Difference between revisions of "BrainAreaLMC"

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| '''ID''' || '''Name''' || '''Regions'''
 
| '''ID''' || '''Name''' || '''Regions'''
 
|-
 
|-
−
| 5HT || Serotonin - Feelings of Well-Being and Happiness || [[BrainRegionLMC_HM_RP_MG|LMC.HM.RP.MG]], [[BrainRegionLMC_HM_RP_OB|LMC.HM.RP.OB]], [[BrainRegionLMC_HM_RP_PL|LMC.HM.RP.PL]], [[BrainRegionLMC_HP_RP_LI|LMC.HP.RP.LI]], [[BrainRegionLMC_HP_RP_PRN|LMC.HP.RP.PRN]], [[BrainRegionLMC_MM_RF_SUC|LMC.MM.RF.SUC]], [[BrainRegionLMC_MM_RP_DRN|LMC.MM.RP.DRN]]
+
| 5HT || Serotonin - Feelings of Well-Being and Happiness || [[BrainRegionLMC_HL_RP_MG|LMC.HL.RP.MG]], [[BrainRegionLMC_HL_RP_OB|LMC.HL.RP.OB]], [[BrainRegionLMC_HL_RP_PL|LMC.HL.RP.PL]], [[BrainRegionLMC_HP_RP_LI|LMC.HP.RP.LI]], [[BrainRegionLMC_HP_RP_PRN|LMC.HP.RP.PRN]], [[BrainRegionLMC_MM_RF_SUC|LMC.MM.RF.SUC]], [[BrainRegionLMC_MM_RP_DRN|LMC.MM.RP.DRN]]
 
|-
 
|-
−
| ACH || Acetylcholine - PNS Actions and CNS plasticity, arousal and reward || [[BrainRegionLMC_FT_NBM|LMC.FT.NBM]], [[BrainRegionLMC_HP_TG_DTG|LMC.HP.TG.DTG]], [[BrainRegionLMC_HP_TG_LDT|LMC.HP.TG.LDT]], [[BrainRegionLMC_HP_TG_VTG|LMC.HP.TG.VTG]]
+
| ACH || Acetylcholine - PNS Actions and CNS plasticity, arousal and reward || [[BrainRegionLMC_FT_NBM|LMC.FT.NBM]], [[BrainRegionLMC_HT_TG_DTG|LMC.HT.TG.DTG]], [[BrainRegionLMC_HT_TG_LDT|LMC.HT.TG.LDT]], [[BrainRegionLMC_HT_TG_VTG|LMC.HT.TG.VTG]]
 
|-
 
|-
 
| DA || Dopamine - Reward-Motivated Behavior, Cognitive Alertness || [[BrainRegionLMC_MM_VTA|LMC.MM.VTA]]
 
| DA || Dopamine - Reward-Motivated Behavior, Cognitive Alertness || [[BrainRegionLMC_MM_VTA|LMC.MM.VTA]]
Line 20: Line 20:
 
| ENK || Enkephalin -  Regulating Nociception in Body || [[BrainRegionLMC_MM_PAG|LMC.MM.PAG]]
 
| ENK || Enkephalin -  Regulating Nociception in Body || [[BrainRegionLMC_MM_PAG|LMC.MM.PAG]]
 
|-
 
|-
−
| NE || Norepinephrine - Vigilant Concentration, Stress Hormone, Fight-or-Flight Response || [[BrainRegionLMC_HP_LC|LMC.HP.LC]]
+
| NE || Norepinephrine - Vigilant Concentration, Stress Hormone, Fight-or-Flight Response || [[BrainRegionLMC_HT_LC|LMC.HT.LC]]
 
|}
 
|}
  
Line 31: Line 31:
 
| '''Component ID''' || '''Component Name''' || '''Type''' || '''Service''' || '''Function''' || '''Comments'''
 
| '''Component ID''' || '''Component Name''' || '''Type''' || '''Service''' || '''Function''' || '''Comments'''
 
|-
 
|-
−
| [[BrainRegionLMC_HM_RP_MG|LMC.HM.RP.MG]] || Raphe Magnus Nucleus || nucleus || LUS || Inhubit head and spinal pain || B3, contacts with enkephalenic neurons in<BR>substantia gelatinosa
+
| [[BrainRegionLMC_HL_RP_MG|LMC.HL.RP.MG]] || Raphe Magnus Nucleus || nucleus || LUS || Inhubit head and spinal pain || B3, contacts with enkephalenic neurons in<BR>substantia gelatinosa
 
|-
 
|-
−
| [[BrainRegionLMC_HM_RP_OB|LMC.HM.RP.OB]] || Raphe Obscurus Nucleus || nucleus || LUS || Regulate cardiovascular function via sympathetic spinal column || B2
+
| [[BrainRegionLMC_HL_RP_OB|LMC.HL.RP.OB]] || Raphe Obscurus Nucleus || nucleus || LUS || Regulate cardiovascular function via sympathetic spinal column || B2
 
|-
 
|-
−
| [[BrainRegionLMC_HM_RP_PL|LMC.HM.RP.PL]] || Raphe Pallidus Nucleus || nucleus || LUS || Spinal pain control || B1
+
| [[BrainRegionLMC_HL_RP_PL|LMC.HL.RP.PL]] || Raphe Pallidus Nucleus || nucleus || LUS || Spinal pain control || B1
 
|-
 
|-
 
| [[BrainRegionLMC_HP_RP_LI|LMC.HP.RP.LI]] || Raphe Nucleus Linearis || nucleus || LUS || Release of 5-HT was only obtained on stimulation of this nucleus || B8, Does not project to CR, but to forebrain, to<BR>dorsal raphe nucleus (lies above DRN); dendrites to<BR>vascular plexus, maybe sensing blood pressure
 
| [[BrainRegionLMC_HP_RP_LI|LMC.HP.RP.LI]] || Raphe Nucleus Linearis || nucleus || LUS || Release of 5-HT was only obtained on stimulation of this nucleus || B8, Does not project to CR, but to forebrain, to<BR>dorsal raphe nucleus (lies above DRN); dendrites to<BR>vascular plexus, maybe sensing blood pressure
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|  || [[BrainRegionLMC_MM_RP_DRN|LMC.MM.RP.DRN]] || [[BrainRegionFAM_FD_LHB_MED|FAM.FD.LHB.MED]] || Lateral Habenula Medial Part || nucleus-nucleus || [http://www.scholarpedia.org/article/Habenula Habenula Connections (LHb -> DR, abstract)]
 
|  || [[BrainRegionLMC_MM_RP_DRN|LMC.MM.RP.DRN]] || [[BrainRegionFAM_FD_LHB_MED|FAM.FD.LHB.MED]] || Lateral Habenula Medial Part || nucleus-nucleus || [http://www.scholarpedia.org/article/Habenula Habenula Connections (LHb -> DR, abstract)]
 
|-
 
|-
−
| [[BrainAreaLAC|LAC]] || [[BrainRegionLMC_HM_RP_MG|LMC.HM.RP.MG]] || [[BrainRegionLAC_FD_HT_LTN|LAC.FD.HT.LTN]] || Lateral Hypothalamic Nucleus || nucleus-nucleus || (unknown reference)
+
| [[BrainAreaLAC|LAC]] || [[BrainRegionLMC_HL_RP_MG|LMC.HL.RP.MG]] || [[BrainRegionLAC_FD_HT_LTN|LAC.FD.HT.LTN]] || Lateral Hypothalamic Nucleus || nucleus-nucleus || (unknown reference)
 
|-
 
|-
 
|  ||  || [[BrainRegionLAC_FD_HT_PV|LAC.FD.HT.PV]] || Paraventricular Nucleus || nucleus-nucleus || (unknown reference)
 
|  ||  || [[BrainRegionLAC_FD_HT_PV|LAC.FD.HT.PV]] || Paraventricular Nucleus || nucleus-nucleus || (unknown reference)
 
