BrainRegionNDM NC AL DLPFCR
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Rostral Mid-Dorsolateral Prefrontal Cortex
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This page covers biological details of component Rostral Mid-Dorsolateral Prefrontal Cortex. Region is part of aHuman target integrated biological model.
- Top-down path to region: Cerebral Cortex -> Anterior Lobe (NC.LOBE.ANT) -> Prefrontal Cortex (NC.AL.PFC) -> Lateral Prefrontal Cortex (NC.AL.LPFC) -> Mid-Dorsolateral Prefrontal Cortex (NDM.NC.AL.DLPFC) -> Rostral Mid-Dorsolateral Prefrontal Cortex (NDM.NC.AL.DLPFCR) (see Mind Maps)
- Type: cortex
- Quality: L0
- Brain area: Neocortical Brain - Decision Making Area
- Brodmann ID: 46
- Role: cortex.generic
- Function: Cognitive control and monitoring to resolve conflict in information processing and competing response plans
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Components
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- no child items defined
Connectivity
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Inbound Region Connections:
Source Area | Source Region | Source Name | Type | Reference |
NCP | NCP.NC.MPL.RSC | Retrosplenial Cortex | feedforward-glu | Prefrontal Cortex (PFC) in emotional behavior (PCA -> LPFC, abstract) |
NDM | NDM.FD.TH.MDM | Medial Mediodorsal Nucleus of Thalamus | excitatory-glu | Prefrontal Cortex (PFC) in emotional behavior (TH -> LPFC, abstract) |
NDM.NC.AL.FPC | Lateral Frontopolar Cortex | feedforward-glu | Prefrontal Cortex (PFC) in emotional behavior (OPFC -> LPFC, abstract) | |
NDM.NC.AL.VACG | Ventral Anterior Cingulate Area | feedforward-glu | Role for serotonin in moral behavior (ACG -> LPFC, abstract) | |
NPE | NPE.NC.IPL.MST | Medial Superior Temporal Area | feedforward-glu | Cortico-Cortical Connectivity (PTHA -> PFC, abstract) |
NPE.NC.IPS.LIP | Lateral Intraparietal Sulcus | feedforward-glu | Summary of eye movement control (PEF -> DLPFC, abstract) |
Outbound Region Connections:
Target Area | Target Region | Target Name | Type | Reference |
NDM | NDM.NC.AL.DACG | Dorsal Anterior Cingulate Area | feedforward-glu | Prefrontal Cortex (PFC) in emotional behavior (LPFC -> ACG, abstract) |
NDM.NC.AL.VMPFC | Ventromedial Prefrontal Cortex | feedforward-glu | Fear regulation (dlPFC -> vmPFC, abstract) | |
NMA | NMA.NC.PMC.F7 | Dorsal Rostral Premotor Cortex | feedforward-glu | Prefrontal Cortex (PFC) in motor behavior (LPFC -> PMC, abstract) |
NMA.NC.SMC.F6 | Pre-Supplementary Motor Area | feedforward-glu | Primate Control of Grasping (46 -> F6, abstract) | |
NPE | NPE.NC.SMC.SEF | Supplementary Eye Field | feedforward-glu | 3 Visual Cortex Paths (LPC -> pre-SMA, abstract) |
Thirdparty Circuits
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- Global visual system - see Reference (CP.GLOBAL-VISUAL-SYSTEM)
