BrainRegionFEC FT SNR MED
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Substantia Nigra Pars Reticulata Medial
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This page covers biological details of component Substantia Nigra Pars Reticulata Medial. Region is part of aHuman target integrated biological model.
- Top-down path to region: Forebrain Telencephalon -> Basal Ganglia (FEC.FT.BG) -> Substantia Nigra (FEC.FT.SN) -> Substantia Nigra Pars Reticulata (FEC.FT.SNR) -> Substantia Nigra Pars Reticulata Medial (FEC.FT.SNR.MED) (see Mind Maps)
- Type: nucleus
- Quality: L0
- Brain area: Forebrain - Execution Control Area (FEC)
- Area circuit: Motor Motivational Salience (FECLM)
- Role: basal.ganglia.nigrareticulata
- Function: Motivational loop
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Components
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- no child items defined
Connectivity
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Inbound Region Connections:
| Source Area | Source Region | Source Name | Type | Role | Reference |
| FEC | FEC.FD.STN.DL | Subthalamic Nucleus Dorsolateral | excitatory-glu | uncertain | (unknown reference) |
| FEC.FT.ACC.CORE | Nucleus Accumbens Core | inhibitory-gaba | uncertain | Craving (NACC -> SNr, abstract) | |
| FEC.FT.CN.TL | Caudate Nucleus Tail | inhibitory-gaba | uncertain | Saccades and smooth movements (CN -> SN, abstract) | |
| FEC.FT.GPE.RM | Globus Pallidus External Rostromedial | inhibitory-gaba | uncertain | Prefrontal Cortex (PFC) in motor behavior (GP -> SN, abstract) | |
| FEC.FT.PU.VT | Ventral Putamen | inhibitory-gaba | uncertain | (unknown reference) | |
| FEC.FT.VP.DL | Ventral Pallidum Dorsolateral | inhibitory-gaba | uncertain | Craving (VPAL -> SNr, abstract) | |
| NDM | NDM.NC.AL.FPC | Lateral Frontopolar Cortex | excitatory-glu | uncertain | Global visual system (FrontalCortex -> BGA, abstract) |
Outbound Region Connections:
| Target Area | Target Region | Target Name | Type | Role | Reference |
| FEC | FEC.FT.SNC.MED | Substantia Nigra Pars Compacta Medial | inhibitory-gaba | uncertain | (unknown reference) |
| FEC.HT.TG.IPD | Interpeduncular Nucleus | inhibitory-gaba | uncertain | (unknown reference) | |
| NMA | NMA.FD.TH.MDL | Lateral Mediodorsal Nucleus of Thalamus | inhibitory-gaba | uncertain | Saccadic Vision (BG -> Thalamus, abstract) |
Thirdparty Circuits
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- Saccadic Vision - see Reference (CP.SACCADIC-VISION)
BG=Basal Ganglia,FEC.FT.BG CN=Caudate Nucleus,FEC.FT.CN (see Basal Ganglia) CR=Cerebellum,LLC.HT.CR (see Cerebellar Complex) FrontalCortex=Anterior Lobe,NC.LOBE.ANT GPe=Globus Pallidus External,FEC.FT.GPE (see Basal Ganglia) LGN=Lateral Geniculate Nucleus,NSA.FD.LGN LIP=Lateral Intraparietal Sulcus,NPE.NC.IPS.LIP RF=Pontine Reticular Formation,HT.RF Retina=Retinal Nucleus,LPC.FD.RT SCi=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon) SCs=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon) SNpr=Substantia Nigra Pars Reticulata Dorsolateral,FEC.FT.SNR.DL STN=Subthalamic Nucleus,FEC.FD.STN (see Subthalamus Area) Thalamus=Thalamus,FD.TH VisualCortex=Occipital Lobe,NC.LOBE.OCC
NACC=Accumbens Nucleus,FEC.FT.ACC (see Basal Ganglia) OMPFC=Orbitofrontal Cortex,NC.AL.OPFC (see Orbitomedial Prefrontal Cortex) SNr=Substantia Nigra Pars Reticulata Medial,FEC.FT.SNR.MED VPAL=Ventral Pallidum,FEC.FT.VP (see Basal Ganglia) VTA=Ventral Tegmental Area,LMC.MM.VTA
References
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