|-
 
|-
−
|  || [[BrainRegionLMC_HM_RP_OB|LMC.HM.RP.OB]] || [[BrainRegionLAC_FD_HT_PO|LAC.FD.HT.PO]] || Preoptic Nucleus || nucleus-nucleus || (unknown reference)
+
|  || [[BrainRegionLMC_HL_RP_OB|LMC.HL.RP.OB]] || [[BrainRegionLAC_FD_HT_PO|LAC.FD.HT.PO]] || Preoptic Nucleus || nucleus-nucleus || (unknown reference)
 
|-
 
|-
−
| [[BrainAreaLLC|LLC]] || [[BrainRegionLMC_HM_RP_MG|LMC.HM.RP.MG]] || [[BrainRegionLLC_MM_SCNF|LLC.MM.SCNF]] || Subcuneiform Nucleus || nucleus-nucleus || (unknown reference)
+
| [[BrainAreaLLC|LLC]] || [[BrainRegionLMC_HL_RP_MG|LMC.HL.RP.MG]] || [[BrainRegionLLC_MM_SCNF|LLC.MM.SCNF]] || Subcuneiform Nucleus || nucleus-nucleus || (unknown reference)
 
|-
 
|-
 
|  || [[BrainRegionLMC_HP_RP_PRN|LMC.HP.RP.PRN]] || [[BrainRegionLLC_MM_SCNF|LLC.MM.SCNF]] || Subcuneiform Nucleus || nucleus-nucleus || (unknown reference)
 
|  || [[BrainRegionLMC_HP_RP_PRN|LMC.HP.RP.PRN]] || [[BrainRegionLLC_MM_SCNF|LLC.MM.SCNF]] || Subcuneiform Nucleus || nucleus-nucleus || (unknown reference)
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|  || [[BrainRegionLMC_MM_RP_DRN|LMC.MM.RP.DRN]] || [[BrainRegionLLC_FD_TH_SF|LLC.FD.TH.SF]] || Subfascicular Nucleus of Thalamus || nucleus-nucleus-gaba || (unknown reference)
 
|  || [[BrainRegionLMC_MM_RP_DRN|LMC.MM.RP.DRN]] || [[BrainRegionLLC_FD_TH_SF|LLC.FD.TH.SF]] || Subfascicular Nucleus of Thalamus || nucleus-nucleus-gaba || (unknown reference)
 
|-
 
|-
−
| [[BrainAreaLMC|LMC]] || [[BrainRegionLMC_HM_RP_MG|LMC.HM.RP.MG]] || [[BrainRegionLMC_MM_PAG|LMC.MM.PAG]] || Periaqueductal Gray Matter || nucleus-nucleus-ENK || (unknown reference)
+
| [[BrainAreaLMC|LMC]] || [[BrainRegionLMC_HL_RP_MG|LMC.HL.RP.MG]] || [[BrainRegionLMC_MM_PAG|LMC.MM.PAG]] || Periaqueductal Gray Matter || nucleus-nucleus-ENK || (unknown reference)
 
|-
 
|-
−
|  || [[BrainRegionLMC_HM_RP_PL|LMC.HM.RP.PL]] || [[BrainRegionLMC_MM_PAG|LMC.MM.PAG]] || Periaqueductal Gray Matter || nucleus-nucleus-ENK || (unknown reference)
+
|  || [[BrainRegionLMC_HL_RP_PL|LMC.HL.RP.PL]] || [[BrainRegionLMC_MM_PAG|LMC.MM.PAG]] || Periaqueductal Gray Matter || nucleus-nucleus-ENK || (unknown reference)
 
|}
 
|}
  
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|  ||  || [[BrainRegionLAC_FD_HT_SUM|LAC.FD.HT.SUM]] || Supramammillary Nucleus || nucleus-nucleus-5HT || (unknown reference)
 
|  ||  || [[BrainRegionLAC_FD_HT_SUM|LAC.FD.HT.SUM]] || Supramammillary Nucleus || nucleus-nucleus-5HT || (unknown reference)
 
|-
 
|-
−
| [[BrainAreaLLC|LLC]] || [[BrainRegionLMC_HM_RP_OB|LMC.HM.RP.OB]] || [[BrainRegionLLC_HP_CR_SC|LLC.HP.CR.SC]] || Spinocerebellum || nucleus-allocortex-5HT || (unknown reference)
+
| [[BrainAreaLLC|LLC]] || [[BrainRegionLMC_HL_RP_OB|LMC.HL.RP.OB]] || [[BrainRegionLLC_HT_CR_SC|LLC.HT.CR.SC]] || Spinocerebellum || nucleus-allocortex-5HT || (unknown reference)
 
|-
 
|-
−
|  || [[BrainRegionLMC_HP_RP_PRN|LMC.HP.RP.PRN]] || [[BrainRegionLLC_HP_CR_SC|LLC.HP.CR.SC]] || Spinocerebellum || nucleus-allocortex-5HT || (unknown reference)
+
|  || [[BrainRegionLMC_HP_RP_PRN|LMC.HP.RP.PRN]] || [[BrainRegionLLC_HT_CR_SC|LLC.HT.CR.SC]] || Spinocerebellum || nucleus-allocortex-5HT || (unknown reference)
 
|-
 
|-
−
| [[BrainAreaLPC|LPC]] || [[BrainRegionLMC_HM_RP_MG|LMC.HM.RP.MG]] || [[BrainRegionLPC_SC_PH_LSG|LPC.SC.PH.LSG]] || Lower Substantia Gelatinosa || nucleus-nucleus-5HT || (unknown reference)
+
| [[BrainAreaLPC|LPC]] || [[BrainRegionLMC_HL_RP_MG|LMC.HL.RP.MG]] || [[BrainRegionLPC_SC_PH_LSG|LPC.SC.PH.LSG]] || Lower Substantia Gelatinosa || nucleus-nucleus-5HT || (unknown reference)
 
|-
 
|-
 
|  ||  || [[BrainRegionLPC_SC_PH_USG|LPC.SC.PH.USG]] || Upper Substantia Gelatinosa || nucleus-nucleus-5HT || (unknown reference)
 
|  ||  || [[BrainRegionLPC_SC_PH_USG|LPC.SC.PH.USG]] || Upper Substantia Gelatinosa || nucleus-nucleus-5HT || (unknown reference)
 
|-
 
|-
−
|  || [[BrainRegionLMC_HM_RP_OB|LMC.HM.RP.OB]] || [[BrainRegionLPC_SC_IZ_IMM|LPC.SC.IZ.IMM]] || Intermediomedial Nucleus || nucleus-nucleus-5HT || (unknown reference)
+
|  || [[BrainRegionLMC_HL_RP_OB|LMC.HL.RP.OB]] || [[BrainRegionLPC_SC_IZ_IMM|LPC.SC.IZ.IMM]] || Intermediomedial Nucleus || nucleus-nucleus-5HT || (unknown reference)
 
|-
 
|-
−
|  || [[BrainRegionLMC_HM_RP_PL|LMC.HM.RP.PL]] || [[BrainRegionLPC_SC_PH_LMG|LPC.SC.PH.LMG]] || Lower Marginal Nucleus || nucleus-nucleus-5HT || (unknown reference)
+
|  || [[BrainRegionLMC_HL_RP_PL|LMC.HL.RP.PL]] || [[BrainRegionLPC_SC_PH_LMG|LPC.SC.PH.LMG]] || Lower Marginal Nucleus || nucleus-nucleus-5HT || (unknown reference)
 
|-
 
|-
 
|  ||  || [[BrainRegionLPC_SC_PH_UMG|LPC.SC.PH.UMG]] || Upper Marginal Nucleus || nucleus-nucleus-5HT || (unknown reference)
 
|  ||  || [[BrainRegionLPC_SC_PH_UMG|LPC.SC.PH.UMG]] || Upper Marginal Nucleus || nucleus-nucleus-5HT || (unknown reference)
Line 128: Line 128:
 
| [[BrainRegionLMC_FT_NBM|LMC.FT.NBM]] || Basal Nucleus of Meynert || nucleus || FAU || Control imagination vs perception || ACh source, attention; modulatory nucleus
 
