BrainAreaNDM

Decision Making Area

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Local Circuits

(generated)

ID	Name	Regions
HLC	High-Level Control	NDM.FD.TH.MDM, NDM.NC.AL.FPC
HLNM	High-Level Novelty Attention	NDM.NC.AL.ROFCL, NDM.NC.AL.ROFCM, NDM.NC.AL.ROFCR, NDM.NC.AL.ROFCS
HWM	Working Memory	NDM.NC.AL.DLPFCL, NDM.NC.AL.DLPFCR
MAS	Motivatory Associations	NDM.FD.TH.PV, NDM.FD.TH.SM, NDM.NC.AL.DMPFC, NDM.NC.AL.IPG, NDM.NC.AL.VMPFC
MRS	Motivational Responses	NDM.NC.AL.DMCG, NDM.NC.AL.PGCG, NDM.NC.AL.VMCG
UMC	Unimodal Control	NDM.NC.AL.DACG, NDM.NC.AL.VACG

High-Level Control

Component ID	Component Name	Type	Service	Function	Comments
NDM.FD.TH.MDM	Medial Mediodorsal Nucleus of Thalamus	nucleus	NPU	relay emotional attention to orbitofrontal cortex	orbitofrontal cortex (BA12,13) defined by MDm projection; relay AM-Bp to OFC; OFCm - subjective pleasantness, OFCl - subjective unpleasantness
NDM.NC.AL.FPC	Lateral Frontopolar Cortex	cortex, BA 10	NPU	Emotion Regulation	Frontopolar area, contains ILC - infralimbic cortex

Internal Region Connections:

Source Region	Target Region	Type	Reference
NDM.FD.TH.MDM	NDM.NC.AL.FPC	nucleus-neocortex	Amygdala and its network (MD -> MPFC, abstract)

External Inbound Region Connections:

Source Area	Local Region	Source Region	Source Name	Type	Reference
Cortical
NCP	NDM.FD.TH.MDM	NCP.NC.MPL.PSCG	Posterior Cingulate Cortex	neocortex-nucleus	Contributions of Diencephalon to Recognition Memory (PostCingulate -> MDmc, abstract)
	NDM.NC.AL.FPC	NCP.NC.INS.PPC	Peripaleocortical Claustral	neocortex-neocortex	Amygdalar disruption of prefrontal cortex (INS -> MPFC, abstract)
Subcortical
FAM	NDM.FD.TH.MDM	FAM.FT.AM.AB	Accessory Basal Amygdaloid Nucleus	nucleus-nucleus	Prefrontal Cortex (PFC) in emotional behavior (AM -> TH, abstract)
		FAM.FT.AM.BP	Parvicellular Basal Amygdaloid Nucleus	nucleus-nucleus	Amygdala and its network (BLN -> MD, abstract)
		FAM.FT.SEP.MED	Medial Septal Nucleus	nucleus-nucleus-ACh	Thalamocortical relationships (s1MD -> MD, abstract)
FEC	NDM.FD.TH.MDM	FEC.FT.GPI.RM	Globus Pallidus Internal Rostromedial	nucleus-nucleus-gaba	Saccadic Vision (BG -> Thalamus, abstract)
FMM	NDM.FD.TH.MDM	FMM.NC.PH.LEC	Lateral Entorhinal Cortex	neocortex-nucleus	Contributions of Diencephalon to Recognition Memory (EC -> MDmc, abstract)
		FMM.NC.PH.PER	Perirhinal Cortex	neocortex-nucleus	Contributions of Diencephalon to Recognition Memory (Perirhinal -> MDmc, abstract)
LMC	NDM.NC.AL.FPC	LMC.FT.NBM	Basal Nucleus of Meynert	nucleus-neocortex-ACh	Physiology and pathophysiology of lower urinary tract (NBM -> MPFC, abstract)
		LMC.MM.VTA	Ventral Tegmental Area	nucleus-neocortex-DA	Amygdala and its network (VTA -> MPFC, abstract)

External Outbound Region Connections:

Target Area	Local Region	Target Region	Target Name	Type	Reference
Cortical
NDM	NDM.FD.TH.MDM	NDM.NC.AL.DLPFCR	Rostral Mid-Dorsolateral Prefrontal Cortex	nucleus-neocortex	Prefrontal Cortex (PFC) in emotional behavior (TH -> LPFC, abstract)
	NDM.NC.AL.FPC	NDM.NC.AL.DLPFCR	Rostral Mid-Dorsolateral Prefrontal Cortex	neocortex-neocortex	Prefrontal Cortex (PFC) in emotional behavior (OPFC -> LPFC, abstract)
		NDM.NC.AL.VACG	Ventral Anterior Cingulate Area	neocortex-neocortex	Role for serotonin in moral behavior (OMPFC -> ACG, abstract)
Subcortical
FAM	NDM.NC.AL.FPC	FAM.FT.AM.BM	Magnocellular Basal Amygdaloid Nucleus	neocortex-nucleus	Bowels control brain: gut hormones and obesity (OFC -> AMY, abstract)
		FAM.FT.AM.BP	Parvicellular Basal Amygdaloid Nucleus	neocortex-nucleus	Amygdala and its network (MPFC -> BLN, abstract)
		FAM.FT.SEP.SH	Septohippocampal Nucleus	neocortex-nucleus	(unknown reference)
FEC	NDM.NC.AL.FPC	FEC.FT.ACC.CORE	Nucleus Accumbens Core	neocortex-nucleus	Affective basal ganglia circuit (OMPFC -> NACC, abstract)
		FEC.FT.SNR.MED	Substantia Nigra Pars Reticulata Medial	neocortex-nucleus	Global visual system (FrontalCortex -> BGA, abstract)
LAC	NDM.NC.AL.FPC	LAC.FD.HT.RCH	Retrochiasmatic Nucleus	neocortex-nucleus	Prefrontal Cortex (PFC) in emotional behavior (OPFC -> HT, abstract)

