Difference between revisions of "BrainRegionLMC HT LC"

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<pre style="color: green">Locus Coeruleus</pre>
 
<pre style="color: green">Locus Coeruleus</pre>
 
@@[[Home]] -> [[BiologicalLifeResearch]] -> [[BrainAreaLMC]] -> [[BrainRegionLMC_HT_LC]]
 
@@[[Home]] -> [[BiologicalLifeResearch]] -> [[BrainAreaLMC]] -> [[BrainRegionLMC_HT_LC]]
Line 9: Line 8:
 
* '''Top-down path to region''': Hindbrain Metencephalon -> [[BrainRegionLMC_HT_LC|Locus Coeruleus]] (LMC.HT.LC) (see [[OverallMindMaps|Mind Maps]])
 
* '''Top-down path to region''': Hindbrain Metencephalon -> [[BrainRegionLMC_HT_LC|Locus Coeruleus]] (LMC.HT.LC) (see [[OverallMindMaps|Mind Maps]])
 
* '''Type''': nucleus
 
* '''Type''': nucleus
−
* '''Brain area''': [[BrainAreaLMC|Lower Brain - Modulatory Contol Area]]
+
* '''Quality''': L0
−
* '''Role''': relay
+
* '''Brain area''': [[BrainAreaLMC|Lower Brain - Modulatory Contol Area]] (LMC)
−
* '''Function''': Regulate the intensity of responses to salient stimuli
+
* '''Area circuit''': Norepinephrine - Vigilant Concentration, Stress Hormone, Fight-or-Flight Response (NE)
−
* '''Notes to function''': NE Source, enhance signal-to-noise ratio, suppressing irrelevant stimuli (lateral inhibition); inhibitory nucleus
+
* '''Role''': processor.autonomic
 +
* '''Function''': Regulate the intensity of responses to salient stimuli, arousal and autonomic activity
 +
* '''Notes to function''':  
 +
** NE Source, enhance signal-to-noise ratio, suppressing irrelevant stimuli (lateral inhibition)
 +
**  inhibitory nucleus
 +
**  wakefulness-promoting nucleus, enhancement of alertness, increase in sympathetic activity and a decrease in parasympathetic activity, to all neocortex, medial septal area, medial preoptic area and substantia innominata, central and basal amygdala, dorsal thalamus
 
(generated)
 
(generated)
 
= Components =
 
= Components =
Line 29: Line 33:
  
 
{| class=wikitable width=80%
 
{| class=wikitable width=80%
−
| '''Source Area''' || '''Source Region''' || '''Source Name''' || '''Type''' || '''Reference'''
+
| '''Source Area''' || '''Source Region''' || '''Source Name''' || '''Type''' || '''Role''' || '''Reference'''
 
|-
 
|-
−
| [[BrainAreaFAM|FAM]] || [[BrainRegionFAM_FT_AM_CEM|FAM.FT.AM.CEM]] || Medial Central Amygdaloid Nucleus || excitatory-glu || [http://neuropolitics.org/defaultmay10.asp Amygdalar disruption of prefrontal cortex (AM -> LC, abstract)]
+
| [[BrainAreaFAM|FAM]] || [[BrainRegionFAM_FT_AM_CEM|FAM.FT.AM.CEM]] || Medial Central Amygdaloid Nucleus || excitatory-glu || uncertain ||[http://neuropolitics.org/defaultmay10.asp Amygdalar disruption of prefrontal cortex (AM -> LC, abstract)]
 
|-
 
|-
−
|  || [[BrainRegionFAM_FT_BNST|FAM.FT.BNST]] || Bed Nucleus of Stria Terminalis || excitatory-glu || (unknown reference)
+
|  || [[BrainRegionFAM_FT_BNST|FAM.FT.BNST]] || Bed Nucleus of Stria Terminalis || excitatory-glu || uncertain ||(unknown reference)
 
