BrainRegionLMC FT NBM

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Basal Nucleus of Meynert

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This page covers biological details of component Basal Nucleus of Meynert. Region is part of aHuman target integrated biological model.

  • Top-down path to region: Forebrain Telencephalon -> Extended Amygdala (FAM.FT.EXTAM) -> Central Extended Amygdala (FAM.FT.CEAM) -> Substantia innominata (FT.SIN) -> Basal Nucleus of Meynert (LMC.FT.NBM) (see Mind Maps)
  • Type: nucleus
  • Quality: L0
  • Brain area: Lower Brain - Modulatory Contol Area (LMC)
  • Area circuit: Acetylcholine - PNS Actions and CNS plasticity, arousal and reward (ACH)
  • Role: processor.autonomic
  • Function: Control imagination vs perception
  • Notes to function:
    • ACh source, attention
    • modulatory nucleus

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Components

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  • no child items defined

Connectivity

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LMC.FT.NBM.dot.png

Inbound Region Connections:

Source Area Source Region Source Name Type Role Reference
FAM FAM.FT.AM.AB Accessory Basal Amygdaloid Nucleus excitatory-glu uncertain (unknown reference)
FAM.FT.AM.BP Parvicellular Basal Amygdaloid Nucleus excitatory-glu uncertain (unknown reference)
FAM.FT.AM.CEM Medial Central Amygdaloid Nucleus excitatory-glu uncertain (unknown reference)
FAM.FT.BNST Bed Nucleus of Stria Terminalis excitatory-glu uncertain (unknown reference)
FEC FEC.FD.STN.CD Subthalamic Nucleus Caudal excitatory-glu uncertain (unknown reference)
FEC.FT.ACC.SH Nucleus Accumbens Shell inhibitory-gaba uncertain Affective basal ganglia circuit (NACC -> nBM, abstract)

Outbound Region Connections:

Target Area Target Region Target Name Type Role Reference
FAM FAM.FT.AM.BM Magnocellular Basal Amygdaloid Nucleus modulatory-ach uncertain (unknown reference)
NDM NDM.NC.AL.FPC Lateral Frontopolar Cortex modulatory-ach uncertain Physiology and pathophysiology of lower urinary tract (NBM -> MPFC, abstract)
NSA NSA.NC.OCC.V1 Primary Visual Cortex modulatory-ach uncertain (unknown reference)

Thirdparty Circuits

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CN=Caudate Nucleus,FEC.FT.CN (see Basal Ganglia)
DVM=Vagus Nucleus,LAC.HL.VGN
IMG=Inferior Mesenteric Ganglion,LAC.PN.SYM.IMG
IML=Intermediolateral Nucleus,LAC.SC.IZ.IML
LC=Locus Coeruleus,LMC.HT.LC
MPFC=Orbitofrontal Cortex,NC.AL.OPFC (see Orbitomedial Prefrontal Cortex)
MPOA=Median Preoptic Nucleus,LAC.FD.HT.MPO
NBM=Basal Nucleus of Meynert,LMC.FT.NBM
ONF=Onuf's Nucleus,LPC.SC.VH.ONF
PBN=Parabrachial Nucleus,LPC.HT.PRF.PB
PEL=Pelvic Peripheral Ganglion,LAC.PN.PSYM.PPG
PU=Dorsal Putamen Lateral,FEC.FT.PU.LT
PVN=Paraventricular Nucleus,LAC.FD.HT.PV
SNC=Substantia Nigra Pars Compacta Lateral,FEC.FT.SNC.LT
SPS=Sacral Parasympathetic Nucleus,LAC.SC.IZ.SPS
VTA=Ventral Tegmental Area,LMC.MM.VTA
ZI=Subthalamic Nucleus Caudal,BGA.FD.STN.ZI

AM=Amygdala,FAM.FT.AM
BMN=Basal Nucleus of Meynert,LMC.FT.NBM
CA1=Ventrolateral Cornu Ammonis of Hippocampus,FMM.FT.HC.CA1 (see Hippocampal Formation)
EC=Entorhinal Cortex,FMM.NC.PH.ET (see Rhinal Cortex)
PRR=Perirhinal Cortex,FMM.NC.PH.PER

NACC=Accumbens Nucleus,FEC.FT.ACC (see Basal Ganglia)
OMPFC=Orbitofrontal Cortex,NC.AL.OPFC (see Orbitomedial Prefrontal Cortex)
nBM=Basal Nucleus of Meynert,LMC.FT.NBM


References

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