BrainRegionNDM NC AL FPC

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Lateral Frontopolar Cortex

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This page covers biological details of component Lateral Frontopolar Cortex. Region is part of aHuman target integrated biological model.

  • Top-down path to region: Cerebral Cortex -> Anterior Lobe (NC.LOBE.ANT) -> Prefrontal Cortex (NC.AL.PFC) -> Orbitomedial Prefrontal Cortex (NC.AL.OMPFC) -> Orbitofrontal Cortex (NC.AL.OPFC) -> Lateral Frontopolar Cortex (NDM.NC.AL.FPC) (see Mind Maps)
  • Type: cortex
  • Quality: L0
  • Brain area: Neocortical Brain - Decision Making Area (NDM)
  • Area circuit: High-Level Control (HLC)
  • Brodmann ID: 10
  • Role: cortex.generic
  • Function: Emotion Regulation
  • Notes to function:
    • Frontopolar area, contains ILC - infralimbic cortex

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Components

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  • no child items defined

Connectivity

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NDM.NC.AL.FPC.dot.png

Inbound Region Connections:

Source Area Source Region Source Name Type Role Reference
LMC LMC.FT.NBM Basal Nucleus of Meynert modulatory-ach uncertain Physiology and pathophysiology of lower urinary tract (NBM -> MPFC, abstract)
LMC.MM.VTA Ventral Tegmental Area modulatory-da uncertain Amygdala and its network (VTA -> MPFC, abstract)
NCP NCP.NC.INS.PPC Peripaleocortical Claustral feedforward-glu uncertain Amygdalar disruption of prefrontal cortex (INS -> MPFC, abstract)
NDM NDM.FD.TH.MDM Medial Mediodorsal Nucleus of Thalamus excitatory-glu uncertain Amygdala and its network (MD -> MPFC, abstract)

Outbound Region Connections:

Target Area Target Region Target Name Type Role Reference
FAM FAM.FT.AM.BM Magnocellular Basal Amygdaloid Nucleus excitatory-glu uncertain Bowels control brain: gut hormones and obesity (OFC -> AMY, abstract)
FAM.FT.AM.BP Parvicellular Basal Amygdaloid Nucleus excitatory-glu uncertain Amygdala and its network (MPFC -> BLN, abstract)
FAM.FT.SEP.SH Septohippocampal Nucleus excitatory-glu uncertain (unknown reference)
FEC FEC.FT.ACC.CORE Nucleus Accumbens Core excitatory-glu uncertain Affective basal ganglia circuit (OMPFC -> NACC, abstract)
FEC.FT.SNR.MED Substantia Nigra Pars Reticulata Medial excitatory-glu uncertain Global visual system (FrontalCortex -> BGA, abstract)
LAC LAC.FD.HT.RCH Retrochiasmatic Nucleus excitatory-glu uncertain Prefrontal Cortex (PFC) in emotional behavior (OPFC -> HT, abstract)
NDM NDM.NC.AL.DLPFCR Rostral Mid-Dorsolateral Prefrontal Cortex feedforward-glu uncertain Prefrontal Cortex (PFC) in emotional behavior (OPFC -> LPFC, abstract)
NDM.NC.AL.VACG Ventral Anterior Cingulate Area feedforward-glu uncertain Role for serotonin in moral behavior (OMPFC -> ACG, abstract)

Thirdparty Circuits

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ATH=Anterior Nucleus of Thalamus,FD.TH.AN (see Cognitive Thalamus)
BGA=Basal Ganglia,FEC.FT.BG
FrontalCortex=Anterior Lobe,NC.LOBE.ANT
LGN=Lateral Geniculate Nucleus,NSA.FD.LGN
OPN=Oculomotor Nucleus,LPC.MM.OCN
ParietalCortex=Parietal Lobe,NC.LOBE.PAR
Pulvinar=Pulvinar,FD.PV (see Sensory Thalamus)
RF=Pontine Reticular Formation,HT.RF
Retina=Retinal Nucleus,LPC.FD.RT
SCi=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon)
SCs=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon)
SNc=Substantia Nigra Pars Compacta Lateral,FEC.FT.SNC.LT
SNr=Substantia Nigra Pars Reticulata Dorsolateral,FEC.FT.SNR.DL
SpinalCord=Lamina IX,SC.VH.L9 (see Anterior/Ventral Horn)
Striatum=Striatum,FEC.FT.ST (see Basal Ganglia)
VisualCortex=Occipital Lobe,NC.LOBE.OCC


