BrainRegionFAM FT AM MPV
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Medial Posterior Ventral Amygdaloid Nucleus
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This page covers biological details of component Medial Posterior Ventral Amygdaloid Nucleus. Region is part of aHuman target integrated biological model.
- Top-down path to region: Forebrain Telencephalon -> Extended Amygdala (FAM.FT.EXTAM) -> Amygdala (FAM.FT.AM) -> Corticomedial Nuclear Complex (FAM.FT.AM.CTM) -> Centromedial Nuclei (FAM.FT.AM.CM) -> Medial Amygdala (FAM.FT.AM.M) -> Medial Posterior Ventral Amygdaloid Nucleus (FAM.FT.AM.MPV) (see Mind Maps)
- Type: nucleus
- Quality: L0
- Brain area: Forebrain - Affective Motivations Area (FAM)
- Area circuit: Express Flight Emotions (FAMXEFL)
- Role: processor.affective.flight
- Function: defensive behavior
- Notes to function:
- MePV -> LAC.FD.HT.VM (reproductive+defensive), LAC.FD.HT.AH (defensive)
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Components
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- no child items defined
Connectivity
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Inbound Region Connections:
| Source Area | Source Region | Source Name | Type | Role | Reference |
| FAM | FAM.FT.AM.LAVM | Ventromedial Amygdaloid Nucleus | excitatory-glu | uncertain | Summary of the main extra-amygdaloid and intra-amygdaloid connections in the rat (L -> M, abstract) |
| FAM.FT.AM.MEA | Medial Anterior Amygdaloid Nucleus | excitatory-glu | uncertain | (unknown reference) |
Outbound Region Connections:
| Target Area | Target Region | Target Name | Type | Role | Reference |
| FAM | FAM.FT.SEP.LT | Lateral Septal Nucleus | inhibitory-gaba | uncertain | (unknown reference) |
| FMM | FMM.FD.TH.RE | Reuniens Nucleus of Thalamus | inhibitory-gaba | uncertain | Oculomotor decision-making (AMYG -> Thalamus, abstract) |
| LAC | LAC.FD.HT.PRM | Premammillary Nucleus | inhibitory-gaba | uncertain | Amygdalar disruption of prefrontal cortex (AM -> HT.L, abstract) |
| LAC.FD.HT.VM | Ventromedial Hypothalamic Nucleus | inhibitory-gaba | uncertain | Role for serotonin in moral behavior (AMY -> HYP, abstract) |
Thirdparty Circuits
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- Oculomotor decision-making - see Reference (CP.OCULOMOTOR-DECISION-MAKING)
AMYG=Amygdala,FAM.FT.AM CGa=Anterior Cingulate Cortex,NC.AL.ACG (see Anterior Cingulate Area) CGp=Posterior Cingulate Cortex,NCP.NC.MPL.PSCG Caudate=Caudate Nucleus,FEC.FT.CN (see Basal Ganglia) FEF=Frontal Eye Field,NMA.NC.PMC.FEF (see Premotor Cortex) LIP=Lateral Intraparietal Sulcus,NPE.NC.IPS.LIP NAC=Accumbens Nucleus,FEC.FT.ACC (see Basal Ganglia) OFC=Orbitofrontal Cortex,NC.AL.OPFC (see Orbitomedial Prefrontal Cortex) PFC=Mid-Dorsolateral Prefrontal Cortex,NDM.NC.AL.DLPFC (see Lateral Prefrontal Cortex) SC=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon) SEF=Supplementary Eye Field,NPE.NC.SMC.SEF SNc=Substantia Nigra Pars Compacta Lateral,FEC.FT.SNC.LT SNr=Substantia Nigra Pars Reticulata Dorsolateral,FEC.FT.SNR.DL Thalamus=Thalamus,FD.TH VTA=Ventral Tegmental Area,LMC.MM.VTA
- Role for serotonin in moral behavior - see Reference (CF.EMOTIONAL-MODULATION)
ACG=Anterior Cingulate Cortex,NC.AL.ACG (see Anterior Cingulate Area) AMY=Amygdala,FAM.FT.AM HYP=Hypothalamus,FD.HT LPFC=Mid-Dorsolateral Prefrontal Cortex,NDM.NC.AL.DLPFC (see Lateral Prefrontal Cortex) OMPFC=Orbitofrontal Cortex,NC.AL.OPFC (see Orbitomedial Prefrontal Cortex)
- Amygdalar disruption of prefrontal cortex - see Reference (CF.AM-DISRUPTION)
ACG=Anterior Cingulate Cortex,NC.AL.ACG (see Anterior Cingulate Area) AM=Amygdala,FAM.FT.AM HC=Hippocampus,FMM.FT.HC (see Hippocampal Formation) HT.L=Lateral Hypothalamic Area,LAC.FD.HT.LT (see Hypothalamus) HT.PV=Paraventricular Nucleus,LAC.FD.HT.PV INS=Insular Cortex,NC.INS LC=Locus Coeruleus,LMC.HT.LC MPFC=Orbitofrontal Cortex,NC.AL.OPFC (see Orbitomedial Prefrontal Cortex) PAG=Periaqueductal Gray Matter,LMC.MM.PAG PB=Parabrachial Nucleus,LPC.HT.PRF.PB PUT=Endocrine Glands,TARGET.TEA.ENDOCRINE SOL=Solitary Nucleus,LPC.HL.SOL TH=Thalamus,FD.TH
References
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