BrainAreaLRC
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Motor Reflex Area
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Contents
Local Circuits
(generated)
| ID | Name | Regions | Quality |
| LGP | Gait and Posture Control | LRC.MM.CNF, LRC.MM.SCNF | L0 |
| LLP | Vestibulocerebellar Locomotion | LRC.HL.RF.SLRN, LRC.HT.CR.FG, LRC.HT.CR.FN, LRC.HT.CR.VM | L0 |
| LRB | Breathing and Swallowing Reflexes | LRC.HL.RA, LRC.HL.TGS.PA5, LRC.HT.KFN, LRC.HT.NSC, LRC.HT.PRF.CRF, LRC.HT.PRF.PVR | L0 |
| LRF | Frontal Visual Reflexes | LRC.MM.CJ, LRC.MM.DSCH, LRC.MM.RIMLF, LRC.MM.RP.RIP | L0 |
| LRM | Multisensory Orienting Reflexes | LRC.MM.EIC, LRC.MM.SC.DEEP, LRC.MM.SC.INT | L0 |
| LRP | Postural Control Reflexes | LRC.HL.INM, LRC.HL.NPH, LRC.HL.PRF.GCR, LRC.HL.RF.MED, LRC.HT.PRF.RPO, LRC.MM.PT.PR | L0 |
| LRV | Direct Visual Reflexes | LRC.MM.PT.NOT, LRC.MM.PT.PON, LRC.MM.PT.PTA, LRC.MM.PT.SL, LRC.MM.SC.SUP | L0 |
Gait and Posture Control
| Component ID | Component Name | Type | Service | Function | Comments | Quality |
| LRC.MM.CNF | Cuneiform Nucleus | nucleus | LLE | Passive coping strategy to novel, painful or threatening stimuli | L0 | |
| LRC.MM.SCNF | Subcuneiform Nucleus | nucleus | LLE | Initiation of gait, feedback control of saccade accuracy | L0 |
Internal Region Connections:
- no connections
External Inbound Region Connections:
| Source Area | Local Region | Source Region | Source Name | Type | Role | Reference |
| Subcortical | ||||||
| LPC | LRC.MM.CNF | LPC.SC.PH.CL | Clarke Nucleus | nucleus-nucleus | uncertain | (unknown reference) |
| LRC | LRC.MM.SCNF | LRC.HL.NPH | Prepositus Nucleus | nucleus-nucleus | uncertain | (unknown reference) |
| LRC.HL.PRF.GCR | Gigantocellular Reticular Nucleus | nucleus-nucleus | uncertain | (unknown reference) | ||
| LRC.MM.RP.RIP | Raphe Interpositus Nucleus | nucleus-nucleus | uncertain | (unknown reference) |
External Outbound Region Connections:
| Target Area | Local Region | Target Region | Target Name | Type | Role | Reference |
| Subcortical | ||||||
| LAC | LRC.MM.CNF | LAC.HL.VGN | Vagus Nucleus | nucleus-nucleus | uncertain | (unknown reference) |
| LMC | LRC.MM.SCNF | LMC.HL.RP.MG | Raphe Magnus Nucleus | nucleus-nucleus | uncertain | (unknown reference) |
| LMC.HP.RP.PRN | Pontine Raphe Nucleus | nucleus-nucleus | uncertain | (unknown reference) | ||
| LRC | LRC.MM.CNF | LRC.HL.PRF.GCR | Gigantocellular Reticular Nucleus | nucleus-nucleus | uncertain | (unknown reference) |
| LRC.HT.KFN | Kolliker-Fuse Nucleus | nucleus-nucleus | uncertain | (unknown reference) |
Vestibulocerebellar Locomotion
| Component ID | Component Name | Type | Service | Function | Comments | Quality |
| LRC.HL.RF.SLRN | Lateral Reticular Nucleus, Subtrigeminal | nucleus | LLI | vestibular input | L0 | |
| LRC.HT.CR.FG | Fastigual Nucleus | nucleus | LLC | rostral - interprets body motion and places it on spatial planes to estimate movement of body through space; caudal - saccadic eye movements |
L0 | |
| LRC.HT.CR.FN | Cerebellar Flocconodular Lobe | nucleus | LLC | regulates balance | L0 | |
| LRC.HT.CR.VM | Cerebellar Vermis | cortex | LLC | balance and spatial orientation, gait | L0 |
Internal Region Connections:
| Source Region | Target Region | Type | Role | Reference |
| LRC.HL.RF.SLRN | LRC.HT.CR.FN | nucleus-nucleus | uncertain | (unknown reference) |
| LRC.HT.CR.VM | LRC.HT.CR.FG | allocortex-nucleus-gaba | uncertain | Cerebellum functional divisions (CRV -> FG) |
External Inbound Region Connections:
| Source Area | Local Region | Source Region | Source Name | Type | Role | Reference |
| Subcortical | ||||||
| LLC | LRC.HT.CR.FG | LLC.HT.CR.PV | Cerebellar Paravermis | allocortex-nucleus | uncertain | Cerebellum functional divisions (CRS -> FG) |
| LRC.HT.CR.FN | LLC.HT.PRF.RTMG | Pontine Reticulotegmental Nucleus | nucleus-nucleus-gaba | uncertain | (unknown reference) | |
