Difference between revisions of "BrainRegionLAC FD HT LTN"
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− | + | <pre style="color: green">Lateral Hypothalamic Nucleus</pre> | |
− | <pre style="color: green">Lateral Hypothalamic Nucleus | + | |
− | </pre> | + | |
@@[[Home]] -> [[BiologicalLifeResearch]] -> [[BrainAreaLAC]] -> [[BrainRegionLAC_FD_HT_LTN]] | @@[[Home]] -> [[BiologicalLifeResearch]] -> [[BrainAreaLAC]] -> [[BrainRegionLAC_FD_HT_LTN]] | ||
---- | ---- | ||
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Region is part of aHuman target integrated biological model. | Region is part of aHuman target integrated biological model. | ||
− | * | + | * '''Top-down path to region''': Forebrain Diencephalon -> [[BrainCenterFD_HT|Hypothalamus]] (FD.HT) -> Lateral Hypothalamic Area (LAC.FD.HT.LT) -> [[BrainRegionLAC_FD_HT_LTN|Lateral Hypothalamic Nucleus]] (LAC.FD.HT.LTN) (see [[OverallMindMaps|Mind Maps]]) |
− | * | + | * '''Type''': nucleus |
− | * *Brain area | + | * '''Quality''': L0 |
− | * *Role | + | * '''Brain area''': [[BrainAreaLAC|Lower Brain - Autonomous Control Area]] (LAC) |
− | * | + | * '''Area circuit''': Thirst and Hunger Control (LATH) |
− | * | + | * '''Role''': processor.autonomic |
+ | * '''Function''': feeding center | ||
+ | * '''Notes to function''': | ||
+ | ** lesions - lack of appetite | ||
(generated) | (generated) | ||
= Components = | = Components = | ||
Line 25: | Line 26: | ||
− | http://ahuman. | + | http://ahuman.org/svn/ahwiki/images/dot/LAC.FD.HT.LTN.dot.png |
− | + | '''Inbound Region Connections:''' | |
− | || | + | {| class=wikitable width=80% |
− | || [[BrainAreaFAM|FAM]] || [[BrainRegionFAM_FT_AM_CEM FAM.FT.AM.CEM]] || Medial Central Amygdaloid Nucleus || excitatory-glu || | + | | '''Source Area''' || '''Source Region''' || '''Source Name''' || '''Type''' || '''Role''' || '''Reference''' |
− | + | |- | |
− | + | | [[BrainAreaFAM|FAM]] || [[BrainRegionFAM_FT_AM_BP|FAM.FT.AM.BP]] || Parvicellular Basal Amygdaloid Nucleus || excitatory-glu || uncertain ||[http://www.surgicalneurologyint.com/article.asp?issn=2152-7806;year=2012;volume=3;issue=2;spage=40;epage=46;aulast=Langevin Amygdala and its network (BLN -> HTS)] | |
− | || [[BrainAreaLAC|LAC]] || [[BrainRegionLAC_FD_HT_AR LAC.FD.HT.AR]] || Arcuate Nucleus of Hypothalamus || excitatory-glu || | + | |- |
− | || || [[BrainRegionLAC_FD_HT_DM|LAC.FD.HT.DM]] || Dorsomedial Hypothalamic Nucleus || excitatory-glu || ( | + | | || [[BrainRegionFAM_FT_AM_CEM|FAM.FT.AM.CEM]] || Medial Central Amygdaloid Nucleus || excitatory-glu || uncertain ||[http://neuropolitics.org/defaultmay10.asp Amygdalar disruption of prefrontal cortex (AM -> HT.L, abstract)] |
+ | |- | ||
+ | | || [[BrainRegionFAM_FT_SEP_SH|FAM.FT.SEP.SH]] || Septohippocampal Nucleus || excitatory-glu || uncertain ||[http://www.thebrainlabs.com Cingulate Gyrus (SEP -> HT, abstract)] | ||
+ | |- | ||
+ | | [[BrainAreaFEC|FEC]] || [[BrainRegionFEC_FT_ACC_SH|FEC.FT.ACC.SH]] || Nucleus Accumbens Shell || inhibitory-gaba || uncertain ||(unknown reference) | ||
+ | |- | ||
+ | | [[BrainAreaLAC|LAC]] || [[BrainRegionLAC_FD_HT_AR|LAC.FD.HT.AR]] || Arcuate Nucleus of Hypothalamus || excitatory-glu || uncertain ||[http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.122.2314rep=rep1type=pdf Intrahypothalamic connections important for neural control of food intake and energy balance (ARC -> LHA)] | ||
+ | |- | ||
+ | | || [[BrainRegionLAC_FD_HT_DM|LAC.FD.HT.DM]] || Dorsomedial Hypothalamic Nucleus || excitatory-glu || uncertain ||[http://www.dana.org/Publications/ReportDetails.aspx?id=44217 Eating and sleeping to survive (DMH -> LHA)] | ||
+ | |- | ||
+ | | || [[BrainRegionLAC_FD_HT_VM|LAC.FD.HT.VM]] || Ventromedial Hypothalamic Nucleus || excitatory-glu || uncertain ||[http://ajpregu.physiology.org/content/302/2/R215 Glucose-sensing neural network (VMH -> LHA)] | ||
