Triangular Septal Nucleus | nucleus | FAU | afferent to medial habenula, interpeduncular nucleus |
Internal Region Connections:
- no connections
External Inbound Region Connections:
| Source Area | Local Region | Source Region | Source Name | Type | Reference |
| Cortical | |||||
| NDM | FAM.FT.AM.BP | NDM.NC.AL.DACG | Dorsal Anterior Cingulate Area | neocortex-nucleus | Role for serotonin in moral behavior (ACG -> AMY, abstract) |
| NDM.NC.AL.FPC | Lateral Frontopolar Cortex | neocortex-nucleus | Amygdala and its network (MPFC -> BLN, abstract) | ||
| NDM.NC.AL.VACG | Ventral Anterior Cingulate Area | neocortex-nucleus | Role for serotonin in moral behavior (ACG -> AMY, abstract) | ||
| FAM.FT.AM.ITC | NDM.NC.AL.DMPFC | Dorsomedial Prefrontal Cortex | neocortex-nucleus | (unknown reference) | |
| NDM.NC.AL.VMPFC | Ventromedial Prefrontal Cortex | neocortex-nucleus | (unknown reference) | ||
| Subcortical | |||||
| FAM | FAM.FT.AM.BP | FAM.FT.AM.LADL | Dorsolateral Amygdaloid Nucleus | nucleus-nucleus | Amygdala and its network (LA -> BLN, abstract) |
| FAM.FT.AM.LAVL | Ventrolateral Amygdaloid Nucleus | nucleus-nucleus | Amygdala and its network (LA -> BLN, abstract) | ||
| FAM.FT.AM.ITC | FAM.FT.AM.BM | Magnocellular Basal Amygdaloid Nucleus | nucleus-nucleus | (unknown reference) | |
| FAM.FT.AM.LADL | Dorsolateral Amygdaloid Nucleus | nucleus-nucleus | (unknown reference) | ||
| FAM.FT.SEP.SF | FAM.HT.TG.NI | Incertus Nucleus | nucleus-nucleus-gaba | (unknown reference) | |
| FAM.FT.SEP.TR | FAM.HT.TG.NI | Incertus Nucleus | nucleus-nucleus-gaba | (unknown reference) | |
| FMM | FAM.FT.SEP.SF | FMM.FT.HC.CA3D | Distal CA3 of Hippocampus | allocortex-nucleus | Connectivity map of the habenula (Hippo -> Septum, abstract) |
| FAM.FT.SEP.TR | FMM.FT.HF.SUBD | Distal Subiculum | allocortex-nucleus | Principal Connections of Hippocampus (HC -> SEP, abstract) |
External Outbound Region Connections:
Conditional Context Sensory Data and Memory Attention
| Component ID | Component Name | Type | Service | Function | Comments |
| FAM.FD.TH.PT | Paratenial Nucleus of Thalamus | nucleus | FAU | Gateway for multimodal information to limbic system used in selecting appropriate responses |
Projects to BNST, AM, OMPFC, ET; Direct behavior toward a particular outcome over a range of outcomes |
| FAM.FT.AM.AB | Accessory Basal Amygdaloid Nucleus | nucleus | FAU | enhance assotiative memory formation | proections to matrix of core of NACC |
| FAM.FT.AM.BM | Magnocellular Basal Amygdaloid Nucleus | nucleus | FAU | enhance emotional memories memories in medial prefrontal cortex | |
| FAM.FT.AM.COA | Anterior Cortical Amygdaloid Nucleus | nucleus | FAU | olfactory processing - conditional contextual signaling | |
| FAM.FT.AM.LADL | Dorsolateral Amygdaloid Nucleus | nucleus | FAU | conditional stimulus input - high-aggregated visual, auditory and somatic, patterns of perception |
LA2 |
Internal Region Connections:
| Source Region | Target Region | Type | Reference |
| FAM.FT.AM.COA | FAM.FT.AM.AB | nucleus-nucleus | (unknown reference) |
| FAM.FT.AM.LADL | FAM.FT.AM.AB | nucleus-nucleus | Summary of the main extra-amygdaloid and intra-amygdaloid connections in the rat (L -> AB, abstract) |