AMY=Amygdala,FAM.FT.AM
ARC=Arcuate Nucleus of Hypothalamus,LAC.FD.HT.AR
DS=Dorsal Striatum,FEC.FT.DST (see Basal Ganglia)
LHA=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN
ME=Endocrine Glands,TARGET.TEA.ENDOCRINE
NAc=Accumbens Nucleus,FEC.FT.ACC (see Basal Ganglia)
NTS=Solitary Nucleus,LPC.HL.SOL
OFC=Orbitofrontal Cortex,NC.AL.OPFC (see Orbitomedial Prefrontal Cortex)
PBN=Parabrachial Nucleus,LPC.HT.PRF.PB
PVN=Paraventricular Nucleus,LAC.FD.HT.PV
VMN=Ventromedial Hypothalamic Nucleus,LAC.FD.HT.VM
VTA=Ventral Tegmental Area,LMC.MM.VTA


A=Anterior Nucleus of Thalamus,FD.TH.AN (see Cognitive Thalamus)
CM=Centromedian Nucleus of Thalamus,FEC.FD.TH.CM
LD=Lateral Dorsal Nucleus of Thalamus,FMM.FD.TH.LD
LGN=Lateral Geniculate Nucleus,NSA.FD.LGN
LP=Lateral Posterior Nucleus of Thalamus,NPE.FD.TH.LP
MD=Mediodorsal Nucleus of Thalamus,FD.TH.MD (see Cognitive Thalamus)
MGN=Medial Geniculate Body,NSA.FD.TH.MGB
P=Ventral Posterior Nuclei,NSA.FD.TH.VP (see Sensory Thalamus)
VA=Ventral Anterior Nucleus,NMA.FD.TH.VA
VL=Ventral Lateral Nucleus,NMA.FD.TH.VL
VPL=Ventral Posterolateral Nucleus,NCP.FD.TH.VPL
VPM=Ventral Posteromedial Nucleus,NCP.FD.TH.VPM
pA=Posterior Cingulate Cortex,NCP.NC.MPL.PSCG
pCM=Dorsal Putamen,FEC.FT.DPU (see Basal Ganglia)
pLD=Anterior Cingulate Cortex,NC.AL.ACG (see Anterior Cingulate Area)
pLGN=Primary Visual Cortex,NSA.NC.OCC.V1
pLP=Superior Parietal Lobule,NC.SPL
pMD=Prefrontal Cortex,NC.AL.PFC
pMGN=Primary Auditory Cortex,NSA.NC.TTG.A1
pP=Insular Cortex,NC.INS
pVA=Supplementary Motor Cortex,NMA.NC.SMC
pVL=Motor Cortex,NMA.NC.MC
pVPL=Primary Somatosensory Cortex,NCP.NC.PG.S1
pVPM=Precentral Cortex,NCP.NC.PO.PCC
s1A=Subiculum,FMM.FT.HF.SUB (see Hippocampal Formation)
s1MD=Septal Nuclei,FAM.FT.SEP
s1P=Central Cervical Nucleus,LPC.SC.IZ.CCV
s1VL=Dentate Nucleus,LLC.HT.CR.DN
s2A=Mammillary Body,FD.MB (see Hypothalamus)
s2MD=Piriform Cortex,NSA.NC.PH.PIR
s2P=Principal Trigeminal Nucleus,LPC.HT.PN.PTR
s2VL=Basal Ganglia,FEC.FT.BG
s3MD=Prefrontal Cortex,NC.AL.PFC
sCM=Globus Pallidus Internal,FEC.FT.GPI (see Basal Ganglia)
sLD=Superior Parietal Lobule,NC.SPL
sLP=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon)
sVA=Basal Ganglia,FEC.FT.BG
sVPL=Marginal Nucleus,LPC.SC.PH.MG (see Posterior/Dorsal Horn)
sVPM=Solitary Nucleus,LPC.HL.SOL