| LRC.HT.CR.VM | LLC.HL.IO | Inferior Olivary Nucleus | nucleus-allocortex | uncertain | Cerebellum functional divisions (IO -> CRV) | |
| LLC.HT.PRF.RTMG | Pontine Reticulotegmental Nucleus | nucleus-allocortex-gaba | uncertain | (unknown reference) | ||
| LPC | LRC.HL.RF.SLRN | LPC.HT.LVBN | Lateral Vestibular Nucleus | nucleus-nucleus | uncertain | (unknown reference) |
| LRC.HT.CR.FN | LPC.HT.IVBN | Inferior Vestibular Nuclei | nucleus-nucleus | uncertain | (unknown reference) | |
| LPC.PN.SG.SVB | Vestibular Ganglion - Saccule Neurons | ganglion-nucleus | uncertain | (unknown reference) | ||
| LRC.HT.CR.VM | LPC.HT.MVBN | Medial Vestibular Nucleus | nucleus-allocortex | uncertain | Cerebellum functional divisions (VB -> CRV, abstract) | |
| LPC.SC.IZ.CCV | Central Cervical Nucleus | nucleus-allocortex | uncertain | (unknown reference) |
External Outbound Region Connections:
| Target Area | Local Region | Target Region | Target Name | Type | Role | Reference |
| Subcortical | ||||||
| LPC | LRC.HT.CR.FG | LPC.HT.LVBN | Lateral Vestibular Nucleus | nucleus-nucleus | uncertain | Cerebellum functional divisions (FG -> VB, abstract) |
| LRC.HT.CR.FN | LPC.HT.MVBN | Medial Vestibular Nucleus | nucleus-nucleus-gaba | uncertain | (unknown reference) | |
| LPC.HT.SVBN | Superior Vestibular Nucleus | nucleus-nucleus-gaba | uncertain | (unknown reference) | ||
| LRC | LRC.HT.CR.FG | LRC.HT.PRF.CRF | Caudal Pontine Reticular Nucleus | nucleus-nucleus | uncertain | Cerebellum functional divisions (FG -> RF, abstract) |
| LRC.MM.PT.PR | Principal Pretectal Nucleus | nucleus-nucleus | uncertain | (unknown reference) |
Breathing and Swallowing Reflexes
| Component ID | Component Name | Type | Service | Function | Comments | Quality |
| LRC.HL.RA | Retroambigualis Nucleus | nucleus | LRM | Groups of premotor interneurons producing detailed motor actions | L0 | |
| LRC.HL.TGS.PA5 | Paratrigeminal Nucleus | nucleus | LRS | Orofacial nociceptive sensory processing | L0 | |
| LRC.HT.KFN | Kolliker-Fuse Nucleus | nucleus | LRM | Control of protruder tongue muscles contraction to maintain respiration | L0 | |
| LRC.HT.NSC | Nucleus Subceruleus | nucleus | LRM | Tongue control | L0 | |
| LRC.HT.PRF.CRF | Caudal Pontine Reticular Nucleus | nucleus | LRM | Mediate head movements | L0 | |
| LRC.HT.PRF.PVR | Parvocellular Reticular Nucleus | nucleus | LRM | Flow of respiratory current out of organism | L0 |
Internal Region Connections:
| Source Region | Target Region | Type | Role | Reference |
| LRC.HT.KFN | LRC.HL.RA | nucleus-nucleus | uncertain | (unknown reference) |
External Inbound Region Connections:
| Source Area | Local Region | Source Region | Source Name | Type | Role | Reference |
| Cortical | ||||||
| NCP | LRC.HL.TGS.PA5 | NCP.NC.PG.S1 | Primary Somatosensory Cortex | neocortex-nucleus | uncertain | (unknown reference) |
| NMA | LRC.HT.PRF.CRF | NMA.NC.MC | Motor Cortex | neocortex-nucleus | uncertain | Motor neurons control (CTX -> PRF, abstract) |
| NMA.NC.SMC.F3 | Supplementary Motor Area | neocortex-nucleus | uncertain | Motor neurons control (CTX -> PRF, abstract) | ||
| Subcortical | ||||||
| FEC | LRC.HT.PRF.PVR | FEC.FT.SNC.MED | Substantia Nigra Pars Compacta Medial | nucleus-nucleus-DA | uncertain | (unknown reference) |
| LMC | LRC.HL.RA | LMC.MM.PAG | Periaqueductal Gray Matter | nucleus-nucleus-ENK | uncertain | (unknown reference) |
| LRC.HT.NSC | LMC.MM.PAG | Periaqueductal Gray Matter | nucleus-nucleus-ENK | uncertain | (unknown reference) | |
| LPC | LRC.HL.RA | LPC.HL.SOL | Solitary Nucleus | nucleus-nucleus | uncertain | (unknown reference) |
| LRC.HT.KFN | LPC.HL.SOL | Solitary Nucleus | nucleus-nucleus | uncertain | (unknown reference) | |
| LRC.HT.PRF.CRF | LPC.HT.IVBN | Inferior Vestibular Nuclei | nucleus-nucleus | uncertain | Vestibulo-ocular reflex (VOR) (VestibularNuclei -> PPRF, abstract) | |
