Forebrain Affective Motivations Area

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Local Circuits

(generated)

Acquisition of Avoidance Responses

unavailable

|| *Component ID* || *Component Name* || *Type* || *Service* || *Function* || *Comments* || || FAM.FD.LHB.LT || Lateral Habenula Lateral Part || nucleus || FAU || Encoding negative feedback, direct, Pallidal || || || FAM.FD.LHB.MED || Lateral Habenula Medial Part || nucleus || FAU || Encoding negative feedback, direct, Septal || ||

Internal Region Connections:*
no connections

External Inbound Region Connections:*

|| *Source Area* || *Local Region* || *Source Region* || *Source Name* || *Type* || *Reference* || || Subcortical || || || || || || || FAM || BrainRegionFAM_FD_LHB_MED FAM.FD.LHB.MED || BrainRegionFAM_FD_MHB FAM.FD.MHB || Medial Habenula || nucleus-nucleus || (unknown reference) || || || || FAM.HP.NI || Incertus Nucleus || nucleus-nucleus-gaba || (unknown reference) || || FEC || BrainRegionFAM_FD_LHB_LT FAM.FD.LHB.LT || BrainRegionFEC_FT_GPI_DS FEC.FT.GPI.DS || Globus Pallidus Internal Dorsal || nucleus-nucleus-gaba || [Habenula Connections (GPi -> LHb, abstract)] || || || FAM.FD.LHB.MED || BrainRegionFEC_FT_VP_VM FEC.FT.VP.VM || Ventral Pallidum Ventromedial || nucleus-nucleus-gaba || (unknown reference) || || LAC || BrainRegionFAM_FD_LHB_LT FAM.FD.LHB.LT || BrainRegionLAC_FD_HT_LTN LAC.FD.HT.LTN || Lateral Hypothalamic Nucleus || nucleus-nucleus || [Habenula Connections (LH -> LHb, abstract)] || || || || LAC.FD.HT.PO || Preoptic Nucleus || nucleus-nucleus || [Habenula Connections (LPO -> LHb, abstract)] || || LMC || BrainRegionFAM_FD_LHB_LT FAM.FD.LHB.LT || BrainRegionLMC_MM_RF_SUC LMC.MM.RF.SUC || Superior Central Raphe Nucleus || nucleus-nucleus-5HT || (unknown reference) ||

External Outbound Region Connections:*

|| *Target Area* || *Local Region* || *Target Region* || *Target Name* || *Type* || *Reference* || || Subcortical || || || || || || || FAM || BrainRegionFAM_FD_LHB_LT FAM.FD.LHB.LT || BrainRegionFAM_HP_PPN_RMTG FAM.HP.PPN.RMTG || Rostromedial Tegmental Nucleus || nucleus-nucleus || [Amygdala and its network (LHB -> RMTG, abstract)] || || FEC || BrainRegionFAM_FD_LHB_MED FAM.FD.LHB.MED || BrainRegionFEC_FT_SNC_LT FEC.FT.SNC.LT || Substantia Nigra Pars Compacta Lateral || nucleus-nucleus || [Habenula Connections (LHb -> SNc, abstract)] || || LMC || BrainRegionFAM_FD_LHB_MED FAM.FD.LHB.MED || BrainRegionLMC_HP_TG_DTG LMC.HP.TG.DTG || Dorsal Tegmental Nucleus || nucleus-nucleus || (unknown reference) || || || || LMC.HP.TG.VTG || Ventral Tegmental Nucleus || nucleus-nucleus || (unknown reference) || || || || LMC.MM.RF.SUC || Superior Central Raphe Nucleus || nucleus-nucleus || [Habenula Connections (LHb -> MR, abstract)] || || || || LMC.MM.RP.DRN || Dorsal Raphe Nucleus || nucleus-nucleus || [Habenula Connections (LHb -> DR, abstract)] ||

Conscious Emotions Control

unavailable

|| *Component ID* || *Component Name* || *Type* || *Service* || *Function* || *Comments* || || FAM.FT.AM.BP || Parvicellular Basal Amygdaloid Nucleus || nucleus || FAU || enhance explicit memories in hippocampus about emotional situations || || || FAM.FT.AM.ITC || Intercalated Amygdaloid Nuclei || nucleus || FAU || inhibit excessive emotional behavior || inhibitory || || FAM.FT.SEP.SF || Septofimbrial Nucleus || nucleus || FAU || afferent to medial habenula, primary input to indirect encoding negative feedback || || || FAM.FT.SEP.TR || Triangular Septal Nucleus || nucleus || FAU || afferent to medial habenula, interpeduncular nucleus || ||

