BrainRegionFAM FD MHB

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Medial Habenula

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This page covers biological details of component Medial Habenula. Region is part of aHuman target integrated biological model.

  • Top-down path to region: Forebrain Diencephalon -> Habenula (FAM.FD.HB) -> Medial Habenula (FAM.FD.MHB) (see Mind Maps)
  • Type: nucleus
  • Quality: L0
  • Brain area: Forebrain - Affective Motivations Area (FAM)
  • Area circuit: Reward Emotions Control (FAMXREC)
  • Role: processor.affective
  • Function: Encoding negative feedback, indirect
  • Notes to function:
    • affects VTA, dorsal raphe but via interpeduncular nucleus

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Components

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  • no child items defined

Connectivity

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FAM.FD.MHB.dot.png

Inbound Region Connections:

Source Area Source Region Source Name Type Role Reference
FAM FAM.FT.SEP.BAC Bed Nucleus of Anterior Commissure excitatory-glu uncertain Connectivity map of the habenula (Septum -> M, abstract)
FAM.FT.SEP.DBB Diagonal Band of Broca inhibitory-gaba uncertain Habenula Connections (DBB -> MHb)
FAM.FT.SEP.MED Medial Septal Nucleus modulatory-ach uncertain Both LHb and MHb control the dopaminergic and serotonergic systems (MS -> MHb)
FAM.FT.SEP.SF Septofimbrial Nucleus inhibitory-gaba uncertain Connectivity map of the habenula (Septum -> M, abstract)
FAM.FT.SEP.TR Triangular Septal Nucleus inhibitory-gaba uncertain Connectivity map of the habenula (Septum -> M, abstract)
FEC FEC.FT.ACC.SH Nucleus Accumbens Shell inhibitory-gaba uncertain Connectivity map of the habenula (NAc -> M, abstract)
LMC LMC.HT.LC Locus Coeruleus modulatory-ne uncertain Contribution of nAChR subunits to nicotine withdrawal symptoms (LC -> MHB)

Outbound Region Connections:

Target Area Target Region Target Name Type Role Reference
FAM FAM.FD.LHB.MED Lateral Habenula Medial Part excitatory-glu uncertain Connectivity map of the habenula (M -> L, abstract)
FEC FEC.HT.TG.IPD Interpeduncular Nucleus excitatory-glu uncertain Connectivity map of the habenula (M -> IPN)
TEA TARGET.TEA.ENDOCRINE Endocrine Glands endocrine-pineal-gland (none) Habenula Connections (MHb -> PB)

Thirdparty Circuits

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CPu=Striatum,FEC.FT.ST (see Basal Ganglia)
DBB=Diagonal Band of Broca,FAM.FT.SEP.DBB
DR=Dorsal Raphe Nucleus,LMC.MM.RP.DRN
GPi=Globus Pallidus Internal,FEC.FT.GPI (see Basal Ganglia)
IP=Interpeduncular Nucleus,FEC.HT.TG.IPD
LH=Lateral Hypothalamic Area,LAC.FD.HT.LT (see Hypothalamus)
LHb=Lateral Habenula,FAM.FD.LHB (see Habenula)
LPO=Ventrolateral Preoptic Nucleus,LAC.FD.HT.VLPO
MHb=Medial Habenula,FAM.FD.MHB
MR=Superior Central Raphe Nucleus,LMC.MM.RP.SUC
PB=Endocrine Glands,TARGET.TEA.ENDOCRINE
S=Septal Nuclei,FAM.FT.SEP
SNc=Substantia Nigra Pars Compacta Lateral,FEC.FT.SNC.LT
VTA=Ventral Tegmental Area,LMC.MM.VTA


CPu=Striatum,FEC.FT.ST (see Basal Ganglia)
EP=Endopiriform Nucleus,FAM.FT.EPF
Hippo=Hippocampus,FMM.FT.HC (see Hippocampal Formation)
IPN=Interpeduncular Nucleus,FEC.HT.TG.IPD
L=Lateral Habenula,FAM.FD.LHB (see Habenula)
LH=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN
M=Medial Habenula,FAM.FD.MHB
NAc=Accumbens Nucleus,FEC.FT.ACC (see Basal Ganglia)
PAG=Periaqueductal Gray Matter,LMC.MM.PAG
Raphe=Raphe Nuclei of Medulla,LMC.HL.RP (see Medullary Reticular Formation)
SNc=Substantia Nigra Pars Compacta,FEC.FT.SNC (see Basal Ganglia)
Septum=Septal Nuclei,FAM.FT.SEP
VTA=Ventral Tegmental Area,LMC.MM.VTA


LHb=Lateral Habenula,FAM.FD.LHB (see Habenula)
MHb=Medial Habenula,FAM.FD.MHB


IPN=Interpeduncular Nucleus,FEC.HT.TG.IPD
LC=Locus Coeruleus,LMC.HT.LC
LHB=Lateral Habenula,FAM.FD.LHB (see Habenula)
MHB=Medial Habenula,FAM.FD.MHB


DBB=Diagonal Band of Broca,FAM.FT.SEP.DBB
DRN=Dorsal Raphe Nucleus,LMC.MM.RP.DRN
GPb=Dorsal Pallidum,FEC.FT.DP (see Basal Ganglia)
IPN=Interpeduncular Nucleus,FEC.HT.TG.IPD
LHA=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN
LHbL=Lateral Habenula Lateral Part,FAM.FD.LHB.LT
LHbM=Lateral Habenula Medial Part,FAM.FD.LHB.MED
LPO=Ventrolateral Preoptic Nucleus,LAC.FD.HT.VLPO
LS=Lateral Septal Nucleus,FAM.FT.SEP.LT
MHb=Medial Habenula,FAM.FD.MHB
MRN=Raphe Nuclei of Medulla,LMC.HL.RP (see Medullary Reticular Formation)
MS=Medial Septal Nucleus,FAM.FT.SEP.MED
PS=Posterior Septal Group,FAM.FT.SEP.PG (see Septal Nuclei)
RMTg=Rostromedial Tegmental Nucleus,FEC.HT.TG.RMTG
SNc=Substantia Nigra Pars Compacta,FEC.FT.SNC (see Basal Ganglia)
VP=Ventral Pallidum,FEC.FT.VP (see Basal Ganglia)
VTA=Ventral Tegmental Area,LMC.MM.VTA


IPN=Interpeduncular Nucleus,FEC.HT.TG.IPD
LHb=Lateral Habenula,FAM.FD.LHB (see Habenula)
MHb=Medial Habenula,FAM.FD.MHB


References

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