Difference between revisions of "BrainRegionFEC FT ACC SH"
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<pre style="color: green">Nucleus Accumbens Shell</pre> | <pre style="color: green">Nucleus Accumbens Shell</pre> | ||
@@[[Home]] -> [[BiologicalLifeResearch]] -> [[BrainAreaFEC]] -> [[BrainRegionFEC_FT_ACC_SH]] | @@[[Home]] -> [[BiologicalLifeResearch]] -> [[BrainAreaFEC]] -> [[BrainRegionFEC_FT_ACC_SH]] | ||
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* '''Top-down path to region''': Forebrain Telencephalon -> [[BrainCenterFEC_FT_BG|Basal Ganglia]] (FEC.FT.BG) -> Striatum (FEC.FT.ST) -> Ventral Striatum (FEC.FT.VST) -> Accumbens Nucleus (FEC.FT.ACC) -> [[BrainRegionFEC_FT_ACC_SH|Nucleus Accumbens Shell]] (FEC.FT.ACC.SH) (see [[OverallMindMaps|Mind Maps]]) | * '''Top-down path to region''': Forebrain Telencephalon -> [[BrainCenterFEC_FT_BG|Basal Ganglia]] (FEC.FT.BG) -> Striatum (FEC.FT.ST) -> Ventral Striatum (FEC.FT.VST) -> Accumbens Nucleus (FEC.FT.ACC) -> [[BrainRegionFEC_FT_ACC_SH|Nucleus Accumbens Shell]] (FEC.FT.ACC.SH) (see [[OverallMindMaps|Mind Maps]]) | ||
* '''Type''': nucleus | * '''Type''': nucleus | ||
| − | * '''Brain area''': [[BrainAreaFEC|Forebrain - Execution Control Area]] | + | * '''Quality''': L0 |
| + | * '''Brain area''': [[BrainAreaFEC|Forebrain - Execution Control Area]] (FEC) | ||
| + | * '''Area circuit''': Cognitive Motivational Salience (FECAF) | ||
* '''Role''': basal.ganglia.striatum | * '''Role''': basal.ganglia.striatum | ||
* '''Function''': cognitive processing of motivational salience (wanting) as well as reward and reinforcement effects | * '''Function''': cognitive processing of motivational salience (wanting) as well as reward and reinforcement effects | ||
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{| class=wikitable width=80% | {| class=wikitable width=80% | ||
| − | | '''Source Area''' || '''Source Region''' || '''Source Name''' || '''Type''' || '''Reference''' | + | | '''Source Area''' || '''Source Region''' || '''Source Name''' || '''Type''' || '''Role''' || '''Reference''' |
|- | |- | ||
| − | | [[BrainAreaFEC|FEC]] || [[BrainRegionFEC_FT_SNC_LT|FEC.FT.SNC.LT]] || Substantia Nigra Pars Compacta Lateral || modulatory-da || [http://jn.physiology.org/content/107/10/2633 Connectivity map of the habenula (SNc -> CPu, abstract)] | + | | [[BrainAreaFEC|FEC]] || [[BrainRegionFEC_FT_SNC_LT|FEC.FT.SNC.LT]] || Substantia Nigra Pars Compacta Lateral || modulatory-da || uncertain ||[http://jn.physiology.org/content/107/10/2633 Connectivity map of the habenula (SNc -> CPu, abstract)] |
|- | |- | ||
| − | | || [[BrainRegionFEC_FT_SNC_MED|FEC.FT.SNC.MED]] || Substantia Nigra Pars Compacta Medial || modulatory-da || [http://jn.physiology.org/content/107/10/2633 Connectivity map of the habenula (SNc -> CPu, abstract)] | + | | || [[BrainRegionFEC_FT_SNC_MED|FEC.FT.SNC.MED]] || Substantia Nigra Pars Compacta Medial || modulatory-da || uncertain ||[http://jn.physiology.org/content/107/10/2633 Connectivity map of the habenula (SNc -> CPu, abstract)] |
|- | |- | ||
| − | | [[BrainAreaLAC|LAC]] || [[BrainRegionLAC_FD_HT_VM|LAC.FD.HT.VM]] || Ventromedial Hypothalamic Nucleus || excitatory-glu || [http://www.nature.com/nrendo/journal/v6/n8/fig_tab/nrendo.2010.93_F1.html Bowels control brain: gut hormones and obesity (VMN -> NAc, abstract)] | + | | [[BrainAreaLAC|LAC]] || [[BrainRegionLAC_FD_HT_VM|LAC.FD.HT.VM]] || Ventromedial Hypothalamic Nucleus || excitatory-glu || uncertain ||[http://www.nature.com/nrendo/journal/v6/n8/fig_tab/nrendo.2010.93_F1.html Bowels control brain: gut hormones and obesity (VMN -> NAc, abstract)] |