Internal Region Connections:*
no connections

External Inbound Region Connections:*

|| *Source Area* || *Local Region* || *Source Region* || *Source Name* || *Type* || *Reference* || || Cortical || || || || || || || NDM || BrainRegionFAM_FT_AM_BP FAM.FT.AM.BP || BrainRegionNDM_NC_AL_DACG NDM.NC.AL.DACG || Dorsal Anterior Cingulate Area || neocortex-nucleus || [Role for serotonin in moral behavior (ACG -> AMY, abstract)] || || || || NDM.NC.AL.FPC || Lateral Frontopolar Cortex || neocortex-nucleus || (unknown reference) || || || || NDM.NC.AL.VACG || Ventral Anterior Cingulate Area || neocortex-nucleus || [Role for serotonin in moral behavior (ACG -> AMY, abstract)] || || || FAM.FT.AM.ITC || BrainRegionNDM_NC_AL_DMPFC NDM.NC.AL.DMPFC || Dorsomedial Prefrontal Cortex || neocortex-nucleus || (unknown reference) || || Subcortical || || || || || || || FAM || BrainRegionFAM_FT_AM_BP FAM.FT.AM.BP || BrainRegionFAM_FT_AM_LADL FAM.FT.AM.LADL || Dorsolateral Amygdaloid Nucleus || nucleus-nucleus || [Amygdala and its network (LA -> BLN, abstract)] || || || || FAM.FT.AM.LAVL || Ventrolateral Amygdaloid Nucleus || nucleus-nucleus || [Amygdala and its network (LA -> BLN, abstract)] || || || FAM.FT.AM.ITC || BrainRegionFAM_FT_AM_BM FAM.FT.AM.BM || Magnocellular Basal Amygdaloid Nucleus || nucleus-nucleus || (unknown reference) || || || || FAM.FT.AM.LADL || Dorsolateral Amygdaloid Nucleus || nucleus-nucleus || (unknown reference) || || || FAM.FT.SEP.SF || BrainRegionFAM_HP_NI FAM.HP.NI || Incertus Nucleus || nucleus-nucleus-gaba || (unknown reference) || || || FAM.FT.SEP.TR || BrainRegionFAM_HP_NI FAM.HP.NI || Incertus Nucleus || nucleus-nucleus-gaba || (unknown reference) || || FMM || BrainRegionFAM_FT_SEP_SF FAM.FT.SEP.SF || BrainRegionFMM_FT_HC_CA3D FMM.FT.HC.CA3D || Distal CA1 of Hippocampus || allocortex-nucleus || [Cingulate Gyrus (HC -> SEP, abstract)] || || || FAM.FT.SEP.TR || BrainRegionFMM_FT_HF_SUBD FMM.FT.HF.SUBD || Distal Subiculum || allocortex-nucleus || [Medial mammillary nucleus and theta rhythm (HF -> SEP, abstract)] ||

External Outbound Region Connections:*

|| *Target Area* || *Local Region* || *Target Region* || *Target Name* || *Type* || *Reference* || || Subcortical || || || || || || || FAM || BrainRegionFAM_FT_AM_BP FAM.FT.AM.BP || BrainRegionFAM_FT_AM_BM FAM.FT.AM.BM || Magnocellular Basal Amygdaloid Nucleus || nucleus-nucleus || (unknown reference) || || || || FAM.FT.AM.CEM || Medial Central Amygdaloid Nucleus || nucleus-nucleus || [Amygdala and its network (BLN -> CEA, abstract)] || || || FAM.FT.AM.ITC || BrainRegionFAM_FT_AM_CEM FAM.FT.AM.CEM || Medial Central Amygdaloid Nucleus || nucleus-nucleus-gaba || (unknown reference) || || || FAM.FT.SEP.SF || BrainRegionFAM_FD_MHB FAM.FD.MHB || Medial Habenula || nucleus-nucleus-gaba || [Habenula Connections (S -> MHb, abstract)] || || || FAM.FT.SEP.TR || BrainRegionFAM_FD_MHB FAM.FD.MHB || Medial Habenula || nucleus-nucleus-gaba || [Habenula Connections (S -> MHb, abstract)] || || FEC || BrainRegionFAM_FT_AM_BP FAM.FT.AM.BP || BrainRegionFEC_FT_ACC_CORE FEC.FT.ACC.CORE || Nucleus Accumbens Core || nucleus-nucleus || [Amygdala and its network (BLN -> NACC, abstract)] || || FMM || BrainRegionFAM_FT_AM_BP FAM.FT.AM.BP || BrainRegionFMM_NC_PH_LEC FMM.NC.PH.LEC || Lateral Entorhinal Cortex || nucleus-neocortex || [Principal Connections of Hippocampus (AM -> EC, abstract)] || || LMC || BrainRegionFAM_FT_AM_BP FAM.FT.AM.BP || BrainRegionLMC_FT_NBM LMC.FT.NBM || Basal Nucleus of Meynert || nucleus-nucleus || (unknown reference) ||

Conditional Context Sensory Data and Memory Attention

unavailable

|| *Component ID* || *Component Name* || *Type* || *Service* || *Function* || *Comments* || || FAM.FD.TH.PT || Paratenial Nucleus of Thalamus || nucleus || FAU || Gateway for multimodal information to limbic system used in selecting appropriate
responses || Projects to BNST, AM, OMPFC, ET; Direct behavior
toward a particular outcome over a range of
outcomes || || FAM.FT.AM.AB || Accessory Basal Amygdaloid Nucleus || nucleus || FAU || enhance assotiative memory formation || proections to matrix of core of NACC || || FAM.FT.AM.BM || Magnocellular Basal Amygdaloid Nucleus || nucleus || FAU || enhance emotional memories memories in medial prefrontal cortex || || || FAM.FT.AM.COA || Anterior Cortical Amygdaloid Nucleus || nucleus || FAU || olfactory processing - conditional contextual signaling || || || FAM.FT.AM.LADL || Dorsolateral Amygdaloid Nucleus || nucleus || FAU || conditional stimulus input - high-aggregated visual, auditory and somatic,
patterns of perception || LA2 ||