|-
 
|-
−
| [[BrainAreaLAC|LAC]] || [[BrainRegionLAC_FD_HT_DM|LAC.FD.HT.DM]] || Dorsomedial Hypothalamic Nucleus || excitatory-glu || (unknown reference)
+
| [[BrainAreaLAC|LAC]] || [[BrainRegionLAC_FD_HT_DM|LAC.FD.HT.DM]] || Dorsomedial Hypothalamic Nucleus || excitatory-glu || uncertain ||[http://journal.frontiersin.org/article/10.3389/fnint.2012.00094/full Effect of light on pupil diameter (DMH -> LC)]
 
|-
 
|-
−
|  || [[BrainRegionLAC_FD_HT_TBM|LAC.FD.HT.TBM]] || Tuberomammillary Nucleus || excitatory-glu || (unknown reference)
+
|  || [[BrainRegionLAC_FD_HT_TBM|LAC.FD.HT.TBM]] || Tuberomammillary Nucleus || excitatory-glu || uncertain ||(unknown reference)
 
|-
 
|-
−
| [[BrainAreaLRC|LRC]] || [[BrainRegionLRC_HL_RF_MED|LRC.HL.RF.MED]] || Central Medullary Reticular Nucleus || excitatory-glu || (unknown reference)
+
| [[BrainAreaLRC|LRC]] || [[BrainRegionLRC_HL_RF_MED|LRC.HL.RF.MED]] || Central Medullary Reticular Nucleus || excitatory-glu || uncertain ||(unknown reference)
 
|-
 
|-
−
| [[BrainAreaNDM|NDM]] || [[BrainRegionNDM_NC_AL_VACG|NDM.NC.AL.VACG]] || Ventral Anterior Cingulate Area || excitatory-glu || (unknown reference)
+
| [[BrainAreaNDM|NDM]] || [[BrainRegionNDM_NC_AL_VACG|NDM.NC.AL.VACG]] || Ventral Anterior Cingulate Area || excitatory-glu || uncertain ||(unknown reference)
 
|}
 
|}
  
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{| class=wikitable width=80%
 
{| class=wikitable width=80%
−
| '''Target Area''' || '''Target Region''' || '''Target Name''' || '''Type''' || '''Reference'''
+
| '''Target Area''' || '''Target Region''' || '''Target Name''' || '''Type''' || '''Role''' || '''Reference'''
 
|-
 
|-
−
| [[BrainAreaFAM|FAM]] || [[BrainRegionFAM_FD_LHB_LT|FAM.FD.LHB.LT]] || Lateral Habenula Lateral Part || modulatory-ne || [http://www.nature.com/nrn/journal/v11/n6/fig_tab/nrn2849_F7.html Contribution of nAChR subunits to nicotine withdrawal symptoms (LC -> LHB, abstract)]
+
| [[BrainAreaFAM|FAM]] || [[BrainRegionFAM_FD_LHB_LT|FAM.FD.LHB.LT]] || Lateral Habenula Lateral Part || modulatory-ne || uncertain || [http://www.nature.com/nrn/journal/v11/n6/fig_tab/nrn2849_F7.html Contribution of nAChR subunits to nicotine withdrawal symptoms (LC -> LHB, abstract)]
 
|-
 
|-
−
|  || [[BrainRegionFAM_FD_LHB_MED|FAM.FD.LHB.MED]] || Lateral Habenula Medial Part || modulatory-ne || [http://www.nature.com/nrn/journal/v11/n6/fig_tab/nrn2849_F7.html Contribution of nAChR subunits to nicotine withdrawal symptoms (LC -> LHB, abstract)]
+
|  || [[BrainRegionFAM_FD_LHB_MED|FAM.FD.LHB.MED]] || Lateral Habenula Medial Part || modulatory-ne || uncertain || [http://www.nature.com/nrn/journal/v11/n6/fig_tab/nrn2849_F7.html Contribution of nAChR subunits to nicotine withdrawal symptoms (LC -> LHB, abstract)]
 