High-Level Novelty Attention

Component ID	Component Name	Type	Service	Function	Comments
NDM.NC.AL.ROFCL	Lateral Rostral Orbitofrontal Cortex	cortex, BA 12	NPU	Visual selection of novelty	12L
NDM.NC.AL.ROFCM	Medial Rostral Orbitofrontal Cortex	cortex, BA 12	NPU	Somatosensory selection of novelty	12M
NDM.NC.AL.ROFCR	Most Rostral Orbitofrontal Cortex	cortex, BA 12	NPU	Integral conscious selection of novelty	12R
NDM.NC.AL.ROFCS	Sulcal Rostral Orbitofrontal Cortex	cortex, BA 12	NPU	Gustatory and auditory selection of novelty	12S

Internal Region Connections:

Source Region	Target Region	Type	Reference
NDM.NC.AL.ROFCL	NDM.NC.AL.ROFCR	neocortex-neocortex	Regulation of Social Brain (MPFC -> OFC, abstract)
NDM.NC.AL.ROFCM	NDM.NC.AL.ROFCL	neocortex-neocortex	Regulation of Social Brain (MPFC -> OFC, abstract)
	NDM.NC.AL.ROFCR	neocortex-neocortex	Regulation of Social Brain (MPFC -> OFC, abstract)
NDM.NC.AL.ROFCS	NDM.NC.AL.ROFCL	neocortex-neocortex	Regulation of Social Brain (MPFC -> OFC, abstract)

External Inbound Region Connections:

Source Area	Local Region	Source Region	Source Name	Type	Reference
Cortical
NCP	NDM.NC.AL.ROFCM	NCP.NC.SPL.SA	Somatosensory Association Cortex	neocortex-neocortex	Cortico-Cortical Connectivity (SA -> PFC, abstract)
	NDM.NC.AL.ROFCR	NCP.NC.MPL.RSC	Retrosplenial Cortex	neocortex-neocortex	Prefrontal Cortex (PFC) in emotional behavior (PCA -> OPFC, abstract)
	NDM.NC.AL.ROFCS	NCP.NC.PO.PCC	Precentral Cortex	neocortex-neocortex	Global visual system (ParietalCortex -> FrontalCortex, abstract)
NDM	NDM.NC.AL.ROFCS	NDM.FD.TH.PV	Paraventricular Nucleus of Thalamus	nucleus-neocortex	Saccadic Vision (Thalamus -> FrontalCortex, abstract)
NPE	NDM.NC.AL.ROFCL	NPE.FD.TH.MPV	Medial Pulvinar	nucleus-neocortex	Saccadic Vision (Thalamus -> FrontalCortex, abstract)
Subcortical
FAM	NDM.NC.AL.ROFCR	FAM.FD.TH.PT	Paratenial Nucleus of Thalamus	nucleus-neocortex	Saccadic Vision (Thalamus -> FrontalCortex, abstract)
FMM	NDM.NC.AL.ROFCR	FMM.FT.HC.CA1D	Distal CA1 of Hippocampus	allocortex-neocortex	Simplified model of hippocampal formation anatomy (CA1 -> mPFC, abstract)
		FMM.FT.HF.SUBD	Distal Subiculum	allocortex-neocortex	Simplified model of hippocampal formation anatomy (SUB -> mPFC, abstract)
LAC	NDM.NC.AL.ROFCS	LAC.FD.HT.LTN	Lateral Hypothalamic Nucleus	nucleus-neocortex	Bowels control brain: gut hormones and obesity (LHA -> OFC, abstract)
		LAC.FD.HT.PV	Paraventricular Nucleus	nucleus-neocortex	Bowels control brain: gut hormones and obesity (PVN -> OFC, abstract)

External Outbound Region Connections:

Target Area	Local Region	Target Region	Target Name	Type	Reference
Cortical
NDM	NDM.NC.AL.ROFCR	NDM.NC.AL.DACG	Dorsal Anterior Cingulate Area	neocortex-neocortex	Role for serotonin in moral behavior (OMPFC -> ACG, abstract)
		NDM.NC.AL.IPG	Inferior Prefrontal Gyrus	neocortex-neocortex	Regulation of Social Brain (OFC -> IFG, abstract)
Subcortical
FEC	NDM.NC.AL.ROFCR	FEC.FD.STN.DL	Subthalamic Nucleus Dorsolateral	neocortex-nucleus	Serotonin regulation of subthalamic neurons (CTX -> STN, abstract)
		FEC.FT.CN.TL	Caudate Nucleus Tail	neocortex-nucleus	Global visual system (FrontalCortex -> BGA, abstract)
FMM	NDM.NC.AL.ROFCR	FMM.FD.TH.RE	Reuniens Nucleus of Thalamus	neocortex-nucleus	(unknown reference)
		FMM.FD.TH.RH	Rhomboidal Nucleus of Thalamus	neocortex-nucleus	(unknown reference)

Working Memory

Component ID	Component Name	Type	Service	Function	Comments
NDM.NC.AL.DLPFCL	Lateral Mid-Dorsolateral Prefrontal Cortex	cortex, BA 46	NPU	Cognitive control related to stimulus processing and selection of relevant information for behavior
NDM.NC.AL.DLPFCR	Rostral Mid-Dorsolateral Prefrontal Cortex	cortex, BA 46	NPU	Cognitive control and monitoring to resolve conflict in information processing and competing response plans

Internal Region Connections:

• no connections

External Inbound Region Connections:

Source Area	Local Region	Source Region	Source Name	Type	Reference
Cortical
NCP	NDM.NC.AL.DLPFCR	NCP.NC.MPL.RSC	Retrosplenial Cortex	neocortex-neocortex	Prefrontal Cortex (PFC) in emotional behavior (PCA -> LPFC, abstract)
NDM	NDM.NC.AL.DLPFCL	NDM.NC.AL.IPG	Inferior Prefrontal Gyrus	neocortex-neocortex	Directed Effort Network (fPole -> DLPFC, abstract)
	NDM.NC.AL.DLPFCR	NDM.FD.TH.MDM	Medial Mediodorsal Nucleus of Thalamus	nucleus-neocortex	Prefrontal Cortex (PFC) in emotional behavior (TH -> LPFC, abstract)
		NDM.NC.AL.FPC	Lateral Frontopolar Cortex	neocortex-neocortex	Prefrontal Cortex (PFC) in emotional behavior (OPFC -> LPFC, abstract)
		NDM.NC.AL.VACG	Ventral Anterior Cingulate Area	neocortex-neocortex	Role for serotonin in moral behavior (ACG -> LPFC, abstract)
NMA	NDM.NC.AL.DLPFCL	NMA.NC.PMC.F4	Ventral Caudal Premotor Cortex	neocortex-neocortex	Cortico-Cortical Connectivity (MA -> PFC, abstract)
NPE	NDM.NC.AL.DLPFCL	NPE.FD.TH.MPV	Medial Pulvinar	nucleus-neocortex	Saccadic Vision (Thalamus -> FrontalCortex, abstract)
	NDM.NC.AL.DLPFCR	NPE.NC.IPL.MST	Medial Superior Temporal Area	neocortex-neocortex	Cortico-Cortical Connectivity (PTHA -> PFC, abstract)
		NPE.NC.IPS.LIP	Lateral Intraparietal Sulcus	neocortex-neocortex	Summary of eye movement control (PEF -> DLPFC, abstract)
NSA	NDM.NC.AL.DLPFCL	NSA.NC.IT.TE	Inferotemporal Cortex	neocortex-neocortex	3 Visual Cortex Paths (IT -> LPC, abstract)
		NSA.NC.OCC.V2TN	Secondary Visual Cortex, Thin Stripe	neocortex-neocortex	Cortico-Cortical Connectivity (VA -> PFC, abstract)
Subcortical
LLC	NDM.NC.AL.DLPFCL	LLC.HT.CR.DN	Dentate Nucleus	nucleus-neocortex	(unknown reference)

External Outbound Region Connections:

Target Area	Local Region	Target Region	Target Name	Type	Reference
Cortical
NDM	NDM.NC.AL.DLPFCR	NDM.NC.AL.DACG	Dorsal Anterior Cingulate Area	neocortex-neocortex	Prefrontal Cortex (PFC) in emotional behavior (LPFC -> ACG, abstract)
		NDM.NC.AL.VMPFC	Ventromedial Prefrontal Cortex	neocortex-neocortex	Fear regulation (dlPFC -> vmPFC, abstract)
NMA	NDM.NC.AL.DLPFCL	NMA.FD.TH.VA	Ventral Anterior Nucleus	neocortex-nucleus	Prefrontal Cortex (PFC) in motor behavior (LPFC -> TH, abstract)
		NMA.NC.PMC.F5	Ventral Rostral Premotor Cortex	neocortex-neocortex	Prefrontal Cortex (PFC) in motor behavior (LPFC -> PMC, abstract)
	NDM.NC.AL.DLPFCR	NMA.NC.PMC.F7	Dorsal Rostral Premotor Cortex	neocortex-neocortex	Prefrontal Cortex (PFC) in motor behavior (LPFC -> PMC, abstract)
		NMA.NC.SMC.F6	Pre-Supplementary Motor Area	neocortex-neocortex	Primate Control of Grasping (46 -> F6, abstract)
NPE	NDM.NC.AL.DLPFCL	NPE.NC.PMC.AFEF	Anterior Frontal Eye Field	neocortex-neocortex	Prefrontal Cortex (PFC) in motor behavior (LPFC -> PMC, abstract)
	NDM.NC.AL.DLPFCR	NPE.NC.SMC.SEF	Supplementary Eye Field	neocortex-neocortex	3 Visual Cortex Paths (LPC -> pre-SMA, abstract)
Subcortical
FEC	NDM.NC.AL.DLPFCL	FEC.FT.CN.HD	Caudate Nucleus Head	neocortex-nucleus	Global visual system (FrontalCortex -> BGA, abstract)

Motivatory Associations

Component ID	Component Name	Type	Service	Function	Comments
NDM.FD.TH.PV	Paraventricular Nucleus of Thalamus	nucleus	NPU	Direct behavior toward a particular outcome over a range of outcomes	Projects like PT, but more to BNST, AM
NDM.FD.TH.SM	Submedial Nucleus of Thalamus	nucleus	NPU	Pain center	Projections from SC Lamina I, trigeminal nucleus to ACC
NDM.NC.AL.DMPFC	Dorsomedial Prefrontal Cortex	cortex, BA 09	NPU	Ongoing Extroverted Attention to Select Appropriate Response	upper MPFC, primary connections to the cingulate and the motor and premotor cortices
NDM.NC.AL.IPG	Inferior Prefrontal Gyrus	cortex, BA 47	NPU	Processing of syntax in oral and sign languages	Personality, endurance
NDM.NC.AL.VMPFC	Ventromedial Prefrontal Cortex	cortex, BA 11	NPU	Ongoing Introverted Attention with Regard to Emotions and Feelings, Reward or Punishment	lower MPFC, primary connections to limbic and sensory cortices; Reward mediated behaviours

Internal Region Connections:

Source Region	Target Region	Type	Reference
NDM.FD.TH.PV	NDM.NC.AL.VMPFC	nucleus-neocortex	Saccadic Vision (Thalamus -> FrontalCortex, abstract)
NDM.FD.TH.SM	NDM.NC.AL.DMPFC	nucleus-neocortex	Saccadic Vision (Thalamus -> FrontalCortex, abstract)
NDM.NC.AL.IPG	NDM.NC.AL.DMPFC	neocortex-neocortex	(unknown reference)