|- | |- | ||
| − | | [[BrainAreaLMC|LMC]] || [[BrainRegionLMC_MM_VTA|LMC.MM.VTA]] || Ventral Tegmental Area || modulatory-da || [http://www.impulsecontroldisorders.org/html/cravings.html Craving (VTA -> NACC, abstract)] | + | | [[BrainAreaLMC|LMC]] || [[BrainRegionLMC_MM_VTA|LMC.MM.VTA]] || Ventral Tegmental Area || modulatory-da || uncertain ||[http://www.impulsecontroldisorders.org/html/cravings.html Craving (VTA -> NACC, abstract)] |
|- | |- | ||
| − | | [[BrainAreaLPC|LPC]] || [[BrainRegionLPC_HL_SOL|LPC.HL.SOL]] || Solitary Nucleus || excitatory-glu || [http://www.nature.com/nrendo/journal/v6/n8/fig_tab/nrendo.2010.93_F1.html Bowels control brain: gut hormones and obesity (NTS -> NAc, abstract)] | + | | [[BrainAreaLPC|LPC]] || [[BrainRegionLPC_HL_SOL|LPC.HL.SOL]] || Solitary Nucleus || excitatory-glu || uncertain ||[http://www.nature.com/nrendo/journal/v6/n8/fig_tab/nrendo.2010.93_F1.html Bowels control brain: gut hormones and obesity (NTS -> NAc, abstract)] |
|- | |- | ||
| − | | || [[BrainRegionLPC_HT_PRF_PB|LPC.HT.PRF.PB]] || Parabrachial Nucleus || excitatory-glu || [http://www.nature.com/nrendo/journal/v6/n8/fig_tab/nrendo.2010.93_F1.html Bowels control brain: gut hormones and obesity (PBN -> NAc, abstract)] | + | | || [[BrainRegionLPC_HT_PRF_PB|LPC.HT.PRF.PB]] || Parabrachial Nucleus || excitatory-glu || uncertain ||[http://www.nature.com/nrendo/journal/v6/n8/fig_tab/nrendo.2010.93_F1.html Bowels control brain: gut hormones and obesity (PBN -> NAc, abstract)] |
|- | |- | ||
| − | | [[BrainAreaNCP|NCP]] || [[BrainRegionNCP_NC_MPL_PSCG|NCP.NC.MPL.PSCG]] || Posterior Cingulate Cortex || excitatory-glu || (unknown reference) | + | | [[BrainAreaNCP|NCP]] || [[BrainRegionNCP_NC_MPL_PSCG|NCP.NC.MPL.PSCG]] || Posterior Cingulate Cortex || excitatory-glu || uncertain ||(unknown reference) |
|- | |- | ||
| − | | [[BrainAreaNDM|NDM]] || [[BrainRegionNDM_NC_AL_VACG|NDM.NC.AL.VACG]] || Ventral Anterior Cingulate Area || excitatory-glu || [http://www.sciencedirect.com/science/article/pii/S0959438808001566 Global visual system (FrontalCortex -> BGA, abstract)] | + | | [[BrainAreaNDM|NDM]] || [[BrainRegionNDM_NC_AL_VACG|NDM.NC.AL.VACG]] || Ventral Anterior Cingulate Area || excitatory-glu || uncertain ||[http://www.sciencedirect.com/science/article/pii/S0959438808001566 Global visual system (FrontalCortex -> BGA, abstract)] |
|} | |} | ||
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{| class=wikitable width=80% | {| class=wikitable width=80% | ||
| − | | '''Target Area''' || '''Target Region''' || '''Target Name''' || '''Type''' || '''Reference''' | + | | '''Target Area''' || '''Target Region''' || '''Target Name''' || '''Type''' || '''Role''' || '''Reference''' |
|- | |- | ||
| − | | [[BrainAreaFAM|FAM]] || [[BrainRegionFAM_FD_MHB|FAM.FD.MHB]] || Medial Habenula || inhibitory-gaba || [http://jn.physiology.org/content/107/10/2633 Connectivity map of the habenula (NAc -> M, abstract)] | + | | [[BrainAreaFAM|FAM]] || [[BrainRegionFAM_FD_MHB|FAM.FD.MHB]] || Medial Habenula || inhibitory-gaba || uncertain || [http://jn.physiology.org/content/107/10/2633 Connectivity map of the habenula (NAc -> M, abstract)] |
|- | |- | ||
