BiologicalLifeResearch
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Biological Life Research
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This page is intended to create model of biological human brain based on open research results across the world. Related findings are structured by other research themes.
Overview
- Biological Model contains Central Nervous System (CNS), Peripheral Nervous System (PNS) and human Target Sensors and Target Effectors, connected together and systematically described in machine-readable format
- Model data are divided into Engine Data (mind.xml, target.xml), Internal Model Data (hmind, muscles, nerves, global.xml) and External Model Data (circuits)
- Engine Data are divided into
- Engine Core Data (mind.xml, mind.core.xml) - most probably universal items, independent of biological nature or phenotype
- Engine Lifecycle Data (mind.lifecycle.xml) - items supporting life functions of biological organism
- Engine Specific Data (mind.specific.xml, mind.integration.xml) - nervous system items responsible for handling specific human organs
- Engine Target Data (target.xml) - final sets of human sensors and effectors
- Internal Model Data provide human-readable descriptions and additional details
- Global Circuits are independent overlapping groups of regions (global.xml) which shed light on specific modality of mind function across many Mind Areas
- External Model Data provide thirdparty models, partial and sometimes contradicting, with their own visualization and schema linked with aHuman items identification
- Engine Data are divided into
- Detailed data are grouped using two distinct structures - Brain Centers and Mind Areas
- Brain Centers are well-known anatomical groups existing as major solid structures or sets of nuclei or cortices, located on specific anatomical area
- Mind Areas are aHuman functional structures grouping items implementing major mind functions
- Every Mind Area is a set of non-overlapping Local Circuits
- Local Circuit contains specific mind regions, circuits internal inter-region connections and circuit outbound connections, which establish brain area subfunction or the same function but handling specific aspect of human organism
- Every Mind Area is a set of non-overlapping Local Circuits
See further information:
- Description of model elements and attributes - Biological Model Metadata
- Full mind hierarchy - Mind Maps
- Spinal and cranial tracts - Mind Tracts
- Peripheral nervous System - Peripheral Brain
- Nervous tissue types - Neural Networks
- Global functional circuits - Overall Circuits
- How brain is developed from the very beginning - Brain Development
Mind Areas
Approach of defining areas:
- make areas functionally named and identified
- do not create thalamus area to avoid mixing unrelated paths, assign thalamus nuclei to other areas
- do not create limbic area to avoid mixing unrelated functions, assign limbic components to other areas
- take into account all subcortical nuclei and ganglia
- all areas mapped by Brodmann placed in cortical category
- consider only single left hemisphere
- consider area as set of groups of regions and links which serve similar function, with area corresponging to providing this function in several circuits (groups)
Area Code | Area Name | Type | Function | Comments |
aHuman | ||||
TSA | Target Sensory Area | target | aHuman Target Sensors | Biological Sensors |
TEA | Target Effectory Area | target | aHuman Target Effectors | Biological Motors |
Lower Brain | ||||
LLC | Locomotion Control Area | core | Learned Rythmic Movements | Locomotion Nuclei and Cerebellum |
LAC | Autonomous Control Area | lifecycle | Autonomic Nuclei and Ganglia | Nuclei to Control Autonomic Organs and Autonomic Ganglia |
LMC | Modulatory Contol Area | lifecycle | Ascending and Descending Non-Specific Modulation | Includes Nuclei Projecting Both Up and Down |
LPC | Peripheral Control Area | specific | Conscious Control of Target | Sensory Ganglia, Conscious Sensory and Motor Nuclei |
LRC | Motor Reflex Area | specific | Reflexive Motor Behavior | Nuclei of Reflex Circuits Resulting in Motor Behavior and Posture Maintenance |
Forebrain | ||||
FEC | Execution Control Area | core | Executing Motor Sequences | Premotor and Supplemental Sequences are Wrapped out via Basal Ganglia |