External Inbound Region Connections:
| Source Area | Local Region | Source Region | Source Name | Type | Reference |
| Cortical | |||||
| NCP | FAM.FT.AM.BM | NCP.NC.INS.PIC | Posterior Insular Cortex | neocortex-nucleus | (unknown reference) |
| FAM.FT.AM.LADL | NCP.NC.INS.PPC | Peripaleocortical Claustral | neocortex-nucleus | (unknown reference) | |
| NDM | FAM.FT.AM.BM | NDM.NC.AL.FPC | Lateral Frontopolar Cortex | neocortex-nucleus | Bowels control brain: gut hormones and obesity (OFC -> AMY, abstract) |
| FAM.FT.AM.LADL | NDM.NC.AL.VMPFC | Ventromedial Prefrontal Cortex | neocortex-nucleus | (unknown reference) | |
| NSA | FAM.FT.AM.LADL | NSA.FD.TH.MGB | Medial Geniculate Body | nucleus-nucleus | Amygdalar disruption of prefrontal cortex (TH -> AM, abstract) |
| NSA.NC.IT.TE | Inferotemporal Cortex | neocortex-nucleus | Amygdala and its network (ITC -> LA, abstract) | ||
| Subcortical | |||||
| FAM | FAM.FT.AM.AB | FAM.FT.AM.LAVM | Ventromedial Amygdaloid Nucleus | nucleus-nucleus | Summary of the main extra-amygdaloid and intra-amygdaloid connections in the rat (L -> AB, abstract) |
| FAM.FT.AM.BM | FAM.FT.AM.BP | Parvicellular Basal Amygdaloid Nucleus | nucleus-nucleus | (unknown reference) | |
| FAM.FT.AM.LADL | FAM.FT.IPAC.MED | Medial Interstitial Anterior Commissural Nucleus | nucleus-nucleus | (unknown reference) | |
| FEC | FAM.FD.TH.PT | FEC.FT.VP.VM | Ventral Pallidum Ventromedial | nucleus-nucleus-gaba | Saccadic Vision (BG -> Thalamus, abstract) |
| FMM | FAM.FT.AM.AB | FMM.FT.HF.SUBD | Distal Subiculum | allocortex-nucleus | Simplified model of hippocampal formation anatomy (SUB -> Amyg, abstract) |
| FMM.FT.HF.SUBP | Proximal Subiculum | allocortex-nucleus | Simplified model of hippocampal formation anatomy (SUB -> Amyg, abstract) | ||
| FMM.NC.PH.LEC | Lateral Entorhinal Cortex | neocortex-nucleus | Simplified model of hippocampal formation anatomy (EC -> Amyg, abstract) | ||
| LAC | FAM.FD.TH.PT | LAC.FD.HT.MPO | Median Preoptic Nucleus | nucleus-nucleus | (unknown reference) |
| LMC | FAM.FT.AM.BM | LMC.FT.NBM | Basal Nucleus of Meynert | nucleus-nucleus-ACh | (unknown reference) |
| LPC | FAM.FT.AM.COA | LPC.FT.MOB | Main Olfactory Bulb | nucleus-nucleus | (unknown reference) |
External Outbound Region Connections:
Express Flight Emotions
| Component ID | Component Name | Type | Service | Function | Comments |
| FAM.FT.AM.MEA | Medial Anterior Amygdaloid Nucleus | nucleus | FAU | olfactory processing | |
| FAM.FT.AM.MPD | Medial Posterior Dorsal Amygdaloid Nucleus | nucleus | FAU | reproductive behavior | MePD -> HT-MPN |
| FAM.FT.AM.MPV | Medial Posterior Ventral Amygdaloid Nucleus | nucleus | FAU | defensive behavior | MePV -> LAC.FD.HT.VM (reproductive+defensive), LAC.FD.HT.AH (defensive) |
| FAM.FT.BNST | Bed Nucleus of Stria Terminalis | nucleus | FAU | Mediate slow longer-lasting responses that accompany sustained threats | Major output from AM to HT, part of extended amygdala; medial part continues to medial AM, central part continues to central AM |