+ | |- | ||
+ | | [[BrainAreaLPC|LPC]] || [[BrainRegionLPC_HL_SOL|LPC.HL.SOL]] || Solitary Nucleus || excitatory-glu || uncertain ||[http://neuroscience.uth.tmc.edu/s4/chapter04.html Schematic of hypothalamic circuitry underlying satiety (NTS -> LHA)] | ||
+ | |} | ||
− | + | '''Outbound Region Connections:''' | |
− | || | + | {| class=wikitable width=80% |
− | || [[BrainAreaFAM|FAM]] || [[BrainRegionFAM_FD_LHB_LT FAM.FD.LHB.LT]] || Lateral Habenula Lateral Part || excitatory-glu || | + | | '''Target Area''' || '''Target Region''' || '''Target Name''' || '''Type''' || '''Role''' || '''Reference''' |
− | | | + | |- |
− | || | + | | [[BrainAreaFAM|FAM]] || [[BrainRegionFAM_FD_LHB_LT|FAM.FD.LHB.LT]] || Lateral Habenula Lateral Part || excitatory-glu || uncertain || [http://journal.frontiersin.org/article/10.3389/fnhum.2013.00826/full Regulation of the rapid eye movement (REM) sleep by habenular projection (LHT -> LHbL)] |
− | + | |- | |
+ | | || [[BrainRegionFAM_FD_LHB_MED|FAM.FD.LHB.MED]] || Lateral Habenula Medial Part || excitatory-glu || uncertain || [http://www.nature.com/neuro/journal/v17/n9/fig_tab/nn.3779_F2.html Both LHb and MHb control the dopaminergic and serotonergic systems (LHA -> LHbM)] | ||
+ | |- | ||
+ | | [[BrainAreaLAC|LAC]] || [[BrainRegionLAC_FD_HT_PV|LAC.FD.HT.PV]] || Paraventricular Nucleus || excitatory-glu || uncertain || [http://neuroscience.uth.tmc.edu/s4/chapter04.html Schematic of hypothalamic circuitry underlying satiety (LHA -> PVN)] | ||
+ | |- | ||
+ | | [[BrainAreaLMC|LMC]] || [[BrainRegionLMC_HL_RP_MG|LMC.HL.RP.MG]] || Raphe Magnus Nucleus || excitatory-glu || uncertain || (unknown reference) | ||
+ | |- | ||
+ | | [[BrainAreaNDM|NDM]] || [[BrainRegionNDM_NC_AL_ROFCS|NDM.NC.AL.ROFCS]] || Sulcal Rostral Orbitofrontal Cortex || excitatory-glu || uncertain || [http://www.nature.com/nrendo/journal/v6/n8/fig_tab/nrendo.2010.93_F1.html Bowels control brain: gut hormones and obesity (LHA -> OFC, abstract)] | ||
+ | |} | ||
= Thirdparty Circuits = | = Thirdparty Circuits = | ||
(generated) | (generated) | ||
− | * | + | * [http://neuroscience.uth.tmc.edu/s4/images/dougherty/pdougherty4_3.jpg Schematic of hypothalamic circuitry underlying satiety] - see [http://neuroscience.uth.tmc.edu/s4/chapter04.html Reference] (CP.SATIETY) |
+ | |||
+ | ARC=[[BrainRegionLAC_FD_HT_AR|Arcuate Nucleus of Hypothalamus,LAC.FD.HT.AR]] | ||
+ | DMH=[[BrainRegionLAC_FD_HT_DM|Dorsomedial Hypothalamic Nucleus,LAC.FD.HT.DM]] | ||
+ | LHA=[[BrainRegionLAC_FD_HT_LTN|Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN]] | ||
+ | NTS=[[BrainRegionLPC_HL_SOL|Solitary Nucleus,LPC.HL.SOL]] | ||
+ | PVN=[[BrainRegionLAC_FD_HT_PV|Paraventricular Nucleus,LAC.FD.HT.PV]] | ||
+ | VMH=[[BrainRegionLAC_FD_HT_VM|Ventromedial Hypothalamic Nucleus,LAC.FD.HT.VM]] | ||
+ | <img src="http://ahuman.org/svn/ahwiki/images/ext/6f1f0e26e147b046d3567a72e62038bb.jpg" alt=alt="unavailable" style="max-width: 100%;"> | ||
+ | |||
+ | * [http://www.nature.com/nrendo/journal/v6/n8/images/nrendo.2010.93-f1.jpg Bowels control brain: gut hormones and obesity] - see [http://www.nature.com/nrendo/journal/v6/n8/fig_tab/nrendo.2010.93_F1.html Reference] (CP.BOWELS) | ||
+ | |||
+ | AMY=[[BrainCenterFAM_FT_AM|Amygdala,FAM.FT.AM]] | ||
+ | ARC=[[BrainRegionLAC_FD_HT_AR|Arcuate Nucleus of Hypothalamus,LAC.FD.HT.AR]] | ||
+ | DS=Dorsal Striatum,FEC.FT.DST (see [[BrainCenterFEC_FT_BG|Basal Ganglia]]) | ||
+ | LHA=[[BrainRegionLAC_FD_HT_LTN|Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN]] | ||
+ | ME=[[BrainRegionTARGET_TEA_ENDOCRINE|Endocrine Glands,TARGET.TEA.ENDOCRINE]] | ||
+ | NAc=Accumbens Nucleus,FEC.FT.ACC (see [[BrainCenterFEC_FT_BG|Basal Ganglia]]) | ||
+ | NTS=[[BrainRegionLPC_HL_SOL|Solitary Nucleus,LPC.HL.SOL]] | ||
+ | OFC=Orbitofrontal Cortex,NC.AL.OPFC (see [[BrainCenterNC_AL_OMPFC|Orbitomedial Prefrontal Cortex]]) | ||