|-
 
|-
−
|  || [[BrainRegionFAM_FD_MHB|FAM.FD.MHB]] || Medial Habenula || modulatory-ne || [http://www.nature.com/nrn/journal/v11/n6/fig_tab/nrn2849_F7.html Contribution of nAChR subunits to nicotine withdrawal symptoms (LC -> MHB)]
+
|  || [[BrainRegionFAM_FD_MHB|FAM.FD.MHB]] || Medial Habenula || modulatory-ne || uncertain || [http://www.nature.com/nrn/journal/v11/n6/fig_tab/nrn2849_F7.html Contribution of nAChR subunits to nicotine withdrawal symptoms (LC -> MHB)]
 
|-
 
|-
−
|  || [[BrainRegionFAM_FT_SEP_DBB|FAM.FT.SEP.DBB]] || Diagonal Band of Broca || modulatory-ne || (unknown reference)
+
|  || [[BrainRegionFAM_FT_SEP_DBB|FAM.FT.SEP.DBB]] || Diagonal Band of Broca || modulatory-ne || uncertain || (unknown reference)
 
|-
 
|-
−
| [[BrainAreaFEC|FEC]] || [[BrainRegionFEC_FT_SNC_MED|FEC.FT.SNC.MED]] || Substantia Nigra Pars Compacta Medial || modulatory-ne || (unknown reference)
+
| [[BrainAreaFEC|FEC]] || [[BrainRegionFEC_FT_SNC_MED|FEC.FT.SNC.MED]] || Substantia Nigra Pars Compacta Medial || modulatory-ne || uncertain || (unknown reference)
 
|-
 
|-
−
|  || [[BrainRegionFEC_HT_PPN_IPD|FEC.HT.PPN.IPD]] || Interpeduncular Nucleus || modulatory-ne || [http://www.nature.com/nrn/journal/v11/n6/fig_tab/nrn2849_F7.html Contribution of nAChR subunits to nicotine withdrawal symptoms (LC -> IPN)]
+
|  || [[BrainRegionFEC_HT_TG_IPD|FEC.HT.TG.IPD]] || Interpeduncular Nucleus || modulatory-ne || uncertain || [http://www.nature.com/nrn/journal/v11/n6/fig_tab/nrn2849_F7.html Contribution of nAChR subunits to nicotine withdrawal symptoms (LC -> IPN)]
 
|-
 
|-
−
| [[BrainAreaLAC|LAC]] || [[BrainRegionLAC_FD_HT_PO|LAC.FD.HT.PO]] || Preoptic Nucleus || modulatory-ne || [http://www.nature.com/neuro/journal/v5/n10/fig_tab/nn913_F1.html Simplified NREM sleep-promoting pathway (LC -> VLPO)]
+
| [[BrainAreaLAC|LAC]] || [[BrainRegionLAC_FD_HT_VLPO|LAC.FD.HT.VLPO]] || Ventrolateral Preoptic Nucleus || modulatory-ne || uncertain || [http://www.nature.com/neuro/journal/v5/n10/fig_tab/nn913_F1.html Simplified NREM sleep-promoting pathway (LC -> VLPO)]
 
|-
 
|-
−
|  || [[BrainRegionLAC_SC_IZ_IML|LAC.SC.IZ.IML]] || Intermediolateral Nucleus || modulatory-ne || [http://www.intechopen.com/books/computational-intelligence-in-electromyography-analysis-a-perspective-on-current-applications-and-future-challenges/sphincter-emg-for-diagnosing-multiple-system-atrophy-and-related-disorders Physiology and pathophysiology of lower urinary tract (LC -> IML)]
+
|  || [[BrainRegionLAC_SC_IZ_CSC|LAC.SC.IZ.CSC]] || Ciliospinal Center || modulatory-ne || uncertain || [http://journal.frontiersin.org/article/10.3389/fnint.2012.00094/full Effect of light on pupil diameter (LC -> IML)]
 +
|-
 +
|  || [[BrainRegionLAC_SC_IZ_IML|LAC.SC.IZ.IML]] || Intermediolateral Nucleus || modulatory-ne || uncertain || [http://www.intechopen.com/books/computational-intelligence-in-electromyography-analysis-a-perspective-on-current-applications-and-future-challenges/sphincter-emg-for-diagnosing-multiple-system-atrophy-and-related-disorders Physiology and pathophysiology of lower urinary tract (LC -> IML)]
 
|}
 
|}
  
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(generated)
 