| − | | [[BrainAreaFEC|FEC]] || [[BrainRegionFEC_FT_IPAC_LT|FEC.FT.IPAC.LT]] || Lateral Interstitial Anterior Commissural Nucleus || inhibitory-gaba || (unknown reference) | + | | [[BrainAreaFEC|FEC]] || [[BrainRegionFEC_FT_IPAC_LT|FEC.FT.IPAC.LT]] || Lateral Interstitial Anterior Commissural Nucleus || inhibitory-gaba || uncertain || (unknown reference) |
|- | |- | ||
| − | | || [[BrainRegionFEC_FT_VP_VM|FEC.FT.VP.VM]] || Ventral Pallidum Ventromedial || inhibitory-gaba || [http://www.impulsecontroldisorders.org/html/cravings.html Craving (NACC -> VPAL, abstract)] | + | | || [[BrainRegionFEC_FT_VP_VM|FEC.FT.VP.VM]] || Ventral Pallidum Ventromedial || inhibitory-gaba || uncertain || [http://www.impulsecontroldisorders.org/html/cravings.html Craving (NACC -> VPAL, abstract)] |
|- | |- | ||
| − | | [[BrainAreaLAC|LAC]] || [[BrainRegionLAC_FD_HT_LTN|LAC.FD.HT.LTN]] || Lateral Hypothalamic Nucleus || inhibitory-gaba || (unknown reference) | + | | [[BrainAreaLAC|LAC]] || [[BrainRegionLAC_FD_HT_LTN|LAC.FD.HT.LTN]] || Lateral Hypothalamic Nucleus || inhibitory-gaba || uncertain || (unknown reference) |
|- | |- | ||
| − | | [[BrainAreaLMC|LMC]] || [[BrainRegionLMC_FT_NBM|LMC.FT.NBM]] || Basal Nucleus of Meynert || inhibitory-gaba || [http://www.expertsmind.com/topic/emotion/affective-basal-ganglia-circuit-93570.aspx Affective basal ganglia circuit (NACC -> nBM, abstract)] | + | | [[BrainAreaLMC|LMC]] || [[BrainRegionLMC_FT_NBM|LMC.FT.NBM]] || Basal Nucleus of Meynert || inhibitory-gaba || uncertain || [http://www.expertsmind.com/topic/emotion/affective-basal-ganglia-circuit-93570.aspx Affective basal ganglia circuit (NACC -> nBM, abstract)] |
|} | |} | ||
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(generated) | (generated) | ||
| − | * [http://neurowiki2012.wikispaces.com/file/view/Reward_circuit.jpg/315908202/Reward_circuit.jpg Reward circuit of human brain] - see [http://neurowiki2012.wikispaces.com/Presynaptic+Mechanisms+of+Synaptic+Plasticity Reference] | + | * [http://neurowiki2012.wikispaces.com/file/view/Reward_circuit.jpg/315908202/Reward_circuit.jpg Reward circuit of human brain] - see [http://neurowiki2012.wikispaces.com/Presynaptic+Mechanisms+of+Synaptic+Plasticity Reference] (CF.REWARD-CIRCUIT) |
| − | <img src="http://ahuman.org/svn/ahwiki/images/ext/284310755a3e65beb74826e15beade5d.jpg" alt="unavailable" style="max-width: 100%;"> | + | AM=[[BrainCenterFAM_FT_AM|Amygdala,FAM.FT.AM]] |
| + | HC=Hippocampus,FMM.FT.HC (see [[BrainCenterFMM_FT_HF|Hippocampal Formation]]) | ||
| + | NACC=Accumbens Nucleus,FEC.FT.ACC (see [[BrainCenterFEC_FT_BG|Basal Ganglia]]) | ||
| + | PFC=Orbitofrontal Cortex,NC.AL.OPFC (see [[BrainCenterNC_AL_OMPFC|Orbitomedial Prefrontal Cortex]]) | ||
| + | VPAL=Ventral Pallidum,FEC.FT.VP (see [[BrainCenterFEC_FT_BG|Basal Ganglia]]) | ||
| + | VTA=[[BrainRegionLMC_MM_VTA|Ventral Tegmental Area,LMC.MM.VTA]] | ||
| + | <img src="http://ahuman.org/svn/ahwiki/images/ext/284310755a3e65beb74826e15beade5d.jpg" alt=alt="unavailable" style="max-width: 100%;"> | ||
| − | * [http://d2avczb82rh8fa.cloudfront.net/content/jn/107/10/2633/F1.large.jpg Connectivity map of the habenula] - see [http://jn.physiology.org/content/107/10/2633 Reference] | + | * [http://d2avczb82rh8fa.cloudfront.net/content/jn/107/10/2633/F1.large.jpg Connectivity map of the habenula] - see [http://jn.physiology.org/content/107/10/2633 Reference] (CF.HB-CONN) |
| − | <img src="http://ahuman.org/svn/ahwiki/images/ext/213e030f063f9640f8ace79244e622d1.jpg" alt="unavailable" style="max-width: 100%;"> | + | CPu=Striatum,FEC.FT.ST (see [[BrainCenterFEC_FT_BG|Basal Ganglia]]) |