ATH=Anterior Nucleus of Thalamus,FD.TH.AN (see Cognitive Thalamus) BGA=Basal Ganglia,FEC.FT.BG FrontalCortex=Anterior Lobe,NC.LOBE.ANT LGN=Lateral Geniculate Nucleus,NSA.FD.LGN OPN=Oculomotor Nucleus,LPC.MM.OCN ParietalCortex=Parietal Lobe,NC.LOBE.PAR Pulvinar=Pulvinar,FD.PV (see Sensory Thalamus) RF=Pontine Reticular Formation,HT.RF Retina=Retinal Nucleus,LPC.FD.RT SCi=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon) SCs=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon) SNc=Substantia Nigra Pars Compacta Lateral,FEC.FT.SNC.LT SNr=Substantia Nigra Pars Reticulata Dorsolateral,FEC.FT.SNR.DL SpinalCord=Lamina IX,SC.VH.L9 (see Anterior/Ventral Horn) Striatum=Striatum,FEC.FT.ST (see Basal Ganglia) VisualCortex=Occipital Lobe,NC.LOBE.OCC
- 3 Visual Cortex Paths - see Reference (CP.BASE-VISUAL-CORTEX-FLOWS)
IPL=Inferior Parietal Lobule,NC.IPL IPS=Intraparietal Sulcus,NSA.NC.IPS IT=Inferotemporal Area,NSA.NC.IT LPC=Mid-Dorsolateral Prefrontal Cortex,NDM.NC.AL.DLPFC (see Lateral Prefrontal Cortex) MI=Motor Cortex,NMA.NC.MC OCC=Occipital Lobe,NC.LOBE.OCC SPL=Superior Parietal Lobule,NC.SPL dPM=Dorsal Premotor Cortex,MCA.NC.DPMC (see Premotor Cortex) pre-SMA=Supplementary Motor Cortex,NMA.NC.SMC vPM=Ventral Premotor Cortex,MCA.NC.VPMC (see Premotor Cortex)
- Prefrontal Cortex (PFC) in motor behavior - see Reference (CM.PFC-MOTOR)
CN.PU=Striatum,FEC.FT.ST (see Basal Ganglia) CR=Cerebellar Complex,LLC.HT.CRC GP=Globus Pallidus,FEC.FT.GP (see Basal Ganglia) LPFC=Mid-Dorsolateral Prefrontal Cortex,NDM.NC.AL.DLPFC (see Lateral Prefrontal Cortex) MC=Motor Cortex,NMA.NC.MC PMC=Premotor Cortex,NC.PMC PN=Pontine Nuclear Complex,HT.PN (see Metencephalic Sensory Nuclei) SN=Substantia Nigra,FEC.FT.SN (see Basal Ganglia) TH=Ventral Thalamus,FD.TH.VTH (see Motor Thalamus)
- Primate Control of Grasping - see Reference (CM.GRASPING-CONTROL)
46=Mid-Dorsolateral Prefrontal Cortex,NDM.NC.AL.DLPFC (see Lateral Prefrontal Cortex) AIP=Anterior Intraparietal Sulcus,NSA.NC.IPS.AIP BG=Basal Ganglia,FEC.FT.BG BTH=Ventral Anterior Nucleus,NMA.FD.TH.VA F1=Motor Cortex,NMA.NC.MC F2=Dorsal Caudal Premotor Cortex,NMA.NC.PMC.F2 F4=Ventral Caudal Premotor Cortex,NMA.NC.PMC.F4 F5=Ventral Rostral Premotor Cortex,NMA.NC.PMC.F5 F6=Pre-Supplementary Motor Area,NMA.NC.SMC.F6 IT=Inferotemporal Area,NSA.NC.IT PIP=Posterior Eye Field,NPE.NC.IPS.PEF (see Intraparietal Sulcus) S1=Primary Somatosensory Cortex,NCP.NC.PG.S1 S2=Primary Somatosensory Cortex,NCP.NC.PG.S1 VC=Occipital Lobe,NC.LOBE.OCC VIP=Ventral Intraparietal Sulcus,NSA.NC.IPS.VIP
- Thalamocortical relationships - see Reference (CL.THALAMUS-PROJECTIONS)
A=Anterior Nucleus of Thalamus,FD.TH.AN (see Cognitive Thalamus) CM=Centromedian Nucleus of Thalamus,FEC.FD.TH.CM LD=Lateral Dorsal Nucleus of Thalamus,FMM.FD.TH.LD LGN=Lateral Geniculate Nucleus,NSA.FD.LGN LP=Lateral Posterior Nucleus of Thalamus,NPE.FD.TH.LP MD=Mediodorsal Nucleus of Thalamus,FD.TH.MD (see Cognitive Thalamus) MGN=Medial Geniculate Body,NSA.FD.TH.MGB P=Ventral Posterior Nuclei,NSA.FD.TH.VP (see Sensory Thalamus) VA=Ventral Anterior Nucleus,NMA.FD.TH.VA VL=Ventral Lateral Nucleus,NMA.FD.TH.VL VPL=Ventral Posterolateral Nucleus,NCP.FD.TH.VPL VPM=Ventral Posteromedial Nucleus,NCP.FD.TH.VPM pA=Posterior Cingulate Cortex,NCP.NC.MPL.PSCG pCM=Dorsal