BrainRegionLAC FD HT VM
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Ventromedial Hypothalamic Nucleus
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This page covers biological details of component Ventromedial Hypothalamic Nucleus. Region is part of aHuman target integrated biological model.
- Top-down path to region: Forebrain Diencephalon -> Hypothalamus (FD.HT) -> Anterior Hypothalamus Area (LAC.FD.HT.AHT) -> Tuberal Area (LAC.FD.HT.TUB) -> Ventromedial Hypothalamic Nucleus (LAC.FD.HT.VM) (see Mind Maps)
- Type: nucleus
- Quality: L0
- Brain area: Lower Brain - Autonomous Control Area (LAC)
- Area circuit: Thirst and Hunger Control (LATH)
- Role: processor.autonomic
- Function: Satiety, control of eating
- Notes to function:
- medial of tuberculum
(generated)
Components
(generated)
- no child items defined
Connectivity
(generated)
Inbound Region Connections:
| Source Area | Source Region | Source Name | Type | Role | Reference |
| FAM | FAM.FT.AM.MPV | Medial Posterior Ventral Amygdaloid Nucleus | inhibitory-gaba | uncertain | Role for serotonin in moral behavior (AMY -> HYP, abstract) |
| FMM | FMM.FT.HF.SUBP | Proximal Subiculum | excitatory-glu | uncertain | (unknown reference) |
| LAC | LAC.FD.HT.AH | Anterior Hypothalamic Nucleus | excitatory-glu | uncertain | Intrahypothalamic connections important for neural control of food intake and energy balance (AH -> VMN) |
| LAC.FD.HT.AR | Arcuate Nucleus of Hypothalamus | excitatory-glu | uncertain | Schematic of hypothalamic circuitry underlying satiety (ARC -> VMH) | |
| LAC.FD.HT.PRM | Premammillary Nucleus | excitatory-glu | uncertain | (unknown reference) |
Outbound Region Connections:
| Target Area | Target Region | Target Name | Type | Role | Reference |
| FAM | FAM.FT.BNST | Bed Nucleus of Stria Terminalis | excitatory-glu | uncertain | (unknown reference) |
| FEC | FEC.FD.STN.CD | Subthalamic Nucleus Caudal | excitatory-glu | uncertain | (unknown reference) |
| FEC.FT.ACC.SH | Nucleus Accumbens Shell | excitatory-glu | uncertain | Bowels control brain: gut hormones and obesity (VMN -> NAc, abstract) | |
| LAC | LAC.FD.HT.DM | Dorsomedial Hypothalamic Nucleus | excitatory-glu | uncertain | Intrahypothalamic connections important for neural control of food intake and energy balance (VMN -> DMN) |
| LAC.FD.HT.LTN | Lateral Hypothalamic Nucleus | excitatory-glu | uncertain | Glucose-sensing neural network (VMH -> LHA) | |
| LAC.FD.HT.PV | Paraventricular Nucleus | excitatory-glu | uncertain | Glucose-sensing neural network (VMH -> PVH) | |
| LAC.FD.HT.VLPO | Ventrolateral Preoptic Nucleus | excitatory-glu | uncertain | (unknown reference) | |
| LPC | LPC.HL.SOL | Solitary Nucleus | excitatory-glu | uncertain | Bowels control brain: gut hormones and obesity (VMN -> NTS) |
Thirdparty Circuits
(generated)
- Glucose-sensing neural network - see Reference (CP.GLUCOSE)
ARC=Arcuate Nucleus of Hypothalamus,LAC.FD.HT.AR DMN=Dorsomedial Hypothalamic Nucleus,LAC.FD.HT.DM LHA=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN PVH=Paraventricular Nucleus,LAC.FD.HT.PV VMH=Ventromedial Hypothalamic Nucleus,LAC.FD.HT.VM
- Bowels control brain: gut hormones and obesity - see Reference (CP.BOWELS)
AMY=Amygdala,FAM.FT.AM ARC=Arcuate Nucleus of Hypothalamus,LAC.FD.HT.AR DS=Dorsal Striatum,FEC.FT.DST (see Basal Ganglia) LHA=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN ME=Endocrine Glands,TARGET.TEA.ENDOCRINE NAc=Accumbens Nucleus,FEC.FT.ACC (see Basal Ganglia) NTS=Solitary Nucleus,LPC.HL.SOL OFC=Orbitofrontal Cortex,NC.AL.OPFC (see Orbitomedial Prefrontal Cortex) PBN=Parabrachial Nucleus,LPC.HT.PRF.PB PVN=Paraventricular Nucleus,LAC.FD.HT.PV VMN=Ventromedial Hypothalamic Nucleus,LAC.FD.HT.VM VTA=Ventral Tegmental Area,LMC.MM.VTA
- Intrahypothalamic connections important for neural control of food intake and energy balance - see Reference (CL.INTRAHYPOTHALAMIC)
AH=Anterior Hypothalamic Nucleus,LAC.FD.HT.AH ARC=Arcuate Nucleus of Hypothalamus,LAC.FD.HT.AR DMN=Dorsomedial Hypothalamic Nucleus,LAC.FD.HT.DM LHA=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN MPOA=Median Preoptic Nucleus,LAC.FD.HT.MPO PA=Paraventricular Nucleus,LAC.FD.HT.PV SCH=Suprachiasmatic Nucleus,LAC.FD.HT.SCN SON=Supraoptic Nucleus,LAC.FD.HT.SO VMN=Ventromedial Hypothalamic Nucleus,LAC.FD.HT.VM
- Schematic of hypothalamic circuitry underlying satiety - see Reference (CP.SATIETY)
ARC=Arcuate Nucleus of Hypothalamus,LAC.FD.HT.AR DMH=Dorsomedial Hypothalamic Nucleus,LAC.FD.HT.DM LHA=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN NTS=Solitary Nucleus,LPC.HL.SOL PVN=Paraventricular Nucleus,LAC.FD.HT.PV VMH=Ventromedial Hypothalamic Nucleus,LAC.FD.HT.VM
- Eating and sleeping to survive - see Reference (CP.DMH-CYCLES)
ARC=Arcuate Nucleus of Hypothalamus,LAC.FD.HT.AR DMH=Dorsomedial Hypothalamic Nucleus,LAC.FD.HT.DM LHA=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN MPO=Median Preoptic Nucleus,LAC.FD.HT.MPO PVH=Paraventricular Nucleus,LAC.FD.HT.PV SCN=Suprachiasmatic Nucleus,LAC.FD.HT.SCN VLPO=Ventrolateral Preoptic Nucleus,LAC.FD.HT.VLPO VMH=Ventromedial Hypothalamic Nucleus,LAC.FD.HT.VM
- Spine induction on short primary dendrites in the ventrolateral VMH - see Reference (CL.VMH-PAG)
PAG=Periaqueductal Gray Matter,LMC.MM.PAG VMH=Ventromedial Hypothalamic Nucleus,LAC.FD.HT.VM
References
(generated)
- http://ajpregu.physiology.org/content/302/2/R215
- http://www.nature.com/nrendo/journal/v6/n8/fig_tab/nrendo.2010.93_F1.html
- http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.122.2314rep=rep1type=pdf
- http://neuroscience.uth.tmc.edu/s4/chapter04.html
- http://www.dana.org/Publications/ReportDetails.aspx?id=44217
- http://www.jneurosci.org/content/20/4/1589/F9.expansion