External Inbound Region Connections:

Source Area	Local Region	Source Region	Source Name	Type	Reference
Cortical
NCP	NDM.NC.AL.IPG	NCP.NC.INS.AIC	Anterior Insular Cortex	neocortex-neocortex	Directed Effort Network (Insula -> fPole, abstract)
		NCP.NC.TPC	Temporopolar Cortex	neocortex-neocortex	Language-Related Regions (TC -> vIFC)
NDM	NDM.NC.AL.IPG	NDM.NC.AL.ROFCR	Most Rostral Orbitofrontal Cortex	neocortex-neocortex	Regulation of Social Brain (OFC -> IFG, abstract)
	NDM.NC.AL.VMPFC	NDM.NC.AL.DLPFCR	Rostral Mid-Dorsolateral Prefrontal Cortex	neocortex-neocortex	Fear regulation (dlPFC -> vmPFC, abstract)
Subcortical
FAM	NDM.FD.TH.PV	FAM.FT.AM.LAVM	Ventromedial Amygdaloid Nucleus	nucleus-nucleus	Oculomotor decision-making (AMYG -> Thalamus, abstract)
		FAM.FT.SEP.LT	Lateral Septal Nucleus	nucleus-nucleus-gaba	(unknown reference)
	NDM.NC.AL.VMPFC	FAM.FT.SEP.DBB	Diagonal Band of Broca	nucleus-neocortex-gaba	(unknown reference)
FMM	NDM.NC.AL.DMPFC	FMM.FT.HC.CA1P	Proximal CA1 of Hippocampus	allocortex-neocortex	Gating of medial prefrontal activity by the entorhinal cortex (HC -> MPFC, abstract)
	NDM.NC.AL.VMPFC	FMM.FT.HC.CA1D	Distal CA1 of Hippocampus	allocortex-neocortex	Gating of medial prefrontal activity by the entorhinal cortex (HC -> MPFC, abstract)
LMC	NDM.FD.TH.PV	LMC.MM.PAG	Periaqueductal Gray Matter	nucleus-nucleus-ENK	(unknown reference)
		LMC.MM.RP.DRN	Dorsal Raphe Nucleus	nucleus-nucleus-5HT	(unknown reference)
LPC	NDM.FD.TH.SM	LPC.SC.PH.LMG	Lower Marginal Nucleus	nucleus-nucleus	Afferent pain pathways (SC -> Thalamus, abstract)
		LPC.SC.PH.UMG	Upper Marginal Nucleus	nucleus-nucleus	Afferent pain pathways (SC -> Thalamus, abstract)

External Outbound Region Connections:

Target Area	Local Region	Target Region	Target Name	Type	Reference
Cortical
NCP	NDM.NC.AL.IPG	NCP.NC.AL.SGCG	Subgenual Cingulate Cortex	neocortex-neocortex	Regulation of Social Brain (IFG -> SGC)
NDM	NDM.FD.TH.PV	NDM.NC.AL.ROFCS	Sulcal Rostral Orbitofrontal Cortex	nucleus-neocortex	Saccadic Vision (Thalamus -> FrontalCortex, abstract)
	NDM.NC.AL.DMPFC	NDM.NC.AL.DACG	Dorsal Anterior Cingulate Area	neocortex-neocortex	(unknown reference)
	NDM.NC.AL.IPG	NDM.NC.AL.DLPFCL	Lateral Mid-Dorsolateral Prefrontal Cortex	neocortex-neocortex	Directed Effort Network (fPole -> DLPFC, abstract)
		NDM.NC.AL.VACG	Ventral Anterior Cingulate Area	neocortex-neocortex	Directed Effort Network (fPole -> vACC)
Subcortical
FAM	NDM.FD.TH.PV	FAM.FT.BNST	Bed Nucleus of Stria Terminalis	nucleus-nucleus	(unknown reference)
	NDM.NC.AL.DMPFC	FAM.FT.AM.ITC	Intercalated Amygdaloid Nuclei	neocortex-nucleus	(unknown reference)
	NDM.NC.AL.VMPFC	FAM.FT.AM.ITC	Intercalated Amygdaloid Nuclei	neocortex-nucleus	(unknown reference)
		FAM.FT.AM.LADL	Dorsolateral Amygdaloid Nucleus	neocortex-nucleus	(unknown reference)
FEC	NDM.FD.TH.PV	FEC.FT.ACC.CORE	Nucleus Accumbens Core	nucleus-nucleus	(unknown reference)
FMM	NDM.FD.TH.PV	FMM.NC.PH.LEC	Lateral Entorhinal Cortex	nucleus-neocortex	Contributions of Diencephalon to Recognition Memory (MID -> EC, abstract)
		FMM.NC.PH.PER	Perirhinal Cortex	nucleus-neocortex	Contributions of Diencephalon to Recognition Memory (MID -> Perirhinal, abstract)
LAC	NDM.FD.TH.PV	LAC.FD.HT.MPO	Median Preoptic Nucleus	nucleus-nucleus	(unknown reference)
		LAC.FD.HT.SCN	Suprachiasmatic Nucleus	nucleus-nucleus	(unknown reference)

Motivational Responses

Component ID	Component Name	Type	Service	Function	Comments
NDM.NC.AL.DMCG	Dorsal Medial Cingulate Area	cortex, BA 32	NPU	Rational Thought Processes	Anticipate and detect targets, indicate novelty, influence motor responses, encode reward values, and signal errors, motor, attentional and cognitive functions; BA32-caudal
NDM.NC.AL.PGCG	Pregenual Cingulate Cortex	cortex, BA 33	NPU	Sensation of Emotion	Storage of emotional memory, emotions, mood and autonomic functions
NDM.NC.AL.VMCG	Ventral Medial Cingulate Area	cortex, BA 24	NPU	Response Selection	BA24-caudal