| LRC | LRC.HT.KFN | LRC.MM.CNF | Cuneiform Nucleus | nucleus-nucleus | uncertain | (unknown reference) |
| LRC.HT.PRF.CRF | LRC.HT.CR.FG | Fastigual Nucleus | nucleus-nucleus | uncertain | Cerebellum functional divisions (FG -> RF, abstract) |
External Outbound Region Connections:
| Target Area | Local Region | Target Region | Target Name | Type | Role | Reference |
| Subcortical | ||||||
| FMM | LRC.HT.NSC | FMM.FT.HC.DG | Dentate Gyrus | nucleus-allocortex | uncertain | (unknown reference) |
| LPC | LRC.HL.RA | LPC.HL.AMB | Ambiguus Nucleus | nucleus-nucleus | uncertain | (unknown reference) |
| LPC.SC.VH.ONF | Onuf's Nucleus | nucleus-nucleus | uncertain | (unknown reference) | ||
| LPC.SC.VH.PHR | Phrenic Nucleus | nucleus-nucleus | uncertain | (unknown reference) | ||
| LRC.HL.TGS.PA5 | LPC.HT.FCM | Facial Motor Nucleus | nucleus-nucleus | uncertain | (unknown reference) | |
| LRC.HT.KFN | LPC.HL.HYG | Hypoglossal Motor Nucleus | nucleus-nucleus | uncertain | (unknown reference) | |
| LRC.HT.NSC | LPC.HL.HYG | Hypoglossal Motor Nucleus | nucleus-nucleus | uncertain | (unknown reference) | |
| LRC.HT.PRF.CRF | LPC.HL.AMB | Ambiguus Nucleus | nucleus-nucleus | uncertain | Vocal Control (RF -> NucleusAmbiguus, abstract) | |
| LPC.HL.HYG | Hypoglossal Motor Nucleus | nucleus-nucleus | uncertain | Vocal Control (RF -> NucleusXII, abstract) | ||
| LPC.HT.FCM | Facial Motor Nucleus | nucleus-nucleus | uncertain | Vocal Control (RF -> MotorVII, abstract) | ||
| LPC.HT.TRM | Trigeminal Motor Nucleus | nucleus-nucleus | uncertain | Vocal Control (RF -> MotorV, abstract) | ||
| LRC.HT.PRF.PVR | LPC.HT.FCM | Facial Motor Nucleus | nucleus-nucleus | uncertain | Vocal Control (RF -> MotorVII, abstract) | |
| LPC.HT.TRM | Trigeminal Motor Nucleus | nucleus-nucleus | uncertain | Vocal Control (RF -> MotorV, abstract) |
Frontal Visual Reflexes
| Component ID | Component Name | Type | Service | Function | Comments | Quality |
| LRC.MM.CJ | Cajal Nucleus | nucleus | LRM | Integration of head and eye movements, controls downward vertical gaze | Relay of extrapyramidal control for automatic movements |
L0 |
| LRC.MM.DSCH | Darkschewitsch Nucleus | nucleus | LRM | Mediate the consensual pupillary light reflex | Accessory oculomotor nucleus | L0 |
| LRC.MM.RIMLF | Rostral Interstitial Nucleus of MLF | nucleus | LRM | Integration of head and eye movements, controls upward vertical gaze | L0 | |
| LRC.MM.RP.RIP | Raphe Interpositus Nucleus | nucleus | LUS | Premotor network for saccades | L0 |
Internal Region Connections:
- no connections
External Inbound Region Connections:
| Source Area | Local Region | Source Region | Source Name | Type | Role | Reference |
| Cortical | ||||||
| NPE | LRC.MM.CJ | NPE.NC.IPS.LIP | Lateral Intraparietal Sulcus | neocortex-nucleus | uncertain | Vision Components (VAC -> SOA, abstract) |
| NPE.NC.OCC.V3D | Dorsal Associative Visual Cortex | neocortex-nucleus | uncertain | Eye blink reflex and pupillary light reflex (VAC -> SupraOculomotor, abstract) | ||
| NPE.NC.PMC.AFEF | Anterior Frontal Eye Field | neocortex-nucleus | uncertain | Summary of eye movement control (FEF -> riMLF, abstract) | ||
| LRC.MM.DSCH | NPE.NC.PMC.AFEF | Anterior Frontal Eye Field | neocortex-nucleus | uncertain | (unknown reference) | |
| LRC.MM.RIMLF | NPE.NC.IPS.LIP | Lateral Intraparietal Sulcus | neocortex-nucleus | uncertain | Vision Components (VAC -> SOA, abstract) | |
| NPE.NC.OCC.V3D | Dorsal Associative Visual Cortex | neocortex-nucleus | uncertain | Eye blink reflex and pupillary light reflex (VAC -> SupraOculomotor, abstract) | ||
| LRC.MM.RP.RIP | NPE.NC.SMC.SEF | Supplementary Eye Field | neocortex-nucleus | uncertain | Horizontal saccades and smooth pursuit movements (FEFSEF -> RIP, abstract) | |
| Subcortical | ||||||
| LLC | LRC.MM.DSCH | LLC.HT.CR.GN | Globose Nucleus | nucleus-nucleus | uncertain | (unknown reference) |
