BrainRegionLAC FD HT PV
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Paraventricular Nucleus
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This page covers biological details of component Paraventricular Nucleus. Region is part of aHuman target integrated biological model.
- Top-down path to region: Forebrain Diencephalon -> Hypothalamus (FD.HT) -> Anterior Hypothalamus Area (LAC.FD.HT.AHT) -> Tuberal Area (LAC.FD.HT.TUB) -> Paraventricular Nucleus (LAC.FD.HT.PV) (see Mind Maps)
- Type: nucleus
- Quality: L0
- Brain area: Lower Brain - Autonomous Control Area (LAC)
- Area circuit: Thirst and Hunger Control (LATH)
- Role: processor.autonomic
- Function: Regulate appetite and autonomic functions
(generated)
Components
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Component items:
- Paraventricular Nucleus of Hypothalamus Magnocellular Division
- Paraventricular Nucleus of Hypothalamus Magnocellular Division - Anterior Magnocellular Part
- Paraventricular Nucleus of Hypothalamus Magnocellular Division - Medial Magnocellular Part
- Paraventricular Nucleus of Hypothalamus Magnocellular Division - Posterior Magnocellular Part
- Paraventricular Nucleus of Hypothalamus Magnocellular Division - Posterior Magnocellular Part Lateral Zone
- Paraventricular Nucleus of Hypothalamus Magnocellular Division - Posterior Magnocellular Part Medial Zone
- Paraventricular Nucleus of Hypothalamus Parvicellular Division
- Paraventricular Nucleus of Hypothalamus Descending Division
- Paraventricular Nucleus of Hypothalamus Descending Division - Dorsal Parvicellular Part
- Paraventricular Nucleus of Hypothalamus Descending Division - Forniceal Part
- Paraventricular Nucleus of Hypothalamus Descending Division - Lateral Parvicellular Part
- Paraventricular Nucleus of Hypothalamus Descending Division - Medial Parvicellular Part, Ventral Zone
Connectivity
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Inbound Region Connections:
Outbound Region Connections:
Target Area | Target Region | Target Name | Type | Role | Reference |
LAC | LAC.SC.CC.DCN | Dorsal Commissural Nucleus | excitatory-glu | uncertain | (unknown reference) |
LAC.SC.IZ.CSC | Ciliospinal Center | excitatory-glu | uncertain | Effect of light on pupil diameter (PVN -> IML) | |
LAC.SC.IZ.SPS | Sacral Parasympathetic Nucleus | excitatory-glu | uncertain | (unknown reference) | |
LAC.SC.LH.LSN | Lateral Spinal Nucleus | excitatory-glu | uncertain | (unknown reference) | |
LMC | LMC.HL.RP.MG | Raphe Magnus Nucleus | excitatory-glu | uncertain | (unknown reference) |
LPC | LPC.SC.VH.ONF | Onuf's Nucleus | excitatory-glu | uncertain | (unknown reference) |
NDM | NDM.NC.AL.ROFCS | Sulcal Rostral Orbitofrontal Cortex | excitatory-glu | uncertain | Bowels control brain: gut hormones and obesity (PVN -> OFC, abstract) |
TEA | TARGET.TEA.ENDOCRINE | Endocrine Glands | endocrine-neurohypophysis-oxytocin | (none) | Amygdalar disruption of prefrontal cortex (HT.PV -> PUT) |
Thirdparty Circuits
(generated)
- Schematic of hypothalamic circuitry underlying satiety - see Reference (CP.SATIETY)
ARC=Arcuate Nucleus of Hypothalamus,LAC.FD.HT.AR DMH=Dorsomedial Hypothalamic Nucleus,LAC.FD.HT.DM LHA=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN NTS=Solitary Nucleus,LPC.HL.SOL PVN=Paraventricular Nucleus,LAC.FD.HT.PV VMH=Ventromedial Hypothalamic Nucleus,LAC.FD.HT.VM
- Effect of light on pupil diameter - see Reference (CP.PUPIL-REFLEX)
DMH=Dorsomedial Hypothalamic Nucleus,LAC.FD.HT.DM EW=Edinger-Westphal Nucleus,LAC.MM.EWN EYE=Eye,TARGET.TSA.EYE GC=Ciliary Ganglion,LAC.PN.PSYM.CLG IML=Ciliospinal Center,LAC.SC.IZ.CSC LC=Locus Coeruleus,LMC.HT.LC OPN=Pretectal Olivary Nucleus,LRC.MM.PT.PON PVN=Paraventricular Nucleus,LAC.FD.HT.PV RET=Retinal Nucleus,LPC.FD.RT SCG=Superior Cervical Ganglion,LAC.PN.SYM.SCG SCN=Suprachiasmatic Nucleus,LAC.FD.HT.SCN
- Bowels control brain: gut hormones and obesity - see Reference (CP.BOWELS)