+ | PBN=[[BrainRegionLPC_HT_PRF_PB|Parabrachial Nucleus,LPC.HT.PRF.PB]] | ||
+ | PVN=[[BrainRegionLAC_FD_HT_PV|Paraventricular Nucleus,LAC.FD.HT.PV]] | ||
+ | VMN=[[BrainRegionLAC_FD_HT_VM|Ventromedial Hypothalamic Nucleus,LAC.FD.HT.VM]] | ||
+ | VTA=[[BrainRegionLMC_MM_VTA|Ventral Tegmental Area,LMC.MM.VTA]] | ||
+ | <img src="http://ahuman.org/svn/ahwiki/images/ext/1550acf4cfac7352ce9d8ba11a39c4e6.jpg" alt=alt="unavailable" style="max-width: 100%;"> | ||
+ | |||
+ | * [http://www.frontiersin.org/files/Articles/70852/fnhum-07-00826-HTML/image_m/fnhum-07-00826-g002.jpg Regulation of the rapid eye movement (REM) sleep by habenular projection] - see [http://journal.frontiersin.org/article/10.3389/fnhum.2013.00826/full Reference] (CF.REM-HB) | ||
+ | |||
+ | DBB=[[BrainRegionFAM_FT_SEP_DBB|Diagonal Band of Broca,FAM.FT.SEP.DBB]] | ||
+ | DTG=[[BrainRegionLMC_HT_TG_LDT|Laterodorsal Tegmental Nucleus,LMC.HT.TG.DTG]] | ||
+ | EPN=[[BrainRegionFAM_FT_EPF|Endopiriform Nucleus,FAM.FT.EPF]] | ||
+ | GPi=Globus Pallidus Internal,FEC.FT.GPI (see [[BrainCenterFEC_FT_BG|Basal Ganglia]]) | ||
+ | LHT=[[BrainRegionLAC_FD_HT_LTN|Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN]] | ||
+ | LHbL=[[BrainRegionFAM_FD_LHB_LT|Lateral Habenula Lateral Part,FAM.FD.LHB.LT]] | ||
+ | LHbM=[[BrainRegionFAM_FD_LHB_MED|Lateral Habenula Medial Part,FAM.FD.LHB.MED]] | ||
+ | NI=[[BrainRegionFAM_HT_TG_NI|Incertus Nucleus,FAM.HT.TG.NI]] | ||
+ | RMTg=[[BrainRegionFEC_HT_TG_RMTG|Rostromedial Tegmental Nucleus,FEC.HT.TG.RMTG]] | ||
+ | Raphe=Raphe Nuclei of Medulla,LMC.HL.RP (see [[BrainCenterHL_RF|Medullary Reticular Formation]]) | ||
+ | SNc=Substantia Nigra Pars Compacta,FEC.FT.SNC (see [[BrainCenterFEC_FT_BG|Basal Ganglia]]) | ||
+ | VTA=[[BrainRegionLMC_MM_VTA|Ventral Tegmental Area,LMC.MM.VTA]] | ||
+ | VTG=[[BrainRegionLMC_MM_VTA|Ventral Tegmental Area,LMC.MM.VTG]] | ||
+ | <img src="http://ahuman.org/svn/ahwiki/images/ext/9876de47985d221848d9333bddb7bf59.jpg" alt=alt="unavailable" style="max-width: 100%;"> | ||
+ | |||
+ | * [http://www.nature.com/neuro/journal/v17/n9/images/nn.3779-F2.jpg Both LHb and MHb control the dopaminergic and serotonergic systems] - see [http://www.nature.com/neuro/journal/v17/n9/fig_tab/nn.3779_F2.html Reference] (CF.HB-DA5HT) | ||
+ | |||
+ | DBB=[[BrainRegionFAM_FT_SEP_DBB|Diagonal Band of Broca,FAM.FT.SEP.DBB]] | ||
+ | DRN=[[BrainRegionLMC_MM_RP_DRN|Dorsal Raphe Nucleus,LMC.MM.RP.DRN]] | ||
+ | GPb=Dorsal Pallidum,FEC.FT.DP (see [[BrainCenterFEC_FT_BG|Basal Ganglia]]) | ||
+ | IPN=[[BrainRegionFEC_HT_TG_IPD|Interpeduncular Nucleus,FEC.HT.TG.IPD]] | ||
+ | LHA=[[BrainRegionLAC_FD_HT_LTN|Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN]] | ||
+ | LHbL=[[BrainRegionFAM_FD_LHB_LT|Lateral Habenula Lateral Part,FAM.FD.LHB.LT]] | ||
+ | LHbM=[[BrainRegionFAM_FD_LHB_MED|Lateral Habenula Medial Part,FAM.FD.LHB.MED]] | ||
+ | LPO=[[BrainRegionLAC_FD_HT_VLPO|Ventrolateral Preoptic Nucleus,LAC.FD.HT.VLPO]] | ||
+ | LS=[[BrainRegionFAM_FT_SEP_LT|Lateral Septal Nucleus,FAM.FT.SEP.LT]] | ||
+ | MHb=[[BrainRegionFAM_FD_MHB|Medial Habenula,FAM.FD.MHB]] | ||
+ | MRN=Raphe Nuclei of Medulla,LMC.HL.RP (see [[BrainCenterHL_RF|Medullary Reticular Formation]]) | ||
+ | MS=[[BrainRegionFAM_FT_SEP_MED|Medial Septal Nucleus,FAM.FT.SEP.MED]] | ||
+ | PS=Posterior Septal Group,FAM.FT.SEP.PG (see [[BrainCenterFAM_FT_SEP|Septal Nuclei]]) | ||
+ | RMTg=[[BrainRegionFEC_HT_TG_RMTG|Rostromedial Tegmental Nucleus,FEC.HT.TG.RMTG]] | ||
+ | SNc=Substantia Nigra Pars Compacta,FEC.FT.SNC (see [[BrainCenterFEC_FT_BG|Basal Ganglia]]) | ||
+ | VP=Ventral Pallidum,FEC.FT.VP (see [[BrainCenterFEC_FT_BG|Basal Ganglia]]) | ||
+ | VTA=[[BrainRegionLMC_MM_VTA|Ventral Tegmental Area,LMC.MM.VTA]] | ||
+ | <img src="http://ahuman.org/svn/ahwiki/images/ext/97cf0802ee48a418ff7f70f80ce204e1.jpg" alt=alt="unavailable" style="max-width: 100%;"> | ||