ACG=Anterior Cingulate Cortex,NC.AL.ACG (see Anterior Cingulate Area)
AM=Amygdala,FAM.FT.AM
HCA=Hippocampus,FMM.FT.HC (see Hippocampal Formation)
HT=Hypothalamus,FD.HT
LPFC=Mid-Dorsolateral Prefrontal Cortex,NDM.NC.AL.DLPFC (see Lateral Prefrontal Cortex)
OPFC=Orbitofrontal Cortex,NC.AL.OPFC (see Orbitomedial Prefrontal Cortex)
PCA=Medial Parietal Lobule,NC.MPL
PN=Pontine Nuclear Complex,HT.PN (see Metencephalic Sensory Nuclei)
TH=Mediodorsal Nucleus of Thalamus,FD.TH.MD (see Cognitive Thalamus)


ACG=Anterior Cingulate Cortex,NC.AL.ACG (see Anterior Cingulate Area)
AMY=Amygdala,FAM.FT.AM
HYP=Hypothalamus,FD.HT
LPFC=Mid-Dorsolateral Prefrontal Cortex,NDM.NC.AL.DLPFC (see Lateral Prefrontal Cortex)
OMPFC=Orbitofrontal Cortex,NC.AL.OPFC (see Orbitomedial Prefrontal Cortex)


NACC=Accumbens Nucleus,FEC.FT.ACC (see Basal Ganglia)
OMPFC=Orbitofrontal Cortex,NC.AL.OPFC (see Orbitomedial Prefrontal Cortex)
SNr=Substantia Nigra Pars Reticulata Medial,FEC.FT.SNR.MED
VPAL=Ventral Pallidum,FEC.FT.VP (see Basal Ganglia)
VTA=Ventral Tegmental Area,LMC.MM.VTA


BLN=Parvicellular Basal Amygdaloid Nucleus,FAM.FT.AM.BP
CEA=Central Amygdala,FAM.FT.AM.CEA (see Amygdala)
EC=Entorhinal Cortex,FMM.NC.PH.ET (see Rhinal Cortex)
HC=Hippocampus,FMM.FT.HC (see Hippocampal Formation)
HTS=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN
ITC=Inferotemporal Cortex,NSA.NC.IT.TE
LA=Lateral Amygdaloid Nucleus,FAM.FT.AM.LA (see Amygdala)
LHB=Lateral Habenula,FAM.FD.LHB (see Habenula)
MD=Mediodorsal Nucleus of Thalamus,FD.TH.MD (see Cognitive Thalamus)
MPFC=Orbitomedial Prefrontal Cortex,NC.AL.OMPFC
NACC=Accumbens Nucleus,FEC.FT.ACC (see Basal Ganglia)
PAG=Periaqueductal Gray Matter,LMC.MM.PAG
RMTG=Rostromedial Tegmental Nucleus,FEC.HT.TG.RMTG
STC=Wernicke's area A3,NSA.NC.STG.A3
VGDM=Vagus Nucleus,LAC.HL.VGN
VTA=Ventral Tegmental Area,LMC.MM.VTA


NACC=Accumbens Nucleus,FEC.FT.ACC (see Basal Ganglia)
OMPFC=Orbitofrontal Cortex,NC.AL.OPFC (see Orbitomedial Prefrontal Cortex)
nBM=Basal Nucleus of Meynert,LMC.FT.NBM


References

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