BrainRegionFMM FD MB LMB

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Lateral Mammillary Nucleus

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This page covers biological details of component Lateral Mammillary Nucleus. Region is part of aHuman target integrated biological model.

  • Top-down path to region: Forebrain Diencephalon -> Hypothalamus (FD.HT) -> Mammillary Body (FD.MB) -> Lateral Mammillary Nucleus (FMM.FD.MB.LMB) (see Mind Maps)
  • Type: nucleus
  • Quality: L0
  • Brain area: Forebrain - Memory Management Area (FMM)
  • Area circuit: Orienting Control (MMAORIENT)
  • Role: processor.memory.space
  • Function: Generate theta rythm and relay to HC
  • Notes to function:
    • Memory, recognition, spatial awareness, and interpreting the context of events

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Components

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  • no child items defined

Connectivity

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FMM.FD.MB.LMB.dot.png

Inbound Region Connections:

Source Area Source Region Source Name Type Role Reference
FAM FAM.FT.SEP.MED Medial Septal Nucleus modulatory-ach uncertain Cingulate Gyrus (SEP -> HT, abstract)
FMM FMM.NC.PH.PAS Parasubiculum excitatory-glu uncertain Mammillary bodies: two memory systems in one (PAS -> LMB)
FMM.NC.PH.POS Postsubiculum excitatory-glu uncertain Head Direction Cell Circuit (PSUB -> LMB)
FMM.NC.PH.PRS Presubiculum excitatory-glu uncertain Mammillary bodies: two memory systems in one (PRS -> LMB)
LAC LAC.FD.HT.SUM Supramammillary Nucleus excitatory-glu uncertain Mammillary bodies: two memory systems in one (SupraMM -> LMB)
LMC LMC.HT.TG.LDT Laterodorsal Tegmental Nucleus modulatory-ach uncertain Hippocampal Formation (DTN -> LMam)

Outbound Region Connections:

Target Area Target Region Target Name Type Role Reference
FMM FMM.FD.TH.AD Anterodorsal Nucleus excitatory-glu uncertain Head Direction Cell Circuit (LMB -> AD)
LLC LLC.HT.PRF.RTMG Pontine Reticulotegmental Nucleus excitatory-glu uncertain Mammillary Body (LMB -> RTG)
LMC LMC.HT.TG.LDT Laterodorsal Tegmental Nucleus excitatory-glu uncertain Head Direction Cell Circuit (LMB -> DTN)

Thirdparty Circuits

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AD=Anterodorsal Nucleus,FMM.FD.TH.AD
DTN=Laterodorsal Tegmental Nucleus,LMC.HT.TG.DTG
EC=Entorhinal Cortex,FMM.NC.PH.ET (see Rhinal Cortex)
HC=Hippocampus,FMM.FT.HC (see Hippocampal Formation)
IPD=Interpeduncular Nucleus,FEC.HT.TG.IPD
LD=Lateral Dorsal Nucleus of Thalamus,FMM.FD.TH.LD
LHAB=Habenula,FAM.FD.HB
LMB=Lateral Mammillary Nucleus,FMM.FD.MB.LMB
MVSN=Medial Vestibular Nucleus,LPC.HT.MVBN
NPRP=Prepositus Nucleus,LRC.HL.NPH
PC=Parietal Lobe,NC.LOBE.PAR
PRHC=Postrhinal Cortex,FMM.NC.PH.POR
PSUB=Postsubiculum,FMM.NC.PH.POS
RSP=Retrosplenial Cortex,NCP.NC.MPL.RSC
SUPGEN=Suprageniculate Nucleus of Thalamus,NSA.FD.TH.SG
VC=Occipital Lobe,NC.LOBE.OCC

AN=Anterior Nucleus of Thalamus,FD.TH.AN (see Cognitive Thalamus)
CA1=Ventrolateral Cornu Ammonis of Hippocampus,FMM.FT.HC.CA1 (see Hippocampal Formation)
CA3=Dorsomedial Cornu Ammonis of Hippocampus,FMM.FT.HC.CA3 (see Hippocampal Formation)
DG=Dentate Gyrus,FMM.FT.HC.DG
EC=Entorhinal Cortex,FMM.NC.PH.ET (see Rhinal Cortex)
MBIN=Medial Mammillary Nucleus,FMM.FD.MB.MMB
MBOUT=Lateral Mammillary Nucleus,FMM.FD.MB.LMB
NACC=Accumbens Nucleus,FEC.FT.ACC (see Basal Ganglia)
PERI=Perirhinal Cortex,FMM.NC.PH.PER
PRESUB=Presubiculum,FMM.NC.PH.PRS
SEP=Septal Nuclei,FAM.FT.SEP
SUB=Subiculum,FMM.FT.HF.SUB (see Hippocampal Formation)

ADTH=Anterodorsal Nucleus,FMM.FD.TH.AD
AMTH=Anteromedial Nucleus,NCP.FD.TH.AM
AVTH=Anteroventral Nucleus,FMM.FD.TH.AV
DTN=Laterodorsal Tegmental Nucleus,LMC.HT.TG.LDT
LMB=Lateral Mammillary Nucleus,FMM.FD.MB.LMB
MMB=Medial Mammillary Nucleus,FMM.FD.MB.MMB
MedialEC=Entorhinal Cortex,FMM.NC.PH.ET (see Rhinal Cortex)
PAS=Parasubiculum,FMM.NC.PH.PAS
POS=Postsubiculum,FMM.NC.PH.POS
PRS=Presubiculum,FMM.NC.PH.PRS
SEP=Septal Nuclei,FAM.FT.SEP
SUB=Subiculum,FMM.FT.HF.SUB (see Hippocampal Formation)
SupraMM=Supramammillary Nucleus,LAC.FD.HT.SUM
TuberoMM=Lateral Tuberal Nuclei,LAC.FD.HT.LTUB (see Hypothalamus)
VTN=Ventral Tegmental Area,LMC.MM.VTA

LMB=Lateral Mammillary Nucleus,FMM.FD.MB.LMB
MMB=Medial Mammillary Nucleus,FMM.FD.MB.MMB
RTG=Pontine Reticulotegmental Nucleus,LLC.HT.PRF.RTMG

ATN=Anterior Nucleus of Thalamus,FD.TH.AN (see Cognitive Thalamus)
CA1=Ventrolateral Cornu Ammonis of Hippocampus,FMM.FT.HC.CA1 (see Hippocampal Formation)
CA3=Dorsomedial Cornu Ammonis of Hippocampus,FMM.FT.HC.CA3 (see Hippocampal Formation)
DG=Dentate Gyrus,FMM.FT.HC.DG
DTN=Laterodorsal Tegmental Nucleus,LMC.HT.TG.LDT
EC=Entorhinal Cortex,FMM.NC.PH.ET (see Rhinal Cortex)
LDN=Lateral Dorsal Nucleus of Thalamus,FMM.FD.TH.LD
LMam=Lateral Mammillary Nucleus,FMM.FD.MB.LMB
PoS=Postsubiculum,FMM.NC.PH.POS
Rsp=Retrosplenial Cortex,NCP.NC.MPL.RSC
Sub=Subiculum,FMM.FT.HF.SUB (see Hippocampal Formation)


References

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