+ | |||
+ | * [http://www.nature.com/npp/journal/v35/n1/images/npp2009121f1.jpg Fear regulation] - see [https://brmlab.cz/project/brain_hacking/tdcs/pfc Reference] (CF.FEAR-REG) | ||
+ | |||
+ | B=Basal Amygdaloid Nucleus,FAM.FT.AM.B (see [[BrainCenterFAM_FT_AM|Amygdala]]) | ||
+ | CE=Central Amygdala,FAM.FT.AM.CEA (see [[BrainCenterFAM_FT_AM|Amygdala]]) | ||
+ | Hippocampus=Hippocampus,FMM.FT.HC (see [[BrainCenterFMM_FT_HF|Hippocampal Formation]]) | ||
+ | Hypothalamus=[[BrainCenterFD_HT|Hypothalamus,FD.HT]] | ||
+ | ITC=[[BrainRegionFAM_FT_AM_ITC|Intercalated Amygdaloid Nuclei,FAM.FT.AM.ITC]] | ||
+ | LA=Lateral Amygdaloid Nucleus,FAM.FT.AM.LA (see [[BrainCenterFAM_FT_AM|Amygdala]]) | ||
+ | Striatum=Striatum,FEC.FT.ST (see [[BrainCenterFEC_FT_BG|Basal Ganglia]]) | ||
+ | dlPFC=Mid-Dorsolateral Prefrontal Cortex,NDM.NC.AL.DLPFC (see [[BrainCenterNC_AL_LPFC|Lateral Prefrontal Cortex]]) | ||
+ | vmPFC=[[BrainRegionNDM_NC_AL_VMPFC|Ventromedial Prefrontal Cortex,NDM.NC.AL.VMPFC]] | ||
+ | <img src="http://ahuman.org/svn/ahwiki/images/ext/0109abd5f9ba228b2df07c466da4b771.jpg" alt=alt="unavailable" style="max-width: 100%;"> | ||
+ | |||
+ | * [http://dkqlgfb5sk2dk.cloudfront.net/content/ajpregu/302/2/R215/F1.large.jpg Glucose-sensing neural network] - see [http://ajpregu.physiology.org/content/302/2/R215 Reference] (CP.GLUCOSE) | ||
+ | |||
+ | ARC=[[BrainRegionLAC_FD_HT_AR|Arcuate Nucleus of Hypothalamus,LAC.FD.HT.AR]] | ||
+ | DMN=[[BrainRegionLAC_FD_HT_DM|Dorsomedial Hypothalamic Nucleus,LAC.FD.HT.DM]] | ||
+ | LHA=[[BrainRegionLAC_FD_HT_LTN|Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN]] | ||
+ | PVH=[[BrainRegionLAC_FD_HT_PV|Paraventricular Nucleus,LAC.FD.HT.PV]] | ||
+ | VMH=[[BrainRegionLAC_FD_HT_VM|Ventromedial Hypothalamic Nucleus,LAC.FD.HT.VM]] | ||
+ | <img src="http://ahuman.org/svn/ahwiki/images/ext/0cd27888f0cfd10857510d32768c3815.jpg" alt=alt="unavailable" style="max-width: 100%;"> | ||
+ | |||
+ | * [http://www.pnas.org/content/103/32/12150/F7.large.jpg Food-entrainable circadian oscillator] - see [http://www.pnas.org/content/103/32/12150/F7.expansion.html Reference] (CP.FOOD-OCSILLATOR) | ||
+ | |||
+ | DMH=[[BrainRegionLAC_FD_HT_DM|Dorsomedial Hypothalamic Nucleus,LAC.FD.HT.DM]] | ||
+ | LH=[[BrainRegionLAC_FD_HT_LTN|Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN]] | ||
+ | NTS=[[BrainRegionLPC_HL_SOL|Solitary Nucleus,LPC.HL.SOL]] | ||
+ | PBN=[[BrainRegionLPC_HT_PRF_PB|Parabrachial Nucleus,LPC.HT.PRF.PB]] | ||
+ | PVH=[[BrainRegionLAC_FD_HT_PV|Paraventricular Nucleus,LAC.FD.HT.PV]] | ||
+ | SCN=[[BrainRegionLAC_FD_HT_SCN|Suprachiasmatic Nucleus,LAC.FD.HT.SCN]] | ||
+ | <img src="http://ahuman.org/svn/ahwiki/images/ext/8f1f58bb00bedda8aee035b59f4b1a61.jpg" alt=alt="unavailable" style="max-width: 100%;" height=300> | ||
+ | |||
+ | * [http://www.dana.org/uploadedImages/Images/Content_Images/SenBodyFunc2_PR2007_cont.jpg Eating and sleeping to survive] - see [http://www.dana.org/Publications/ReportDetails.aspx?id=44217 Reference] (CP.DMH-CYCLES) | ||
+ | |||
+ | ARC=[[BrainRegionLAC_FD_HT_AR|Arcuate Nucleus of Hypothalamus,LAC.FD.HT.AR]] | ||
+ | DMH=[[BrainRegionLAC_FD_HT_DM|Dorsomedial Hypothalamic Nucleus,LAC.FD.HT.DM]] | ||
+ | LHA=[[BrainRegionLAC_FD_HT_LTN|Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN]] | ||
+ | MPO=[[BrainRegionLAC_FD_HT_MPO|Median Preoptic Nucleus,LAC.FD.HT.MPO]] | ||
+ | PVH=[[BrainRegionLAC_FD_HT_PV|Paraventricular Nucleus,LAC.FD.HT.PV]] | ||
+ | SCN=[[BrainRegionLAC_FD_HT_SCN|Suprachiasmatic Nucleus,LAC.FD.HT.SCN]] | ||
+ | VLPO=[[BrainRegionLAC_FD_HT_VLPO|Ventrolateral Preoptic Nucleus,LAC.FD.HT.VLPO]] | ||
+ | VMH=[[BrainRegionLAC_FD_HT_VM|Ventromedial Hypothalamic Nucleus,LAC.FD.HT.VM]] | ||
+ | <img src="http://ahuman.org/svn/ahwiki/images/ext/aaf05c2cb0453d5f112754ade7c03956.jpg" alt=alt="unavailable" style="max-width: 100%;"> | ||