| LPC | LRC.MM.CJ | LPC.HL.VCOCH | Ventral Cochlear Nucleus | nucleus-nucleus | uncertain | (unknown reference) |
| LRC.MM.DSCH | LPC.HT.MVBN | Medial Vestibular Nucleus | nucleus-nucleus | uncertain | (unknown reference) | |
| LRC | LRC.MM.CJ | LRC.MM.SC.DEEP | Deep Superior Colliculus | nucleus-nucleus | uncertain | Summary of eye movement control (SC -> riMLF, abstract) |
| LRC.MM.RP.RIP | LRC.MM.SC.SUP | Superficial Superior Colliculus | nucleus-nucleus | uncertain | Horizontal saccades and smooth pursuit movements (SC -> RIP, abstract) |
External Outbound Region Connections:
| Target Area | Local Region | Target Region | Target Name | Type | Role | Reference |
| Subcortical | ||||||
| LAC | LRC.MM.DSCH | LAC.MM.EWN | Edinger-Westphal Nucleus | nucleus-nucleus | uncertain | Eye blink reflex and pupillary light reflex (SupraOculomotor -> EWN, abstract) |
| LLC | LRC.MM.DSCH | LLC.HL.IO | Inferior Olivary Nucleus | nucleus-nucleus | uncertain | (unknown reference) |
| LPC | LRC.MM.CJ | LPC.MM.OCN | Oculomotor Nucleus | nucleus-nucleus | uncertain | Eye blink reflex and pupillary light reflex (SupraOculomotor -> Oculomotor, abstract) |
| LPC.MM.TRH | Trochlear Nucleus | nucleus-nucleus | uncertain | (unknown reference) | ||
| LRC.MM.RIMLF | LPC.MM.OCN | Oculomotor Nucleus | nucleus-nucleus | uncertain | Eye blink reflex and pupillary light reflex (SupraOculomotor -> Oculomotor, abstract) | |
| LRC | LRC.MM.RP.RIP | LRC.HT.PRF.RPO | Oral Pontine Reticular Nucleus | nucleus-nucleus | uncertain | Horizontal saccades and smooth pursuit movements (RIP -> PPRF, abstract) |
| LRC.MM.SCNF | Subcuneiform Nucleus | nucleus-nucleus | uncertain | (unknown reference) |
Multisensory Orienting Reflexes
| Component ID | Component Name | Type | Service | Function | Comments | Quality |
| LRC.MM.EIC | External Nucleus of Inferior Colliculus | nucleus | LSC | Middle ear reflex | L0 | |
| LRC.MM.SC.DEEP | Deep Superior Colliculus | nucleus | LRC | Head and eye attention to non-visual stimuli | L0 | |
| LRC.MM.SC.INT | Intermediate Superior Colliculus | nucleus | LRC | Sensimotor integration for orienting | L0 |
Internal Region Connections:
| Source Region | Target Region | Type | Role | Reference |
| LRC.MM.EIC | LRC.MM.SC.INT | nucleus-nucleus | uncertain | Five Parallel Auditory Pathways (ICx -> SC, abstract) |
| LRC.MM.SC.INT | LRC.MM.SC.DEEP | nucleus-nucleus | uncertain | Global visual system (SCs -> SCi, abstract) |
External Inbound Region Connections:
| Source Area | Local Region | Source Region | Source Name | Type | Role | Reference |
| Cortical | ||||||
| NPE | LRC.MM.SC.INT | NPE.NC.PMC.AFEF | Anterior Frontal Eye Field | neocortex-nucleus | uncertain | Summary of eye movement control (FEF -> SC, abstract) |
| Subcortical | ||||||
| FEC | LRC.MM.SC.INT | FEC.FT.SNR.DL | Substantia Nigra Pars Reticulata Dorsolateral | nucleus-nucleus-gaba | uncertain | Global visual system (SNr -> SCi, abstract) |
| FEC.FT.SNR.VL | Substantia Nigra Pars Reticulata Ventrolateral | nucleus-nucleus-gaba | uncertain | Saccadic Vision (BG -> SCi, abstract) | ||
| FEC.HT.TG.IPD | Interpeduncular Nucleus | nucleus-nucleus-ACh | uncertain | (unknown reference) | ||
| LLC | LRC.MM.SC.DEEP | LLC.HT.CR.GN | Globose Nucleus | nucleus-nucleus | uncertain | (unknown reference) |
| LRC.MM.SC.INT | LLC.HT.BPN | Basilar Pontine Nuclei | nucleus-nucleus | uncertain | (unknown reference) | |
| LLC.HT.CR.EN | Emboliform Nucleus | nucleus-nucleus | uncertain | (unknown reference) | ||
| LMC | LRC.MM.SC.INT | LMC.HT.TG.PPN | Pedunculopontine Tegmental Nuclei | nucleus-nucleus | uncertain | Geniculate and Extyrageniculate Paths (PPN -> SC, abstract) |
| LPC | LRC.MM.EIC | LPC.MM.CIC | Central Nucleus of Inferior Colliculus | nucleus-nucleus | uncertain | Five Parallel Auditory Pathways (ICC -> ICx, abstract) |
| LRC.MM.SC.INT | LPC.HL.CU | Cuneate Nucleus | nucleus-nucleus | uncertain | (unknown reference) | |