Internal Region Connections:

• no connections

External Inbound Region Connections:

• no connections

External Outbound Region Connections:

• no connections

Unimodal Control

Component ID	Component Name	Type	Service	Function	Comments
NDM.NC.AL.DACG	Dorsal Anterior Cingulate Area	cortex, BA 32	NPU	Rational Thought Processes	Anticipate and detect targets, indicate novelty, influence motor responses, encode reward values, and signal errors, motor, attentional and cognitive functions; BA32-rostral
NDM.NC.AL.VACG	Ventral Anterior Cingulate Area	cortex, BA 24	NPU	Seat of Free Will	motor, attentional and cognitive functions; BA24-rostral

Internal Region Connections:

Source Region	Target Region	Type	Reference
NDM.NC.AL.DACG	NDM.NC.AL.VACG	neocortex-neocortex	Principal Connections of Hippocampus (DorsalCingulate -> VentralCingulate)

External Inbound Region Connections:

Source Area	Local Region	Source Region	Source Name	Type	Reference
Cortical
NCP	NDM.NC.AL.DACG	NCP.FD.TH.LI	Limitans Nucleus of Thalamus	nucleus-neocortex	Afferent pain pathways (Thalamus -> ACC, abstract)
		NCP.NC.AL.SGCG	Subgenual Cingulate Cortex	neocortex-neocortex	Regulation of Social Brain (SGC -> DACC)
		NCP.NC.INS.PPC	Peripaleocortical Claustral	neocortex-neocortex	Amygdalar disruption of prefrontal cortex (INS -> ACG, abstract)
	NDM.NC.AL.VACG	NCP.FD.TH.AM	Anteromedial Nucleus	nucleus-neocortex	Saccadic Vision (Thalamus -> FrontalCortex, abstract)
		NCP.NC.AL.SGCG	Subgenual Cingulate Cortex	neocortex-neocortex	Regulation of Social Brain (SGC -> VACC)
		NCP.NC.INS.AIC	Anterior Insular Cortex	neocortex-neocortex	Amygdalar disruption of prefrontal cortex (INS -> ACG, abstract)
NDM	NDM.NC.AL.DACG	NDM.NC.AL.DLPFCR	Rostral Mid-Dorsolateral Prefrontal Cortex	neocortex-neocortex	Prefrontal Cortex (PFC) in emotional behavior (LPFC -> ACG, abstract)
		NDM.NC.AL.DMPFC	Dorsomedial Prefrontal Cortex	neocortex-neocortex	(unknown reference)
		NDM.NC.AL.ROFCR	Most Rostral Orbitofrontal Cortex	neocortex-neocortex	Role for serotonin in moral behavior (OMPFC -> ACG, abstract)
	NDM.NC.AL.VACG	NDM.NC.AL.FPC	Lateral Frontopolar Cortex	neocortex-neocortex	Role for serotonin in moral behavior (OMPFC -> ACG, abstract)
		NDM.NC.AL.IPG	Inferior Prefrontal Gyrus	neocortex-neocortex	Directed Effort Network (fPole -> vACC)
NMA	NDM.NC.AL.DACG	NMA.FD.TH.MDL	Lateral Mediodorsal Nucleus of Thalamus	nucleus-neocortex	Saccadic Vision (Thalamus -> FrontalCortex, abstract)
NPE	NDM.NC.AL.DACG	NPE.NC.IPL.MST	Medial Superior Temporal Area	neocortex-neocortex	Global visual system (ParietalCortex -> FrontalCortex, abstract)
		NPE.NC.SPL.PF	Rostral Precuneus	neocortex-neocortex	Global visual system (ParietalCortex -> FrontalCortex, abstract)
NSA	NDM.NC.AL.DACG	NSA.NC.TTG.A2	Auditory Association Area	neocortex-neocortex	Directed Effort Network (ACA -> dACC)
Subcortical
FAM	NDM.NC.AL.DACG	FAM.FT.AM.AB	Accessory Basal Amygdaloid Nucleus	nucleus-neocortex	Amygdalar disruption of prefrontal cortex (AM -> ACG, abstract)
	NDM.NC.AL.VACG	FAM.FT.AM.AB	Accessory Basal Amygdaloid Nucleus	nucleus-neocortex	Amygdalar disruption of prefrontal cortex (AM -> ACG, abstract)
FMM	NDM.NC.AL.DACG	FMM.FD.TH.LD	Lateral Dorsal Nucleus of Thalamus	nucleus-neocortex	Thalamocortical relationships (LD -> pLD, abstract)
LMC	NDM.NC.AL.DACG	LMC.MM.VTA	Ventral Tegmental Area	nucleus-neocortex-DA	(unknown reference)

External Outbound Region Connections:

Target Area	Local Region	Target Region	Target Name	Type	Reference
Cortical
NCP	NDM.NC.AL.DACG	NCP.NC.MPL.PSCG	Posterior Cingulate Cortex	neocortex-neocortex	Global visual system (FrontalCortex -> ParietalCortex, abstract)
	NDM.NC.AL.VACG	NCP.NC.MPL.PSCG	Posterior Cingulate Cortex	neocortex-neocortex	Principal Connections of Hippocampus (VentralCingulate -> PosteriorCingulate)
NDM	NDM.NC.AL.VACG	NDM.NC.AL.DLPFCR	Rostral Mid-Dorsolateral Prefrontal Cortex	neocortex-neocortex	Role for serotonin in moral behavior (ACG -> LPFC, abstract)
NMA	NDM.NC.AL.DACG	NMA.NC.PMC.F7	Dorsal Rostral Premotor Cortex	neocortex-neocortex	(unknown reference)
	NDM.NC.AL.VACG	NMA.NC.PMC.F2	Dorsal Caudal Premotor Cortex	neocortex-neocortex	(unknown reference)
Subcortical
FAM	NDM.NC.AL.DACG	FAM.FT.AM.BP	Parvicellular Basal Amygdaloid Nucleus	neocortex-nucleus	Role for serotonin in moral behavior (ACG -> AMY, abstract)
	NDM.NC.AL.VACG	FAM.FT.AM.BP	Parvicellular Basal Amygdaloid Nucleus	neocortex-nucleus	Role for serotonin in moral behavior (ACG -> AMY, abstract)
FEC	NDM.NC.AL.DACG	FEC.FD.STN.CD	Subthalamic Nucleus Caudal	neocortex-nucleus	Functional subdivisions of the subthalamic nucleus (ACG -> STN, abstract)
		FEC.FT.CN.HD	Caudate Nucleus Head	neocortex-nucleus	Global visual system (FrontalCortex -> BGA, abstract)
	NDM.NC.AL.VACG	FEC.FT.ACC.SH	Nucleus Accumbens Shell	neocortex-nucleus	Global visual system (FrontalCortex -> BGA, abstract)
		FEC.FT.CN.BD	Caudate Nucleus Body	neocortex-nucleus	Global visual system (FrontalCortex -> BGA, abstract)
		FEC.FT.PU.VT	Ventral Putamen	neocortex-nucleus	Global visual system (FrontalCortex -> BGA, abstract)
LLC	NDM.NC.AL.VACG	LLC.HT.PRF.RTMG	Pontine Reticulotegmental Nucleus	neocortex-nucleus	Motor neurons control (CTX -> PRF, abstract)
		LLC.MM.RD	Red Nucleus	neocortex-nucleus	Cerebellum functional divisions (CTX -> RD, abstract)
LMC	NDM.NC.AL.VACG	LMC.HT.LC	Locus Coeruleus	neocortex-nucleus	(unknown reference)

Thirdparty Circuits

(generated)

• Regulation of Social Brain - see Reference

map: AMG=Amygdala,FAM.FT.AM, Caud=Caudate Nucleus,FEC.FT.CN (Caudate Nucleus Head (FEC.FT.CN.HD), Caudate Nucleus Body (FEC.FT.CN.BD), Caudate Nucleus Tail (FEC.FT.CN.TL)), DACC=Dorsal Anterior Cingulate Area,NDM.NC.AL.DACG, DLPFC=Mid-Dorsolateral Prefrontal Cortex,NDM.NC.AL.DLPFC (Rostral Mid-Dorsolateral Prefrontal Cortex (NDM.NC.AL.DLPFCR), Lateral Mid-Dorsolateral Prefrontal Cortex (NDM.NC.AL.DLPFCL)), Hipp=Hippocampus,FMM.FT.HC (Dentate Gyrus (FMM.FT.HC.DG), Proximal CA1 of Hippocampus (FMM.FT.HC.CA1P), Middle CA1 of Hippocampus (FMM.FT.HC.CA1M), Distal CA1 of Hippocampus (FMM.FT.HC.CA1D), Dorsolateral Cornu Ammonis of Hippocampus (FMM.FT.HC.CA2), Proximal CA3 of Hippocampus (FMM.FT.HC.CA3P), Middle CA3 of Hippocampus (FMM.FT.HC.CA3M), Distal CA3 of Hippocampus (FMM.FT.HC.CA3D)), IFG=Inferior Prefrontal Gyrus,NDM.NC.AL.IPG, LSN=Lateral Spinal Nucleus,LAC.SC.LH.LSN, MPFC=Orbitofrontal Cortex,NC.AL.OPFC (Lateral Frontopolar Cortex (NDM.NC.AL.FPC), Most Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCR), Sulcal Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCS), Medial Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCM), Lateral Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCL)), NACC=Accumbens Nucleus,FEC.FT.ACC (Nucleus Accumbens Core (FEC.FT.ACC.CORE), Nucleus Accumbens Shell (FEC.FT.ACC.SH)), OFC=Orbitofrontal Cortex,NC.AL.OPFC (Lateral Frontopolar Cortex (NDM.NC.AL.FPC), Most Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCR), Sulcal Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCS), Medial Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCM), Lateral Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCL)), PhippG=Entorhinal Cortex,FMM.NC.PH.ET (Lateral Entorhinal Cortex (FMM.NC.PH.LEC), Medial Entorhinal Cortex (FMM.NC.PH.MEC)), Put=Dorsal Putamen,FEC.FT.DPU (Dorsal Putamen Lateral (FEC.FT.PU.LT), Dorsal Putamen Medial (FEC.FT.PU.MED)), SGC=Subgenual Cingulate Cortex,NCP.NC.AL.SGCG, SN=Substantia Nigra,FEC.FT.SN (Substantia Nigra Pars Compacta Lateral (FEC.FT.SNC.LT), Substantia Nigra Pars Compacta Medial (FEC.FT.SNC.MED), Substantia Nigra Pars Reticulata Dorsolateral (FEC.FT.SNR.DL), Substantia Nigra Pars Reticulata Rostromedial (FEC.FT.SNR.RM), Substantia Nigra Pars Reticulata Ventrolateral (FEC.FT.SNR.VL), Substantia Nigra Pars Reticulata Medial (FEC.FT.SNR.MED)), VACC=Ventral Anterior Cingulate Area,NDM.NC.AL.VACG, VTA=Ventral Tegmental Area,LMC.MM.VTA, VentPal=Ventral Pallidum,FEC.FT.VP (Ventral Pallidum Dorsolateral (FEC.FT.VP.DL), Ventral Pallidum Ventromedial (FEC.FT.VP.VM))