Internal Region Connections:*

|| *Source Region* || *Target Region* || *Type* || *Reference* || || FAM.FT.AM.COA || BrainRegionFAM_FT_AM_AB FAM.FT.AM.AB || nucleus-nucleus || (unknown reference) || || FAM.FT.AM.LADL || BrainRegionFAM_FT_AM_AB FAM.FT.AM.AB || nucleus-nucleus || [Body alarm system (LA -> AB, abstract)] ||

External Inbound Region Connections:*

|| *Source Area* || *Local Region* || *Source Region* || *Source Name* || *Type* || *Reference* || || Cortical || || || || || || || NCP || BrainRegionFAM_FT_AM_BM FAM.FT.AM.BM || BrainRegionNCP_NC_INS_PIC NCP.NC.INS.PIC || Posterior Insular Cortex || neocortex-nucleus || (unknown reference) || || || FAM.FT.AM.LADL || BrainRegionNCP_NC_INS_PPC NCP.NC.INS.PPC || Peripaleocortical Claustral || neocortex-nucleus || (unknown reference) || || NDM || BrainRegionFAM_FT_AM_BM FAM.FT.AM.BM || BrainRegionNDM_NC_AL_FPC NDM.NC.AL.FPC || Lateral Frontopolar Cortex || neocortex-nucleus || (unknown reference) || || NSA || BrainRegionFAM_FT_AM_LADL FAM.FT.AM.LADL || BrainRegionNSA_FD_TH_MGB NSA.FD.TH.MGB || Medial Geniculate Body || nucleus-nucleus || [Amygdalar disruption of prefrontal cortex (TH -> AM, abstract)] || || || || NSA.NC.IT.TE || Inferotemporal Cortex || neocortex-nucleus || [Amygdala and its network (ITC -> LA, abstract)] || || Subcortical || || || || || || || FAM || BrainRegionFAM_FT_AM_AB FAM.FT.AM.AB || BrainRegionFAM_FT_AM_LAVM FAM.FT.AM.LAVM || Ventromedial Amygdaloid Nucleus || nucleus-nucleus || [Body alarm system (LA -> AB, abstract)] || || || FAM.FT.AM.BM || BrainRegionFAM_FT_AM_BP FAM.FT.AM.BP || Parvicellular Basal Amygdaloid Nucleus || nucleus-nucleus || (unknown reference) || || || FAM.FT.AM.LADL || BrainRegionFAM_FT_IPAC_MED FAM.FT.IPAC.MED || Medial Interstitial Anterior Commissural Nucleus || nucleus-nucleus || (unknown reference) || || FMM || BrainRegionFAM_FT_AM_AB FAM.FT.AM.AB || BrainRegionFMM_FT_HF_SUBD FMM.FT.HF.SUBD || Distal Subiculum || allocortex-nucleus || [Simplified model of hippocampal formation anatomy (SUB -> Amyg, abstract)] || || || || FMM.FT.HF.SUBP || Proximal Subiculum || allocortex-nucleus || [Simplified model of hippocampal formation anatomy (SUB -> Amyg, abstract)] || || || || FMM.NC.PH.LEC || Lateral Entorhinal Cortex || neocortex-nucleus || [Simplified model of hippocampal formation anatomy (EC -> Amyg, abstract)] || || LMC || BrainRegionFAM_FT_AM_BM FAM.FT.AM.BM || BrainRegionLMC_FT_NBM LMC.FT.NBM || Basal Nucleus of Meynert || nucleus-nucleus-ACh || (unknown reference) || || LPC || BrainRegionFAM_FT_AM_COA FAM.FT.AM.COA || BrainRegionLPC_FT_MOB LPC.FT.MOB || Main Olfactory Bulb || nucleus-nucleus || (unknown reference) ||

External Outbound Region Connections:*

Express Flight Emotions

unavailable

|| *Component ID* || *Component Name* || *Type* || *Service* || *Function* || *Comments* || || FAM.FT.AM.MEA || Medial Anterior Amygdaloid Nucleus || nucleus || FAU || olfactory processing || || || FAM.FT.AM.MPD || Medial Posteror Dorsal Amygdaloid Nucleus || nucleus || FAU || reproductive behavior || MePD -> HT-MPN || || FAM.FT.AM.MPV || Medial Posteror Ventral Amygdaloid Nucleus || nucleus || FAU || defensive behavior || MePV -> LAC.FD.HT.VM (reproductive+defensive),
LAC.FD.HT.AH (defensive) || || FAM.FT.BNST || Bed Nucleus of Stria Terminalis || nucleus || FAU || Mediate slow longer-lasting responses that accompany sustained threats || Major output from AM to HT, part of extended
amygdala; medial part continues to medial AM,
central part continues to central AM || || FAM.FT.IPAC.MED || Medial Interstitial Anterior Commissural Nucleus || nucleus || FAU || Sharp, acute pain sensation || reciprocate its afferent connections, similar to
medial part of central amygdaloid nucleus;
projections to AM-Ce/BNST components, PB, and SOL
originate chiefly from medial division; strong ACh
projections from caudal IPACm to AM-BL-posterior
and amygdalopiriform transition area || || FAM.FT.SEP.BAC || Bed Nucleus of Anterior Commissure || nucleus || FAU || projection to contralateral HC || ||