| LPC.HL.GR | Gracile Nucleus | nucleus-nucleus | uncertain | (unknown reference) | ||
| LPC.HL.TGS.STR | Spinal Trigeminal Nucleus | nucleus-nucleus | uncertain | (unknown reference) | ||
| LRC | LRC.MM.SC.INT | LRC.MM.SC.SUP | Superficial Superior Colliculus | nucleus-nucleus | uncertain | Global visual system (SCs -> SCi, abstract) |
External Outbound Region Connections:
Postural Control Reflexes
| Component ID | Component Name | Type | Service | Function | Comments | Quality |
| LRC.HL.INM | Intercalated Nucleus of Medulla | nucleus | LRC | Coordinate tongue movements, vestibuloocular reflex | L0 | |
| LRC.HL.NPH | Prepositus Nucleus | nucleus | LLE | Integrate PPRF phasic signal to provide tonic signal of abducens | L0 | |
| LRC.HL.PRF.GCR | Gigantocellular Reticular Nucleus | nucleus | LRM | Vasodepressor center | L0 | |
| LRC.HL.RF.MED | Central Medullary Reticular Nucleus | nucleus | LLE | Somatic motor control, cardiovascular control, pain modulation, sleep and consciousness, habituation |
L0 | |
| LRC.HT.PRF.RPO | Oral Pontine Reticular Nucleus | nucleus | LRM | Mediation of changing to and from REM sleep | L0 | |
| LRC.MM.PT.PR | Principal Pretectal Nucleus | nucleus | LRM | Pupillary light reflex | Medial pretectal nucleus | L0 |
Internal Region Connections:
| Source Region | Target Region | Type | Role | Reference |
| LRC.HL.NPH | LRC.HL.INM | nucleus-nucleus | uncertain | (unknown reference) |
| LRC.HL.PRF.GCR | LRC.HL.RF.MED | nucleus-nucleus | uncertain | (unknown reference) |
External Inbound Region Connections:
| Source Area | Local Region | Source Region | Source Name | Type | Role | Reference |
| Cortical | ||||||
| NMA | LRC.HL.PRF.GCR | NMA.NC.SMC.F3 | Supplementary Motor Area | neocortex-nucleus | uncertain | Motor neurons control (CTX -> MRF, abstract) |
| NPE | LRC.HL.PRF.GCR | NPE.NC.PMC.AFEF | Anterior Frontal Eye Field | neocortex-nucleus | uncertain | Motor neurons control (CTX -> MRF, abstract) |
| LRC.HT.PRF.RPO | NPE.NC.BRA.PO | Broca's Area Pars Opercularis | neocortex-nucleus | uncertain | Motor neurons control (CTX -> PRF, abstract) | |
| NPE.NC.PMC.AFEF | Anterior Frontal Eye Field | neocortex-nucleus | uncertain | Motor neurons control (CTX -> PRF, abstract) | ||
| NSA | LRC.HT.PRF.RPO | NSA.NC.IT.TE | Inferotemporal Cortex | neocortex-nucleus | uncertain | Saccades and smooth movements (TEF -> DLPN, abstract) |
| Subcortical | ||||||
| LMC | LRC.HL.NPH | LMC.HT.TG.LDT | Laterodorsal Tegmental Nucleus | nucleus-nucleus-ACh | uncertain | Head Direction Cell Circuit (DTN -> NPRP) |
| LPC | LRC.HL.INM | LPC.HT.MVBN | Medial Vestibular Nucleus | nucleus-nucleus | uncertain | (unknown reference) |
| LRC.HL.NPH | LPC.HT.MVBN | Medial Vestibular Nucleus | nucleus-nucleus | uncertain | Head Direction Cell Circuit (MVSN -> NPRP) | |
| LRC.HL.PRF.GCR | LPC.HL.TGS.STR | Spinal Trigeminal Nucleus | nucleus-nucleus | uncertain | (unknown reference) | |
| LRC | LRC.HL.PRF.GCR | LRC.MM.CNF | Cuneiform Nucleus | nucleus-nucleus | uncertain | (unknown reference) |
| LRC.HT.PRF.RPO | LRC.MM.RP.RIP | Raphe Interpositus Nucleus | nucleus-nucleus | uncertain | Horizontal saccades and smooth pursuit movements (RIP -> PPRF, abstract) | |
| LRC.MM.SC.DEEP | Deep Superior Colliculus | nucleus-nucleus | uncertain | Summary of eye movement control (SC -> PPRF, abstract) | ||
| LRC.MM.PT.PR | LRC.HT.CR.FG | Fastigual Nucleus | nucleus-nucleus | uncertain | (unknown reference) |
External Outbound Region Connections:
| Target Area | Local Region | Target Region | Target Name | Type | Role | Reference |
| Cortical | ||||||
| NSA | LRC.HL.NPH | NSA.FD.TH.SG | Suprageniculate Nucleus of Thalamus | nucleus-nucleus | uncertain | Head Direction Cell Circuit (NPRP -> SUPGEN) |
| Subcortical | ||||||
| FAM | LRC.HT.PRF.RPO | FAM.HT.TG.NI | Incertus Nucleus | nucleus-nucleus | uncertain | (unknown reference) |
| LAC | LRC.HL.INM | LAC.FD.HT.PN | Posterior Hypothalamic Nucleus | nucleus-nucleus | uncertain | (unknown reference) |