| [[BrainRegionLMC_FT_NBM|LMC.FT.NBM]] || Basal Nucleus of Meynert || nucleus || FAU || Control imagination vs perception || ACh source, attention; modulatory nucleus
 
|-
 
|-
−
| [[BrainRegionLMC_HP_TG_DTG|LMC.HP.TG.DTG]] || Dorsal Tegmental Nucleus || nucleus || LUS || accurate landmark navigation || vestibular sensory information to mammllary bodies<BR>for orientation
+
| [[BrainRegionLMC_HT_TG_DTG|LMC.HT.TG.DTG]] || Dorsal Tegmental Nucleus || nucleus || LUS || accurate landmark navigation || vestibular sensory information to mammllary bodies<BR>for orientation
 
|-
 
|-
−
| [[BrainRegionLMC_HP_TG_LDT|LMC.HP.TG.LDT]] || Laterodorsal Tegmental Nucleus || nucleus || LUS || Modulating sustained attention or in mediating alerting responses || sleep, waking, motor function, learning and reward
+
| [[BrainRegionLMC_HT_TG_LDT|LMC.HT.TG.LDT]] || Laterodorsal Tegmental Nucleus || nucleus || LUS || Modulating sustained attention or in mediating alerting responses || sleep, waking, motor function, learning and reward
 
|-
 
|-
−
| [[BrainRegionLMC_HP_TG_VTG|LMC.HP.TG.VTG]] || Ventral Tegmental Nucleus || nucleus || LUS || moderates hippocampal-driven rhythmic firing frequency in medial mammillary || contribute to episodic memory and new learning in<BR>humans as well as spatial memory
+
| [[BrainRegionLMC_HT_TG_VTG|LMC.HT.TG.VTG]] || Ventral Tegmental Nucleus || nucleus || LUS || moderates hippocampal-driven rhythmic firing frequency in medial mammillary || contribute to episodic memory and new learning in<BR>humans as well as spatial memory
 
|}
 
|}
  
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| <font color="red">Cortical</font> || || || || ||
 
| <font color="red">Cortical</font> || || || || ||
 
|-
 
|-
−
| [[BrainAreaNSA|NSA]] || [[BrainRegionLMC_HP_TG_LDT|LMC.HP.TG.LDT]] || [[BrainRegionNSA_FD_TH_SG|NSA.FD.TH.SG]] || Suprageniculate Nucleus of Thalamus || nucleus-nucleus || [http://www.scholarpedia.org/article/Head_direction_cells Head Direction Cell Circuit (SUPGEN -> DTN)]
+
| [[BrainAreaNSA|NSA]] || [[BrainRegionLMC_HT_TG_LDT|LMC.HT.TG.LDT]] || [[BrainRegionNSA_FD_TH_SG|NSA.FD.TH.SG]] || Suprageniculate Nucleus of Thalamus || nucleus-nucleus || [http://www.scholarpedia.org/article/Head_direction_cells Head Direction Cell Circuit (SUPGEN -> DTN)]
 
|-
 
|-
 
| <font color="red">Subcortical</font> || || || || ||
 
| <font color="red">Subcortical</font> || || || || ||
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|  ||  || [[BrainRegionFAM_FT_BNST|FAM.FT.BNST]] || Bed Nucleus of Stria Terminalis || nucleus-nucleus || (unknown reference)
 
|  ||  || [[BrainRegionFAM_FT_BNST|FAM.FT.BNST]] || Bed Nucleus of Stria Terminalis || nucleus-nucleus || (unknown reference)
 
|-
 
|-
−
|  || [[BrainRegionLMC_HP_TG_DTG|LMC.HP.TG.DTG]] || [[BrainRegionFAM_FD_LHB_MED|FAM.FD.LHB.MED]] || Lateral Habenula Medial Part || nucleus-nucleus || (unknown reference)
+
|  || [[BrainRegionLMC_HT_TG_DTG|LMC.HT.TG.DTG]] || [[BrainRegionFAM_FD_LHB_MED|FAM.FD.LHB.MED]] || Lateral Habenula Medial Part || nucleus-nucleus || (unknown reference)
 
|-
 
|-
−
|  || [[BrainRegionLMC_HP_TG_LDT|LMC.HP.TG.LDT]] || [[BrainRegionFAM_HP_PPN_RMTG|FAM.HP.PPN.RMTG]] || Rostromedial Tegmental Nucleus || nucleus-nucleus-gaba || (unknown reference)
+
|  || [[BrainRegionLMC_HT_TG_VTG|LMC.HT.TG.VTG]] || [[BrainRegionFAM_FD_LHB_MED|FAM.FD.LHB.MED]] || Lateral Habenula Medial Part || nucleus-nucleus || (unknown reference)
−
|-
+
−
|  || [[BrainRegionLMC_HP_TG_VTG|LMC.HP.TG.VTG]] || [[BrainRegionFAM_FD_LHB_MED|FAM.FD.LHB.MED]] || Lateral Habenula Medial Part || nucleus-nucleus || (unknown reference)
+
 
|-
 
|-
 
| [[BrainAreaFEC|FEC]] || [[BrainRegionLMC_FT_NBM|LMC.FT.NBM]] || [[BrainRegionFEC_FD_STN_CD|FEC.FD.STN.CD]] || Subthalamic Nucleus Caudal || nucleus-nucleus || (unknown reference)
 
| [[BrainAreaFEC|FEC]] || [[BrainRegionLMC_FT_NBM|LMC.FT.NBM]] || [[BrainRegionFEC_FD_STN_CD|FEC.FD.STN.CD]] || Subthalamic Nucleus Caudal || nucleus-nucleus || (unknown reference)
Line 167: Line 165:
 
|  ||  || [[BrainRegionFEC_FT_ACC_SH|FEC.FT.ACC.SH]] || Nucleus Accumbens Shell || nucleus-nucleus-gaba || [http://www.expertsmind.com/topic/emotion/affective-basal-ganglia-circuit-93570.aspx Affective basal ganglia circuit (NACC -> nBM, abstract)]
 
|  ||  || [[BrainRegionFEC_FT_ACC_SH|FEC.FT.ACC.SH]] || Nucleus Accumbens Shell || nucleus-nucleus-gaba || [http://www.expertsmind.com/topic/emotion/affective-basal-ganglia-circuit-93570.aspx Affective basal ganglia circuit (NACC -> nBM, abstract)]
 
|-
 
|-
−
| [[BrainAreaFMM|FMM]] || [[BrainRegionLMC_HP_TG_LDT|LMC.HP.TG.LDT]] || [[BrainRegionFMM_FD_MB_LMB|FMM.FD.MB.LMB]] || Lateral Mammillary Nucleus || nucleus-nucleus || [http://www.scholarpedia.org/article/Head_direction_cells Head Direction Cell Circuit (LMB -> DTN)]
+
|  || [[BrainRegionLMC_HT_TG_LDT|LMC.HT.TG.LDT]] || [[BrainRegionFEC_HT_PPN_RMTG|FEC.HT.PPN.RMTG]] || Rostromedial Tegmental Nucleus || nucleus-nucleus-gaba || (unknown reference)
 +
|-
 +
| [[BrainAreaFMM|FMM]] || [[BrainRegionLMC_HT_TG_LDT|LMC.HT.TG.LDT]] || [[BrainRegionFMM_FD_MB_LMB|FMM.FD.MB.LMB]] || Lateral Mammillary Nucleus || nucleus-nucleus || [http://www.scholarpedia.org/article/Head_direction_cells Head Direction Cell Circuit (LMB -> DTN)]
 
|-
 
|-
−
| [[BrainAreaLRC|LRC]] || [[BrainRegionLMC_HP_TG_DTG|LMC.HP.TG.DTG]] || [[BrainRegionLRC_HM_NPH|LRC.HM.NPH]] || Prepositus Nucleus || nucleus-nucleus || (unknown reference)
+
| [[BrainAreaLRC|LRC]] || [[BrainRegionLMC_HT_TG_DTG|LMC.HT.TG.DTG]] || [[BrainRegionLRC_HL_NPH|LRC.HL.NPH]] || Prepositus Nucleus || nucleus-nucleus || (unknown reference)
 