+ | |||
+ | * [http://usvn.ahuman.org/svn/ahwiki/images/wiki/research/biomodel/intrahypothalamic.png Intrahypothalamic connections important for neural control of food intake and energy balance] - see [http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.122.2314rep=rep1type=pdf Reference] (CL.INTRAHYPOTHALAMIC) | ||
+ | |||
+ | AH=[[BrainRegionLAC_FD_HT_AH|Anterior Hypothalamic Nucleus,LAC.FD.HT.AH]] | ||
+ | ARC=[[BrainRegionLAC_FD_HT_AR|Arcuate Nucleus of Hypothalamus,LAC.FD.HT.AR]] | ||
+ | DMN=[[BrainRegionLAC_FD_HT_DM|Dorsomedial Hypothalamic Nucleus,LAC.FD.HT.DM]] | ||
+ | LHA=[[BrainRegionLAC_FD_HT_LTN|Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN]] | ||
+ | MPOA=[[BrainRegionLAC_FD_HT_MPO|Median Preoptic Nucleus,LAC.FD.HT.MPO]] | ||
+ | PA=[[BrainRegionLAC_FD_HT_PV|Paraventricular Nucleus,LAC.FD.HT.PV]] | ||
+ | SCH=[[BrainRegionLAC_FD_HT_SCN|Suprachiasmatic Nucleus,LAC.FD.HT.SCN]] | ||
+ | SON=[[BrainRegionLAC_FD_HT_SO|Supraoptic Nucleus,LAC.FD.HT.SO]] | ||
+ | VMN=[[BrainRegionLAC_FD_HT_VM|Ventromedial Hypothalamic Nucleus,LAC.FD.HT.VM]] | ||
+ | <img src="http://ahuman.org/svn/ahwiki/images/ext/812cda92ff47d048aeb22ce670a9a9fb.png" alt=alt="unavailable" style="max-width: 100%;"> | ||
+ | |||
+ | * [http://d2avczb82rh8fa.cloudfront.net/content/jn/107/10/2633/F1.large.jpg Connectivity map of the habenula] - see [http://jn.physiology.org/content/107/10/2633 Reference] (CF.HB-CONN) | ||
+ | |||
+ | CPu=Striatum,FEC.FT.ST (see [[BrainCenterFEC_FT_BG|Basal Ganglia]]) | ||
+ | EP=[[BrainRegionFAM_FT_EPF|Endopiriform Nucleus,FAM.FT.EPF]] | ||
+ | Hippo=Hippocampus,FMM.FT.HC (see [[BrainCenterFMM_FT_HF|Hippocampal Formation]]) | ||
+ | IPN=[[BrainRegionFEC_HT_TG_IPD|Interpeduncular Nucleus,FEC.HT.TG.IPD]] | ||
+ | L=Lateral Habenula,FAM.FD.LHB (see [[BrainCenterFAM_FD_HB|Habenula]]) | ||
+ | LH=[[BrainRegionLAC_FD_HT_LTN|Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN]] | ||
+ | M=[[BrainRegionFAM_FD_MHB|Medial Habenula,FAM.FD.MHB]] | ||
+ | NAc=Accumbens Nucleus,FEC.FT.ACC (see [[BrainCenterFEC_FT_BG|Basal Ganglia]]) | ||
+ | PAG=[[BrainRegionLMC_MM_PAG|Periaqueductal Gray Matter,LMC.MM.PAG]] | ||
+ | Raphe=Raphe Nuclei of Medulla,LMC.HL.RP (see [[BrainCenterHL_RF|Medullary Reticular Formation]]) | ||
+ | SNc=Substantia Nigra Pars Compacta,FEC.FT.SNC (see [[BrainCenterFEC_FT_BG|Basal Ganglia]]) | ||
+ | Septum=[[BrainCenterFAM_FT_SEP|Septal Nuclei,FAM.FT.SEP]] | ||
+ | VTA=[[BrainRegionLMC_MM_VTA|Ventral Tegmental Area,LMC.MM.VTA]] | ||
+ | <img src="http://ahuman.org/svn/ahwiki/images/ext/213e030f063f9640f8ace79244e622d1.jpg" alt=alt="unavailable" style="max-width: 100%;"> | ||
+ | |||
+ | * [http://sni.wpengine.com/wp-content/uploads/2015/05/3520/SNI-3-40-g001.png Amygdala and its network] - see [http://www.surgicalneurologyint.com/article.asp?issn=2152-7806;year=2012;volume=3;issue=2;spage=40;epage=46;aulast=Langevin Reference] (CF.AM-NET) | ||
+ | |||
+ | BLN=[[BrainRegionFAM_FT_AM_BP|Parvicellular Basal Amygdaloid Nucleus,FAM.FT.AM.BP]] | ||
+ | CEA=Central Amygdala,FAM.FT.AM.CEA (see [[BrainCenterFAM_FT_AM|Amygdala]]) | ||
+ | EC=Entorhinal Cortex,FMM.NC.PH.ET (see [[BrainCenterNC_PHA_RH|Rhinal Cortex]]) | ||
+ | HC=Hippocampus,FMM.FT.HC (see [[BrainCenterFMM_FT_HF|Hippocampal Formation]]) | ||
+ | HTS=[[BrainRegionLAC_FD_HT_LTN|Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN]] | ||
+ | ITC=[[BrainRegionNSA_NC_IT_TE|Inferotemporal Cortex,NSA.NC.IT.TE]] | ||
+ | LA=Lateral Amygdaloid Nucleus,FAM.FT.AM.LA (see [[BrainCenterFAM_FT_AM|Amygdala]]) | ||
+ | LHB=Lateral Habenula,FAM.FD.LHB (see [[BrainCenterFAM_FD_HB|Habenula]]) | ||
+ | MD=Mediodorsal Nucleus of Thalamus,FD.TH.MD (see [[BrainCenterFD_TH_CR|Cognitive Thalamus]]) | ||
+ | MPFC=[[BrainCenterNC_AL_OMPFC|Orbitomedial Prefrontal Cortex,NC.AL.OMPFC]] | ||