• Directed Effort Network - see Reference

map: AC22=Wernicke's area A4,NSA.NC.STG.A4, ACA=Auditory Association Area,NSA.NC.TTG.A2, AM=Amygdala,FAM.FT.AM, DLPFC=Mid-Dorsolateral Prefrontal Cortex,NDM.NC.AL.DLPFC (Rostral Mid-Dorsolateral Prefrontal Cortex (NDM.NC.AL.DLPFCR), Lateral Mid-Dorsolateral Prefrontal Cortex (NDM.NC.AL.DLPFCL)), HC=Hippocampus,FMM.FT.HC (Dentate Gyrus (FMM.FT.HC.DG), Proximal CA1 of Hippocampus (FMM.FT.HC.CA1P), Middle CA1 of Hippocampus (FMM.FT.HC.CA1M), Distal CA1 of Hippocampus (FMM.FT.HC.CA1D), Dorsolateral Cornu Ammonis of Hippocampus (FMM.FT.HC.CA2), Proximal CA3 of Hippocampus (FMM.FT.HC.CA3P), Middle CA3 of Hippocampus (FMM.FT.HC.CA3M), Distal CA3 of Hippocampus (FMM.FT.HC.CA3D)), Insula=Insular Cortex,NC.INS, OPFC=Orbitofrontal Cortex,NC.AL.OPFC (Lateral Frontopolar Cortex (NDM.NC.AL.FPC), Most Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCR), Sulcal Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCS), Medial Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCM), Lateral Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCL)), PPC=Inferior Parietal Lobule,NC.IPL, dACC=Dorsal Anterior Cingulate Area,NDM.NC.AL.DACG, fPole=Inferior Prefrontal Gyrus,NDM.NC.AL.IPG, tPole=Temporopolar Cortex,NCP.NC.TPC, vACC=Ventral Anterior Cingulate Area,NDM.NC.AL.VACG

• Principal Connections of Hippocampus - see Reference

map: AM=Amygdala,FAM.FT.AM, AN=Anterior Nucleus of Thalamus,FD.TH.AN (Anteromedial Nucleus (NCP.FD.TH.AM), Anteroventral Nucleus (FMM.FD.TH.AV), Anterodorsal Nucleus (FMM.FD.TH.AD)), DG=Dentate Gyrus,FMM.FT.HC.DG, DorsalCingulate=Dorsal Anterior Cingulate Area,NDM.NC.AL.DACG, EC=Entorhinal Cortex,FMM.NC.PH.ET (Lateral Entorhinal Cortex (FMM.NC.PH.LEC), Medial Entorhinal Cortex (FMM.NC.PH.MEC)), HC=Subiculum,FMM.FT.HF.SUB (Proximal Subiculum (FMM.FT.HF.SUBP), Middle Subiculum (FMM.FT.HF.SUBM), Distal Subiculum (FMM.FT.HF.SUBD)), MB=Medial Mammillary Nucleus,FMM.FD.MB.MMB, PosteriorCingulate=Posterior Cingulate Cortex,NCP.NC.MPL.PSCG, SEP=Septal Nuclei,FAM.FT.SEP, SUB=Subiculum,FMM.FT.HF.SUB (Proximal Subiculum (FMM.FT.HF.SUBP), Middle Subiculum (FMM.FT.HF.SUBM), Distal Subiculum (FMM.FT.HF.SUBD)), VentralCingulate=Ventral Anterior Cingulate Area,NDM.NC.AL.VACG

• Fear regulation - see Reference

map: B=Basal Amygdaloid Nucleus,FAM.FT.AM.B (Parvicellular Basal Amygdaloid Nucleus (FAM.FT.AM.BP), Magnocellular Basal Amygdaloid Nucleus (FAM.FT.AM.BM)), CE=Central Amygdala,FAM.FT.AM.CEA (Central Amygdaloid Nucleus, capsular subdivision (FAM.FT.AM.CEC), Central Amygdaloid Nucleus, lateral subdivision (FAM.FT.AM.CEL), Medial Central Amygdaloid Nucleus (FAM.FT.AM.CEM)), Hippocampus=Hippocampus,FMM.FT.HC (Dentate Gyrus (FMM.FT.HC.DG), Proximal CA1 of Hippocampus (FMM.FT.HC.CA1P), Middle CA1 of Hippocampus (FMM.FT.HC.CA1M), Distal CA1 of Hippocampus (FMM.FT.HC.CA1D), Dorsolateral Cornu Ammonis of Hippocampus (FMM.FT.HC.CA2), Proximal CA3 of Hippocampus (FMM.FT.HC.CA3P), Middle CA3 of Hippocampus (FMM.FT.HC.CA3M), Distal CA3 of Hippocampus (FMM.FT.HC.CA3D)), Hypothalamus=Hypothalamus,FD.HT, ITC=Intercalated Amygdaloid Nuclei,FAM.FT.AM.ITC, LA=Lateral Amygdaloid Nucleus,FAM.FT.AM.LA (Dorsolateral Amygdaloid Nucleus (FAM.FT.AM.LADL), Ventrolateral Amygdaloid Nucleus (FAM.FT.AM.LAVL), Ventromedial Amygdaloid Nucleus (FAM.FT.AM.LAVM)), Striatum=Striatum,FEC.FT.ST (Nucleus Accumbens Core (FEC.FT.ACC.CORE), Nucleus Accumbens Shell (FEC.FT.ACC.SH), Ventral Putamen (FEC.FT.PU.VT), Caudate Nucleus Head (FEC.FT.CN.HD), Caudate Nucleus Body (FEC.FT.CN.BD), Caudate Nucleus Tail (FEC.FT.CN.TL), Dorsal Putamen Lateral (FEC.FT.PU.LT), Dorsal Putamen Medial (FEC.FT.PU.MED)), dlPFC=Mid-Dorsolateral Prefrontal Cortex,NDM.NC.AL.DLPFC (Rostral Mid-Dorsolateral Prefrontal Cortex (NDM.NC.AL.DLPFCR), Lateral Mid-Dorsolateral Prefrontal Cortex (NDM.NC.AL.DLPFCL)), vmPFC=Ventromedial Prefrontal Cortex,NDM.NC.AL.VMPFC