Internal Region Connections:*

|| *Source Region* || *Target Region* || *Type* || *Reference* || || FAM.FT.AM.MEA || BrainRegionFAM_FT_AM_MPD FAM.FT.AM.MPD || nucleus-nucleus || (unknown reference) || || || FAM.FT.AM.MPV || nucleus-nucleus || (unknown reference) || || || FAM.FT.BNST || nucleus-nucleus || (unknown reference) || || || FAM.FT.IPAC.MED || nucleus-nucleus || (unknown reference) || || FAM.FT.AM.MPV || BrainRegionFAM_FT_BNST FAM.FT.BNST || nucleus-nucleus-gaba || (unknown reference) || || FAM.FT.BNST || BrainRegionFAM_FT_IPAC_MED FAM.FT.IPAC.MED || nucleus-nucleus || (unknown reference) || || || FAM.FT.SEP.BAC || nucleus-nucleus || (unknown reference) ||

External Inbound Region Connections:*

|| *Source Area* || *Local Region* || *Source Region* || *Source Name* || *Type* || *Reference* || || Cortical || || || || || || || NCP || BrainRegionFAM_FT_BNST FAM.FT.BNST || BrainRegionNCP_NC_AL_SGCG NCP.NC.AL.SGCG || Subgenual Cingulate Cortex || neocortex-nucleus || (unknown reference) || || NSA || BrainRegionFAM_FT_IPAC_MED FAM.FT.IPAC.MED || BrainRegionNSA_NC_PH_PIR NSA.NC.PH.PIR || Piriform Cortex || neocortex-nucleus || (unknown reference) || || Subcortical || || || || || || || FAM || BrainRegionFAM_FT_AM_MEA FAM.FT.AM.MEA || BrainRegionFAM_FT_AM_COP FAM.FT.AM.COP || Posterior Cortical Amygdaloid Nucleus || nucleus-nucleus || (unknown reference) || || || FAM.FT.AM.MPD || BrainRegionFAM_FT_AM_AB FAM.FT.AM.AB || Accessory Basal Amygdaloid Nucleus || nucleus-nucleus || (unknown reference) || || || FAM.FT.BNST || BrainRegionFAM_FD_TH_PT FAM.FD.TH.PT || Paratenial Nucleus of Thalamus || nucleus-nucleus || (unknown reference) || || || || FAM.FT.AM.CEL || Central Amygdaloid Nucleus, lateral subdivision || nucleus-nucleus || (unknown reference) || || LAC || BrainRegionFAM_FT_BNST FAM.FT.BNST || BrainRegionLAC_FD_HT_VM LAC.FD.HT.VM || Ventromedial Hypothalamic Nucleus || nucleus-nucleus || (unknown reference) || || LPC || BrainRegionFAM_FT_AM_MEA FAM.FT.AM.MEA || BrainRegionLPC_FT_AOB LPC.FT.AOB || Accessory Olfactory Bulb || nucleus-nucleus || (unknown reference) || || || FAM.FT.BNST || BrainRegionLPC_FD_TH_PV LPC.FD.TH.PV || Paraventricular Nucleus of Thalamus || nucleus-nucleus || (unknown reference) ||

External Outbound Region Connections:*

|| *Target Area* || *Local Region* || *Target Region* || *Target Name* || *Type* || *Reference* || || Subcortical || || || || || || || FAM || BrainRegionFAM_FT_AM_MEA FAM.FT.AM.MEA || BrainRegionFAM_FT_AM_CEM FAM.FT.AM.CEM || Medial Central Amygdaloid Nucleus || nucleus-nucleus || [Body alarm system (MED -> CE, abstract)] || || || FAM.FT.AM.MPV || BrainRegionFAM_FT_SEP_LT FAM.FT.SEP.LT || Lateral Septal Nucleus || nucleus-nucleus-gaba || (unknown reference) || || || FAM.FT.IPAC.MED || BrainRegionFAM_FT_AM_LADL FAM.FT.AM.LADL || Dorsolateral Amygdaloid Nucleus || nucleus-nucleus || (unknown reference) || || || FAM.FT.SEP.BAC || BrainRegionFAM_FD_MHB FAM.FD.MHB || Medial Habenula || nucleus-nucleus || [Habenula Connections (S -> MHb, abstract)] || || FEC || BrainRegionFAM_FT_BNST FAM.FT.BNST || BrainRegionFEC_FT_SNC_MED FEC.FT.SNC.MED || Substantia Nigra Pars Compacta Medial || nucleus-nucleus || (unknown reference) || || FMM || BrainRegionFAM_FT_AM_MPV FAM.FT.AM.MPV || BrainRegionFMM_FD_TH_RE FMM.FD.TH.RE || Reuniens Nucleus of Thalamus || nucleus-nucleus-gaba || [Oculomotor decision-making (AMYG -> Thalamus, abstract)] || || || FAM.FT.SEP.BAC || BrainRegionFMM_FT_HF_SUBP FMM.FT.HF.SUBP || Proximal Subiculum || nucleus-allocortex || [Medial mammillary nucleus and theta rhythm (SEP -> HF, abstract)] || || LAC || BrainRegionFAM_FT_AM_MEA FAM.FT.AM.MEA || BrainRegionLAC_FD_HT_PO LAC.FD.HT.PO || Preoptic Nucleus || nucleus-nucleus || [Role for serotonin in moral behavior (AMY -> HYP, abstract)] || || || FAM.FT.AM.MPD || BrainRegionLAC_FD_HT_PO LAC.FD.HT.PO || Preoptic Nucleus || nucleus-nucleus-gaba || [Role for serotonin in moral behavior (AMY -> HYP, abstract)] || || || || LAC.FD.HT.PV || Paraventricular Nucleus || nucleus-nucleus-gaba || [Amygdalar disruption of prefrontal cortex (AM -> HT.PV, abstract)] || || || FAM.FT.AM.MPV || BrainRegionLAC_FD_HT_PRM LAC.FD.HT.PRM || Premammillary Nucleus || nucleus-nucleus-gaba || [Amygdalar disruption of prefrontal cortex (AM -> HT.L, abstract)] || || || || LAC.FD.HT.VM || Ventromedial Hypothalamic Nucleus || nucleus-nucleus-gaba || [Role for serotonin in moral behavior (AMY -> HYP, abstract)] || || LMC || BrainRegionFAM_FT_BNST FAM.FT.BNST || BrainRegionLMC_FT_NBM LMC.FT.NBM || Basal Nucleus of Meynert || nucleus-nucleus || (unknown reference) || || || || LMC.HP.LC || Locus Coeruleus || nucleus-nucleus || (unknown reference) || || || || LMC.MM.VTA || Ventral Tegmental Area || nucleus-nucleus || (unknown reference) || || LPC || BrainRegionFAM_FT_IPAC_MED FAM.FT.IPAC.MED || BrainRegionLPC_HM_SOL LPC.HM.SOL || Solitary Nucleus || nucleus-nucleus || (unknown reference) || || || || LPC.HP.PB || Parabrachial Nucleus || nucleus-nucleus || (unknown reference) ||