| FAM.FT.IPAC.MED | Medial Interstitial Anterior Commissural Nucleus | nucleus | FAU | Sharp, acute pain sensation | reciprocate its afferent connections, similar to medial part of central amygdaloid nucleus; projections to AM-Ce/BNST components, PB, and SOL originate chiefly from medial division; strong ACh projections from caudal IPACm to AM-BL-posterior and amygdalopiriform transition area |
| FAM.FT.SEP.BAC | Bed Nucleus of Anterior Commissure | nucleus | FAU | projection to contralateral HC |
Internal Region Connections:
| Source Region | Target Region | Type | Reference |
| FAM.FT.AM.MEA | FAM.FT.AM.MPD | nucleus-nucleus | (unknown reference) |
| FAM.FT.AM.MPV | nucleus-nucleus | (unknown reference) | |
| FAM.FT.BNST | nucleus-nucleus | (unknown reference) | |
| FAM.FT.IPAC.MED | nucleus-nucleus | (unknown reference) | |
| FAM.FT.AM.MPV | FAM.FT.BNST | nucleus-nucleus-gaba | (unknown reference) |
| FAM.FT.BNST | FAM.FT.IPAC.MED | nucleus-nucleus | (unknown reference) |
| FAM.FT.SEP.BAC | nucleus-nucleus | (unknown reference) |
External Inbound Region Connections:
| Source Area | Local Region | Source Region | Source Name | Type | Reference |
| Cortical | |||||
| NCP | FAM.FT.BNST | NCP.NC.AL.SGCG | Subgenual Cingulate Cortex | neocortex-nucleus | (unknown reference) |
| NSA | FAM.FT.IPAC.MED | NSA.NC.PH.PIR | Piriform Cortex | neocortex-nucleus | (unknown reference) |
| Subcortical | |||||
| FAM | FAM.FT.AM.MEA | FAM.FT.AM.COP | Posterior Cortical Amygdaloid Nucleus | nucleus-nucleus | (unknown reference) |
| FAM.FT.AM.MPD | FAM.FT.AM.AB | Accessory Basal Amygdaloid Nucleus | nucleus-nucleus | Summary of the main extra-amygdaloid and intra-amygdaloid connections in the rat (AB -> M, abstract) | |
| FAM.FT.AM.MPV | FAM.FT.AM.LAVM | Ventromedial Amygdaloid Nucleus | nucleus-nucleus | Summary of the main extra-amygdaloid and intra-amygdaloid connections in the rat (L -> M, abstract) | |
| FAM.FT.BNST | FAM.FD.TH.PT | Paratenial Nucleus of Thalamus | nucleus-nucleus | (unknown reference) | |
| FAM.FT.AM.CEL | Central Amygdaloid Nucleus, lateral subdivision | nucleus-nucleus | (unknown reference) | ||
| LAC | FAM.FT.BNST | LAC.FD.HT.VM | Ventromedial Hypothalamic Nucleus | nucleus-nucleus | (unknown reference) |
| LPC | FAM.FT.AM.MEA | LPC.FT.AOB | Accessory Olfactory Bulb | nucleus-nucleus | (unknown reference) |
| FAM.FT.BNST | LPC.FD.TH.PV | Paraventricular Nucleus of Thalamus | nucleus-nucleus | (unknown reference) |
External Outbound Region Connections:
| Target Area | Local Region | Target Region | Target Name | Type | Reference |
| Subcortical | |||||
| FAM | FAM.FT.AM.MEA | FAM.FT.AM.CEM | Medial Central Amygdaloid Nucleus | nucleus-nucleus | Body alarm system (MED -> CE, abstract) |
| FAM.FT.AM.MPV | FAM.FT.SEP.LT | Lateral Septal Nucleus | nucleus-nucleus-gaba | (unknown reference) | |
| FAM.FT.IPAC.MED | FAM.FT.AM.LADL | Dorsolateral Amygdaloid Nucleus | nucleus-nucleus | (unknown reference) | |
| FAM.FT.SEP.BAC | FAM.FD.MHB | Medial Habenula | nucleus-nucleus | Connectivity map of the habenula (Septum -> M, abstract) | |
| FEC | FAM.FT.BNST | FEC.FT.SNC.MED | Substantia Nigra Pars Compacta Medial | nucleus-nucleus | (unknown reference) |
| FMM | FAM.FT.AM.MPV | FMM.FD.TH.RE | Reuniens Nucleus of Thalamus | nucleus-nucleus-gaba | Oculomotor decision-making (AMYG -> Thalamus, abstract) |