(generated)
  
−
* [http://www.intechopen.com/source/html/40109/media/image1.jpeg Physiology and pathophysiology of lower urinary tract] - see [http://www.intechopen.com/books/computational-intelligence-in-electromyography-analysis-a-perspective-on-current-applications-and-future-challenges/sphincter-emg-for-diagnosing-multiple-system-atrophy-and-related-disorders Reference]
+
* [http://www.frontiersin.org/files/Articles/31465/fnint-06-00094-r2/image_m/fnint-06-00094-g002.jpg Effect of light on pupil diameter] - see [http://journal.frontiersin.org/article/10.3389/fnint.2012.00094/full Reference] (CP.PUPIL-REFLEX)
 +
 
 +
DMH=[[BrainRegionLAC_FD_HT_DM|Dorsomedial Hypothalamic Nucleus,LAC.FD.HT.DM]]
 +
EW=[[BrainRegionLAC_MM_EWN|Edinger-Westphal Nucleus,LAC.MM.EWN]]
 +
EYE=[[BrainRegionTARGET_TSA_EYE|Eye,TARGET.TSA.EYE]]
 +
GC=[[BrainRegionLAC_PN_PSYM_CLG|Ciliary Ganglion,LAC.PN.PSYM.CLG]]
 +
IML=[[BrainRegionLAC_SC_IZ_CSC|Ciliospinal Center,LAC.SC.IZ.CSC]]
 +
LC=[[BrainRegionLMC_HT_LC|Locus Coeruleus,LMC.HT.LC]]
 +
OPN=[[BrainRegionLRC_MM_PT_PON|Pretectal Olivary Nucleus,LRC.MM.PT.PON]]
 +
PVN=[[BrainRegionLAC_FD_HT_PV|Paraventricular Nucleus,LAC.FD.HT.PV]]
 +
RET=[[BrainRegionLPC_FD_RT|Retinal Nucleus,LPC.FD.RT]]
 +
SCG=[[BrainRegionLAC_PN_SYM_SCG|Superior Cervical Ganglion,LAC.PN.SYM.SCG]]
 +
SCN=[[BrainRegionLAC_FD_HT_SCN|Suprachiasmatic Nucleus,LAC.FD.HT.SCN]]
 +
<img src="http://ahuman.org/svn/ahwiki/images/ext/1cde10342c1a8c5667b42d9df87c4f50.jpg" alt=alt="unavailable" style="max-width: 100%;">
 +
 
 +
* [http://www.intechopen.com/source/html/40109/media/image1.jpeg Physiology and pathophysiology of lower urinary tract] - see [http://www.intechopen.com/books/computational-intelligence-in-electromyography-analysis-a-perspective-on-current-applications-and-future-challenges/sphincter-emg-for-diagnosing-multiple-system-atrophy-and-related-disorders Reference] (CM.ONUF)
  
