BrainRegionFEC FT ACC CORE

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Nucleus Accumbens Core

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This page covers biological details of component Nucleus Accumbens Core. Region is part of aHuman target integrated biological model.

  • Top-down path to region: Forebrain Telencephalon -> Basal Ganglia (FEC.FT.BG) -> Striatum (FEC.FT.ST) -> Ventral Striatum (FEC.FT.VST) -> Accumbens Nucleus (FEC.FT.ACC) -> Nucleus Accumbens Core (FEC.FT.ACC.CORE) (see Mind Maps)
  • Type: nucleus
  • Brain area: Forebrain - Execution Control Area
  • Role: basal.ganglia.striatum
  • Function: cognitive processing of motor function related to reward and reinforcement; encodes new motor programs which facilitate acquisition of given reward in future

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Components

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  • no child items defined

Connectivity

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FEC.FT.ACC.CORE.dot.png

Inbound Region Connections:

Source Area Source Region Source Name Type Reference
FAM FAM.FD.TH.PT Paratenial Nucleus of Thalamus excitatory-glu (unknown reference)
FAM.FT.AM.BP Parvicellular Basal Amygdaloid Nucleus excitatory-glu Amygdala and its network (BLN -> NACC, abstract)
FMM FMM.FD.TH.RH Rhomboidal Nucleus of Thalamus excitatory-glu (unknown reference)
FMM.FT.HC.CA1D Distal CA1 of Hippocampus excitatory-glu Nucleus Accumbens (CA1 -> NACC, abstract)
FMM.FT.HF.SUBD Distal Subiculum excitatory-glu Nucleus Accumbens (SUB -> NACC, abstract)
FMM.FT.HF.SUBP Proximal Subiculum excitatory-glu Nucleus Accumbens (SUB -> NACC, abstract)
FMM.NC.PH.LEC Lateral Entorhinal Cortex excitatory-glu Nucleus Accumbens (EC -> NACC, abstract)
FMM.NC.PH.PAS Parasubiculum excitatory-glu Nucleus Accumbens (PAS -> NACC, abstract)
FMM.NC.PH.PER Perirhinal Cortex excitatory-glu Nucleus Accumbens (PRR -> NACC, abstract)
NDM NDM.FD.TH.PV Paraventricular Nucleus of Thalamus excitatory-glu (unknown reference)
NDM.NC.AL.FPC Lateral Frontopolar Cortex excitatory-glu Affective basal ganglia circuit (OMPFC -> NACC, abstract)

Outbound Region Connections:

Target Area Target Region Target Name Type Reference
FAM FAM.FD.LHB.LT Lateral Habenula Lateral Part inhibitory-gaba Connectivity map of the habenula (NAc -> L, abstract)
FEC FEC.FT.SNC.MED Substantia Nigra Pars Compacta Medial inhibitory-gaba (unknown reference)
FEC.FT.SNR.MED Substantia Nigra Pars Reticulata Medial inhibitory-gaba Craving (NACC -> SNr, abstract)
FEC.FT.VP.DL Ventral Pallidum Dorsolateral inhibitory-gaba Craving (NACC -> VPAL, abstract)
LMC LMC.MM.VTA Ventral Tegmental Area inhibitory-gaba Reward circuit of human brain (NACC -> VTA, abstract)

Thirdparty Circuits

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map: 
BG=Basal Ganglia,FEC.FT.BG
CN=Caudate Nucleus,FEC.FT.CN (see Basal Ganglia)
CR=Cerebellum,LLC.HT.CR (see Cerebellar Complex)
FrontalCortex=Anterior Lobe,NC.LOBE.ANT
GPe=Globus Pallidus External,FEC.FT.GPE (see Basal Ganglia)
LGN=Lateral Geniculate Nucleus,NSA.FD.LGN
LIP=Lateral Intraparietal Sulcus,NPE.NC.IPS.LIP
RF=Pontine Reticular Formation,HT.RF
Retina=Retinal Nucleus,LPC.FD.RT
SCi=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon)
SCs=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon)
SNpr=Substantia Nigra Pars Reticulata Dorsolateral,FEC.FT.SNR.DL
STN=Subthalamic Nucleus,FEC.FD.STN (see Subthalamus Area)
Thalamus=Thalamus,FD.TH
VisualCortex=Occipital Lobe,NC.LOBE.OCC


map: 
AMY=Amygdala,FAM.FT.AM
ARC=Arcuate Nucleus of Hypothalamus,LAC.FD.HT.AR
DS=Dorsal Striatum,FEC.FT.DST (see Basal Ganglia)
LHA=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN
ME=Endocrine Glands,TARGET.TEA.ENDOCRINE
NAc=Accumbens Nucleus,FEC.FT.ACC (see Basal Ganglia)
NTS=Solitary Nucleus,LPC.HL.SOL
OFC=Orbitofrontal Cortex,NC.AL.OPFC (see Orbitomedial Prefrontal Cortex)
PBN=Parabrachial Nucleus,LPC.HT.PRF.PB
PVN=Paraventricular Nucleus,LAC.FD.HT.PV
VMN=Ventromedial Hypothalamic Nucleus,LAC.FD.HT.VM
VTA=Ventral Tegmental Area,LMC.MM.VTA


map: 
AM=Amygdala,FAM.FT.AM
HC=Hippocampus,FMM.FT.HC (see Hippocampal Formation)
NACC=Accumbens Nucleus,FEC.FT.ACC (see Basal Ganglia)
PFC=Orbitofrontal Cortex,NC.AL.OPFC (see Orbitomedial Prefrontal Cortex)
VPAL=Ventral Pallidum,FEC.FT.VP (see Basal Ganglia)
VTA=Ventral Tegmental Area,LMC.MM.VTA


map: 
CPu=Striatum,FEC.FT.ST (see Basal Ganglia)
EP=Endopiriform Nucleus,FAM.FT.EPF
Hippo=Hippocampus,FMM.FT.HC (see Hippocampal Formation)
IPN=Interpeduncular Nucleus,FEC.HT.TG.IPD
L=Lateral Habenula,FAM.FD.LHB (see Habenula)
LH=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN
M=Medial Habenula,FAM.FD.MHB
NAc=Accumbens Nucleus,FEC.FT.ACC (see Basal Ganglia)
PAG=Periaqueductal Gray Matter,LMC.MM.PAG
Raphe=Raphe Nuclei of Medulla,LMC.HL.RP (see Medullary Reticular Formation)
SNc=Substantia Nigra Pars Compacta,FEC.FT.SNC (see Basal Ganglia)
Septum=Septal Nuclei,FAM.FT.SEP
VTA=Ventral Tegmental Area,LMC.MM.VTA


map: 
NACC=Accumbens Nucleus,FEC.FT.ACC (see Basal Ganglia)
OMPFC=Orbitofrontal Cortex,NC.AL.OPFC (see Orbitomedial Prefrontal Cortex)
SNr=Substantia Nigra Pars Reticulata Medial,FEC.FT.SNR.MED
VPAL=Ventral Pallidum,FEC.FT.VP (see Basal Ganglia)
VTA=Ventral Tegmental Area,LMC.MM.VTA


References

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