| FAM.FT.SEP.BAC | FMM.FT.HF.SUBP | Proximal Subiculum | nucleus-allocortex | Medial mammillary nucleus and theta rhythm (SEP -> HF, abstract) | |
| LAC | FAM.FT.AM.MEA | LAC.FD.HT.VLPO | Ventrolateral Preoptic Nucleus | nucleus-nucleus | Role for serotonin in moral behavior (AMY -> HYP, abstract) |
| FAM.FT.AM.MPD | LAC.FD.HT.MPO | Median Preoptic Nucleus | nucleus-nucleus-gaba | Role for serotonin in moral behavior (AMY -> HYP, abstract) | |
| LAC.FD.HT.PV | Paraventricular Nucleus | nucleus-nucleus-gaba | Amygdalar disruption of prefrontal cortex (AM -> HT.PV, abstract) | ||
| FAM.FT.AM.MPV | LAC.FD.HT.PRM | Premammillary Nucleus | nucleus-nucleus-gaba | Amygdalar disruption of prefrontal cortex (AM -> HT.L, abstract) | |
| LAC.FD.HT.VM | Ventromedial Hypothalamic Nucleus | nucleus-nucleus-gaba | Role for serotonin in moral behavior (AMY -> HYP, abstract) | ||
| LMC | FAM.FT.BNST | LMC.FT.NBM | Basal Nucleus of Meynert | nucleus-nucleus | (unknown reference) |
| LMC.HT.LC | Locus Coeruleus | nucleus-nucleus | (unknown reference) | ||
| LMC.MM.VTA | Ventral Tegmental Area | nucleus-nucleus | (unknown reference) | ||
| LPC | FAM.FT.IPAC.MED | LPC.HL.SOL | Solitary Nucleus | nucleus-nucleus | (unknown reference) |
| LPC.HT.PRF.PB | Parabrachial Nucleus | nucleus-nucleus | (unknown reference) |
Express Fight Emotions
| Component ID | Component Name | Type | Service | Function | Comments |
| FAM.FT.AM.CEM | Medial Central Amygdaloid Nucleus | nucleus | FAU | mediate behavioral responses, output projections | |
| FAM.FT.SEP.SH | Septohippocampal Nucleus | nucleus | FAU | participate in solving conflict between two or more competing goals, defensive circuit |
Internal Region Connections:
- no connections
External Inbound Region Connections:
| Source Area | Local Region | Source Region | Source Name | Type | Reference |
| Cortical | |||||
| NDM | FAM.FT.SEP.SH | NDM.NC.AL.FPC | Lateral Frontopolar Cortex | neocortex-nucleus | (unknown reference) |
| Subcortical | |||||
| FAM | FAM.FT.AM.CEM | FAM.FT.AM.AB | Accessory Basal Amygdaloid Nucleus | nucleus-nucleus | Summary of the main extra-amygdaloid and intra-amygdaloid connections in the rat (AB -> CE, abstract) |
| FAM.FT.AM.BP | Parvicellular Basal Amygdaloid Nucleus | nucleus-nucleus | Amygdala and its network (BLN -> CEA, abstract) | ||
| FAM.FT.AM.CEC | Central Amygdaloid Nucleus, capsular subdivision | nucleus-nucleus | (unknown reference) | ||
| FAM.FT.AM.CEL | Central Amygdaloid Nucleus, lateral subdivision | nucleus-nucleus | (unknown reference) | ||
| FAM.FT.AM.ITC | Intercalated Amygdaloid Nuclei | nucleus-nucleus-gaba | (unknown reference) | ||
| FAM.FT.AM.MEA | Medial Anterior Amygdaloid Nucleus | nucleus-nucleus | Body alarm system (MED -> CE, abstract) | ||
| FEC | FAM.FT.AM.CEM | FEC.FT.SNC.MED | Substantia Nigra Pars Compacta Medial | nucleus-nucleus-DA | (unknown reference) |
External Outbound Region Connections:
| Target Area | Local Region | Target Region | Target Name | Type | Reference |
| Subcortical | |||||
| FAM | FAM.FT.AM.CEM | FAM.FT.SEP.LT | Lateral Septal Nucleus | nucleus-nucleus | (unknown reference) |