| LRC.MM.PT.PR | LAC.MM.EWN | Edinger-Westphal Nucleus | nucleus-nucleus | uncertain | Eye blink reflex and pupillary light reflex (Pretectum -> EWN, abstract) | |
| LLC | LRC.HT.PRF.RPO | LLC.HT.CR.CC | Cerebellar Lateral Lobe | nucleus-allocortex | uncertain | Saccades and smooth movements (DLPN -> CR, abstract) |
| LMC | LRC.HL.NPH | LMC.HT.TG.LDT | Laterodorsal Tegmental Nucleus | nucleus-nucleus | uncertain | (unknown reference) |
| LRC.HL.RF.MED | LMC.HT.LC | Locus Coeruleus | nucleus-nucleus | uncertain | (unknown reference) | |
| LPC | LRC.HL.PRF.GCR | LPC.SC.VH.PL | Posterolateral Nucleus | nucleus-nucleus | uncertain | Motor neurons control (MRF -> EGMN, abstract) |
| LPC.SC.VH.PM | Posteromedial Nucleus | nucleus-nucleus | uncertain | Motor neurons control (MRF -> EGMN, abstract) | ||
| LRC.HL.RF.MED | LPC.SC.VH.VM | Ventromedial Nucleus | nucleus-nucleus | uncertain | Motor neurons control (MRF -> EGMN, abstract) | |
| LRC.HT.PRF.RPO | LPC.HT.ABD | Abducens Nucleus | nucleus-nucleus | uncertain | Vestibulo-ocular reflex (VOR) (PPRF -> Abducens, abstract) | |
| LPC.HT.IVBN | Inferior Vestibular Nuclei | nucleus-nucleus | uncertain | (unknown reference) | ||
| LPC.MM.OCN | Oculomotor Nucleus | nucleus-nucleus | uncertain | Global visual system (RF -> OPN, abstract) | ||
| LPC.SC.VH.SAN | Spinal Accessory Nucleus | nucleus-nucleus | uncertain | Cerebellum functional divisions (RF -> SCM, abstract) | ||
| LPC.SC.VH.VL | Ventrolateral Nucleus | nucleus-nucleus | uncertain | Cerebellum functional divisions (RF -> SCM, abstract) | ||
| LPC.SC.VH.VM | Ventromedial Nucleus | nucleus-nucleus | uncertain | Cerebellum functional divisions (RF -> SCM, abstract) | ||
| LRC | LRC.HL.NPH | LRC.MM.PT.NOT | Nucleus of Optic Tract | nucleus-nucleus | uncertain | (unknown reference) |
| LRC.MM.SCNF | Subcuneiform Nucleus | nucleus-nucleus | uncertain | (unknown reference) | ||
| LRC.HL.PRF.GCR | LRC.MM.SCNF | Subcuneiform Nucleus | nucleus-nucleus | uncertain | (unknown reference) |
Direct Visual Reflexes
| Component ID | Component Name | Type | Service | Function | Comments | Quality |
| LRC.MM.PT.NOT | Nucleus of Optic Tract | nucleus | LRS | Encode retinal error information during smooth pursuit eye movements | L0 | |
| LRC.MM.PT.PON | Pretectal Olivary Nucleus | nucleus | LRS | Pupillary light reflex and modulating subcortical nuclei involved in circadian rhythms |
L0 | |
| LRC.MM.PT.PTA | Anterior Pretectum Nucleus | nucleus | LLI | Mediate somatosensory and nociceptive information | Nucleus of pretectal area | L0 |
| LRC.MM.PT.SL | Sublentiform Nucleus | nucleus | LRS | Accomodation reflex | Posterior pretectal nucleus | L0 |
| LRC.MM.SC.SUP | Superficial Superior Colliculus | nucleus | LRC | Head and eye attention to visual stimuli | L0 |
Internal Region Connections:
| Source Region | Target Region | Type | Role | Reference |
| LRC.MM.PT.NOT | LRC.MM.SC.SUP | nucleus-nucleus | uncertain | (unknown reference) |
External Inbound Region Connections:
| Source Area | Local Region | Source Region | Source Name | Type | Role | Reference |
| Cortical | ||||||
| NPE | LRC.MM.SC.SUP | NPE.NC.IPL.MST | Medial Superior Temporal Area | neocortex-nucleus | uncertain | Global visual system (ParietalCortex -> SCi, abstract) |
| NPE.NC.IPS.LIP | Lateral Intraparietal Sulcus | neocortex-nucleus | uncertain | Summary of eye movement control (PEF -> SC, abstract) | ||
| NSA | LRC.MM.PT.NOT | NSA.FD.LGN | Lateral Geniculate Nucleus | nucleus-nucleus | uncertain | (unknown reference) |
| LRC.MM.PT.SL | NSA.NC.OCC.V1 | Primary Visual Cortex | neocortex-nucleus | uncertain | (unknown reference) | |
| LRC.MM.SC.SUP | NSA.NC.OCC.V1 | Primary Visual Cortex | neocortex-nucleus | uncertain | Global visual system (VisualCortex -> SCs, abstract) | |