• Vocal Control - see Reference

map: A1=Primary Auditory Cortex,NSA.NC.TTG.A1, Broca=Broca's Area,NPE.NC.PFC.BRA (Broca's Area Pars Opercularis (NPE.NC.BRA.PO), Broca's Area Pars Triangularis (NPE.NC.BRA.PT)), M2=Supplementary Motor Cortex,NMA.NC.SMC, MotorV=Trigeminal Motor Nucleus,LPC.HT.TRM, MotorVII=Facial Motor Nucleus,LPC.HT.FCM, NucleusAmbiguus=Ambiguus Nucleus,LPC.HL.AMB, NucleusXII=Hypoglossal Motor Nucleus,LPC.HL.HYG, Premotor24=Ventral Anterior Cingulate Area,NDM.NC.AL.VACG, RF=Pontine Reticular Formation,HT.RF, Wernike=Wernicke's area A4,NSA.NC.STG.A4

• Language-Related Regions - see Reference

map: BA44=Broca's Area,NPE.NC.PFC.BRA (Broca's Area Pars Opercularis (NPE.NC.BRA.PO), Broca's Area Pars Triangularis (NPE.NC.BRA.PT)), BA45=Broca's Area,NPE.NC.PFC.BRA (Broca's Area Pars Opercularis (NPE.NC.BRA.PO), Broca's Area Pars Triangularis (NPE.NC.BRA.PT)), IFG=Broca's Area,NPE.NC.PFC.BRA (Broca's Area Pars Opercularis (NPE.NC.BRA.PO), Broca's Area Pars Triangularis (NPE.NC.BRA.PT)), MTG21=Preoccipital Inferotemporal Area,NSA.NC.IT.TEO, PMC=Premotor Cortex,NC.PMC, STG22a=Wernicke's area A3,NSA.NC.STG.A3, STG22b=Wernicke's area A4,NSA.NC.STG.A4, TC=Temporopolar Cortex,NCP.NC.TPC, pSTC=Wernicke's area A4,NSA.NC.STG.A4, vIFC=Inferior Prefrontal Gyrus,NDM.NC.AL.IPG

• Pathways of Reward Circuit - see Reference

map: Amy=Amygdala,FAM.FT.AM, dACC=Dorsal Anterior Cingulate Area,NDM.NC.AL.DACG

• Depression - see Reference

map: dACC=Dorsal Anterior Cingulate Area,NDM.NC.AL.DACG

• Dorsal midline thalamus - see Reference

map: PT=Paratenial Nucleus of Thalamus,FAM.FD.TH.PT, PVT=Paraventricular Nucleus of Thalamus,NDM.FD.TH.PV

• Medial prefrontal network - see Reference

map: BNST=Bed Nucleus of Stria Terminalis,FAM.FT.BNST, MPFC=Orbitofrontal Cortex,NC.AL.OPFC (Lateral Frontopolar Cortex (NDM.NC.AL.FPC), Most Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCR), Sulcal Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCS), Medial Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCM), Lateral Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCL)), NACC=Accumbens Nucleus,FEC.FT.ACC (Nucleus Accumbens Core (FEC.FT.ACC.CORE), Nucleus Accumbens Shell (FEC.FT.ACC.SH)), PCG=Posterior Cingulate Cortex,NCP.NC.MPL.PSCG, PH=Parahippocampal Lobe,NC.LOBE.PH (Lateral Entorhinal Cortex (FMM.NC.PH.LEC), Medial Entorhinal Cortex (FMM.NC.PH.MEC), Perirhinal Cortex (FMM.NC.PH.PER), Piriform Cortex (NSA.NC.PH.PIR), Prepyriform Cortex (NSA.NC.PH.PRP), Presubiculum (FMM.NC.PH.PRS), Postsubiculum (FMM.NC.PH.POS), Parasubiculum (FMM.NC.PH.PAS), Postrhinal Cortex (FMM.NC.PH.POR)), RSP=Retrosplenial Cortex,NCP.NC.MPL.RSC, RostralCtx=Temporopolar Cortex,NCP.NC.TPC, TH.MD=Mediodorsal Nucleus of Thalamus,FD.TH.MD (Medial Mediodorsal Nucleus of Thalamus (NDM.FD.TH.MDM), Central Mediodorsal Nucleus of Thalamus (NCP.FD.TH.MDC), Lateral Mediodorsal Nucleus of Thalamus (NMA.FD.TH.MDL)), TH.PV=Paraventricular Nucleus of Thalamus,NDM.FD.TH.PV, VPAL=Ventral Pallidum,FEC.FT.VP (Ventral Pallidum Dorsolateral (FEC.FT.VP.DL), Ventral Pallidum Ventromedial (FEC.FT.VP.VM))

References

(generated)

• http://brmlab.cz/project/brain_hacking/tdcs/pfc
• http://www.frontiersin.org/Human_Neuroscience/10.3389/fnhum.2012.00184/full
• http://highered.mcgraw-hill.com/sites/dl/free/0071402357/156721/figure350_1.html
• https://brmlab.cz/project/brain_hacking/tdcs/pfc
• http://www.frontiersin.org/neuroanatomy/10.3389/fnana.2011.00034/full
• http://www.sciencedirect.com/science/article/pii/S1364661312002823
• http://www.nature.com/npp/journal/v35/n1/fig_tab/npp2009129f1.html
• http://contemplativemind.wordpress.com/category/peer-reviewed-journal-articles/
• http://www.sciencedirect.com/science/article/pii/S0149763415002055
• http://www.nature.com/npp/journal/v35/n1/fig_tab/npp2009104f10.html