| LAC | FAM.FT.AM.CEM | LAC.FD.HT.LTN | Lateral Hypothalamic Nucleus | nucleus-nucleus | Amygdalar disruption of prefrontal cortex (AM -> HT.L, abstract) |
| LAC.HL.VGN | Vagus Nucleus | nucleus-nucleus | Amygdala and its network (CEA -> VGDM, abstract) | ||
| FAM.FT.SEP.SH | LAC.FD.HT.LTN | Lateral Hypothalamic Nucleus | nucleus-nucleus | Cingulate Gyrus (SEP -> HT, abstract) | |
| LMC | FAM.FT.AM.CEM | LMC.FT.NBM | Basal Nucleus of Meynert | nucleus-nucleus | (unknown reference) |
| LMC.HT.LC | Locus Coeruleus | nucleus-nucleus | Amygdalar disruption of prefrontal cortex (AM -> LC, abstract) | ||
| LMC.MM.PAG | Periaqueductal Gray Matter | nucleus-nucleus | Amygdalar disruption of prefrontal cortex (AM -> PAG, abstract) |
Solving Fight-Flight Dilemma
| Component ID | Component Name | Type | Service | Function | Comments |
| FAM.FT.SEP.LT | Lateral Septal Nucleus | nucleus | FAU | promote active stress coping behavior |
Internal Region Connections:
- no connections
External Inbound Region Connections:
| Source Area | Local Region | Source Region | Source Name | Type | Reference |
| Subcortical | |||||
| FAM | FAM.FT.SEP.LT | FAM.FT.AM.CEM | Medial Central Amygdaloid Nucleus | nucleus-nucleus | (unknown reference) |
| FAM.FT.AM.MPV | Medial Posterior Ventral Amygdaloid Nucleus | nucleus-nucleus-gaba | (unknown reference) | ||
| FMM | FAM.FT.SEP.LT | FMM.FT.HC.CA1D | Distal CA1 of Hippocampus | allocortex-nucleus | Connectivity map of the habenula (Hippo -> Septum, abstract) |
| LAC | FAM.FT.SEP.LT | LAC.FD.HT.PN | Posterior Hypothalamic Nucleus | nucleus-nucleus | (unknown reference) |
| LAC.FD.HT.TBM | Tuberomammillary Nucleus | nucleus-nucleus | (unknown reference) | ||
| LMC | FAM.FT.SEP.LT | LMC.MM.RF.SUC | Superior Central Raphe Nucleus | nucleus-nucleus-5HT | (unknown reference) |
External Outbound Region Connections:
| Target Area | Local Region | Target Region | Target Name | Type | Reference |
| Subcortical | |||||
| FAM | FAM.FT.SEP.LT | FAM.FD.LHB.MED | Lateral Habenula Medial Part | nucleus-nucleus-gaba | Both LHb and MHb control the dopaminergic and serotonergic systems (LS -> LHbM) |
| LAC | FAM.FT.SEP.LT | LAC.FD.HT.VLPO | Ventrolateral Preoptic Nucleus | nucleus-nucleus-gaba | Cingulate Gyrus (SEP -> HT, abstract) |
| LPC | FAM.FT.SEP.LT | LPC.FD.TH.PV | Paraventricular Nucleus of Thalamus | nucleus-nucleus-gaba | (unknown reference) |
Memory Formation Affective Focus
| Component ID | Component Name | Type | Service | Function | Comments |
| FAM.FT.SEP.DBB | Diagonal Band of Broca | nucleus | FAU | involved in generation of theta waves in hippocampus | ACh and GABA; ventral group - from stria terminalis to/from MFB |
| FAM.FT.SEP.MED | Medial Septal Nucleus | nucleus | FAU | affect HC for spatial learning, generation of theta waves | output nucleus; projections from AM and HC overlap; control theta rythm and exprolatory behavior; from/to MFB to fornix fimbria |
Internal Region Connections:
- no connections
External Inbound Region Connections:
| Source Area | Local Region | Source Region | Source Name | Type | Reference |
| Subcortical | |||||
| LAC | FAM.FT.SEP.DBB | LAC.FD.HT.SUM | Supramammillary Nucleus | nucleus-nucleus | Medial mammillary nucleus and theta rhythm (SupraMM -> SEP, abstract) |