Express Fight Emotions

unavailable

|| *Component ID* || *Component Name* || *Type* || *Service* || *Function* || *Comments* || || FAM.FT.AM.CEM || Medial Central Amygdaloid Nucleus || nucleus || FAU || mediate behavioral responses, output projections || || || FAM.FT.SEP.SH || Septohippocampal Nucleus || nucleus || FAU || participate in solving conflict between two or more competing goals, defensive
circuit || ||

Internal Region Connections:*
no connections

External Inbound Region Connections:*

|| *Source Area* || *Local Region* || *Source Region* || *Source Name* || *Type* || *Reference* || || Cortical || || || || || || || NDM || BrainRegionFAM_FT_SEP_SH FAM.FT.SEP.SH || BrainRegionNDM_NC_AL_FPC NDM.NC.AL.FPC || Lateral Frontopolar Cortex || neocortex-nucleus || (unknown reference) || || Subcortical || || || || || || || FAM || BrainRegionFAM_FT_AM_CEM FAM.FT.AM.CEM || BrainRegionFAM_FT_AM_AB FAM.FT.AM.AB || Accessory Basal Amygdaloid Nucleus || nucleus-nucleus || [Body alarm system (AB -> CE, abstract)] || || || || FAM.FT.AM.BP || Parvicellular Basal Amygdaloid Nucleus || nucleus-nucleus || [Amygdala and its network (BLN -> CEA, abstract)] || || || || FAM.FT.AM.CEC || Central Amygdaloid Nucleus, capsular subdivision || nucleus-nucleus || (unknown reference) || || || || FAM.FT.AM.CEL || Central Amygdaloid Nucleus, lateral subdivision || nucleus-nucleus || (unknown reference) || || || || FAM.FT.AM.ITC || Intercalated Amygdaloid Nuclei || nucleus-nucleus-gaba || (unknown reference) || || || || FAM.FT.AM.MEA || Medial Anterior Amygdaloid Nucleus || nucleus-nucleus || [Body alarm system (MED -> CE, abstract)] || || FEC || BrainRegionFAM_FT_AM_CEM FAM.FT.AM.CEM || BrainRegionFEC_FT_SNC_MED FEC.FT.SNC.MED || Substantia Nigra Pars Compacta Medial || nucleus-nucleus-DA || (unknown reference) ||

External Outbound Region Connections:*

|| *Target Area* || *Local Region* || *Target Region* || *Target Name* || *Type* || *Reference* || || Subcortical || || || || || || || FAM || BrainRegionFAM_FT_AM_CEM FAM.FT.AM.CEM || BrainRegionFAM_FT_SEP_LT FAM.FT.SEP.LT || Lateral Septal Nucleus || nucleus-nucleus || (unknown reference) || || LAC || BrainRegionFAM_FT_AM_CEM FAM.FT.AM.CEM || BrainRegionLAC_FD_HT_LTN LAC.FD.HT.LTN || Lateral Hypothalamic Nucleus || nucleus-nucleus || [Amygdalar disruption of prefrontal cortex (AM -> HT.L, abstract)] || || || FAM.FT.SEP.SH || BrainRegionLAC_FD_HT_LTN LAC.FD.HT.LTN || Lateral Hypothalamic Nucleus || nucleus-nucleus || [Cingulate Gyrus (SEP -> HT, abstract)] || || LMC || BrainRegionFAM_FT_AM_CEM FAM.FT.AM.CEM || BrainRegionLMC_FT_NBM LMC.FT.NBM || Basal Nucleus of Meynert || nucleus-nucleus || (unknown reference) || || || || LMC.MM.PAG || Periaqueductal Gray Matter || nucleus-nucleus || [Amygdalar disruption of prefrontal cortex (AM -> PAG, abstract)] ||