−
<img src="http://www.intechopen.com/source/html/40109/media/image1.jpeg" alt="unavailable">
+
CN=Caudate Nucleus,FEC.FT.CN (see [[BrainCenterFEC_FT_BG|Basal Ganglia]])
 +
DVM=[[BrainRegionLAC_HL_VGN|Vagus Nucleus,LAC.HL.VGN]]
 +
IMG=[[BrainRegionLAC_PN_SYM_IMG|Inferior Mesenteric Ganglion,LAC.PN.SYM.IMG]]
 +
IML=[[BrainRegionLAC_SC_IZ_IML|Intermediolateral Nucleus,LAC.SC.IZ.IML]]
 +
LC=[[BrainRegionLMC_HT_LC|Locus Coeruleus,LMC.HT.LC]]
 +
MPFC=Orbitofrontal Cortex,NC.AL.OPFC (see [[BrainCenterNC_AL_OMPFC|Orbitomedial Prefrontal Cortex]])
 +
MPOA=[[BrainRegionLAC_FD_HT_MPO|Median Preoptic Nucleus,LAC.FD.HT.MPO]]
 +
NBM=[[BrainRegionLMC_FT_NBM|Basal Nucleus of Meynert,LMC.FT.NBM]]
 +
ONF=[[BrainRegionLPC_SC_VH_ONF|Onuf's Nucleus,LPC.SC.VH.ONF]]
 +
PBN=[[BrainRegionLPC_HT_PRF_PB|Parabrachial Nucleus,LPC.HT.PRF.PB]]
 +
PEL=[[BrainRegionLAC_PN_PSYM_PPG|Pelvic Peripheral Ganglion,LAC.PN.PSYM.PPG]]
 +
PU=[[BrainRegionFEC_FT_PU_LT|Dorsal Putamen Lateral,FEC.FT.PU.LT]]
 +
PVN=[[BrainRegionLAC_FD_HT_PV|Paraventricular Nucleus,LAC.FD.HT.PV]]
 +
SNC=[[BrainRegionFEC_FT_SNC_LT|Substantia Nigra Pars Compacta Lateral,FEC.FT.SNC.LT]]
 +
SPS=[[BrainRegionLAC_SC_IZ_SPS|Sacral Parasympathetic Nucleus,LAC.SC.IZ.SPS]]
 +
VTA=[[BrainRegionLMC_MM_VTA|Ventral Tegmental Area,LMC.MM.VTA]]
 +
ZI=[[BrainRegionFEC_FD_STN_CD|Subthalamic Nucleus Caudal,BGA.FD.STN.ZI]]
 +
<img src="http://ahuman.org/svn/ahwiki/images/ext/b3238c9c6efdcfa004931bec8815fc0b.jpeg" alt=alt="unavailable" style="max-width: 100%;">
  
−
* [http://www.nature.com/nrn/journal/v11/n6/images/nrn2849-f7.jpg Contribution of nAChR subunits to nicotine withdrawal symptoms] - see [http://www.nature.com/nrn/journal/v11/n6/fig_tab/nrn2849_F7.html Reference]
+
* [http://www.nature.com/nrn/journal/v11/n6/images/nrn2849-f7.jpg Contribution of nAChR subunits to nicotine withdrawal symptoms] - see [http://www.nature.com/nrn/journal/v11/n6/fig_tab/nrn2849_F7.html Reference] (CF.HB-NICOTINE)
  
−
<img src="http://www.nature.com/nrn/journal/v11/n6/images/nrn2849-f7.jpg" alt="unavailable">
+
IPN=[[BrainRegionFEC_HT_TG_IPD|Interpeduncular Nucleus,FEC.HT.TG.IPD]]
 +
LC=[[BrainRegionLMC_HT_LC|Locus Coeruleus,LMC.HT.LC]]
 +
LHB=Lateral Habenula,FAM.FD.LHB (see [[BrainCenterFAM_FD_HB|Habenula]])
 +
MHB=[[BrainRegionFAM_FD_MHB|Medial Habenula,FAM.FD.MHB]]
 +
<img src="http://ahuman.org/svn/ahwiki/images/ext/5ad8108c823890273a2c96d0dfc8441f.jpg" alt=alt="unavailable" style="max-width: 100%;">
  
−
* [http://www.nature.com/neuro/journal/v5/n10/images/nn913-F1.jpg Simplified NREM sleep-promoting pathway] - see [http://www.nature.com/neuro/journal/v5/n10/fig_tab/nn913_F1.html Reference]
+
* [http://www.nature.com/neuro/journal/v5/n10/images/nn913-F1.jpg Simplified NREM sleep-promoting pathway] - see [http://www.nature.com/neuro/journal/v5/n10/fig_tab/nn913_F1.html Reference] (CL.TBM-PO)
  