| FAM.FT.SEP.MED | LAC.FD.HT.SUM | Supramammillary Nucleus | nucleus-nucleus | Medial mammillary nucleus and theta rhythm (SupraMM -> SEP, abstract) | |
| LMC | FAM.FT.SEP.DBB | LMC.HT.LC | Locus Coeruleus | nucleus-nucleus-NE | (unknown reference) |
External Outbound Region Connections:
Reward Emotions Control
| Component ID | Component Name | Type | Service | Function | Comments |
| FAM.FD.MHB | Medial Habenula | nucleus | FAU | Encoding negative feedback, indirect | affects VTA, dorsal raphe but via interpeduncular nucleus |
| FAM.FT.EPF | Endopiriform Nucleus | nucleus | FAU | Putative relay of limbic-associated cortical-like areas subserving affective information |
|
| FAM.HT.TG.NI | Incertus Nucleus | nucleus | LUS | Behavioural activation and the response to stress | Modulating influences on prefrontal and hippocampal cortical activity, midline behavior control; modulatory nucleus; relay from reticularis pontis oralis nucleus to septo-hippocampal system |
Internal Region Connections:
| Source Region | Target Region | Type | Reference |
| FAM.HT.TG.NI | FAM.FT.EPF | nucleus-nucleus-gaba | (unknown reference) |
External Inbound Region Connections:
External Outbound Region Connections:
| Target Area | Local Region | Target Region | Target Name | Type | Reference |
| Cortical | |||||
| NCP | FAM.FT.EPF | NCP.NC.INS.AIC | Anterior Insular Cortex | nucleus-neocortex | Gustatory sensory system of rat and macaque (EnP -> Iav, abstract) |
| Subcortical | |||||
| FAM | FAM.FD.MHB | FAM.FD.LHB.MED | Lateral Habenula Medial Part | nucleus-nucleus | Connectivity map of the habenula (M -> L, abstract) |
| FAM.FT.EPF | FAM.FD.LHB.LT | Lateral Habenula Lateral Part | nucleus-nucleus | Regulation of the rapid eye movement (REM) sleep by habenular projection (EPN -> LHbL) | |
| FAM.HT.TG.NI | FAM.FT.SEP.SF | Septofimbrial Nucleus | nucleus-nucleus-gaba | (unknown reference) | |
| FAM.FT.SEP.TR | Triangular Septal Nucleus | nucleus-nucleus-gaba | (unknown reference) | ||
| FEC | FAM.FD.MHB | FEC.HT.PPN.IPD | Interpeduncular Nucleus | nucleus-nucleus | Connectivity map of the habenula (M -> IPN) |
| FMM | FAM.HT.TG.NI | FMM.NC.PH.PER | Perirhinal Cortex | nucleus-neocortex-gaba | (unknown reference) |
| Target | |||||
| TEA | FAM.FD.MHB | TARGET.TEA.ENDOCRINE | Endocrine Glands | endocrine-pineal-gland | Habenula Connections (MHb -> PB) |
Fast Unconditional Sensory Data and Association Memory
| Component ID | Component Name | Type | Service | Function | Comments |
| FAM.FT.AM.CEC | Central Amygdaloid Nucleus, capsular subdivision | nucleus | FAU | mediate behavioral responses, link to striatal effect | gustatory, somatosensory, visual, auditory, frontal cortex, perirhinal cortex, ET, SUB -> X -> HT-dl/cl, CeM |
| FAM.FT.AM.CEL | Central Amygdaloid Nucleus, lateral subdivision | nucleus | FAU | mediate behavioral responses, link to gustatory and visceral aspects of reinforcement |
contributions of food prediction and food presentation |
| FAM.FT.AM.COP | Posterior Cortical Amygdaloid Nucleus | nucleus | FAU | olfactory processing - unconditional signaling | |
| FAM.FT.AM.LAVL | Ventrolateral Amygdaloid Nucleus | nucleus | FAU | unconditional stimulus input - visual, auditory and somatic, convergence from thalamus |
