BrainRegionFEC HT TG IPD
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Interpeduncular Nucleus
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This page covers biological details of component Interpeduncular Nucleus. Region is part of aHuman target integrated biological model.
- Top-down path to region: Hindbrain Metencephalon -> Pontine Tegmental Nuclei (HT.TG) -> Interpeduncular Nucleus (FEC.HT.TG.IPD) (see Mind Maps)
- Type: nucleus
- Quality: L0
- Brain area: Forebrain - Execution Control Area (FEC)
- Area circuit: Motor Flexor Loop (FECMF)
- Role: basal.ganglia.pptn
- Function: postural control, voluntary arm and eye movements
- Notes to function:
- unpaired
(generated)
Components
(generated)
- no child items defined
Connectivity
(generated)
Inbound Region Connections:
Source Area | Source Region | Source Name | Type | Role | Reference |
FAM | FAM.FD.MHB | Medial Habenula | excitatory-glu | uncertain | Connectivity map of the habenula (M -> IPN) |
FEC | FEC.FD.STN.ICD | Subthalamic Nucleus Internal Caudal | excitatory-glu | uncertain | (unknown reference) |
FEC.FT.SNR.MED | Substantia Nigra Pars Reticulata Medial | inhibitory-gaba | uncertain | (unknown reference) | |
FEC.HT.TG.RMTG | Rostromedial Tegmental Nucleus | inhibitory-gaba | uncertain | (unknown reference) | |
LMC | LMC.HT.LC | Locus Coeruleus | modulatory-ne | uncertain | Contribution of nAChR subunits to nicotine withdrawal symptoms (LC -> IPN) |
LMC.HT.TG.LDT | Laterodorsal Tegmental Nucleus | modulatory-ach | uncertain | (unknown reference) |
Outbound Region Connections:
Target Area | Target Region | Target Name | Type | Role | Reference |
FEC | FEC.FD.STN.LT | Subthalamic Nucleus Lateral | modulatory-ach | uncertain | (unknown reference) |
FEC.FT.SNC.LT | Substantia Nigra Pars Compacta Lateral | modulatory-ach | uncertain | Both LHb and MHb control the dopaminergic and serotonergic systems (IPN -> SNc, abstract) | |
FMM | FMM.FT.HC.CA3P | Proximal CA3 of Hippocampus | modulatory-ach | uncertain | Connectivity map of the habenula (IPN -> Hippo, abstract) |
LMC | LMC.HL.RP.MG | Raphe Magnus Nucleus | modulatory-ach | uncertain | Connectivity map of the habenula (IPN -> Raphe, abstract) |
LMC.HT.TG.LDT | Laterodorsal Tegmental Nucleus | modulatory-ach | uncertain | Head Direction Cell Circuit (IPD -> DTN) | |
LMC.MM.PAG | Periaqueductal Gray Matter | modulatory-ach | uncertain | Connectivity map of the habenula (IPN -> PAG) | |
LMC.MM.RP.DRN | Dorsal Raphe Nucleus | modulatory-ach | uncertain | Both LHb and MHb control the dopaminergic and serotonergic systems (IPN -> DRN) | |
LMC.MM.VTA | Ventral Tegmental Area | modulatory-ach | uncertain | Both LHb and MHb control the dopaminergic and serotonergic systems (IPN -> VTA) | |
LRC | LRC.MM.SC.INT | Intermediate Superior Colliculus | modulatory-ach | uncertain | (unknown reference) |
NSA | NSA.FD.LGN | Lateral Geniculate Nucleus | modulatory-ach | uncertain | (unknown reference) |
Thirdparty Circuits
(generated)
- Head Direction Cell Circuit - see Reference (CT.HEAD-DIRECTION)
AD=Anterodorsal Nucleus,FMM.FD.TH.AD DTN=Laterodorsal Tegmental Nucleus,LMC.HT.TG.DTG EC=Entorhinal Cortex,FMM.NC.PH.ET (see Rhinal Cortex) HC=Hippocampus,FMM.FT.HC (see Hippocampal Formation) IPD=Interpeduncular Nucleus,FEC.HT.TG.IPD LD=Lateral Dorsal Nucleus of Thalamus,FMM.FD.TH.LD LHAB=Habenula,FAM.FD.HB LMB=Lateral Mammillary Nucleus,FMM.FD.MB.LMB MVSN=Medial Vestibular Nucleus,LPC.HT.MVBN NPRP=Prepositus Nucleus,LRC.HL.NPH PC=Parietal Lobe,NC.LOBE.PAR PRHC=Postrhinal Cortex,FMM.NC.PH.POR PSUB=Postsubiculum,FMM.NC.PH.POS RSP=Retrosplenial Cortex,NCP.NC.MPL.RSC SUPGEN=Suprageniculate Nucleus of Thalamus,NSA.FD.TH.SG VC=Occipital Lobe,NC.LOBE.OCC