|}
 
|}
  
Line 187: Line 187:
 
| [[BrainAreaFAM|FAM]] || [[BrainRegionLMC_FT_NBM|LMC.FT.NBM]] || [[BrainRegionFAM_FT_AM_BM|FAM.FT.AM.BM]] || Magnocellular Basal Amygdaloid Nucleus || nucleus-nucleus-ACh || (unknown reference)
 
| [[BrainAreaFAM|FAM]] || [[BrainRegionLMC_FT_NBM|LMC.FT.NBM]] || [[BrainRegionFAM_FT_AM_BM|FAM.FT.AM.BM]] || Magnocellular Basal Amygdaloid Nucleus || nucleus-nucleus-ACh || (unknown reference)
 
|-
 
|-
−
| || [[BrainRegionLMC_HP_TG_LDT|LMC.HP.TG.LDT]] || [[BrainRegionFAM_HP_PPN_IPD|FAM.HP.PPN.IPD]] || Interpeduncular Nucleus || nucleus-nucleus-ACh || [http://www.scholarpedia.org/article/Head_direction_cells Head Direction Cell Circuit (DTN -> IPD)]
+
| [[BrainAreaFEC|FEC]] || [[BrainRegionLMC_HT_TG_LDT|LMC.HT.TG.LDT]] || [[BrainRegionFEC_HT_PPN_IPD|FEC.HT.PPN.IPD]] || Interpeduncular Nucleus || nucleus-nucleus-ACh || [http://www.scholarpedia.org/article/Head_direction_cells Head Direction Cell Circuit (DTN -> IPD)]
 
|-
 
|-
−
| [[BrainAreaFMM|FMM]] || [[BrainRegionLMC_HP_TG_DTG|LMC.HP.TG.DTG]] || [[BrainRegionFMM_FD_MB_LMB|FMM.FD.MB.LMB]] || Lateral Mammillary Nucleus || nucleus-nucleus-ACh || (unknown reference)
+
| [[BrainAreaFMM|FMM]] || [[BrainRegionLMC_HT_TG_DTG|LMC.HT.TG.DTG]] || [[BrainRegionFMM_FD_MB_LMB|FMM.FD.MB.LMB]] || Lateral Mammillary Nucleus || nucleus-nucleus-ACh || (unknown reference)
 
|-
 
|-
−
|  || [[BrainRegionLMC_HP_TG_VTG|LMC.HP.TG.VTG]] || [[BrainRegionFMM_FD_MB_MMB|FMM.FD.MB.MMB]] || Medial Mammillary Nucleus || nucleus-nucleus || (unknown reference)
+
|  || [[BrainRegionLMC_HT_TG_VTG|LMC.HT.TG.VTG]] || [[BrainRegionFMM_FD_MB_MMB|FMM.FD.MB.MMB]] || Medial Mammillary Nucleus || nucleus-nucleus || (unknown reference)
 
|-
 
|-
−
| [[BrainAreaLAC|LAC]] || [[BrainRegionLMC_HP_TG_LDT|LMC.HP.TG.LDT]] || [[BrainRegionLAC_HM_SAL_ISL|LAC.HM.SAL.ISL]] || Inferior Salivatory Nucleus || nucleus-nucleus-ACh || (unknown reference)
+
| [[BrainAreaLAC|LAC]] || [[BrainRegionLMC_HT_TG_LDT|LMC.HT.TG.LDT]] || [[BrainRegionLAC_HL_SAL_ISL|LAC.HL.SAL.ISL]] || Inferior Salivatory Nucleus || nucleus-nucleus-ACh || (unknown reference)
 
|-
 
|-
−
|  ||  || [[BrainRegionLAC_HM_SAL_SSL|LAC.HM.SAL.SSL]] || Superior Salivatory Nucleus || nucleus-nucleus-ACh || (unknown reference)
+
|  ||  || [[BrainRegionLAC_HL_SAL_SSL|LAC.HL.SAL.SSL]] || Superior Salivatory Nucleus || nucleus-nucleus-ACh || (unknown reference)
 
|-
 
|-
−
| [[BrainAreaLMC|LMC]] || [[BrainRegionLMC_HP_TG_VTG|LMC.HP.TG.VTG]] || [[BrainRegionLMC_MM_VTA|LMC.MM.VTA]] || Ventral Tegmental Area || nucleus-nucleus || (unknown reference)
+
| [[BrainAreaLMC|LMC]] || [[BrainRegionLMC_HT_TG_VTG|LMC.HT.TG.VTG]] || [[BrainRegionLMC_MM_VTA|LMC.MM.VTA]] || Ventral Tegmental Area || nucleus-nucleus || (unknown reference)
 
|-
 
|-
−
| [[BrainAreaLRC|LRC]] || [[BrainRegionLMC_HP_TG_LDT|LMC.HP.TG.LDT]] || [[BrainRegionLRC_HM_NPH|LRC.HM.NPH]] || Prepositus Nucleus || nucleus-nucleus-ACh || [http://www.scholarpedia.org/article/Head_direction_cells Head Direction Cell Circuit (DTN -> NPRP)]
+
| [[BrainAreaLRC|LRC]] || [[BrainRegionLMC_HT_TG_LDT|LMC.HT.TG.LDT]] || [[BrainRegionLRC_HL_NPH|LRC.HL.NPH]] || Prepositus Nucleus || nucleus-nucleus-ACh || [http://www.scholarpedia.org/article/Head_direction_cells Head Direction Cell Circuit (DTN -> NPRP)]
 
|}
 
|}
  
Line 224: Line 224:
 
|-
 
|-
 
| [[BrainAreaFAM|FAM]] || [[BrainRegionLMC_MM_VTA|LMC.MM.VTA]] || [[BrainRegionFAM_FT_BNST|FAM.FT.BNST]] || Bed Nucleus of Stria Terminalis || nucleus-nucleus || (unknown reference)
 
| [[BrainAreaFAM|FAM]] || [[BrainRegionLMC_MM_VTA|LMC.MM.VTA]] || [[BrainRegionFAM_FT_BNST|FAM.FT.BNST]] || Bed Nucleus of Stria Terminalis || nucleus-nucleus || (unknown reference)
−
|-
 
−
|  ||  || [[BrainRegionFAM_HP_PPN_RMTG|FAM.HP.PPN.RMTG]] || Rostromedial Tegmental Nucleus || nucleus-nucleus-gaba || [http://www.surgicalneurologyint.com/article.asp?issn=2152-7806;year=2012;volume=3;issue=2;spage=40;epage=46;aulast=Langevin Amygdala and its network (RMTG -> VTA)]
 
 
|-
 
|-
 
| [[BrainAreaFEC|FEC]] || [[BrainRegionLMC_MM_VTA|LMC.MM.VTA]] || [[BrainRegionFEC_FT_ACC_CORE|FEC.FT.ACC.CORE]] || Nucleus Accumbens Core || nucleus-nucleus-gaba || [http://neurowiki2012.wikispaces.com/Presynaptic+Mechanisms+of+Synaptic+Plasticity Reward circuit of human brain (NACC -> VTA, abstract)]
 
| [[BrainAreaFEC|FEC]] || [[BrainRegionLMC_MM_VTA|LMC.MM.VTA]] || [[BrainRegionFEC_FT_ACC_CORE|FEC.FT.ACC.CORE]] || Nucleus Accumbens Core || nucleus-nucleus-gaba || [http://neurowiki2012.wikispaces.com/Presynaptic+Mechanisms+of+Synaptic+Plasticity Reward circuit of human brain (NACC -> VTA, abstract)]
Line 231: Line 229:
 
|  ||  || [[BrainRegionFEC_FT_VP_VM|FEC.FT.VP.VM]] || Ventral Pallidum Ventromedial || nucleus-nucleus-gaba || [http://www.impulsecontroldisorders.org/html/cravings.html Craving (VPAL -> VTA, abstract)]
 
|  ||  || [[BrainRegionFEC_FT_VP_VM|FEC.FT.VP.VM]] || Ventral Pallidum Ventromedial || nucleus-nucleus-gaba || [http://www.impulsecontroldisorders.org/html/cravings.html Craving (VPAL -> VTA, abstract)]
 