LA1; LGN, MGBm, PIL |
| FAM.FT.AM.LAVM | Ventromedial Amygdaloid Nucleus | nucleus | FAU | conditional and unconditional convergence to affect polymodal memory formation | LA3; projects to ET |
Internal Region Connections:
- no connections
External Inbound Region Connections:
External Outbound Region Connections:
| Target Area | Local Region | Target Region | Target Name | Type | Reference |
| Subcortical | |||||
| FAM | FAM.FT.AM.CEC | FAM.FT.AM.CEM | Medial Central Amygdaloid Nucleus | nucleus-nucleus | (unknown reference) |
| FAM.FT.AM.CEL | FAM.FT.AM.CEM | Medial Central Amygdaloid Nucleus | nucleus-nucleus | (unknown reference) | |
| FAM.FT.BNST | Bed Nucleus of Stria Terminalis | nucleus-nucleus | (unknown reference) | ||
| FAM.FT.AM.COP | FAM.FT.AM.MEA | Medial Anterior Amygdaloid Nucleus | nucleus-nucleus | (unknown reference) | |
| FAM.FT.AM.LAVL | FAM.FT.AM.BP | Parvicellular Basal Amygdaloid Nucleus | nucleus-nucleus | Amygdala and its network (LA -> BLN, abstract) | |
| FAM.FT.AM.LAVM | FAM.FT.AM.AB | Accessory Basal Amygdaloid Nucleus | nucleus-nucleus | Summary of the main extra-amygdaloid and intra-amygdaloid connections in the rat (L -> AB, abstract) | |
| FAM.FT.AM.MPV | Medial Posterior Ventral Amygdaloid Nucleus | nucleus-nucleus | Summary of the main extra-amygdaloid and intra-amygdaloid connections in the rat (L -> M, abstract) | ||
| FMM | FAM.FT.AM.LAVL | FMM.NC.PH.PAS | Parasubiculum | nucleus-neocortex | Detailed amygdalohippocampal projections (L -> PaS, abstract) |
| LAC | FAM.FT.AM.COP | LAC.FD.HT.SO | Supraoptic Nucleus | nucleus-nucleus | Role for serotonin in moral behavior (AMY -> HYP, abstract) |
| LPC | FAM.FT.AM.CEL | LPC.HL.SOL | Solitary Nucleus | nucleus-nucleus | (unknown reference) |
| FAM.FT.AM.LAVM | LPC.FD.TH.PV | Paraventricular Nucleus of Thalamus | nucleus-nucleus | Oculomotor decision-making (AMYG -> Thalamus, abstract) | |
| LPC.MM.CIC | Central Nucleus of Inferior Colliculus | nucleus-nucleus | Visual-Auditory Interactions in Tectum (AM -> IC, abstract) |
Thirdparty Circuits
(generated)
- Body alarm system - see Reference
- Fear regulation - see Reference
References
(generated)
- http://www.nature.com/neuro/journal/v17/n9/fig_tab/nn.3779_F2.html
- http://journal.frontiersin.org/article/10.3389/fnhum.2013.00826/full
- http://thebrain.mcgill.ca/flash/i/i_04/i_04_cl/i_04_cl_peu/i_04_cl_peu.html
- https://books.google.ru/books?id=P3fSBwAAQBAJ
- http://www.scholarpedia.org/article/Habenula
- http://jn.physiology.org/content/107/10/2633
- http://www.sciencedirect.com/science/article/pii/S0149763401000215
- http://www.nature.com/npp/journal/v35/n1/fig_tab/npp2009104f10.html
- https://brmlab.cz/project/brain_hacking/tdcs/pfc
- http://www.surgicalneurologyint.com/article.asp?issn=2152-7806;year=2012;volume=3;issue=2;spage=40;epage=46;aulast=Langevin
- http://journal.frontiersin.org/article/10.3389/fphar.2014.00068/full
- http://www.sciencedirect.com/science/article/pii/S0149763415002055
- http://dgr.brain.riken.jp/AsymmetryE.html
- http://www.nature.com/nrn/journal/v11/n6/fig_tab/nrn2849_F7.html
- http://rstb.royalsocietypublishing.org/content/364/1519/1005