AMY=Amygdala,FAM.FT.AM ARC=Arcuate Nucleus of Hypothalamus,LAC.FD.HT.AR DS=Dorsal Striatum,FEC.FT.DST (see Basal Ganglia) LHA=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN ME=Endocrine Glands,TARGET.TEA.ENDOCRINE NAc=Accumbens Nucleus,FEC.FT.ACC (see Basal Ganglia) NTS=Solitary Nucleus,LPC.HL.SOL OFC=Orbitofrontal Cortex,NC.AL.OPFC (see Orbitomedial Prefrontal Cortex) PBN=Parabrachial Nucleus,LPC.HT.PRF.PB PVN=Paraventricular Nucleus,LAC.FD.HT.PV VMN=Ventromedial Hypothalamic Nucleus,LAC.FD.HT.VM VTA=Ventral Tegmental Area,LMC.MM.VTA
- Amygdalar disruption of prefrontal cortex - see Reference (CF.AM-DISRUPTION)
ACG=Anterior Cingulate Cortex,NC.AL.ACG (see Anterior Cingulate Area) AM=Amygdala,FAM.FT.AM HC=Hippocampus,FMM.FT.HC (see Hippocampal Formation) HT.L=Lateral Hypothalamic Area,LAC.FD.HT.LT (see Hypothalamus) HT.PV=Paraventricular Nucleus,LAC.FD.HT.PV INS=Insular Cortex,NC.INS LC=Locus Coeruleus,LMC.HT.LC MPFC=Orbitofrontal Cortex,NC.AL.OPFC (see Orbitomedial Prefrontal Cortex) PAG=Periaqueductal Gray Matter,LMC.MM.PAG PB=Parabrachial Nucleus,LPC.HT.PRF.PB PUT=Endocrine Glands,TARGET.TEA.ENDOCRINE SOL=Solitary Nucleus,LPC.HL.SOL TH=Thalamus,FD.TH
- Glucose-sensing neural network - see Reference (CP.GLUCOSE)
ARC=Arcuate Nucleus of Hypothalamus,LAC.FD.HT.AR DMN=Dorsomedial Hypothalamic Nucleus,LAC.FD.HT.DM LHA=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN PVH=Paraventricular Nucleus,LAC.FD.HT.PV VMH=Ventromedial Hypothalamic Nucleus,LAC.FD.HT.VM
- Food-entrainable circadian oscillator - see Reference (CP.FOOD-OCSILLATOR)
DMH=Dorsomedial Hypothalamic Nucleus,LAC.FD.HT.DM LH=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN NTS=Solitary Nucleus,LPC.HL.SOL PBN=Parabrachial Nucleus,LPC.HT.PRF.PB PVH=Paraventricular Nucleus,LAC.FD.HT.PV SCN=Suprachiasmatic Nucleus,LAC.FD.HT.SCN
- Eating and sleeping to survive - see Reference (CP.DMH-CYCLES)
ARC=Arcuate Nucleus of Hypothalamus,LAC.FD.HT.AR DMH=Dorsomedial Hypothalamic Nucleus,LAC.FD.HT.DM LHA=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN MPO=Median Preoptic Nucleus,LAC.FD.HT.MPO PVH=Paraventricular Nucleus,LAC.FD.HT.PV SCN=Suprachiasmatic Nucleus,LAC.FD.HT.SCN VLPO=Ventrolateral Preoptic Nucleus,LAC.FD.HT.VLPO VMH=Ventromedial Hypothalamic Nucleus,LAC.FD.HT.VM
- Physiology and pathophysiology of lower urinary tract - see Reference (CM.ONUF)
CN=Caudate Nucleus,FEC.FT.CN (see Basal Ganglia) DVM=Vagus Nucleus,LAC.HL.VGN IMG=Inferior Mesenteric Ganglion,LAC.PN.SYM.IMG IML=Intermediolateral Nucleus,LAC.SC.IZ.IML LC=Locus Coeruleus,LMC.HT.LC MPFC=Orbitofrontal Cortex,NC.AL.OPFC (see Orbitomedial Prefrontal Cortex) MPOA=Median Preoptic Nucleus,LAC.FD.HT.MPO NBM=Basal Nucleus of Meynert,LMC.FT.NBM ONF=Onuf's Nucleus,LPC.SC.VH.ONF PBN=Parabrachial Nucleus,LPC.HT.PRF.PB PEL=Pelvic Peripheral Ganglion,LAC.PN.PSYM.PPG PU=Dorsal Putamen Lateral,FEC.FT.PU.LT PVN=Paraventricular Nucleus,LAC.FD.HT.PV SNC=Substantia Nigra Pars Compacta Lateral,FEC.FT.SNC.LT SPS=Sacral Parasympathetic Nucleus,LAC.SC.IZ.SPS VTA=Ventral Tegmental Area,LMC.MM.VTA ZI=Subthalamic Nucleus Caudal,BGA.FD.STN.ZI
- Intrahypothalamic connections important for neural control of food intake and energy balance - see Reference (CL.INTRAHYPOTHALAMIC)
AH=Anterior Hypothalamic Nucleus,LAC.FD.HT.AH ARC=Arcuate Nucleus of Hypothalamus,LAC.FD.HT.AR DMN=Dorsomedial Hypothalamic Nucleus,LAC.FD.HT.DM LHA=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN MPOA=Median Preoptic Nucleus,LAC.FD.HT.MPO PA=Paraventricular Nucleus,LAC.FD.HT.PV SCH=Suprachiasmatic Nucleus,LAC.FD.HT.SCN SON=Supraoptic Nucleus,LAC.FD.HT.SO VMN=Ventromedial Hypothalamic Nucleus,LAC.FD.HT.VM
References
(generated)
- http://neuroscience.uth.tmc.edu/s4/chapter04.html
- http://journal.frontiersin.org/article/10.3389/fnint.2012.00094/full
- http://www.nature.com/nrendo/journal/v6/n8/fig_tab/nrendo.2010.93_F1.html
- http://neuropolitics.org/defaultmay10.asp
- http://ajpregu.physiology.org/content/302/2/R215
- http://www.pnas.org/content/103/32/12150/F7.expansion.html
- http://www.dana.org/Publications/ReportDetails.aspx?id=44217
- http://www.intechopen.com/books/computational-intelligence-in-electromyography-analysis-a-perspective-on-current-applications-and-future-challenges/sphincter-emg-for-diagnosing-multiple-system-atrophy-and-related-disorders
- http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.122.2314rep=rep1type=pdf