Solving Fight-Flight Dilemma

unavailable

|| *Component ID* || *Component Name* || *Type* || *Service* || *Function* || *Comments* || || FAM.FT.SEP.LT || Lateral Septal Nucleus || nucleus || FAU || promote active stress coping behavior || ||

Internal Region Connections:*
no connections

External Inbound Region Connections:*

|| *Source Area* || *Local Region* || *Source Region* || *Source Name* || *Type* || *Reference* || || Subcortical || || || || || || || FAM || BrainRegionFAM_FT_SEP_LT FAM.FT.SEP.LT || BrainRegionFAM_FT_AM_CEM FAM.FT.AM.CEM || Medial Central Amygdaloid Nucleus || nucleus-nucleus || (unknown reference) || || || || FAM.FT.AM.MPV || Medial Posteror Ventral Amygdaloid Nucleus || nucleus-nucleus-gaba || (unknown reference) || || LAC || BrainRegionFAM_FT_SEP_LT FAM.FT.SEP.LT || BrainRegionLAC_FD_HT_PN LAC.FD.HT.PN || Posterior Hypothalamic Nucleus || nucleus-nucleus || (unknown reference) || || || || LAC.FD.HT.TBM || Tuberomammillary Nucleus || nucleus-nucleus || (unknown reference) || || LMC || BrainRegionFAM_FT_SEP_LT FAM.FT.SEP.LT || BrainRegionLMC_MM_RF_SUC LMC.MM.RF.SUC || Superior Central Raphe Nucleus || nucleus-nucleus-5HT || (unknown reference) ||

External Outbound Region Connections:*

|| *Target Area* || *Local Region* || *Target Region* || *Target Name* || *Type* || *Reference* || || Subcortical || || || || || || || LAC || BrainRegionFAM_FT_SEP_LT FAM.FT.SEP.LT || BrainRegionLAC_FD_HT_PO LAC.FD.HT.PO || Preoptic Nucleus || nucleus-nucleus-gaba || [Cingulate Gyrus (SEP -> HT, abstract)] || || LPC || BrainRegionFAM_FT_SEP_LT FAM.FT.SEP.LT || BrainRegionLPC_FD_TH_PV LPC.FD.TH.PV || Paraventricular Nucleus of Thalamus || nucleus-nucleus-gaba || (unknown reference) ||

Memory Formation Affective Focus

unavailable

|| *Component ID* || *Component Name* || *Type* || *Service* || *Function* || *Comments* || || FAM.FT.SEP.DBB || Diagonal Band of Broca || nucleus || FAU || involved in generation of theta waves in hippocampus || ACh and GABA; ventral group - from stria terminalis
to/from MFB || || FAM.FT.SEP.MED || Medial Septal Nucleus || nucleus || FAU || affect HC for spatial learning, generation of theta waves || output nucleus; projections from AM and HC overlap;
control theta rythm and exprolatory behavior;
from/to MFB to fornix fimbria ||

Internal Region Connections:*
no connections

External Inbound Region Connections:*

|| *Source Area* || *Local Region* || *Source Region* || *Source Name* || *Type* || *Reference* || || Subcortical || || || || || || || FMM || BrainRegionFAM_FT_SEP_MED FAM.FT.SEP.MED || BrainRegionFMM_FT_HC_CA1D FMM.FT.HC.CA1D || Distal CA1 of Hippocampus || allocortex-nucleus || [Attractor Network in Hippocampus (CA1 -> SEP, abstract)] || || LAC || BrainRegionFAM_FT_SEP_DBB FAM.FT.SEP.DBB || BrainRegionLAC_FD_HT_SUM LAC.FD.HT.SUM || Supramammillary Nucleus || nucleus-nucleus || [Medial mammillary nucleus and theta rhythm (SupraMM -> SEP, abstract)] || || || FAM.FT.SEP.MED || BrainRegionLAC_FD_HT_SUM LAC.FD.HT.SUM || Supramammillary Nucleus || nucleus-nucleus || [Medial mammillary nucleus and theta rhythm (SupraMM -> SEP, abstract)] || || LMC || BrainRegionFAM_FT_SEP_DBB FAM.FT.SEP.DBB || BrainRegionLMC_HP_LC LMC.HP.LC || Locus Coeruleus || nucleus-nucleus-NE || (unknown reference) ||