| NSA.NC.OCC.V2TN | Secondary Visual Cortex, Thin Stripe | neocortex-nucleus | uncertain | Global visual system (VisualCortex -> SCs, abstract) | ||
| Subcortical | ||||||
| LAC | LRC.MM.PT.NOT | LAC.FD.HT.SCN | Suprachiasmatic Nucleus | nucleus-nucleus | uncertain | (unknown reference) |
| LPC | LRC.MM.PT.NOT | LPC.FD.RT | Retinal Nucleus | nucleus-nucleus | uncertain | Targets of retina neurons (Retina -> Pretectum, abstract) |
| LRC.MM.PT.PON | LPC.FD.RT | Retinal Nucleus | nucleus-nucleus | uncertain | Effect of light on pupil diameter (RET -> OPN) | |
| LRC.MM.PT.SL | LPC.FD.RT | Retinal Nucleus | nucleus-nucleus | uncertain | Targets of retina neurons (Retina -> Pretectum, abstract) | |
| LRC.MM.SC.SUP | LPC.FD.RT | Retinal Nucleus | nucleus-nucleus | uncertain | Geniculate and Extyrageniculate Paths (Retina -> SC, abstract) | |
| LRC | LRC.MM.PT.NOT | LRC.HL.NPH | Prepositus Nucleus | nucleus-nucleus | uncertain | (unknown reference) |
External Outbound Region Connections:
| Target Area | Local Region | Target Region | Target Name | Type | Role | Reference |
| Cortical | ||||||
| NPE | LRC.MM.PT.PTA | NPE.FD.TH.LP | Lateral Posterior Nucleus of Thalamus | nucleus-nucleus | uncertain | (unknown reference) |
| NPE.FD.TH.MPV | Medial Pulvinar | nucleus-nucleus | uncertain | (unknown reference) | ||
| LRC.MM.PT.SL | NPE.FD.TH.LP | Lateral Posterior Nucleus of Thalamus | nucleus-nucleus | uncertain | (unknown reference) | |
| NPE.FD.TH.MPV | Medial Pulvinar | nucleus-nucleus | uncertain | (unknown reference) | ||
| LRC.MM.SC.SUP | NPE.FD.TH.LP | Lateral Posterior Nucleus of Thalamus | nucleus-nucleus | uncertain | Thalamocortical relationships (sLP -> LP, abstract) | |
| NSA | LRC.MM.PT.PON | NSA.FD.LGN | Lateral Geniculate Nucleus | nucleus-nucleus | uncertain | (unknown reference) |
| LRC.MM.SC.SUP | NSA.FD.LGN | Lateral Geniculate Nucleus | nucleus-nucleus | uncertain | Global visual system (SCs -> LGN, abstract) | |
| NSA.FD.TH.IPV | Inferior Pulvinar | nucleus-nucleus | uncertain | Global visual system (SCs -> Pulvinar, abstract) | ||
| NSA.FD.TH.LPV | Lateral Pulvinar | nucleus-nucleus | uncertain | Global visual system (SCs -> Pulvinar, abstract) | ||
| Subcortical | ||||||
| FEC | LRC.MM.PT.PTA | FEC.FD.STN.ICD | Subthalamic Nucleus Internal Caudal | nucleus-nucleus | uncertain | (unknown reference) |
| LAC | LRC.MM.PT.PON | LAC.MM.EWN | Edinger-Westphal Nucleus | nucleus-nucleus | uncertain | Effect of light on pupil diameter (OPN -> EW) |
| LRC.MM.PT.SL | LAC.MM.EWN | Edinger-Westphal Nucleus | nucleus-nucleus | uncertain | Eye blink reflex and pupillary light reflex (Pretectum -> EWN, abstract) | |
| LPC | LRC.MM.PT.SL | LPC.MM.OCN | Oculomotor Nucleus | nucleus-nucleus | uncertain | (unknown reference) |
| LRC | LRC.MM.SC.SUP | LRC.MM.RP.RIP | Raphe Interpositus Nucleus | nucleus-nucleus | uncertain | Horizontal saccades and smooth pursuit movements (SC -> RIP, abstract) |
| LRC.MM.SC.INT | Intermediate Superior Colliculus | nucleus-nucleus | uncertain | Global visual system (SCs -> SCi, abstract) |
Thirdparty Circuits
(generated)
- Saccades and smooth movements (unknown reference) (CP.SACCADIC-VOLUNTARY-AND-PURSUIT)
CN=Caudate Nucleus,FEC.FT.CN (see Basal Ganglia) CR=Cerebellum,LLC.HT.CR (see Cerebellar Complex) DLPN=Oral Pontine Reticular Nucleus,LRC.HT.PRF.RPO Extrastriate=Associative Visual Cortex,NPE.NC.OCC.V3 (see Occipital Lobe) FEF=Frontal Eye Field,NMA.NC.PMC.FEF (see Premotor Cortex) PPC=Posterior Eye Field,NPE.NC.IPS.PEF (see Intraparietal Sulcus) PPRF=Paramedian Pontine Reticular Formation,HT.PRF.PPRF (see Pontine Reticular Formation) SC=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon) SN=Substantia Nigra,FEC.FT.SN (see Basal Ganglia) Striate=Primary Visual Cortex,NSA.NC.OCC.V1 TEF=Inferotemporal Area,NSA.NC.IT VGC=Cajal Nucleus,LRC.MM.CJ Vestibular=Lateral Vestibular Nucleus,LPC.HT.LVBN
- Cerebellum functional divisions - see Reference (CM.CR-DECUSSATION)
