BrainRegionFAM FT AM LAVM
Ventromedial Amygdaloid Nucleus
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This page covers biological details of component Ventromedial Amygdaloid Nucleus. Region is part of aHuman target integrated biological model.
- Top-down path to region: Forebrain Telencephalon -> Extended Amygdala (FAM.FT.EXTAM) -> Amygdala (FAM.FT.AM) -> Basolateral Nuclear Complex (FAM.FT.AM.BL) -> Lateral Amygdaloid Nucleus (FAM.FT.AM.LA) -> Ventromedial Amygdaloid Nucleus (FAM.FT.AM.LAVM) (see Mind Maps)
- Type: nucleus
- Brain area: Forebrain - Affective Motivations Area
- Role: processor.affective
- Function: conditional and unconditional convergence to affect polymodal memory formation
- Notes to function: LA3; projects to ET
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Components
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- no child items defined
Connectivity
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Inbound Region Connections:
Source Area | Source Region | Source Name | Type | Reference |
FAM | FAM.FT.AM.LADL | Dorsolateral Amygdaloid Nucleus | excitatory-glu | (unknown reference) |
FMM | FMM.FT.HC.CA1D | Distal CA1 of Hippocampus | excitatory-glu | Fear regulation (Hippocampus -> LA, abstract) |
FMM.NC.PH.LEC | Lateral Entorhinal Cortex | excitatory-glu | Simplified model of hippocampal formation anatomy (EC -> Amyg, abstract) | |
NSA | NSA.NC.STG.A3 | Wernicke's area A3 | excitatory-glu | Amygdala and its network (STC -> LA, abstract) |
Outbound Region Connections:
Target Area | Target Region | Target Name | Type | Reference |
FAM | FAM.FT.AM.AB | Accessory Basal Amygdaloid Nucleus | excitatory-glu | Summary of the main extra-amygdaloid and intra-amygdaloid connections in the rat (L -> AB, abstract) |
FAM.FT.AM.MPV | Medial Posterior Ventral Amygdaloid Nucleus | excitatory-glu | Summary of the main extra-amygdaloid and intra-amygdaloid connections in the rat (L -> M, abstract) | |
LPC | LPC.MM.CIC | Central Nucleus of Inferior Colliculus | excitatory-glu | Visual-Auditory Interactions in Tectum (AM -> IC, abstract) |
NDM | NDM.FD.TH.PV | Paraventricular Nucleus of Thalamus | excitatory-glu | Oculomotor decision-making (AMYG -> Thalamus, abstract) |
Thirdparty Circuits
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map: AM=Amygdala,FAM.FT.AM, AN=Anterior Nucleus of Thalamus,FD.TH.AN (Anteromedial Nucleus (NCP.FD.TH.AM), Anteroventral Nucleus (FMM.FD.TH.AV), Anterodorsal Nucleus (FMM.FD.TH.AD)), DG=Dentate Gyrus,FMM.FT.HC.DG, DorsalCingulate=Dorsal Anterior Cingulate Area,NDM.NC.AL.DACG, EC=Entorhinal Cortex,FMM.NC.PH.ET (Lateral Entorhinal Cortex (FMM.NC.PH.LEC), Medial Entorhinal Cortex (FMM.NC.PH.MEC)), HC=Subiculum,FMM.FT.HF.SUB (Proximal Subiculum (FMM.FT.HF.SUBP), Middle Subiculum (FMM.FT.HF.SUBM), Distal Subiculum (FMM.FT.HF.SUBD)), MB=Medial Mammillary Nucleus,FMM.FD.MB.MMB, PosteriorCingulate=Posterior Cingulate Cortex,NCP.NC.MPL.PSCG, SEP=Septal Nuclei,FAM.FT.SEP, SUB=Subiculum,FMM.FT.HF.SUB (Proximal Subiculum (FMM.FT.HF.SUBP), Middle Subiculum (FMM.FT.HF.SUBM), Distal Subiculum (FMM.FT.HF.SUBD)), VentralCingulate=Ventral Anterior Cingulate Area,NDM.NC.AL.VACG