External Outbound Region Connections:*

|| *Target Area* || *Local Region* || *Target Region* || *Target Name* || *Type* || *Reference* || || Cortical || || || || || || || NCP || BrainRegionFAM_FT_SEP_MED FAM.FT.SEP.MED || BrainRegionNCP_NC_MPL_RSC NCP.NC.MPL.RSC || Retrosplenial Cortex || nucleus-neocortex-ACh || [Medial mammillary nucleus and theta rhythm (SEP -> RSP, abstract)] || || NDM || BrainRegionFAM_FT_SEP_DBB FAM.FT.SEP.DBB || BrainRegionNDM_NC_AL_VMPFC NDM.NC.AL.VMPFC || Ventromedial Prefrontal Cortex || nucleus-neocortex-gaba || (unknown reference) || || || FAM.FT.SEP.MED || BrainRegionNDM_FD_TH_MDM NDM.FD.TH.MDM || Medial Mediodorsal Nucleus of Thalamus || nucleus-nucleus-ACh || [Thalamocortical relationships (s1MD -> MD, abstract)] || || Subcortical || || || || || || || FEC || BrainRegionFAM_FT_SEP_MED FAM.FT.SEP.MED || BrainRegionFEC_FD_TH_PF FEC.FD.TH.PF || Parafascicular Nucleus of Thalamus || nucleus-nucleus-ACh || (unknown reference) || || FMM || BrainRegionFAM_FT_SEP_DBB FAM.FT.SEP.DBB || BrainRegionFMM_FD_MB_MMB FMM.FD.MB.MMB || Medial Mammillary Nucleus || nucleus-nucleus-gaba || [Cingulate Gyrus (SEP -> HT, abstract)] || || || || FMM.FT.HC.CA2 || Dorsolateral Cornu Ammonis of Hippocampus || nucleus-allocortex-gaba || [Medial mammillary nucleus and theta rhythm (SEP -> HF, abstract)] || || || FAM.FT.SEP.MED || BrainRegionFMM_FD_MB_LMB FMM.FD.MB.LMB || Lateral Mammillary Nucleus || nucleus-nucleus-ACh || [Cingulate Gyrus (SEP -> HT, abstract)] || || || || FMM.FD.MB.MMB || Medial Mammillary Nucleus || nucleus-nucleus-gaba || [Cingulate Gyrus (SEP -> HT, abstract)] ||

Reward Emotions Control

unavailable

|| *Component ID* || *Component Name* || *Type* || *Service* || *Function* || *Comments* || || FAM.FD.MHB || Medial Habenula || nucleus || FAU || Encoding negative feedback, indirect || affects VTA, dorsal raphe but via interpeduncular
nucleus || || FAM.FT.EPF || Endopiriform Nucleus || nucleus || FAU || Putative relay of limbic-associated cortical-like areas subserving affective
information || || || FAM.HP.NI || Incertus Nucleus || nucleus || LUS || Behavioural activation and the response to stress || Modulating influences on prefrontal and hippocampal
cortical activity, midline behavior control;
modulatory nucleus; relay from reticularis pontis
oralis nucleus to septo-hippocampal system || || FAM.HP.PPN.IPD || Interpeduncular Nucleus || nucleus || FEU || postural control, voluntary arm and eye movements || Pars compacta, anterior, compact subnucleus, ACh;
unpaired || || FAM.HP.PPN.RMTG || Rostromedial Tegmental Nucleus || nucleus || FEU || locomotion - walking, running || Pars dissipata, anterior, dissipated subnucleus,
GABA ||

Internal Region Connections:*

|| *Source Region* || *Target Region* || *Type* || *Reference* || || FAM.FD.MHB || BrainRegionFAM_HP_PPN_IPD FAM.HP.PPN.IPD || nucleus-nucleus || [Habenula Connections (MHb -> IP)] || || FAM.HP.NI || BrainRegionFAM_FT_EPF FAM.FT.EPF || nucleus-nucleus-gaba || (unknown reference) || || FAM.HP.PPN.RMTG || BrainRegionFAM_HP_PPN_IPD FAM.HP.PPN.IPD || nucleus-nucleus-gaba || (unknown reference) ||

External Inbound Region Connections:*

|| *Source Area* || *Local Region* || *Source Region* || *Source Name* || *Type* || *Reference* || || Cortical || || || || || || || NSA || BrainRegionFAM_FT_EPF FAM.FT.EPF || BrainRegionNSA_NC_PH_PIR NSA.NC.PH.PIR || Piriform Cortex || neocortex-nucleus || [Gustatory sensory system of rat and macaque (PiR -> EnP)] || || Subcortical || || || || || || || FAM || BrainRegionFAM_FD_MHB FAM.FD.MHB || BrainRegionFAM_FT_SEP_BAC FAM.FT.SEP.BAC || Bed Nucleus of Anterior Commissure || nucleus-nucleus || [Habenula Connections (S -> MHb, abstract)] || || || || FAM.FT.SEP.SF || Septofimbrial Nucleus || nucleus-nucleus-gaba || [Habenula Connections (S -> MHb, abstract)] || || || || FAM.FT.SEP.TR || Triangular Septal Nucleus || nucleus-nucleus-gaba || [Habenula Connections (S -> MHb, abstract)] || || || FAM.HP.PPN.RMTG || BrainRegionFAM_FD_LHB_LT FAM.FD.LHB.LT || Lateral Habenula Lateral Part || nucleus-nucleus || [Amygdala and its network (LHB -> RMTG, abstract)] || || FEC || BrainRegionFAM_HP_PPN_IPD FAM.HP.PPN.IPD || BrainRegionFEC_FD_STN_ICD FEC.FD.STN.ICD || Subthalamic Nucleus Internal Caudal || nucleus-nucleus || (unknown reference) || || || || FEC.FT.SNR.MED || Substantia Nigra Pars Reticulata Medial || nucleus-nucleus-gaba || (unknown reference) || || || FAM.HP.PPN.RMTG || BrainRegionFEC_FD_STN_LT FEC.FD.STN.LT || Subthalamic Nucleus Lateral || nucleus-nucleus || (unknown reference) || || LMC || BrainRegionFAM_FD_MHB FAM.FD.MHB || BrainRegionLMC_HP_LC LMC.HP.LC || Locus Coeruleus || nucleus-nucleus-NE || (unknown reference) || || || FAM.HP.PPN.IPD || BrainRegionLMC_HP_TG_LDT LMC.HP.TG.LDT || Laterodorsal Tegmental Nucleus || nucleus-nucleus-ACh || [Head Direction Cell Circuit (DTN -> IPD)] || || LRC || BrainRegionFAM_HP_NI FAM.HP.NI || BrainRegionLRC_HP_PRF_RPO LRC.HP.PRF.RPO || Oral Pontine Reticular Nucleus || nucleus-nucleus || (unknown reference) ||