FAM | Affective Motivations Area | core | Aggregate Body and Mental Motivations | Merges Top Body Feeling and Sensory Streams |
FMM | Memory Management Area | core | Establish Hierarchical Memory | Top of Sensory Hierarchy |
Neocortical Brain | ||||
NMA | Motor Aggregation Area | core | Motor Hierarhical Aggregation | Wrap Out Motor Sequences to Specific Motor Steps |
NDM | Decision Making Area | core | Sensory-Drive Associations with Working Memory | Choose Actions and Create Working Memory |
NCP | Conscious Personality Area | core | Produce Mental Feeling | Handle Pain and Errors |
NSA | Sensory Aggregation Area | specific | Unimodal Sensory Aggregation | Neocortical Sensory Data and Unimodal Aggregation |
NPE | Unimodal Execution Area | specific | Initiate Polymodal Execution | Aggregate polymodal data, direct to planning and decision making |
Brain Structure Overview
(generated)
Forebrain Diencephalon (FD):
- Habenula (FAM.FD.HB)
- Hypothalamus (FD.HT)
- Retinal Nucleus (LPC.FD.RT)
- Subthalamus Area (FEC.FD.STA)
- Thalamus
- Cognitive Thalamus (FD.TH.CR)
- Motor Thalamus (FD.TH.MR)
- Sensory Thalamus (FD.TH.SR)
Forebrain Telencephalon (FT):
- Basal Ganglia (FEC.FT.BG)
- Extended Amygdala
- Amygdala (FAM.FT.AM)
- Central Extended Amygdala (FAM.FT.CEAM)
- Septal Nuclei (FAM.FT.SEP)
- Hippocampal Formation (FMM.FT.HF)
- Olfactory Nuclei (FT.OLF)
Hindbrain Myelencephalon (HL):
- Medullary Reticular Formation (HL.RF)
- Myelencephalic Motor Nuclei (HL.MN)
- Myelencephalic Parasympathetic Nuclei (HL.PSN)
- Myelencephalic Sensory Nuclei (HL.SN)
Hindbrain Metencephalon (HT):
- Cerebellar Complex (LLC.HT.CRC)
- Locus Coeruleus (LMC.HT.LC)
- Metencephalic Motor Nuclei (HT.MN)
- Metencephalic Sensory Nuclei (HT.SN)
- Pontine Reticular Formation (HT.RF)
- Pontine Tegmental Nuclei (HT.TG)
- Vestibular Nuclei (LPC.HT.VBN)
Midbrain Mesencephalon (MM):
- Mesencephalic Reticular Formation (MM.RF)
- Perhipheral Nuclei of Midbrain Mesencephalon (MM.PER)
- Periaqueductal Gray Matter (LMC.MM.PAG)
- Red Nucleus (LLC.MM.RD)
- Reflexes Nuclei of Midbrain Mesencephalon (MM.REF)
- Ventral Tegmental Area (LMC.MM.VTA)
Cerebral Cortex (NC):
- Anterior Lobe
- Anterior Cingulate Area (NC.ACG)
- Motor Cortex (NMA.NC.MC)
- Prefrontal Cortex
- Lateral Prefrontal Cortex (NC.AL.LPFC)
- Orbitomedial Prefrontal Cortex (NC.AL.OMPFC)
- Premotor Cortex (NC.PMC)
- Supplementary Motor Cortex (NMA.NC.SMC)
- Occipital Lobe (NC.LOBE.OCC)
- Parahippocampal Lobe
- Anterior Parahippocampal Gyrus
- Retrosubicular Area (FMM.NC.PHA.RS)
- Rhinal Cortex (NC.PHA.RH)
- Posterior Parahippocampal Gyrus (FMM.NC.PHP)
- Anterior Parahippocampal Gyrus
- Parietal Lobe
- Inferior Parietal Lobule (NC.IPL)
- Intraparietal Sulcus (NSA.NC.IPS)
- Medial Parietal Lobule (NC.MPL)
- Postcentral Gyrus
- Anterior Parietal Cortex (NC.PG.APC)
- Lateral Parietal Cortex (NC.PG.LPC)
- Parietal Operculum (NC.PO)
- Superior Parietal Lobule (NC.SPL)
- Temporal Lobe
- Inferotemporal Area (NSA.NC.IT)
- Insular Cortex (NC.INS)
- Superior Temporal Gyrus (NC.STG)
- Transverse Temporal Gyrus (NSA.NC.TTG)
Peripheral Nervous System (PNS):
- Parasympathetic Ganglia
- Body Parasympathetic Ganglia (PN.PSYM.BD)
- Head and Neck Parasympathetic Ganglia (PN.PSYM.HD)
- Sensory Ganglia
- Dorsal Root Ganglia (LPC.PN.SG.DRG)
- Sensory Exteroception Ganglia (PN.SG.SE)
- Sensory Interoception Ganglia (PN.SG.SI)
- Vestibular Ganglion (LPC.PN.SG.VB)
- Sympathetic Ganglia
- Paravertebral Sympathetic Ganglia (LAC.PN.SYM.PA)
- Prevertebral Sympathetic Ganglia (LAC.PN.SYM.PR)
Spinal Cord (SC):
- Anterior/Ventral Horn (SC.VH)
- Central canal (AVA.SC.CC)
- Intermediate Zone (SC.IZ)
- Lateral Horn/Funiculus (BMA.SC.LH)
- Posterior/Dorsal Horn (BMA.SC.PH)
Target (TG):
- Human Effectors
- Blood vessels (TARGET.TEA.VESSELS)
- Breast (TARGET.TEA.BREAST)
- Endocrine Glands (TARGET.TEA.ENDOCRINE)
- Face (TARGET.TEA.FACE)
- Genitalia (TARGET.TEA.GENITALIA)
- Hand (TARGET.TEA.HAND)
- Heart (TARGET.TEA.HEART)
- Immunity glands and meninges (TARGET.TEA.PROTECTOR)
- Leg (TARGET.TEA.LEG)
- Liver (TARGET.TEA.LIVER)
- Lung (TARGET.TEA.LUNG)
- Mouth feeder (TARGET.TEA.FEEDER)
- Mouth speaker (TARGET.TEA.SPEAKER)
- Neck (TARGET.TEA.NECK)
- Rectum (TARGET.TEA.RECTUM)
- Stomach (TARGET.TEA.STOMACH)
- Trunk (TARGET.TEA.TRUNK)
- Ureter (TARGET.TEA.URETER)
- Human Sensors
Circuits
(generated)