| + | EP=[[BrainRegionFAM_FT_EPF|Endopiriform Nucleus,FAM.FT.EPF]] | ||
| + | Hippo=Hippocampus,FMM.FT.HC (see [[BrainCenterFMM_FT_HF|Hippocampal Formation]]) | ||
| + | IPN=[[BrainRegionFEC_HT_TG_IPD|Interpeduncular Nucleus,FEC.HT.TG.IPD]] | ||
| + | L=Lateral Habenula,FAM.FD.LHB (see [[BrainCenterFAM_FD_HB|Habenula]]) | ||
| + | LH=[[BrainRegionLAC_FD_HT_LTN|Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN]] | ||
| + | M=[[BrainRegionFAM_FD_MHB|Medial Habenula,FAM.FD.MHB]] | ||
| + | NAc=Accumbens Nucleus,FEC.FT.ACC (see [[BrainCenterFEC_FT_BG|Basal Ganglia]]) | ||
| + | PAG=[[BrainRegionLMC_MM_PAG|Periaqueductal Gray Matter,LMC.MM.PAG]] | ||
| + | Raphe=Raphe Nuclei of Medulla,LMC.HL.RP (see [[BrainCenterHL_RF|Medullary Reticular Formation]]) | ||
| + | SNc=Substantia Nigra Pars Compacta,FEC.FT.SNC (see [[BrainCenterFEC_FT_BG|Basal Ganglia]]) | ||
| + | Septum=[[BrainCenterFAM_FT_SEP|Septal Nuclei,FAM.FT.SEP]] | ||
| + | VTA=[[BrainRegionLMC_MM_VTA|Ventral Tegmental Area,LMC.MM.VTA]] | ||
| + | <img src="http://ahuman.org/svn/ahwiki/images/ext/213e030f063f9640f8ace79244e622d1.jpg" alt=alt="unavailable" style="max-width: 100%;"> | ||
| − | * [http://www.impulsecontroldisorders.org/images/8-Urges9proof.jpg Craving] - see [http://www.impulsecontroldisorders.org/html/cravings.html Reference] | + | * [http://www.impulsecontroldisorders.org/images/8-Urges9proof.jpg Craving] - see [http://www.impulsecontroldisorders.org/html/cravings.html Reference] (CF.CRAVING) |
| − | <img src="http:// | + | NACC=Accumbens Nucleus,FEC.FT.ACC (see [[BrainCenterFEC_FT_BG|Basal Ganglia]]) |
| + | OMPFC=Orbitofrontal Cortex,NC.AL.OPFC (see [[BrainCenterNC_AL_OMPFC|Orbitomedial Prefrontal Cortex]]) | ||
| + | SNr=[[BrainRegionFEC_FT_SNR_MED|Substantia Nigra Pars Reticulata Medial,FEC.FT.SNR.MED]] | ||
| + | VPAL=Ventral Pallidum,FEC.FT.VP (see [[BrainCenterFEC_FT_BG|Basal Ganglia]]) | ||
| + | VTA=[[BrainRegionLMC_MM_VTA|Ventral Tegmental Area,LMC.MM.VTA]] | ||
| + | <img src="http://ahuman.org/svn/ahwiki/images/ext/03180da352394bdd7711e289118a3d96.jpg" alt=alt="unavailable" style="max-width: 100%;"> | ||
| − | * [http://www.expertsmind.com/CMSImages/250_Affective%20basal%20ganglia%20circuit.png Affective basal ganglia circuit] - see [http://www.expertsmind.com/topic/emotion/affective-basal-ganglia-circuit-93570.aspx Reference] | + | * [http://www.expertsmind.com/CMSImages/250_Affective%20basal%20ganglia%20circuit.png Affective basal ganglia circuit] - see [http://www.expertsmind.com/topic/emotion/affective-basal-ganglia-circuit-93570.aspx Reference] (CF.AFFECTIVE-BG) |
| − | <img src="http://ahuman.org/svn/ahwiki/images/ext/2b159b54189545739ee84da16d6bf0df.png" alt="unavailable" style="max-width: 100%;"> | + | NACC=Accumbens Nucleus,FEC.FT.ACC (see [[BrainCenterFEC_FT_BG|Basal Ganglia]]) |
| + | OMPFC=Orbitofrontal Cortex,NC.AL.OPFC (see [[BrainCenterNC_AL_OMPFC|Orbitomedial Prefrontal Cortex]]) | ||
| + | nBM=[[BrainRegionLMC_FT_NBM|Basal Nucleus of Meynert,LMC.FT.NBM]] | ||
| + | <img src="http://ahuman.org/svn/ahwiki/images/ext/2b159b54189545739ee84da16d6bf0df.png" alt=alt="unavailable" style="max-width: 100%;"> | ||
Latest revision as of 18:26, 28 April 2019
Nucleus Accumbens Shell
@@Home -> BiologicalLifeResearch -> BrainAreaFEC -> BrainRegionFEC_FT_ACC_SH
This page covers biological details of component Nucleus Accumbens Shell. Region is part of aHuman target integrated biological model.