+ | NACC=Accumbens Nucleus,FEC.FT.ACC (see [[BrainCenterFEC_FT_BG|Basal Ganglia]]) | ||
+ | PAG=[[BrainRegionLMC_MM_PAG|Periaqueductal Gray Matter,LMC.MM.PAG]] | ||
+ | RMTG=[[BrainRegionFEC_HT_TG_RMTG|Rostromedial Tegmental Nucleus,FEC.HT.TG.RMTG]] | ||
+ | STC=[[BrainRegionNSA_NC_STG_A3|Wernicke's area A3,NSA.NC.STG.A3]] | ||
+ | VGDM=[[BrainRegionLAC_HL_VGN|Vagus Nucleus,LAC.HL.VGN]] | ||
+ | VTA=[[BrainRegionLMC_MM_VTA|Ventral Tegmental Area,LMC.MM.VTA]] | ||
+ | <img src="http://ahuman.org/svn/ahwiki/images/ext/148ecc584cca86040df3ac88ecdbcba6.png" alt=alt="unavailable" style="max-width: 100%;"> | ||
+ | |||
= References = | = References = | ||
(generated) | (generated) | ||
− | * | + | * http://neuroscience.uth.tmc.edu/s4/chapter04.html |
+ | * http://www.nature.com/nrendo/journal/v6/n8/fig_tab/nrendo.2010.93_F1.html | ||
+ | * http://journal.frontiersin.org/article/10.3389/fnhum.2013.00826/full | ||
+ | * http://www.nature.com/neuro/journal/v17/n9/fig_tab/nn.3779_F2.html | ||
+ | * https://brmlab.cz/project/brain_hacking/tdcs/pfc | ||
+ | * http://ajpregu.physiology.org/content/302/2/R215 | ||
+ | * http://www.pnas.org/content/103/32/12150/F7.expansion.html | ||
+ | * http://www.dana.org/Publications/ReportDetails.aspx?id=44217 | ||
+ | * http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.122.2314rep=rep1type=pdf | ||
+ | * http://jn.physiology.org/content/107/10/2633 | ||
+ | * http://www.surgicalneurologyint.com/article.asp?issn=2152-7806;year=2012;volume=3;issue=2;spage=40;epage=46;aulast=Langevin |
Latest revision as of 18:27, 28 April 2019
Lateral Hypothalamic Nucleus
@@Home -> BiologicalLifeResearch -> BrainAreaLAC -> BrainRegionLAC_FD_HT_LTN
This page covers biological details of component Lateral Hypothalamic Nucleus. Region is part of aHuman target integrated biological model.
- Top-down path to region: Forebrain Diencephalon -> Hypothalamus (FD.HT) -> Lateral Hypothalamic Area (LAC.FD.HT.LT) -> Lateral Hypothalamic Nucleus (LAC.FD.HT.LTN) (see Mind Maps)
- Type: nucleus
- Quality: L0
- Brain area: Lower Brain - Autonomous Control Area (LAC)
- Area circuit: Thirst and Hunger Control (LATH)
- Role: processor.autonomic
- Function: feeding center
- Notes to function:
- lesions - lack of appetite
(generated)
Components
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- no child items defined
Connectivity
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Inbound Region Connections:
Source Area | Source Region | Source Name | Type | Role | Reference |
FAM | FAM.FT.AM.BP | Parvicellular Basal Amygdaloid Nucleus | excitatory-glu | uncertain | Amygdala and its network (BLN -> HTS) |
FAM.FT.AM.CEM | Medial Central Amygdaloid Nucleus | excitatory-glu | uncertain | Amygdalar disruption of prefrontal cortex (AM -> HT.L, abstract) | |
FAM.FT.SEP.SH | Septohippocampal Nucleus | excitatory-glu | uncertain | Cingulate Gyrus (SEP -> HT, abstract) | |
FEC | FEC.FT.ACC.SH | Nucleus Accumbens Shell | inhibitory-gaba | uncertain | (unknown reference) |
LAC | LAC.FD.HT.AR | Arcuate Nucleus of Hypothalamus | excitatory-glu | uncertain | Intrahypothalamic connections important for neural control of food intake and energy balance (ARC -> LHA) |
LAC.FD.HT.DM | Dorsomedial Hypothalamic Nucleus | excitatory-glu | uncertain | Eating and sleeping to survive (DMH -> LHA) | |
LAC.FD.HT.VM | Ventromedial Hypothalamic Nucleus | excitatory-glu | uncertain | Glucose-sensing neural network (VMH -> LHA) | |
LPC | LPC.HL.SOL | Solitary Nucleus | excitatory-glu | uncertain | Schematic of hypothalamic circuitry underlying satiety (NTS -> LHA) |
Outbound Region Connections:
Target Area | Target Region | Target Name | Type | Role | Reference |
FAM | FAM.FD.LHB.LT | Lateral Habenula Lateral Part | excitatory-glu | uncertain | Regulation of the rapid eye movement (REM) sleep by habenular projection (LHT -> LHbL) |