map: AC=Primary Auditory Cortex,NSA.NC.TTG.A1, AM=Amygdala,FAM.FT.AM, CN=Cochlear Nucleus,LPC.HL.COCH (Dorsal Cochlear Nucleus (LPC.HL.DCOCH), Ventral Cochlear Nucleus (LPC.HL.VCOCH)), IC=Inferior Colliculus,ABA.MM.IC (Central Nucleus of Inferior Colliculus (LPC.MM.CIC), External Nucleus of Inferior Colliculus (LRC.MM.EIC)), MGB=Medial Geniculate Body,NSA.FD.TH.MGB, OC=Superior Olivary Complex,LPC.MM.SOC, PM=Premotor Cortex,NC.PMC, SC=Superior Colliculus,MM.SC (Superficial Superior Colliculus (LRC.MM.SC.SUP), Intermediate Superior Colliculus (LRC.MM.SC.INT), Deep Superior Colliculus (LRC.MM.SC.DEEP))
map: AMYG=Amygdala,FAM.FT.AM, CGa=Anterior Cingulate Cortex,NC.AL.ACG (Ventral Anterior Cingulate Area (NDM.NC.AL.VACG), Dorsal Anterior Cingulate Area (NDM.NC.AL.DACG), Subgenual Cingulate Cortex (NCP.NC.AL.SGCG)), CGp=Posterior Cingulate Cortex,NCP.NC.MPL.PSCG, Caudate=Caudate Nucleus,FEC.FT.CN (Caudate Nucleus Head (FEC.FT.CN.HD), Caudate Nucleus Body (FEC.FT.CN.BD), Caudate Nucleus Tail (FEC.FT.CN.TL)), FEF=Frontal Eye Field,NMA.NC.PMC.FEF (Caudal Frontal Eye Field (NPE.NC.PMC.CFEF), Anterior Frontal Eye Field (NPE.NC.PMC.AFEF)), LIP=Lateral Intraparietal Sulcus,NPE.NC.IPS.LIP, NAC=Accumbens Nucleus,FEC.FT.ACC (Nucleus Accumbens Core (FEC.FT.ACC.CORE), Nucleus Accumbens Shell (FEC.FT.ACC.SH)), OFC=Orbitofrontal Cortex,NC.AL.OPFC (Lateral Frontopolar Cortex (NDM.NC.AL.FPC), Most Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCR), Sulcal Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCS), Medial Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCM), Lateral Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCL)), PFC=Mid-Dorsolateral Prefrontal Cortex,NDM.NC.AL.DLPFC (Rostral Mid-Dorsolateral Prefrontal Cortex (NDM.NC.AL.DLPFCR), Lateral Mid-Dorsolateral Prefrontal Cortex (NDM.NC.AL.DLPFCL)), SC=Superior Colliculus,MM.SC (Superficial Superior Colliculus (LRC.MM.SC.SUP), Intermediate Superior Colliculus (LRC.MM.SC.INT), Deep Superior Colliculus (LRC.MM.SC.DEEP)), SEF=Supplementary Eye Field,NPE.NC.SMC.SEF, SNc=Substantia Nigra Pars Compacta Lateral,FEC.FT.SNC.LT, SNr=Substantia Nigra Pars Reticulata Dorsolateral,FEC.FT.SNR.DL, Thalamus=Thalamus,FD.TH (Lateral Geniculate Nucleus (NSA.FD.LGN), Medial Geniculate Body (NSA.FD.TH.MGB), Ventral Posteroinferior Nucleus (NCP.FD.TH.VPI), Ventral Posterolateral Nucleus (NCP.FD.TH.VPL), Ventral Posteromedial Nucleus (NCP.FD.TH.VPM), Inferior Pulvinar (NSA.FD.TH.IPV), Lateral Pulvinar (NSA.FD.TH.LPV), Medial Pulvinar (NPE.FD.TH.MPV), Oral Pulvinar (NPE.FD.TH.OPV), Limitans Nucleus of Thalamus (NCP.FD.TH.LI), Suprageniculate Nucleus of Thalamus (NSA.FD.TH.SG), Submedial Nucleus of Thalamus (NDM.FD.TH.SM), Ventral Anterior Nucleus (NMA.FD.TH.VA), Ventral Lateral Nucleus (NMA.FD.TH.VL), Lateral