BrainRegionNDM FD TH MDM

Medial Mediodorsal Nucleus of Thalamus

@@Home -> BiologicalLifeResearch -> BrainAreaNDM -> BrainRegionNDM_FD_TH_MDM

---

This page covers biological details of component Medial Mediodorsal Nucleus of Thalamus. Region is part of aHuman target integrated biological model.

• Top-down path to region: Forebrain Diencephalon -> Thalamus (FD.TH) -> Cognitive Thalamus (FD.TH.CR) -> Mediodorsal Nucleus of Thalamus (FD.TH.MD) -> Medial Mediodorsal Nucleus of Thalamus (NDM.FD.TH.MDM) (see Mind Maps)
• Type: nucleus
• Quality: L0
• Brain area: Neocortical Brain - Decision Making Area (NDM)
• Area circuit: High-Level Control (HLC)
• Role: thalamic.cortex.reinforce
• Function: relay emotional attention to orbitofrontal cortex
• Notes to function:
  • orbitofrontal cortex (BA12,13) defined by MDm projection
  • relay AM-Bp to OFC
  • OFCm - subjective pleasantness, OFCl - subjective unpleasantness

(generated)

Components

(generated)

• no child items defined

Connectivity

(generated)

Inbound Region Connections:

Source Area	Source Region	Source Name	Type	Role	Reference
FAM	FAM.FT.AM.AB	Accessory Basal Amygdaloid Nucleus	excitatory-glu	uncertain	Prefrontal Cortex (PFC) in emotional behavior (AM -> TH, abstract)
	FAM.FT.AM.BP	Parvicellular Basal Amygdaloid Nucleus	excitatory-glu	uncertain	Amygdala and its network (BLN -> MD, abstract)
	FAM.FT.SEP.MED	Medial Septal Nucleus	modulatory-ach	uncertain	Thalamocortical relationships (s1MD -> MD, abstract)
FEC	FEC.FT.GPI.RM	Globus Pallidus Internal Rostromedial	inhibitory-gaba	uncertain	Saccadic Vision (BG -> Thalamus, abstract)
FMM	FMM.NC.PH.LEC	Lateral Entorhinal Cortex	excitatory-glu	uncertain	Contributions of Diencephalon to Recognition Memory (EC -> MDmc, abstract)
	FMM.NC.PH.PER	Perirhinal Cortex	excitatory-glu	uncertain	Contributions of Diencephalon to Recognition Memory (Perirhinal -> MDmc, abstract)
NCP	NCP.NC.MPL.PSCG	Posterior Cingulate Cortex	excitatory-glu	uncertain	Contributions of Diencephalon to Recognition Memory (PostCingulate -> MDmc, abstract)

Outbound Region Connections:

Target Area	Target Region	Target Name	Type	Role	Reference
NDM	NDM.NC.AL.DLPFCR	Rostral Mid-Dorsolateral Prefrontal Cortex	excitatory-glu	uncertain	Prefrontal Cortex (PFC) in emotional behavior (TH -> LPFC, abstract)
	NDM.NC.AL.FPC	Lateral Frontopolar Cortex	excitatory-glu	uncertain	Amygdala and its network (MD -> MPFC, abstract)

Thirdparty Circuits

(generated)

• Prefrontal Cortex (PFC) in emotional behavior - see Reference (CF.PFC-EMOTIONS)

ACG=Anterior Cingulate Cortex,NC.AL.ACG (see Anterior Cingulate Area)
AM=Amygdala,FAM.FT.AM
HCA=Hippocampus,FMM.FT.HC (see Hippocampal Formation)
HT=Hypothalamus,FD.HT
LPFC=Mid-Dorsolateral Prefrontal Cortex,NDM.NC.AL.DLPFC (see Lateral Prefrontal Cortex)
OPFC=Orbitofrontal Cortex,NC.AL.OPFC (see Orbitomedial Prefrontal Cortex)
PCA=Medial Parietal Lobule,NC.MPL
PN=Pontine Nuclear Complex,HT.PN (see Metencephalic Sensory Nuclei)
TH=Mediodorsal Nucleus of Thalamus,FD.TH.MD (see Cognitive Thalamus)

• Amygdala and its network - see Reference (CF.AM-NET)

BLN=Parvicellular Basal Amygdaloid Nucleus,FAM.FT.AM.BP
CEA=Central Amygdala,FAM.FT.AM.CEA (see Amygdala)
EC=Entorhinal Cortex,FMM.NC.PH.ET (see Rhinal Cortex)
HC=Hippocampus,FMM.FT.HC (see Hippocampal Formation)
HTS=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN
ITC=Inferotemporal Cortex,NSA.NC.IT.TE
LA=Lateral Amygdaloid Nucleus,FAM.FT.AM.LA (see Amygdala)
LHB=Lateral Habenula,FAM.FD.LHB (see Habenula)
MD=Mediodorsal Nucleus of Thalamus,FD.TH.MD (see Cognitive Thalamus)
MPFC=Orbitomedial Prefrontal Cortex,NC.AL.OMPFC
NACC=Accumbens Nucleus,FEC.FT.ACC (see Basal Ganglia)
PAG=Periaqueductal Gray Matter,LMC.MM.PAG
RMTG=Rostromedial Tegmental Nucleus,FEC.HT.TG.RMTG
STC=Wernicke's area A3,NSA.NC.STG.A3
VGDM=Vagus Nucleus,LAC.HL.VGN
VTA=Ventral Tegmental Area,LMC.MM.VTA

• Amygdalar disruption of prefrontal cortex - see Reference (CF.AM-DISRUPTION)

ACG=Anterior Cingulate Cortex,NC.AL.ACG (see Anterior Cingulate Area)
AM=Amygdala,FAM.FT.AM
HC=Hippocampus,FMM.FT.HC (see Hippocampal Formation)
HT.L=Lateral Hypothalamic Area,LAC.FD.HT.LT (see Hypothalamus)
HT.PV=Paraventricular Nucleus,LAC.FD.HT.PV
INS=Insular Cortex,NC.INS
LC=Locus Coeruleus,LMC.HT.LC
MPFC=Orbitofrontal Cortex,NC.AL.OPFC (see Orbitomedial Prefrontal Cortex)
PAG=Periaqueductal Gray Matter,LMC.MM.PAG
PB=Parabrachial Nucleus,LPC.HT.PRF.PB
PUT=Endocrine Glands,TARGET.TEA.ENDOCRINE
SOL=Solitary Nucleus,LPC.HL.SOL
TH=Thalamus,FD.TH

References

(generated)

• https://www.google.ru/search?hl=rutbo=ptbm=bksq=isbn:0080887988
• http://www.surgicalneurologyint.com/article.asp?issn=2152-7806;year=2012;volume=3;issue=2;spage=40;epage=46;aulast=Langevin
• http://neuropolitics.org/defaultmay10.asp