|-
 
|-
−
| [[BrainAreaLMC|LMC]] || [[BrainRegionLMC_MM_VTA|LMC.MM.VTA]] || [[BrainRegionLMC_HP_TG_VTG|LMC.HP.TG.VTG]] || Ventral Tegmental Nucleus || nucleus-nucleus || (unknown reference)
+
|  ||  || [[BrainRegionFEC_HT_PPN_RMTG|FEC.HT.PPN.RMTG]] || Rostromedial Tegmental Nucleus || nucleus-nucleus-gaba || [http://www.surgicalneurologyint.com/article.asp?issn=2152-7806;year=2012;volume=3;issue=2;spage=40;epage=46;aulast=Langevin Amygdala and its network (RMTG -> VTA)]
 +
|-
 +
| [[BrainAreaLMC|LMC]] || [[BrainRegionLMC_MM_VTA|LMC.MM.VTA]] || [[BrainRegionLMC_HT_TG_VTG|LMC.HT.TG.VTG]] || Ventral Tegmental Nucleus || nucleus-nucleus || (unknown reference)
 
|}
 
|}
  
Line 301: Line 301:
 
| <font color="red">Subcortical</font> || || || || ||
 
| <font color="red">Subcortical</font> || || || || ||
 
|-
 
|-
−
| [[BrainAreaLAC|LAC]] || [[BrainRegionLMC_MM_PAG|LMC.MM.PAG]] || [[BrainRegionLAC_HP_BR|LAC.HP.BR]] || Barrington's Nucleus || nucleus-nucleus-ENK || [http://jp.physoc.org/content/557/1/287/F9.expansion.html Schematic overview of spinobulbospinal micturition reflex pathway (PAG -> BAR)]
+
| [[BrainAreaLAC|LAC]] || [[BrainRegionLMC_MM_PAG|LMC.MM.PAG]] || [[BrainRegionLAC_HT_BR|LAC.HT.BR]] || Barrington's Nucleus || nucleus-nucleus-ENK || [http://jp.physoc.org/content/557/1/287/F9.expansion.html Schematic overview of spinobulbospinal micturition reflex pathway (PAG -> BAR)]
 
|-
 
|-
 
| [[BrainAreaLLC|LLC]] || [[BrainRegionLMC_MM_PAG|LMC.MM.PAG]] || [[BrainRegionLLC_FD_TH_SF|LLC.FD.TH.SF]] || Subfascicular Nucleus of Thalamus || nucleus-nucleus-ENK || (unknown reference)
 
| [[BrainAreaLLC|LLC]] || [[BrainRegionLMC_MM_PAG|LMC.MM.PAG]] || [[BrainRegionLLC_FD_TH_SF|LLC.FD.TH.SF]] || Subfascicular Nucleus of Thalamus || nucleus-nucleus-ENK || (unknown reference)
 
|-
 
|-
−
| [[BrainAreaLMC|LMC]] || [[BrainRegionLMC_MM_PAG|LMC.MM.PAG]] || [[BrainRegionLMC_HM_RP_MG|LMC.HM.RP.MG]] || Raphe Magnus Nucleus || nucleus-nucleus-ENK || (unknown reference)
+
| [[BrainAreaLMC|LMC]] || [[BrainRegionLMC_MM_PAG|LMC.MM.PAG]] || [[BrainRegionLMC_HL_RP_MG|LMC.HL.RP.MG]] || Raphe Magnus Nucleus || nucleus-nucleus-ENK || (unknown reference)
 
|-
 
|-
−
|  ||  || [[BrainRegionLMC_HM_RP_PL|LMC.HM.RP.PL]] || Raphe Pallidus Nucleus || nucleus-nucleus-ENK || (unknown reference)
+
|  ||  || [[BrainRegionLMC_HL_RP_PL|LMC.HL.RP.PL]] || Raphe Pallidus Nucleus || nucleus-nucleus-ENK || (unknown reference)
 
|-
 
|-
 
| [[BrainAreaLPC|LPC]] || [[BrainRegionLMC_MM_PAG|LMC.MM.PAG]] || [[BrainRegionLPC_FD_TH_PV|LPC.FD.TH.PV]] || Paraventricular Nucleus of Thalamus || nucleus-nucleus-ENK || (unknown reference)
 
| [[BrainAreaLPC|LPC]] || [[BrainRegionLMC_MM_PAG|LMC.MM.PAG]] || [[BrainRegionLPC_FD_TH_PV|LPC.FD.TH.PV]] || Paraventricular Nucleus of Thalamus || nucleus-nucleus-ENK || (unknown reference)
 
|-
 
|-
−
|  ||  || [[BrainRegionLPC_HM_AMB|LPC.HM.AMB]] || Ambiguus Nucleus || nucleus-nucleus-ENK || (unknown reference)
+
|  ||  || [[BrainRegionLPC_HL_AMB|LPC.HL.AMB]] || Ambiguus Nucleus || nucleus-nucleus-ENK || (unknown reference)
 
|-
 
|-
−
| [[BrainAreaLRC|LRC]] || [[BrainRegionLMC_MM_PAG|LMC.MM.PAG]] || [[BrainRegionLRC_HM_RA|LRC.HM.RA]] || Retroambigualis Nucleus || nucleus-nucleus-ENK || (unknown reference)
+
| [[BrainAreaLRC|LRC]] || [[BrainRegionLMC_MM_PAG|LMC.MM.PAG]] || [[BrainRegionLRC_HL_RA|LRC.HL.RA]] || Retroambigualis Nucleus || nucleus-nucleus-ENK || (unknown reference)
 
|-
 
|-
−
|  ||  || [[BrainRegionLRC_HP_PN_SC|LRC.HP.PN.SC]] || Nucleus Subceruleus || nucleus-nucleus-ENK || (unknown reference)
+
|  ||  || [[BrainRegionLRC_HT_NSC|LRC.HT.NSC]] || Nucleus Subceruleus || nucleus-nucleus-ENK || (unknown reference)
 
|}
 
|}
  
Line 326: Line 326:
 
| '''Component ID''' || '''Component Name''' || '''Type''' || '''Service''' || '''Function''' || '''Comments'''
 
| '''Component ID''' || '''Component Name''' || '''Type''' || '''Service''' || '''Function''' || '''Comments'''
 
|-
 
|-
−
| [[BrainRegionLMC_HP_LC|LMC.HP.LC]] || Locus Coeruleus || nucleus || LUS || Regulate the intensity of responses to salient stimuli || NE Source, enhance signal-to-noise ratio,<BR>suppressing irrelevant stimuli (lateral<BR>inhibition); inhibitory nucleus
+
| [[BrainRegionLMC_HT_LC|LMC.HT.LC]] || Locus Coeruleus || nucleus || LUS || Regulate the intensity of responses to salient stimuli || NE Source, enhance signal-to-noise ratio,<BR>suppressing irrelevant stimuli (lateral<BR>inhibition); inhibitory nucleus
 
|}
 
|}
  
Line 339: Line 339:
 
| <font color="red">Cortical</font> || || || || ||
 
| <font color="red">Cortical</font> || || || || ||
 
|-
 
|-
−
| [[BrainAreaNDM|NDM]] || [[BrainRegionLMC_HP_LC|LMC.HP.LC]] || [[BrainRegionNDM_NC_AL_VACG|NDM.NC.AL.VACG]] || Ventral Anterior Cingulate Area || neocortex-nucleus || [http://www.frontiersin.org/neuroanatomy/10.3389/fnana.2011.00034/full Vocal Control (Premotor24 -> RF, abstract)]
+
| [[BrainAreaNDM|NDM]] || [[BrainRegionLMC_HT_LC|LMC.HT.LC]] || [[BrainRegionNDM_NC_AL_VACG|NDM.NC.AL.VACG]] || Ventral Anterior Cingulate Area || neocortex-nucleus || (unknown reference)
 