−
<img src="http://www.nature.com/neuro/journal/v5/n10/images/nn913-F1.jpg" alt="unavailable">
+
LC=[[BrainRegionLMC_HT_LC|Locus Coeruleus,LMC.HT.LC]]
 +
LDTg=[[BrainRegionLMC_HT_TG_LDT|Laterodorsal Tegmental Nucleus,LMC.HT.TG.LDT]]
 +
TMN=[[BrainRegionLAC_FD_HT_TBM|Tuberomammillary Nucleus,LAC.FD.HT.TBM]]
 +
VLPO=[[BrainRegionLAC_FD_HT_VLPO|Ventrolateral Preoptic Nucleus,LAC.FD.HT.VLPO]]
 +
<img src="http://ahuman.org/svn/ahwiki/images/ext/7d1ab7f45d007c61b6a1b8abadde723d.jpg" alt=alt="unavailable" style="max-width: 100%;">
  
−
* [http://neuropolitics.org/connect-amygdala.jpg Amygdalar disruption of prefrontal cortex] - see [http://neuropolitics.org/defaultmay10.asp Reference]
+
* [http://neuropolitics.org/connect-amygdala.jpg Amygdalar disruption of prefrontal cortex] - see [http://neuropolitics.org/defaultmay10.asp Reference] (CF.AM-DISRUPTION)
  
−
<img src="http://neuropolitics.org/connect-amygdala.jpg" alt="unavailable">
+
ACG=Anterior Cingulate Cortex,NC.AL.ACG (see [[BrainCenterNC_ACG|Anterior Cingulate Area]])
 +
AM=[[BrainCenterFAM_FT_AM|Amygdala,FAM.FT.AM]]
 +
HC=Hippocampus,FMM.FT.HC (see [[BrainCenterFMM_FT_HF|Hippocampal Formation]])
 +
HT.L=Lateral Hypothalamic Area,LAC.FD.HT.LT (see [[BrainCenterFD_HT|Hypothalamus]])
 +
HT.PV=[[BrainRegionLAC_FD_HT_PV|Paraventricular Nucleus,LAC.FD.HT.PV]]
 +
INS=[[BrainCenterNC_INS|Insular Cortex,NC.INS]]
 +
LC=[[BrainRegionLMC_HT_LC|Locus Coeruleus,LMC.HT.LC]]
 +
MPFC=Orbitofrontal Cortex,NC.AL.OPFC (see [[BrainCenterNC_AL_OMPFC|Orbitomedial Prefrontal Cortex]])
 +
PAG=[[BrainRegionLMC_MM_PAG|Periaqueductal Gray Matter,LMC.MM.PAG]]
 +
PB=[[BrainRegionLPC_HT_PRF_PB|Parabrachial Nucleus,LPC.HT.PRF.PB]]
 +
PUT=[[BrainRegionTARGET_TEA_ENDOCRINE|Endocrine Glands,TARGET.TEA.ENDOCRINE]]
 +
SOL=[[BrainRegionLPC_HL_SOL|Solitary Nucleus,LPC.HL.SOL]]
 +
TH=Thalamus,FD.TH
 +
<img src="http://ahuman.org/svn/ahwiki/images/ext/e212b5f27aa77f69673ce0cb4ce84428.jpg" alt=alt="unavailable" style="max-width: 100%;">
  
  
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(generated)
 
(generated)
  
 +
* http://journal.frontiersin.org/article/10.3389/fnint.2012.00094/full
 
* http://www.intechopen.com/books/computational-intelligence-in-electromyography-analysis-a-perspective-on-current-applications-and-future-challenges/sphincter-emg-for-diagnosing-multiple-system-atrophy-and-related-disorders
 
* http://www.intechopen.com/books/computational-intelligence-in-electromyography-analysis-a-perspective-on-current-applications-and-future-challenges/sphincter-emg-for-diagnosing-multiple-system-atrophy-and-related-disorders
 