Putamen,FEC.FT.DPU (see Basal Ganglia) pLD=Anterior Cingulate Cortex,NC.AL.ACG (see Anterior Cingulate Area) pLGN=Primary Visual Cortex,NSA.NC.OCC.V1 pLP=Superior Parietal Lobule,NC.SPL pMD=Prefrontal Cortex,NC.AL.PFC pMGN=Primary Auditory Cortex,NSA.NC.TTG.A1 pP=Insular Cortex,NC.INS pVA=Supplementary Motor Cortex,NMA.NC.SMC pVL=Motor Cortex,NMA.NC.MC pVPL=Primary Somatosensory Cortex,NCP.NC.PG.S1 pVPM=Precentral Cortex,NCP.NC.PO.PCC s1A=Subiculum,FMM.FT.HF.SUB (see Hippocampal Formation) s1MD=Septal Nuclei,FAM.FT.SEP s1P=Central Cervical Nucleus,LPC.SC.IZ.CCV s1VL=Dentate Nucleus,LLC.HT.CR.DN s2A=Mammillary Body,FD.MB (see Hypothalamus) s2MD=Piriform Cortex,NSA.NC.PH.PIR s2P=Principal Trigeminal Nucleus,LPC.HT.PN.PTR s2VL=Basal Ganglia,FEC.FT.BG s3MD=Prefrontal Cortex,NC.AL.PFC sCM=Globus Pallidus Internal,FEC.FT.GPI (see Basal Ganglia) sLD=Superior Parietal Lobule,NC.SPL sLP=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon) sVA=Basal Ganglia,FEC.FT.BG sVPL=Marginal Nucleus,LPC.SC.PH.MG (see Posterior/Dorsal Horn) sVPM=Solitary Nucleus,LPC.HL.SOL
- Prefrontal Cortex (PFC) in emotional behavior - see Reference (CF.PFC-EMOTIONS)
ACG=Anterior Cingulate Cortex,NC.AL.ACG (see Anterior Cingulate Area) AM=Amygdala,FAM.FT.AM HCA=Hippocampus,FMM.FT.HC (see Hippocampal Formation) HT=Hypothalamus,FD.HT LPFC=Mid-Dorsolateral Prefrontal Cortex,NDM.NC.AL.DLPFC (see Lateral Prefrontal Cortex) OPFC=Orbitofrontal Cortex,NC.AL.OPFC (see Orbitomedial Prefrontal Cortex) PCA=Medial Parietal Lobule,NC.MPL PN=Pontine Nuclear Complex,HT.PN (see Metencephalic Sensory Nuclei) TH=Mediodorsal Nucleus of Thalamus,FD.TH.MD (see Cognitive Thalamus)
- Fear regulation - see Reference (CF.FEAR-REG)
B=Basal Amygdaloid Nucleus,FAM.FT.AM.B (see Amygdala) CE=Central Amygdala,FAM.FT.AM.CEA (see Amygdala) Hippocampus=Hippocampus,FMM.FT.HC (see Hippocampal Formation) Hypothalamus=Hypothalamus,FD.HT ITC=Intercalated Amygdaloid Nuclei,FAM.FT.AM.ITC LA=Lateral Amygdaloid Nucleus,FAM.FT.AM.LA (see Amygdala) Striatum=Striatum,FEC.FT.ST (see Basal Ganglia) dlPFC=Mid-Dorsolateral Prefrontal Cortex,NDM.NC.AL.DLPFC (see Lateral Prefrontal Cortex) vmPFC=Ventromedial Prefrontal Cortex,NDM.NC.AL.VMPFC
- Role for serotonin in moral behavior - see Reference (CF.EMOTIONAL-MODULATION)
ACG=Anterior Cingulate Cortex,NC.AL.ACG (see Anterior Cingulate Area) AMY=Amygdala,FAM.FT.AM HYP=Hypothalamus,FD.HT LPFC=Mid-Dorsolateral Prefrontal Cortex,NDM.NC.AL.DLPFC (see Lateral Prefrontal Cortex) OMPFC=Orbitofrontal Cortex,NC.AL.OPFC (see Orbitomedial Prefrontal Cortex)
References
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- http://www.sciencedirect.com/science/article/pii/S0959438808001566
- article:Biological/2008-dorsal-stream.pdf
- https://www.google.ru/search?hl=rutbo=ptbm=bksq=isbn:0080887988
- http://www.sciencedirect.com/science/article/pii/S0893608098000471
- http://what-when-how.com/neuroscience/the-thalamus-and-cerebral-cortex-integrative-systems-part-2/
- https://brmlab.cz/project/brain_hacking/tdcs/pfc
- http://www.pnas.org/content/107/40/17071/F1.expansion.html