|-
 
|-
 
| <font color="red">Subcortical</font> || || || || ||
 
| <font color="red">Subcortical</font> || || || || ||
 
|-
 
|-
−
| [[BrainAreaFAM|FAM]] || [[BrainRegionLMC_HP_LC|LMC.HP.LC]] || [[BrainRegionFAM_FT_AM_CEM|FAM.FT.AM.CEM]] || Medial Central Amygdaloid Nucleus || nucleus-nucleus || [http://neuropolitics.org/defaultmay10.asp Amygdalar disruption of prefrontal cortex (AM -> LC, abstract)]
+
| [[BrainAreaFAM|FAM]] || [[BrainRegionLMC_HT_LC|LMC.HT.LC]] || [[BrainRegionFAM_FT_AM_CEM|FAM.FT.AM.CEM]] || Medial Central Amygdaloid Nucleus || nucleus-nucleus || [http://neuropolitics.org/defaultmay10.asp Amygdalar disruption of prefrontal cortex (AM -> LC, abstract)]
 
|-
 
|-
 
|  ||  || [[BrainRegionFAM_FT_BNST|FAM.FT.BNST]] || Bed Nucleus of Stria Terminalis || nucleus-nucleus || (unknown reference)
 
|  ||  || [[BrainRegionFAM_FT_BNST|FAM.FT.BNST]] || Bed Nucleus of Stria Terminalis || nucleus-nucleus || (unknown reference)
 
|-
 
|-
−
| [[BrainAreaLAC|LAC]] || [[BrainRegionLMC_HP_LC|LMC.HP.LC]] || [[BrainRegionLAC_FD_HT_DM|LAC.FD.HT.DM]] || Dorsomedial Hypothalamic Nucleus || nucleus-nucleus || (unknown reference)
+
| [[BrainAreaLAC|LAC]] || [[BrainRegionLMC_HT_LC|LMC.HT.LC]] || [[BrainRegionLAC_FD_HT_DM|LAC.FD.HT.DM]] || Dorsomedial Hypothalamic Nucleus || nucleus-nucleus || (unknown reference)
 
|-
 
|-
 
|  ||  || [[BrainRegionLAC_FD_HT_TBM|LAC.FD.HT.TBM]] || Tuberomammillary Nucleus || nucleus-nucleus || (unknown reference)
 
|  ||  || [[BrainRegionLAC_FD_HT_TBM|LAC.FD.HT.TBM]] || Tuberomammillary Nucleus || nucleus-nucleus || (unknown reference)
 
|-
 
|-
−
| [[BrainAreaLRC|LRC]] || [[BrainRegionLMC_HP_LC|LMC.HP.LC]] || [[BrainRegionLRC_HM_RF_MED|LRC.HM.RF.MED]] || Central Medullary Reticular Nucleus || nucleus-nucleus || (unknown reference)
+
| [[BrainAreaLRC|LRC]] || [[BrainRegionLMC_HT_LC|LMC.HT.LC]] || [[BrainRegionLRC_HL_RF_MED|LRC.HL.RF.MED]] || Central Medullary Reticular Nucleus || nucleus-nucleus || (unknown reference)
 
|}
 
|}
  
Line 361: Line 361:
 
| <font color="red">Subcortical</font> || || || || ||
 
| <font color="red">Subcortical</font> || || || || ||
 
|-
 
|-
−
| [[BrainAreaFAM|FAM]] || [[BrainRegionLMC_HP_LC|LMC.HP.LC]] || [[BrainRegionFAM_FD_MHB|FAM.FD.MHB]] || Medial Habenula || nucleus-nucleus-NE || (unknown reference)
+
| [[BrainAreaFAM|FAM]] || [[BrainRegionLMC_HT_LC|LMC.HT.LC]] || [[BrainRegionFAM_FD_MHB|FAM.FD.MHB]] || Medial Habenula || nucleus-nucleus-NE || (unknown reference)
 
|-
 
|-
 
|  ||  || [[BrainRegionFAM_FT_SEP_DBB|FAM.FT.SEP.DBB]] || Diagonal Band of Broca || nucleus-nucleus-NE || (unknown reference)
 
|  ||  || [[BrainRegionFAM_FT_SEP_DBB|FAM.FT.SEP.DBB]] || Diagonal Band of Broca || nucleus-nucleus-NE || (unknown reference)
 
|-
 
|-
−
| [[BrainAreaFEC|FEC]] || [[BrainRegionLMC_HP_LC|LMC.HP.LC]] || [[BrainRegionFEC_FT_SNC_MED|FEC.FT.SNC.MED]] || Substantia Nigra Pars Compacta Medial || nucleus-nucleus-NE || (unknown reference)
+
| [[BrainAreaFEC|FEC]] || [[BrainRegionLMC_HT_LC|LMC.HT.LC]] || [[BrainRegionFEC_FT_SNC_MED|FEC.FT.SNC.MED]] || Substantia Nigra Pars Compacta Medial || nucleus-nucleus-NE || (unknown reference)
 
|-
 
|-
−
| [[BrainAreaLAC|LAC]] || [[BrainRegionLMC_HP_LC|LMC.HP.LC]] || [[BrainRegionLAC_SC_IZ_IML|LAC.SC.IZ.IML]] || Intermediolateral Nucleus || nucleus-nucleus-NE || [http://www.intechopen.com/books/computational-intelligence-in-electromyography-analysis-a-perspective-on-current-applications-and-future-challenges/sphincter-emg-for-diagnosing-multiple-system-atrophy-and-related-disorders Physiology and pathophysiology of lower urinary tract (LC -> IML)]
+
| [[BrainAreaLAC|LAC]] || [[BrainRegionLMC_HT_LC|LMC.HT.LC]] || [[BrainRegionLAC_SC_IZ_IML|LAC.SC.IZ.IML]] || Intermediolateral Nucleus || nucleus-nucleus-NE || [http://www.intechopen.com/books/computational-intelligence-in-electromyography-analysis-a-perspective-on-current-applications-and-future-challenges/sphincter-emg-for-diagnosing-multiple-system-atrophy-and-related-disorders Physiology and pathophysiology of lower urinary tract (LC -> IML)]
 
|}
 
|}
  

Revision as of 10:02, 28 July 2015

Modulatory Contol Area

Home -> BiologicalLifeResearch -> BrainAreaLMC

Local Circuits

(generated)

ID Name Regions
5HT Serotonin - Feelings of Well-Being and Happiness LMC.HL.RP.MG, LMC.HL.RP.OB, LMC.HL.RP.PL, LMC.HP.RP.LI, LMC.HP.RP.PRN, LMC.MM.RF.SUC, LMC.MM.RP.DRN
ACH Acetylcholine - PNS Actions and CNS plasticity, arousal and reward LMC.FT.NBM, LMC.HT.TG.DTG, LMC.HT.TG.LDT, LMC.HT.TG.VTG
DA Dopamine - Reward-Motivated Behavior, Cognitive Alertness LMC.MM.VTA
ENK Enkephalin - Regulating Nociception in Body LMC.MM.PAG
NE Norepinephrine - Vigilant Concentration, Stress Hormone, Fight-or-Flight Response LMC.HT.LC

Serotonin - Feelings of Well-Being and Happiness

unavailable

Component ID Component Name Type Service Function Comments
LMC.HL.RP.MG Raphe Magnus Nucleus nucleus LUS Inhubit head and spinal pain B3, contacts with enkephalenic neurons in
substantia gelatinosa
LMC.HL.RP.OB Raphe Obscurus Nucleus nucleus LUS Regulate cardiovascular function via sympathetic spinal column B2
LMC.HL.RP.PL Raphe Pallidus Nucleus nucleus LUS Spinal pain control B1
LMC.HP.RP.LI Raphe Nucleus Linearis nucleus LUS Release of 5-HT was only obtained on stimulation of this nucleus B8, Does not project to CR, but to forebrain, to
dorsal raphe nucleus (lies above DRN); dendrites to
vascular plexus, maybe sensing blood pressure
LMC.HP.RP.PRN Pontine Raphe Nucleus nucleus LUS Regulation of sleep cycle Projects to CR, forebrain; inhibitory nucleus
LMC.MM.RF.SUC Superior Central Raphe Nucleus nucleus LUS Block or temporarily suspend mnemonic processes in the hippocampus;
Hallucinations 		Directs HC to disregard insignificant events;
inhibitory nucleus; B6,B8; Insomnia; inhibitory
nucleus
LMC.MM.RP.DRN Dorsal Raphe Nucleus nucleus LUS Regulation of sleep and mood Major source of 5HT; inhibitory nucleus

