BrainRegionFEC FT VP VM
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Ventral Pallidum Ventromedial
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This page covers biological details of component Ventral Pallidum Ventromedial. Region is part of aHuman target integrated biological model.
- Top-down path to region: Forebrain Telencephalon -> Basal Ganglia (FEC.FT.BG) -> Globus Pallidus (FEC.FT.GP) -> Ventral Pallidum (FEC.FT.VP) -> Ventral Pallidum Ventromedial (FEC.FT.VP.VM) (see Mind Maps)
- Type: nucleus
- Quality: L0
- Brain area: Forebrain - Execution Control Area (FEC)
- Area circuit: Cognitive Motivational Salience (FECAF)
- Role: basal.ganglia.pallidum
- Function: motivational loop, NAcc-shell
- Notes to function:
- projects to VTA, MD
- circuit - VP-VM-medial, VMPFC, NAcc-medial-shell, MD-rostral-medial
- circuit - VP-VM-lateral, VINS, NAcc-VL, MD-central
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Components
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- no child items defined
Connectivity
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Inbound Region Connections:
| Source Area | Source Region | Source Name | Type | Role | Reference |
| FEC | FEC.FD.STN.DL | Subthalamic Nucleus Dorsolateral | excitatory-glu | uncertain | Functional subdivisions of the subthalamic nucleus (STN -> VP, abstract) |
| FEC.FT.ACC.SH | Nucleus Accumbens Shell | inhibitory-gaba | uncertain | Craving (NACC -> VPAL, abstract) | |
| FEC.FT.IPAC.LT | Lateral Interstitial Anterior Commissural Nucleus | inhibitory-gaba | uncertain | (unknown reference) |
Outbound Region Connections:
| Target Area | Target Region | Target Name | Type | Role | Reference |
| FAM | FAM.FD.LHB.MED | Lateral Habenula Medial Part | inhibitory-gaba | uncertain | Both LHb and MHb control the dopaminergic and serotonergic systems (VP -> LHbM, abstract) |
| FAM.FD.TH.PT | Paratenial Nucleus of Thalamus | inhibitory-gaba | uncertain | Saccadic Vision (BG -> Thalamus, abstract) | |
| FEC | FEC.HT.TG.RMTG | Rostromedial Tegmental Nucleus | inhibitory-gaba | uncertain | (unknown reference) |
| LMC | LMC.HT.TG.PPN | Pedunculopontine Tegmental Nuclei | inhibitory-gaba | uncertain | Combining Novelty, Motivational Salience, and Reward to Control Attention and Learning (VPAL -> PPTG, abstract) |
| LMC.MM.VTA | Ventral Tegmental Area | inhibitory-gaba | uncertain | Craving (VPAL -> VTA, abstract) | |
| NCP | NCP.FD.TH.MDC | Central Mediodorsal Nucleus of Thalamus | inhibitory-gaba | uncertain | Saccadic Vision (BG -> Thalamus, abstract) |
Thirdparty Circuits
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- Combining Novelty, Motivational Salience, and Reward to Control Attention and Learning - see Reference (CT.LONG-TERM-MEMORY-VTA)
ACC=Accumbens Nucleus,FEC.FT.ACC (see Basal Ganglia) CA1=Ventrolateral Cornu Ammonis of Hippocampus,FMM.FT.HC.CA1 (see Hippocampal Formation) CA3=Dorsomedial Cornu Ammonis of Hippocampus,FMM.FT.HC.CA3 (see Hippocampal Formation) DG=Dentate Gyrus,FMM.FT.HC.DG EC=Entorhinal Cortex,FMM.NC.PH.ET (see Rhinal Cortex) PFC=Orbitofrontal Cortex,NC.AL.OPFC (see Orbitomedial Prefrontal Cortex) PPTG=Pedunculopontine Tegmental Nuclei,LMC.HT.TG.PPN SUB=Subiculum,FMM.FT.HF.SUB (see Hippocampal Formation) VPAL=Ventral Pallidum,FEC.FT.VP (see Basal Ganglia) VTA=Ventral Tegmental Area,LMC.MM.VTA
- Saccadic Vision - see Reference (CP.SACCADIC-VISION)
BG=Basal Ganglia,FEC.FT.BG CN=Caudate Nucleus,FEC.FT.CN (see Basal Ganglia) CR=Cerebellum,LLC.HT.CR (see Cerebellar Complex) FrontalCortex=Anterior Lobe,NC.LOBE.ANT GPe=Globus Pallidus External,FEC.FT.GPE (see Basal Ganglia) LGN=Lateral Geniculate Nucleus,NSA.FD.LGN LIP=Lateral Intraparietal Sulcus,NPE.NC.IPS.LIP RF=Pontine Reticular Formation,HT.RF Retina=Retinal Nucleus,LPC.FD.RT SCi=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon) SCs=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon) SNpr=Substantia Nigra Pars Reticulata Dorsolateral,FEC.FT.SNR.DL STN=Subthalamic Nucleus,FEC.FD.STN (see Subthalamus Area) Thalamus=Thalamus,FD.TH VisualCortex=Occipital Lobe,NC.LOBE.OCC
- Both LHb and MHb control the dopaminergic and serotonergic systems - see Reference (CF.HB-DA5HT)
DBB=Diagonal Band of Broca,FAM.FT.SEP.DBB DRN=Dorsal Raphe Nucleus,LMC.MM.RP.DRN GPb=Dorsal Pallidum,FEC.FT.DP (see Basal Ganglia) IPN=Interpeduncular Nucleus,FEC.HT.TG.IPD LHA=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN LHbL=Lateral Habenula Lateral Part,FAM.FD.LHB.LT LHbM=Lateral Habenula Medial Part,FAM.FD.LHB.MED LPO=Ventrolateral Preoptic Nucleus,LAC.FD.HT.VLPO LS=Lateral Septal Nucleus,FAM.FT.SEP.LT MHb=Medial Habenula,FAM.FD.MHB MRN=Raphe Nuclei of Medulla,LMC.HL.RP (see Medullary Reticular Formation) MS=Medial Septal Nucleus,FAM.FT.SEP.MED PS=Posterior Septal Group,FAM.FT.SEP.PG (see Septal Nuclei) RMTg=Rostromedial Tegmental Nucleus,FEC.HT.TG.RMTG SNc=Substantia Nigra Pars Compacta,FEC.FT.SNC (see Basal Ganglia) VP=Ventral Pallidum,FEC.FT.VP (see Basal Ganglia) VTA=Ventral Tegmental Area,LMC.MM.VTA
NACC=Accumbens Nucleus,FEC.FT.ACC (see Basal Ganglia) OMPFC=Orbitofrontal Cortex,NC.AL.OPFC (see Orbitomedial Prefrontal Cortex) SNr=Substantia Nigra Pars Reticulata Medial,FEC.FT.SNR.MED VPAL=Ventral Pallidum,FEC.FT.VP (see Basal Ganglia) VTA=Ventral Tegmental Area,LMC.MM.VTA
References
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