* http://www.nature.com/nrn/journal/v11/n6/fig_tab/nrn2849_F7.html
 
* http://www.nature.com/nrn/journal/v11/n6/fig_tab/nrn2849_F7.html
 
* http://www.nature.com/neuro/journal/v5/n10/fig_tab/nn913_F1.html
 
* http://www.nature.com/neuro/journal/v5/n10/fig_tab/nn913_F1.html
 
* http://neuropolitics.org/defaultmay10.asp
 
* http://neuropolitics.org/defaultmay10.asp

Latest revision as of 18:29, 28 April 2019

Locus Coeruleus

@@Home -> BiologicalLifeResearch -> BrainAreaLMC -> BrainRegionLMC_HT_LC

This page covers biological details of component Locus Coeruleus. Region is part of aHuman target integrated biological model.

  • Top-down path to region: Hindbrain Metencephalon -> Locus Coeruleus (LMC.HT.LC) (see Mind Maps)
  • Type: nucleus
  • Quality: L0
  • Brain area: Lower Brain - Modulatory Contol Area (LMC)
  • Area circuit: Norepinephrine - Vigilant Concentration, Stress Hormone, Fight-or-Flight Response (NE)
  • Role: processor.autonomic
  • Function: Regulate the intensity of responses to salient stimuli, arousal and autonomic activity
  • Notes to function:
    • NE Source, enhance signal-to-noise ratio, suppressing irrelevant stimuli (lateral inhibition)
    • inhibitory nucleus
    • wakefulness-promoting nucleus, enhancement of alertness, increase in sympathetic activity and a decrease in parasympathetic activity, to all neocortex, medial septal area, medial preoptic area and substantia innominata, central and basal amygdala, dorsal thalamus

(generated)

Components

(generated)


  • no child items defined

Connectivity

(generated)


LMC.HT.LC.dot.png

Inbound Region Connections:

Source Area Source Region Source Name Type Role Reference
FAM FAM.FT.AM.CEM Medial Central Amygdaloid Nucleus excitatory-glu uncertain Amygdalar disruption of prefrontal cortex (AM -> LC, abstract)
FAM.FT.BNST Bed Nucleus of Stria Terminalis excitatory-glu uncertain (unknown reference)
LAC LAC.FD.HT.DM Dorsomedial Hypothalamic Nucleus excitatory-glu uncertain Effect of light on pupil diameter (DMH -> LC)
LAC.FD.HT.TBM Tuberomammillary Nucleus excitatory-glu uncertain (unknown reference)
LRC LRC.HL.RF.MED Central Medullary Reticular Nucleus excitatory-glu uncertain (unknown reference)
NDM NDM.NC.AL.VACG Ventral Anterior Cingulate Area excitatory-glu uncertain (unknown reference)

Outbound Region Connections:

Target Area Target Region Target Name Type Role Reference
FAM FAM.FD.LHB.LT Lateral Habenula Lateral Part modulatory-ne uncertain Contribution of nAChR subunits to nicotine withdrawal symptoms (LC -> LHB, abstract)
FAM.FD.LHB.MED Lateral Habenula Medial Part modulatory-ne uncertain Contribution of nAChR subunits to nicotine withdrawal symptoms (LC -> LHB, abstract)
FAM.FD.MHB Medial Habenula modulatory-ne uncertain Contribution of nAChR subunits to nicotine withdrawal symptoms (LC -> MHB)
FAM.FT.SEP.DBB Diagonal Band of Broca modulatory-ne uncertain (unknown reference)
FEC FEC.FT.SNC.MED Substantia Nigra Pars Compacta Medial modulatory-ne uncertain (unknown reference)
FEC.HT.TG.IPD Interpeduncular Nucleus modulatory-ne uncertain Contribution of nAChR subunits to nicotine withdrawal symptoms (LC -> IPN)
LAC LAC.FD.HT.VLPO Ventrolateral Preoptic Nucleus modulatory-ne uncertain Simplified NREM sleep-promoting pathway (LC -> VLPO)
LAC.SC.IZ.CSC Ciliospinal Center modulatory-ne uncertain Effect of light on pupil diameter (LC -> IML)
LAC.SC.IZ.IML Intermediolateral Nucleus modulatory-ne uncertain Physiology and pathophysiology of lower urinary tract (LC -> IML)