FAM.FD.LHB.MED | Lateral Habenula Medial Part | excitatory-glu | uncertain | Both LHb and MHb control the dopaminergic and serotonergic systems (LHA -> LHbM) | |
LAC | LAC.FD.HT.PV | Paraventricular Nucleus | excitatory-glu | uncertain | Schematic of hypothalamic circuitry underlying satiety (LHA -> PVN) |
LMC | LMC.HL.RP.MG | Raphe Magnus Nucleus | excitatory-glu | uncertain | (unknown reference) |
NDM | NDM.NC.AL.ROFCS | Sulcal Rostral Orbitofrontal Cortex | excitatory-glu | uncertain | Bowels control brain: gut hormones and obesity (LHA -> OFC, abstract) |
Thirdparty Circuits
(generated)
- Schematic of hypothalamic circuitry underlying satiety - see Reference (CP.SATIETY)
ARC=Arcuate Nucleus of Hypothalamus,LAC.FD.HT.AR DMH=Dorsomedial Hypothalamic Nucleus,LAC.FD.HT.DM LHA=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN NTS=Solitary Nucleus,LPC.HL.SOL PVN=Paraventricular Nucleus,LAC.FD.HT.PV VMH=Ventromedial Hypothalamic Nucleus,LAC.FD.HT.VM
- Bowels control brain: gut hormones and obesity - see Reference (CP.BOWELS)
AMY=Amygdala,FAM.FT.AM ARC=Arcuate Nucleus of Hypothalamus,LAC.FD.HT.AR DS=Dorsal Striatum,FEC.FT.DST (see Basal Ganglia) LHA=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN ME=Endocrine Glands,TARGET.TEA.ENDOCRINE NAc=Accumbens Nucleus,FEC.FT.ACC (see Basal Ganglia) NTS=Solitary Nucleus,LPC.HL.SOL OFC=Orbitofrontal Cortex,NC.AL.OPFC (see Orbitomedial Prefrontal Cortex) PBN=Parabrachial Nucleus,LPC.HT.PRF.PB PVN=Paraventricular Nucleus,LAC.FD.HT.PV VMN=Ventromedial Hypothalamic Nucleus,LAC.FD.HT.VM VTA=Ventral Tegmental Area,LMC.MM.VTA
- Regulation of the rapid eye movement (REM) sleep by habenular projection - see Reference (CF.REM-HB)
DBB=Diagonal Band of Broca,FAM.FT.SEP.DBB DTG=Laterodorsal Tegmental Nucleus,LMC.HT.TG.DTG EPN=Endopiriform Nucleus,FAM.FT.EPF GPi=Globus Pallidus Internal,FEC.FT.GPI (see Basal Ganglia) LHT=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN LHbL=Lateral Habenula Lateral Part,FAM.FD.LHB.LT LHbM=Lateral Habenula Medial Part,FAM.FD.LHB.MED NI=Incertus Nucleus,FAM.HT.TG.NI RMTg=Rostromedial Tegmental Nucleus,FEC.HT.TG.RMTG Raphe=Raphe Nuclei of Medulla,LMC.HL.RP (see Medullary Reticular Formation) SNc=Substantia Nigra Pars Compacta,FEC.FT.SNC (see Basal Ganglia) VTA=Ventral Tegmental Area,LMC.MM.VTA VTG=Ventral Tegmental Area,LMC.MM.VTG
- Both LHb and MHb control the dopaminergic and serotonergic systems - see Reference (CF.HB-DA5HT)
DBB=Diagonal Band of Broca,FAM.FT.SEP.DBB DRN=Dorsal Raphe Nucleus,LMC.MM.RP.DRN GPb=Dorsal Pallidum,FEC.FT.DP (see Basal Ganglia) IPN=Interpeduncular Nucleus,FEC.HT.TG.IPD LHA=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN LHbL=Lateral Habenula Lateral Part,FAM.FD.LHB.LT LHbM=Lateral Habenula Medial Part,FAM.FD.LHB.MED LPO=Ventrolateral Preoptic Nucleus,LAC.FD.HT.VLPO LS=Lateral Septal Nucleus,FAM.FT.SEP.LT MHb=Medial Habenula,FAM.FD.MHB MRN=Raphe Nuclei of Medulla,LMC.HL.RP (see Medullary Reticular Formation) MS=Medial Septal Nucleus,FAM.FT.SEP.MED PS=Posterior Septal Group,FAM.FT.SEP.PG (see Septal Nuclei) RMTg=Rostromedial Tegmental Nucleus,FEC.HT.TG.RMTG SNc=Substantia Nigra Pars Compacta,FEC.FT.SNC (see Basal Ganglia) VP=Ventral Pallidum,FEC.FT.VP (see Basal Ganglia) VTA=Ventral Tegmental Area,LMC.MM.VTA
- Fear regulation - see Reference (CF.FEAR-REG)
B=Basal Amygdaloid Nucleus,FAM.FT.AM.B (see Amygdala) CE=Central Amygdala,FAM.FT.AM.CEA (see Amygdala) Hippocampus=Hippocampus,FMM.FT.HC (see Hippocampal Formation) Hypothalamus=Hypothalamus,FD.HT ITC=Intercalated Amygdaloid Nuclei,FAM.FT.AM.ITC LA=Lateral Amygdaloid Nucleus,FAM.FT.AM.LA (see Amygdala) Striatum=Striatum,FEC.FT.ST (see Basal Ganglia) dlPFC=Mid-Dorsolateral Prefrontal Cortex,NDM.NC.AL.DLPFC (see Lateral Prefrontal Cortex) vmPFC=Ventromedial Prefrontal Cortex,NDM.NC.AL.VMPFC
- Glucose-sensing neural network - see Reference (CP.GLUCOSE)