Internal Region Connections:

Source Region Target Region Type Reference
LMC.HP.RP.LI LMC.MM.RP.DRN nucleus-nucleus-5HT (unknown reference)

External Inbound Region Connections:

Source Area Local Region Source Region Source Name Type Reference
Subcortical
FAM LMC.MM.RF.SUC FAM.FD.LHB.MED Lateral Habenula Medial Part nucleus-nucleus Habenula Connections (LHb -> MR, abstract)
LMC.MM.RP.DRN FAM.FD.LHB.MED Lateral Habenula Medial Part nucleus-nucleus Habenula Connections (LHb -> DR, abstract)
LAC LMC.HL.RP.MG LAC.FD.HT.LTN Lateral Hypothalamic Nucleus nucleus-nucleus (unknown reference)
LAC.FD.HT.PV Paraventricular Nucleus nucleus-nucleus (unknown reference)
LMC.HL.RP.OB LAC.FD.HT.PO Preoptic Nucleus nucleus-nucleus (unknown reference)
LLC LMC.HL.RP.MG LLC.MM.SCNF Subcuneiform Nucleus nucleus-nucleus (unknown reference)
LMC.HP.RP.PRN LLC.MM.SCNF Subcuneiform Nucleus nucleus-nucleus (unknown reference)
LMC.MM.RP.DRN LLC.FD.TH.SF Subfascicular Nucleus of Thalamus nucleus-nucleus-gaba (unknown reference)
LMC LMC.HL.RP.MG LMC.MM.PAG Periaqueductal Gray Matter nucleus-nucleus-ENK (unknown reference)
LMC.HL.RP.PL LMC.MM.PAG Periaqueductal Gray Matter nucleus-nucleus-ENK (unknown reference)

External Outbound Region Connections:

Target Area Local Region Target Region Target Name Type Reference
Subcortical
FAM LMC.MM.RF.SUC FAM.FD.LHB.LT Lateral Habenula Lateral Part nucleus-nucleus-5HT (unknown reference)
FAM.FT.SEP.LT Lateral Septal Nucleus nucleus-nucleus-5HT (unknown reference)
FEC LMC.MM.RF.SUC FEC.FD.STN.ICD Subthalamic Nucleus Internal Caudal nucleus-nucleus-5HT (unknown reference)
FMM LMC.MM.RF.SUC FMM.FD.MB.MMB Medial Mammillary Nucleus nucleus-nucleus-5HT (unknown reference)
LAC LMC.MM.RF.SUC LAC.FD.HT.PN Posterior Hypothalamic Nucleus nucleus-nucleus-5HT (unknown reference)
LAC.FD.HT.SUM Supramammillary Nucleus nucleus-nucleus-5HT (unknown reference)
LLC LMC.HL.RP.OB LLC.HT.CR.SC Spinocerebellum nucleus-allocortex-5HT (unknown reference)
LMC.HP.RP.PRN LLC.HT.CR.SC Spinocerebellum nucleus-allocortex-5HT (unknown reference)
LPC LMC.HL.RP.MG LPC.SC.PH.LSG Lower Substantia Gelatinosa nucleus-nucleus-5HT (unknown reference)
LPC.SC.PH.USG Upper Substantia Gelatinosa nucleus-nucleus-5HT (unknown reference)
LMC.HL.RP.OB LPC.SC.IZ.IMM Intermediomedial Nucleus nucleus-nucleus-5HT (unknown reference)
LMC.HL.RP.PL LPC.SC.PH.LMG Lower Marginal Nucleus nucleus-nucleus-5HT (unknown reference)
LPC.SC.PH.UMG Upper Marginal Nucleus nucleus-nucleus-5HT (unknown reference)
LMC.MM.RP.DRN LPC.FD.TH.PV Paraventricular Nucleus of Thalamus nucleus-nucleus-5HT (unknown reference)

Acetylcholine - PNS Actions and CNS plasticity, arousal and reward

unavailable

Component ID Component Name Type Service Function Comments
LMC.FT.NBM Basal Nucleus of Meynert nucleus FAU Control imagination vs perception ACh source, attention; modulatory nucleus
LMC.HT.TG.DTG Dorsal Tegmental Nucleus nucleus LUS accurate landmark navigation vestibular sensory information to mammllary bodies
for orientation
LMC.HT.TG.LDT Laterodorsal Tegmental Nucleus nucleus LUS Modulating sustained attention or in mediating alerting responses sleep, waking, motor function, learning and reward
LMC.HT.TG.VTG Ventral Tegmental Nucleus nucleus LUS moderates hippocampal-driven rhythmic firing frequency in medial mammillary contribute to episodic memory and new learning in
humans as well as spatial memory

Internal Region Connections:

  • no connections

External Inbound Region Connections:

Source Area Local Region Source Region Source Name Type Reference
Cortical
NSA LMC.HT.TG.LDT NSA.FD.TH.SG Suprageniculate Nucleus of Thalamus nucleus-nucleus Head Direction Cell Circuit (SUPGEN -> DTN)
Subcortical
FAM LMC.FT.NBM FAM.FT.AM.AB Accessory Basal Amygdaloid Nucleus nucleus-nucleus (unknown reference)
FAM.FT.AM.BP Parvicellular Basal Amygdaloid Nucleus nucleus-nucleus (unknown reference)
FAM.FT.AM.CEM Medial Central Amygdaloid Nucleus nucleus-nucleus (unknown reference)
FAM.FT.BNST Bed Nucleus of Stria Terminalis nucleus-nucleus (unknown reference)
LMC.HT.TG.DTG FAM.FD.LHB.MED Lateral Habenula Medial Part nucleus-nucleus (unknown reference)
LMC.HT.TG.VTG FAM.FD.LHB.MED Lateral Habenula Medial Part nucleus-nucleus (unknown reference)
FEC LMC.FT.NBM FEC.FD.STN.CD Subthalamic Nucleus Caudal nucleus-nucleus (unknown reference)
FEC.FT.ACC.SH Nucleus Accumbens Shell nucleus-nucleus-gaba Affective basal ganglia circuit (NACC -> nBM, abstract)
LMC.HT.TG.LDT FEC.HT.PPN.RMTG Rostromedial Tegmental Nucleus nucleus-nucleus-gaba (unknown reference)
FMM LMC.HT.TG.LDT FMM.FD.MB.LMB Lateral Mammillary Nucleus nucleus-nucleus Head Direction Cell Circuit (LMB -> DTN)
LRC LMC.HT.TG.DTG LRC.HL.NPH Prepositus Nucleus nucleus-nucleus (unknown reference)

External Outbound Region Connections:

Target Area Local Region Target Region Target Name Type Reference
Cortical
NDM LMC.FT.NBM NDM.NC.AL.FPC Lateral Frontopolar Cortex nucleus-neocortex-ACh Physiology and pathophysiology of lower urinary tract (NBM -> MPFC, abstract)
NSA LMC.FT.NBM NSA.NC.OCC.V1 Primary Visual Cortex nucleus-neocortex-ACh (unknown reference)
Subcortical
FAM LMC.FT.NBM FAM.FT.AM.BM Magnocellular Basal Amygdaloid Nucleus nucleus-nucleus-ACh (unknown reference)
FEC LMC.HT.TG.LDT FEC.HT.PPN.IPD Interpeduncular Nucleus nucleus-nucleus-ACh Head Direction Cell Circuit (DTN -> IPD)
FMM LMC.HT.TG.DTG FMM.FD.MB.LMB Lateral Mammillary Nucleus nucleus-nucleus-ACh (unknown reference)
LMC.HT.TG.VTG FMM.FD.MB.MMB Medial Mammillary Nucleus nucleus-nucleus (unknown reference)
LAC LMC.HT.TG.LDT LAC.HL.SAL.ISL Inferior Salivatory Nucleus nucleus-nucleus-ACh (unknown reference)
LAC.HL.SAL.SSL Superior Salivatory Nucleus nucleus-nucleus-ACh (unknown reference)
LMC LMC.HT.TG.VTG LMC.MM.VTA Ventral Tegmental Area nucleus-nucleus (unknown reference)
LRC LMC.HT.TG.LDT LRC.HL.NPH Prepositus Nucleus nucleus-nucleus-ACh Head Direction Cell Circuit (DTN -> NPRP)