Thirdparty Circuits

(generated) 

DMH=Dorsomedial Hypothalamic Nucleus,LAC.FD.HT.DM
EW=Edinger-Westphal Nucleus,LAC.MM.EWN
EYE=Eye,TARGET.TSA.EYE
GC=Ciliary Ganglion,LAC.PN.PSYM.CLG
IML=Ciliospinal Center,LAC.SC.IZ.CSC
LC=Locus Coeruleus,LMC.HT.LC
OPN=Pretectal Olivary Nucleus,LRC.MM.PT.PON
PVN=Paraventricular Nucleus,LAC.FD.HT.PV
RET=Retinal Nucleus,LPC.FD.RT
SCG=Superior Cervical Ganglion,LAC.PN.SYM.SCG
SCN=Suprachiasmatic Nucleus,LAC.FD.HT.SCN


CN=Caudate Nucleus,FEC.FT.CN (see Basal Ganglia)
DVM=Vagus Nucleus,LAC.HL.VGN
IMG=Inferior Mesenteric Ganglion,LAC.PN.SYM.IMG
IML=Intermediolateral Nucleus,LAC.SC.IZ.IML
LC=Locus Coeruleus,LMC.HT.LC
MPFC=Orbitofrontal Cortex,NC.AL.OPFC (see Orbitomedial Prefrontal Cortex)
MPOA=Median Preoptic Nucleus,LAC.FD.HT.MPO
NBM=Basal Nucleus of Meynert,LMC.FT.NBM
ONF=Onuf's Nucleus,LPC.SC.VH.ONF
PBN=Parabrachial Nucleus,LPC.HT.PRF.PB
PEL=Pelvic Peripheral Ganglion,LAC.PN.PSYM.PPG
PU=Dorsal Putamen Lateral,FEC.FT.PU.LT
PVN=Paraventricular Nucleus,LAC.FD.HT.PV
SNC=Substantia Nigra Pars Compacta Lateral,FEC.FT.SNC.LT
SPS=Sacral Parasympathetic Nucleus,LAC.SC.IZ.SPS
VTA=Ventral Tegmental Area,LMC.MM.VTA
ZI=Subthalamic Nucleus Caudal,BGA.FD.STN.ZI


IPN=Interpeduncular Nucleus,FEC.HT.TG.IPD
LC=Locus Coeruleus,LMC.HT.LC
LHB=Lateral Habenula,FAM.FD.LHB (see Habenula)
MHB=Medial Habenula,FAM.FD.MHB


LC=Locus Coeruleus,LMC.HT.LC
LDTg=Laterodorsal Tegmental Nucleus,LMC.HT.TG.LDT
TMN=Tuberomammillary Nucleus,LAC.FD.HT.TBM
VLPO=Ventrolateral Preoptic Nucleus,LAC.FD.HT.VLPO


ACG=Anterior Cingulate Cortex,NC.AL.ACG (see Anterior Cingulate Area)
AM=Amygdala,FAM.FT.AM
HC=Hippocampus,FMM.FT.HC (see Hippocampal Formation)
HT.L=Lateral Hypothalamic Area,LAC.FD.HT.LT (see Hypothalamus)
HT.PV=Paraventricular Nucleus,LAC.FD.HT.PV
INS=Insular Cortex,NC.INS
LC=Locus Coeruleus,LMC.HT.LC
MPFC=Orbitofrontal Cortex,NC.AL.OPFC (see Orbitomedial Prefrontal Cortex)
PAG=Periaqueductal Gray Matter,LMC.MM.PAG
PB=Parabrachial Nucleus,LPC.HT.PRF.PB
PUT=Endocrine Glands,TARGET.TEA.ENDOCRINE
SOL=Solitary Nucleus,LPC.HL.SOL
TH=Thalamus,FD.TH


References

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