- Both LHb and MHb control the dopaminergic and serotonergic systems - see Reference (CF.HB-DA5HT)
DBB=Diagonal Band of Broca,FAM.FT.SEP.DBB DRN=Dorsal Raphe Nucleus,LMC.MM.RP.DRN GPb=Dorsal Pallidum,FEC.FT.DP (see Basal Ganglia) IPN=Interpeduncular Nucleus,FEC.HT.TG.IPD LHA=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN LHbL=Lateral Habenula Lateral Part,FAM.FD.LHB.LT LHbM=Lateral Habenula Medial Part,FAM.FD.LHB.MED LPO=Ventrolateral Preoptic Nucleus,LAC.FD.HT.VLPO LS=Lateral Septal Nucleus,FAM.FT.SEP.LT MHb=Medial Habenula,FAM.FD.MHB MRN=Raphe Nuclei of Medulla,LMC.HL.RP (see Medullary Reticular Formation) MS=Medial Septal Nucleus,FAM.FT.SEP.MED PS=Posterior Septal Group,FAM.FT.SEP.PG (see Septal Nuclei) RMTg=Rostromedial Tegmental Nucleus,FEC.HT.TG.RMTG SNc=Substantia Nigra Pars Compacta,FEC.FT.SNC (see Basal Ganglia) VP=Ventral Pallidum,FEC.FT.VP (see Basal Ganglia) VTA=Ventral Tegmental Area,LMC.MM.VTA
- Connectivity map of the habenula - see Reference (CF.HB-CONN)
CPu=Striatum,FEC.FT.ST (see Basal Ganglia) EP=Endopiriform Nucleus,FAM.FT.EPF Hippo=Hippocampus,FMM.FT.HC (see Hippocampal Formation) IPN=Interpeduncular Nucleus,FEC.HT.TG.IPD L=Lateral Habenula,FAM.FD.LHB (see Habenula) LH=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN M=Medial Habenula,FAM.FD.MHB NAc=Accumbens Nucleus,FEC.FT.ACC (see Basal Ganglia) PAG=Periaqueductal Gray Matter,LMC.MM.PAG Raphe=Raphe Nuclei of Medulla,LMC.HL.RP (see Medullary Reticular Formation) SNc=Substantia Nigra Pars Compacta,FEC.FT.SNC (see Basal Ganglia) Septum=Septal Nuclei,FAM.FT.SEP VTA=Ventral Tegmental Area,LMC.MM.VTA
- Contribution of nAChR subunits to nicotine withdrawal symptoms - see Reference (CF.HB-NICOTINE)
IPN=Interpeduncular Nucleus,FEC.HT.TG.IPD LC=Locus Coeruleus,LMC.HT.LC LHB=Lateral Habenula,FAM.FD.LHB (see Habenula) MHB=Medial Habenula,FAM.FD.MHB
- Habenula Connections - see Reference (CF.HB-CONNECTIONS)
CPu=Striatum,FEC.FT.ST (see Basal Ganglia) DBB=Diagonal Band of Broca,FAM.FT.SEP.DBB DR=Dorsal Raphe Nucleus,LMC.MM.RP.DRN GPi=Globus Pallidus Internal,FEC.FT.GPI (see Basal Ganglia) IP=Interpeduncular Nucleus,FEC.HT.TG.IPD LH=Lateral Hypothalamic Area,LAC.FD.HT.LT (see Hypothalamus) LHb=Lateral Habenula,FAM.FD.LHB (see Habenula) LPO=Ventrolateral Preoptic Nucleus,LAC.FD.HT.VLPO MHb=Medial Habenula,FAM.FD.MHB MR=Superior Central Raphe Nucleus,LMC.MM.RP.SUC PB=Endocrine Glands,TARGET.TEA.ENDOCRINE S=Septal Nuclei,FAM.FT.SEP SNc=Substantia Nigra Pars Compacta Lateral,FEC.FT.SNC.LT VTA=Ventral Tegmental Area,LMC.MM.VTA
- Connectivity of dorsal diencephalic conduction system - see Reference (CF.HB-ASYMM)
IPN=Interpeduncular Nucleus,FEC.HT.TG.IPD LHb=Lateral Habenula,FAM.FD.LHB (see Habenula) MHb=Medial Habenula,FAM.FD.MHB
References
(generated)
- http://www.scholarpedia.org/article/Head_direction_cells
- http://www.nature.com/neuro/journal/v17/n9/fig_tab/nn.3779_F2.html
- http://jn.physiology.org/content/107/10/2633
- http://www.nature.com/nrn/journal/v11/n6/fig_tab/nrn2849_F7.html
- http://www.scholarpedia.org/article/Habenula
- http://rstb.royalsocietypublishing.org/content/364/1519/1005