ARC=Arcuate Nucleus of Hypothalamus,LAC.FD.HT.AR DMN=Dorsomedial Hypothalamic Nucleus,LAC.FD.HT.DM LHA=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN PVH=Paraventricular Nucleus,LAC.FD.HT.PV VMH=Ventromedial Hypothalamic Nucleus,LAC.FD.HT.VM
- Food-entrainable circadian oscillator - see Reference (CP.FOOD-OCSILLATOR)
DMH=Dorsomedial Hypothalamic Nucleus,LAC.FD.HT.DM LH=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN NTS=Solitary Nucleus,LPC.HL.SOL PBN=Parabrachial Nucleus,LPC.HT.PRF.PB PVH=Paraventricular Nucleus,LAC.FD.HT.PV SCN=Suprachiasmatic Nucleus,LAC.FD.HT.SCN
- Eating and sleeping to survive - see Reference (CP.DMH-CYCLES)
ARC=Arcuate Nucleus of Hypothalamus,LAC.FD.HT.AR DMH=Dorsomedial Hypothalamic Nucleus,LAC.FD.HT.DM LHA=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN MPO=Median Preoptic Nucleus,LAC.FD.HT.MPO PVH=Paraventricular Nucleus,LAC.FD.HT.PV SCN=Suprachiasmatic Nucleus,LAC.FD.HT.SCN VLPO=Ventrolateral Preoptic Nucleus,LAC.FD.HT.VLPO VMH=Ventromedial Hypothalamic Nucleus,LAC.FD.HT.VM
- Intrahypothalamic connections important for neural control of food intake and energy balance - see Reference (CL.INTRAHYPOTHALAMIC)
AH=Anterior Hypothalamic Nucleus,LAC.FD.HT.AH ARC=Arcuate Nucleus of Hypothalamus,LAC.FD.HT.AR DMN=Dorsomedial Hypothalamic Nucleus,LAC.FD.HT.DM LHA=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN MPOA=Median Preoptic Nucleus,LAC.FD.HT.MPO PA=Paraventricular Nucleus,LAC.FD.HT.PV SCH=Suprachiasmatic Nucleus,LAC.FD.HT.SCN SON=Supraoptic Nucleus,LAC.FD.HT.SO VMN=Ventromedial Hypothalamic Nucleus,LAC.FD.HT.VM
- Connectivity map of the habenula - see Reference (CF.HB-CONN)
CPu=Striatum,FEC.FT.ST (see Basal Ganglia) EP=Endopiriform Nucleus,FAM.FT.EPF Hippo=Hippocampus,FMM.FT.HC (see Hippocampal Formation) IPN=Interpeduncular Nucleus,FEC.HT.TG.IPD L=Lateral Habenula,FAM.FD.LHB (see Habenula) LH=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN M=Medial Habenula,FAM.FD.MHB NAc=Accumbens Nucleus,FEC.FT.ACC (see Basal Ganglia) PAG=Periaqueductal Gray Matter,LMC.MM.PAG Raphe=Raphe Nuclei of Medulla,LMC.HL.RP (see Medullary Reticular Formation) SNc=Substantia Nigra Pars Compacta,FEC.FT.SNC (see Basal Ganglia) Septum=Septal Nuclei,FAM.FT.SEP VTA=Ventral Tegmental Area,LMC.MM.VTA
- Amygdala and its network - see Reference (CF.AM-NET)
BLN=Parvicellular Basal Amygdaloid Nucleus,FAM.FT.AM.BP CEA=Central Amygdala,FAM.FT.AM.CEA (see Amygdala) EC=Entorhinal Cortex,FMM.NC.PH.ET (see Rhinal Cortex) HC=Hippocampus,FMM.FT.HC (see Hippocampal Formation) HTS=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN ITC=Inferotemporal Cortex,NSA.NC.IT.TE LA=Lateral Amygdaloid Nucleus,FAM.FT.AM.LA (see Amygdala) LHB=Lateral Habenula,FAM.FD.LHB (see Habenula) MD=Mediodorsal Nucleus of Thalamus,FD.TH.MD (see Cognitive Thalamus) MPFC=Orbitomedial Prefrontal Cortex,NC.AL.OMPFC NACC=Accumbens Nucleus,FEC.FT.ACC (see Basal Ganglia) PAG=Periaqueductal Gray Matter,LMC.MM.PAG RMTG=Rostromedial Tegmental Nucleus,FEC.HT.TG.RMTG STC=Wernicke's area A3,NSA.NC.STG.A3 VGDM=Vagus Nucleus,LAC.HL.VGN VTA=Ventral Tegmental Area,LMC.MM.VTA
References
(generated)
- http://neuroscience.uth.tmc.edu/s4/chapter04.html
- http://www.nature.com/nrendo/journal/v6/n8/fig_tab/nrendo.2010.93_F1.html
- http://journal.frontiersin.org/article/10.3389/fnhum.2013.00826/full
- http://www.nature.com/neuro/journal/v17/n9/fig_tab/nn.3779_F2.html
- https://brmlab.cz/project/brain_hacking/tdcs/pfc
- http://ajpregu.physiology.org/content/302/2/R215
- http://www.pnas.org/content/103/32/12150/F7.expansion.html
- http://www.dana.org/Publications/ReportDetails.aspx?id=44217
- http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.122.2314rep=rep1type=pdf
- http://jn.physiology.org/content/107/10/2633
- http://www.surgicalneurologyint.com/article.asp?issn=2152-7806;year=2012;volume=3;issue=2;spage=40;epage=46;aulast=Langevin