Dopamine - Reward-Motivated Behavior, Cognitive Alertness

unavailable

Component ID Component Name Type Service Function Comments
LMC.MM.VTA Ventral Tegmental Area nucleus LUS Respond to novel stimuli, unexpected rewards, and reward predictive sensory cues

Internal Region Connections:

  • no connections

External Inbound Region Connections:

Source Area Local Region Source Region Source Name Type Reference
Subcortical
FAM LMC.MM.VTA FAM.FT.BNST Bed Nucleus of Stria Terminalis nucleus-nucleus (unknown reference)
FEC LMC.MM.VTA FEC.FT.ACC.CORE Nucleus Accumbens Core nucleus-nucleus-gaba Reward circuit of human brain (NACC -> VTA, abstract)
FEC.FT.VP.VM Ventral Pallidum Ventromedial nucleus-nucleus-gaba Craving (VPAL -> VTA, abstract)
FEC.HT.PPN.RMTG Rostromedial Tegmental Nucleus nucleus-nucleus-gaba Amygdala and its network (RMTG -> VTA)
LMC LMC.MM.VTA LMC.HT.TG.VTG Ventral Tegmental Nucleus nucleus-nucleus (unknown reference)

External Outbound Region Connections:

Target Area Local Region Target Region Target Name Type Reference
Cortical
NDM LMC.MM.VTA NDM.NC.AL.DACG Dorsal Anterior Cingulate Area nucleus-neocortex-DA (unknown reference)
NDM.NC.AL.FPC Lateral Frontopolar Cortex nucleus-neocortex-DA Amygdala and its network (VTA -> MPFC, abstract)
Subcortical
FAM LMC.MM.VTA FAM.FT.AM.CEC Central Amygdaloid Nucleus, capsular subdivision nucleus-nucleus-DA Reward circuit of human brain (VTA -> AM, abstract)
FEC LMC.MM.VTA FEC.FT.ACC.SH Nucleus Accumbens Shell nucleus-nucleus-DA Craving (VTA -> NACC, abstract)
FMM LMC.MM.VTA FMM.FD.MB.MMB Medial Mammillary Nucleus nucleus-nucleus-DA Mammillary bodies: two memory systems in one (VTN -> MMB)
FMM.FT.HC.CA1D Distal CA1 of Hippocampus nucleus-allocortex-DA Reward circuit of human brain (VTA -> HC, abstract)
FMM.NC.PH.LEC Lateral Entorhinal Cortex nucleus-neocortex-DA Combining Novelty, Motivational Salience, and Reward to Control Attention and Learning (VTA -> EC, abstract)
LAC LMC.MM.VTA LAC.FD.HT.PO Preoptic Nucleus nucleus-nucleus-DA Physiology and pathophysiology of lower urinary tract (VTA -> MPOA)
LAC.FD.HT.PRM Premammillary Nucleus nucleus-nucleus-DA (unknown reference)
LAC.FD.HT.PV Paraventricular Nucleus nucleus-nucleus-DA Physiology and pathophysiology of lower urinary tract (VTA -> PVN)

Enkephalin - Regulating Nociception in Body

unavailable

Component ID Component Name Type Service Function Comments
LMC.MM.PAG Periaqueductal Gray Matter nucleus LUS Descending modulation of pain and in defensive behaviour if there is a lesion in the PAG, then consciousness
is lost; electrical stimulation of the PAG results
in immediate and profound analgesia; modulatory
nucleus

Internal Region Connections:

  • no connections

External Inbound Region Connections:

Source Area Local Region Source Region Source Name Type Reference
Cortical
NCP LMC.MM.PAG NCP.NC.AL.SGCG Subgenual Cingulate Cortex neocortex-nucleus (unknown reference)
Subcortical
FAM LMC.MM.PAG FAM.FT.AM.CEM Medial Central Amygdaloid Nucleus nucleus-nucleus Amygdalar disruption of prefrontal cortex (AM -> PAG, abstract)
LAC LMC.MM.PAG LAC.FD.HT.VM Ventromedial Hypothalamic Nucleus nucleus-nucleus (unknown reference)

External Outbound Region Connections:

Target Area Local Region Target Region Target Name Type Reference
Subcortical
LAC LMC.MM.PAG LAC.HT.BR Barrington's Nucleus nucleus-nucleus-ENK Schematic overview of spinobulbospinal micturition reflex pathway (PAG -> BAR)
LLC LMC.MM.PAG LLC.FD.TH.SF Subfascicular Nucleus of Thalamus nucleus-nucleus-ENK (unknown reference)
LMC LMC.MM.PAG LMC.HL.RP.MG Raphe Magnus Nucleus nucleus-nucleus-ENK (unknown reference)
LMC.HL.RP.PL Raphe Pallidus Nucleus nucleus-nucleus-ENK (unknown reference)
LPC LMC.MM.PAG LPC.FD.TH.PV Paraventricular Nucleus of Thalamus nucleus-nucleus-ENK (unknown reference)
LPC.HL.AMB Ambiguus Nucleus nucleus-nucleus-ENK (unknown reference)
LRC LMC.MM.PAG LRC.HL.RA Retroambigualis Nucleus nucleus-nucleus-ENK (unknown reference)
LRC.HT.NSC Nucleus Subceruleus nucleus-nucleus-ENK (unknown reference)

Norepinephrine - Vigilant Concentration, Stress Hormone, Fight-or-Flight Response

unavailable

Component ID Component Name Type Service Function Comments
LMC.HT.LC Locus Coeruleus nucleus LUS Regulate the intensity of responses to salient stimuli NE Source, enhance signal-to-noise ratio,
suppressing irrelevant stimuli (lateral
inhibition); inhibitory nucleus

Internal Region Connections:

  • no connections

External Inbound Region Connections:

Source Area Local Region Source Region Source Name Type Reference
Cortical
NDM LMC.HT.LC NDM.NC.AL.VACG Ventral Anterior Cingulate Area neocortex-nucleus (unknown reference)
Subcortical
FAM LMC.HT.LC FAM.FT.AM.CEM Medial Central Amygdaloid Nucleus nucleus-nucleus Amygdalar disruption of prefrontal cortex (AM -> LC, abstract)
FAM.FT.BNST Bed Nucleus of Stria Terminalis nucleus-nucleus (unknown reference)
LAC LMC.HT.LC LAC.FD.HT.DM Dorsomedial Hypothalamic Nucleus nucleus-nucleus (unknown reference)
LAC.FD.HT.TBM Tuberomammillary Nucleus nucleus-nucleus (unknown reference)
LRC LMC.HT.LC LRC.HL.RF.MED Central Medullary Reticular Nucleus nucleus-nucleus (unknown reference)

External Outbound Region Connections:

Target Area Local Region Target Region Target Name Type Reference
Subcortical
FAM LMC.HT.LC FAM.FD.MHB Medial Habenula nucleus-nucleus-NE (unknown reference)
FAM.FT.SEP.DBB Diagonal Band of Broca nucleus-nucleus-NE (unknown reference)
FEC LMC.HT.LC FEC.FT.SNC.MED Substantia Nigra Pars Compacta Medial nucleus-nucleus-NE (unknown reference)
LAC LMC.HT.LC LAC.SC.IZ.IML Intermediolateral Nucleus nucleus-nucleus-NE Physiology and pathophysiology of lower urinary tract (LC -> IML)

Thirdparty Circuits

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References

(generated)

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