External Outbound Region Connections:*

|| *Target Area* || *Local Region* || *Target Region* || *Target Name* || *Type* || *Reference* || || Cortical || || || || || || || NCP || BrainRegionFAM_FT_EPF FAM.FT.EPF || BrainRegionNCP_NC_INS_AIC NCP.NC.INS.AIC || Anterior Insular Cortex || nucleus-neocortex || [Gustatory sensory system of rat and macaque (EnP -> Iav, abstract)] || || NSA || BrainRegionFAM_HP_PPN_IPD FAM.HP.PPN.IPD || BrainRegionNSA_FD_LGN NSA.FD.LGN || Lateral Geniculate Nucleus || nucleus-nucleus-ACh || [Geniculate and Extyrageniculate Paths (PPN -> LGN, abstract)] || || Subcortical || || || || || || || FAM || BrainRegionFAM_FD_MHB FAM.FD.MHB || BrainRegionFAM_FD_LHB_MED FAM.FD.LHB.MED || Lateral Habenula Medial Part || nucleus-nucleus || (unknown reference) || || || FAM.HP.NI || BrainRegionFAM_FD_LHB_MED FAM.FD.LHB.MED || Lateral Habenula Medial Part || nucleus-nucleus-gaba || (unknown reference) || || || || FAM.FT.SEP.SF || Septofimbrial Nucleus || nucleus-nucleus-gaba || (unknown reference) || || || || FAM.FT.SEP.TR || Triangular Septal Nucleus || nucleus-nucleus-gaba || (unknown reference) || || FEC || BrainRegionFAM_HP_PPN_IPD FAM.HP.PPN.IPD || BrainRegionFEC_FD_STN_LT FEC.FD.STN.LT || Subthalamic Nucleus Lateral || nucleus-nucleus-ACh || (unknown reference) || || || || FEC.FT.SNC.LT || Substantia Nigra Pars Compacta Lateral || nucleus-nucleus-ACh || (unknown reference) || || FMM || BrainRegionFAM_HP_NI FAM.HP.NI || BrainRegionFMM_NC_PH_PER FMM.NC.PH.PER || Perirhinal Cortex || nucleus-neocortex-gaba || (unknown reference) || || LMC || BrainRegionFAM_HP_PPN_RMTG FAM.HP.PPN.RMTG || BrainRegionLMC_HP_TG_LDT LMC.HP.TG.LDT || Laterodorsal Tegmental Nucleus || nucleus-nucleus-gaba || (unknown reference) || || LRC || BrainRegionFAM_HP_PPN_IPD FAM.HP.PPN.IPD || BrainRegionLRC_MM_SC_INT LRC.MM.SC.INT || Intermediate Superior Colliculus || nucleus-nucleus-ACh || [Geniculate and Extyrageniculate Paths (PPN -> SC, abstract)] || || Target || || || || || || || TEA || BrainRegionFAM_FD_MHB FAM.FD.MHB || BrainRegionTARGET_TEA_ENDOCRINE TARGET.TEA.ENDOCRINE || Endocrine Glands || endocrine-pineal-gland || [Habenula Connections (MHb -> PB)] ||

Fast Unconditional Sensory Data and Association Memory

unavailable

|| *Component ID* || *Component Name* || *Type* || *Service* || *Function* || *Comments* || || FAM.FT.AM.CEC || Central Amygdaloid Nucleus, capsular subdivision || nucleus || FAU || mediate behavioral responses, link to striatal effect || gustatory, somatosensory, visual, auditory, frontal
cortex, perirhinal cortex, ET, SUB -> X ->
HT-dl/cl, CeM || || FAM.FT.AM.CEL || Central Amygdaloid Nucleus, lateral subdivision || nucleus || FAU || mediate behavioral responses, link to gustatory and visceral aspects of
reinforcement || contributions of food prediction and food
presentation || || FAM.FT.AM.COP || Posterior Cortical Amygdaloid Nucleus || nucleus || FAU || olfactory processing - unconditional signaling || || || FAM.FT.AM.LAVL || Ventrolateral Amygdaloid Nucleus || nucleus || FAU || unconditional stimulus input - visual, auditory and somatic, convergence from
thalamus || LA1; LGN, MGBm, PIL || || FAM.FT.AM.LAVM || Ventromedial Amygdaloid Nucleus || nucleus || FAU || conditional and unconditional convergence to affect polymodal memory formation || LA3; projects to ET ||