Dorsal Nucleus of Thalamus (FMM.FD.TH.LD), Lateral Posterior Nucleus of Thalamus (NPE.FD.TH.LP), Medial Mediodorsal Nucleus of Thalamus (NDM.FD.TH.MDM), Central Mediodorsal Nucleus of Thalamus (NCP.FD.TH.MDC), Lateral Mediodorsal Nucleus of Thalamus (NMA.FD.TH.MDL), Anteromedial Nucleus (NCP.FD.TH.AM), Anteroventral Nucleus (FMM.FD.TH.AV), Anterodorsal Nucleus (FMM.FD.TH.AD), Rostral Intralaminar Nuclear Group of Thalamus (NCP.FD.TH.RIL), Centromedian Nucleus of Thalamus (FEC.FD.TH.CM), Parafascicular Nucleus of Thalamus (FEC.FD.TH.PF), Paratenial Nucleus of Thalamus (FAM.FD.TH.PT), Paraventricular Nucleus of Thalamus (NDM.FD.TH.PV), Reuniens Nucleus of Thalamus (FMM.FD.TH.RE), Rhomboidal Nucleus of Thalamus (FMM.FD.TH.RH), Subfascicular Nucleus of Thalamus (LLC.FD.TH.SF)), VTA=Ventral Tegmental Area,LMC.MM.VTA
map: AB=Accessory Basal Amygdaloid Nucleus,FAM.FT.AM.AB, B=Basal Amygdaloid Nucleus,FAM.FT.AM.B (Parvicellular Basal Amygdaloid Nucleus (FAM.FT.AM.BP), Magnocellular Basal Amygdaloid Nucleus (FAM.FT.AM.BM)), CE=Central Amygdala,FAM.FT.AM.CEA (Central Amygdaloid Nucleus, capsular subdivision (FAM.FT.AM.CEC), Central Amygdaloid Nucleus, lateral subdivision (FAM.FT.AM.CEL), Medial Central Amygdaloid Nucleus (FAM.FT.AM.CEM)), L=Lateral Amygdaloid Nucleus,FAM.FT.AM.LA (Dorsolateral Amygdaloid Nucleus (FAM.FT.AM.LADL), Ventrolateral Amygdaloid Nucleus (FAM.FT.AM.LAVL), Ventromedial Amygdaloid Nucleus (FAM.FT.AM.LAVM)), M=Medial Amygdala,FAM.FT.AM.M (Medial Anterior Amygdaloid Nucleus (FAM.FT.AM.MEA), Medial Posterior Dorsal Amygdaloid Nucleus (FAM.FT.AM.MPD), Medial Posterior Ventral Amygdaloid Nucleus (FAM.FT.AM.MPV))
map: BLA=Basolateral Nuclear Complex,FAM.FT.AM.BL (Dorsolateral Amygdaloid Nucleus (FAM.FT.AM.LADL), Ventrolateral Amygdaloid Nucleus (FAM.FT.AM.LAVL), Ventromedial Amygdaloid Nucleus (FAM.FT.AM.LAVM), Parvicellular Basal Amygdaloid Nucleus (FAM.FT.AM.BP), Magnocellular Basal Amygdaloid Nucleus (FAM.FT.AM.BM), Accessory Basal Amygdaloid Nucleus (FAM.FT.AM.AB)), CA1=Ventrolateral Cornu Ammonis of Hippocampus,FMM.FT.HC.CA1 (Proximal CA1 of Hippocampus (FMM.FT.HC.CA1P), Middle CA1 of Hippocampus (FMM.FT.HC.CA1M), Distal CA1 of Hippocampus (FMM.FT.HC.CA1D)), CA3=Dorsomedial Cornu Ammonis of Hippocampus,FMM.FT.HC.CA3 (Proximal CA3 of Hippocampus (FMM.FT.HC.CA3P), Middle CA3 of Hippocampus (FMM.FT.HC.CA3M), Distal CA3 of Hippocampus (FMM.FT.HC.CA3D)), DG=Dentate Gyrus,FMM.FT.HC.DG, ET=Entorhinal Cortex,FMM.NC.PH.ET (Lateral Entorhinal Cortex (FMM.NC.PH.LEC), Medial Entorhinal Cortex (FMM.NC.PH.MEC))
References
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- http://highered.mcgraw-hill.com/sites/dl/free/0071402357/156721/figure350_1.html
- http://f1000research.com/articles/2-20/v1
- http://www.springerimages.com/Images/LifeSciences/1-10.1007_s00359-004-0565-9-0
- http://journal.frontiersin.org/article/10.3389/fphar.2014.00068/full
- http://journal.frontiersin.org/Journal/10.3389/fpsyt.2013.00061/full