CCV=Central Cervical Nucleus,LPC.SC.IZ.CCV CRP=Cerebellar Lateral Lobe,LLC.HT.CR.CC CRS=Cerebellar Paravermis,LLC.HT.CR.PV CRV=Cerebellar Vermis,LRC.HT.CR.VM CTX=Anterior Lobe,NC.LOBE.ANT DN=Dentate Nucleus,LLC.HT.CR.DN FG=Fastigual Nucleus,LRC.HT.CR.FG IO=Inferior Olivary Nucleus,LLC.HL.IO IP=Interposed Nucleus,LLC.HT.CR.IP (see Cerebellar Complex) LT=Dentate Nucleus,LLC.HT.CR.DN PNN=Basilar Pontine Nuclei,LLC.HT.BPN RD=Red Nucleus,LLC.MM.RD RF=Pontine Reticular Formation,HT.RF SCM=Anterior/Ventral Horn,SC.VH SCS=Proprius Nucleus,LPC.SC.PH.NP SCSD=Clarke Nucleus,LPC.SC.PH.CL VB=Vestibular Nuclei,LPC.HT.VBN VBG=Vestibular Ganglion,LPC.PN.SG.VB VL=Ventral Lateral Nucleus,NMA.FD.TH.VL
- Horizontal saccades and smooth pursuit movements - see Reference (CP.VISION-SACCADES)
Bechterew=Pontine Reticulotegmental Nucleus,LLC.HT.PRF.RTMG CR=Cerebellum,LLC.HT.CR (see Cerebellar Complex) FEFSEF=Anterior Lobe,NC.LOBE.ANT LGB=Lateral Geniculate Nucleus,NSA.FD.LGN PPRF=Paramedian Pontine Reticular Formation,HT.PRF.PPRF (see Pontine Reticular Formation) PrimaryVisual=Primary Visual Cortex,NSA.NC.OCC.V1 RIP=Raphe Interpositus Nucleus,LRC.MM.RP.RIP SC=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon) Striatum=Striatum,FEC.FT.ST (see Basal Ganglia) Vestibular=Superior Vestibular Nucleus,LPC.HT.SVBN VisualAssociation=Caudal Precuneus,NPE.NC.SPL.PG
- Effect of light on pupil diameter - see Reference (CP.PUPIL-REFLEX)
DMH=Dorsomedial Hypothalamic Nucleus,LAC.FD.HT.DM EW=Edinger-Westphal Nucleus,LAC.MM.EWN EYE=Eye,TARGET.TSA.EYE GC=Ciliary Ganglion,LAC.PN.PSYM.CLG IML=Ciliospinal Center,LAC.SC.IZ.CSC LC=Locus Coeruleus,LMC.HT.LC OPN=Pretectal Olivary Nucleus,LRC.MM.PT.PON PVN=Paraventricular Nucleus,LAC.FD.HT.PV RET=Retinal Nucleus,LPC.FD.RT SCG=Superior Cervical Ganglion,LAC.PN.SYM.SCG SCN=Suprachiasmatic Nucleus,LAC.FD.HT.SCN
- Summary of eye movement control - see Reference (CP.EYE-FIELDS)
DLPFC=Mid-Dorsolateral Prefrontal Cortex,NDM.NC.AL.DLPFC (see Lateral Prefrontal Cortex) FEF=Frontal Eye Field,NMA.NC.PMC.FEF (see Premotor Cortex) PEF=Posterior Eye Field,NPE.NC.IPS.PEF (see Intraparietal Sulcus) PPRF=Paramedian Pontine Reticular Formation,HT.PRF.PPRF (see Pontine Reticular Formation) SC=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon) SEF=Supplementary Eye Field,NPE.NC.SMC.SEF riMLF=Cajal Nucleus,LRC.MM.CJ
- Motor neurons control - see Reference (CM.CR-MN)
CR=Cerebellum,LLC.HT.CR (see Cerebellar Complex) CTX=Anterior Lobe,NC.LOBE.ANT EAMN=Anterior/Ventral Horn,SC.VH EGMN=Anterior/Ventral Horn,SC.VH FAMN=Anterior/Ventral Horn,SC.VH FG=Fastigual Nucleus,LRC.HT.CR.FG IP=Interposed Nucleus,LLC.HT.CR.IP (see Cerebellar Complex) LT=Dentate Nucleus,LLC.HT.CR.DN MRF=Medullary Reticular Formation,HL.RF PRF=Pontine Reticular Formation,HT.RF RD=Red Nucleus,LLC.MM.RD VB=Vestibular Nuclei,LPC.HT.VBN
- Head Direction Cell Circuit - see Reference (CT.HEAD-DIRECTION)
AD=Anterodorsal Nucleus,FMM.FD.TH.AD DTN=Laterodorsal Tegmental Nucleus,LMC.HT.TG.DTG EC=Entorhinal Cortex,FMM.NC.PH.ET (see Rhinal Cortex) HC=Hippocampus,FMM.FT.HC (see Hippocampal Formation) IPD=Interpeduncular Nucleus,FEC.HT.TG.IPD LD=Lateral Dorsal Nucleus of Thalamus,FMM.FD.TH.LD LHAB=Habenula,FAM.FD.HB LMB=Lateral Mammillary Nucleus,FMM.FD.MB.LMB MVSN=Medial Vestibular Nucleus,LPC.HT.MVBN NPRP=Prepositus Nucleus,LRC.HL.NPH PC=Parietal Lobe,NC.LOBE.PAR PRHC=Postrhinal Cortex,FMM.NC.PH.POR PSUB=Postsubiculum,FMM.NC.PH.POS RSP=Retrosplenial Cortex,NCP.NC.MPL.RSC SUPGEN=Suprageniculate Nucleus of Thalamus,NSA.FD.TH.SG VC=Occipital Lobe,NC.LOBE.OCC
References
(generated)
- http://instruct.uwo.ca/anatomy/530/cblm.htm
- http://www.sciencedirect.com/science/article/pii/S0006899301025987
- http://journal.frontiersin.org/article/10.3389/fnint.2012.00094/full
- http://www.cixip.com/index.php/page/content/id/1190
- http://openagrosrl.com/www/page/292/
- http://www.scholarpedia.org/article/Head_direction_cells