- Top-down path to region: Forebrain Telencephalon -> Basal Ganglia (FEC.FT.BG) -> Striatum (FEC.FT.ST) -> Ventral Striatum (FEC.FT.VST) -> Accumbens Nucleus (FEC.FT.ACC) -> Nucleus Accumbens Shell (FEC.FT.ACC.SH) (see Mind Maps)
- Type: nucleus
- Quality: L0
- Brain area: Forebrain - Execution Control Area (FEC)
- Area circuit: Cognitive Motivational Salience (FECAF)
- Role: basal.ganglia.striatum
- Function: cognitive processing of motivational salience (wanting) as well as reward and reinforcement effects
(generated)
Components
(generated)
- no child items defined
Connectivity
(generated)
Inbound Region Connections:
| Source Area | Source Region | Source Name | Type | Role | Reference |
| FEC | FEC.FT.SNC.LT | Substantia Nigra Pars Compacta Lateral | modulatory-da | uncertain | Connectivity map of the habenula (SNc -> CPu, abstract) |
| FEC.FT.SNC.MED | Substantia Nigra Pars Compacta Medial | modulatory-da | uncertain | Connectivity map of the habenula (SNc -> CPu, abstract) | |
| LAC | LAC.FD.HT.VM | Ventromedial Hypothalamic Nucleus | excitatory-glu | uncertain | Bowels control brain: gut hormones and obesity (VMN -> NAc, abstract) |
| LMC | LMC.MM.VTA | Ventral Tegmental Area | modulatory-da | uncertain | Craving (VTA -> NACC, abstract) |
| LPC | LPC.HL.SOL | Solitary Nucleus | excitatory-glu | uncertain | Bowels control brain: gut hormones and obesity (NTS -> NAc, abstract) |
| LPC.HT.PRF.PB | Parabrachial Nucleus | excitatory-glu | uncertain | Bowels control brain: gut hormones and obesity (PBN -> NAc, abstract) | |
| NCP | NCP.NC.MPL.PSCG | Posterior Cingulate Cortex | excitatory-glu | uncertain | (unknown reference) |
| NDM | NDM.NC.AL.VACG | Ventral Anterior Cingulate Area | excitatory-glu | uncertain | Global visual system (FrontalCortex -> BGA, abstract) |
Outbound Region Connections:
| Target Area | Target Region | Target Name | Type | Role | Reference |
| FAM | FAM.FD.MHB | Medial Habenula | inhibitory-gaba | uncertain | Connectivity map of the habenula (NAc -> M, abstract) |
| FEC | FEC.FT.IPAC.LT | Lateral Interstitial Anterior Commissural Nucleus | inhibitory-gaba | uncertain | (unknown reference) |
| FEC.FT.VP.VM | Ventral Pallidum Ventromedial | inhibitory-gaba | uncertain | Craving (NACC -> VPAL, abstract) | |
| LAC | LAC.FD.HT.LTN | Lateral Hypothalamic Nucleus | inhibitory-gaba | uncertain | (unknown reference) |
| LMC | LMC.FT.NBM | Basal Nucleus of Meynert | inhibitory-gaba | uncertain | Affective basal ganglia circuit (NACC -> nBM, abstract) |
Thirdparty Circuits
(generated)
- Reward circuit of human brain - see Reference (CF.REWARD-CIRCUIT)
AM=Amygdala,FAM.FT.AM HC=Hippocampus,FMM.FT.HC (see Hippocampal Formation) NACC=Accumbens Nucleus,FEC.FT.ACC (see Basal Ganglia) PFC=Orbitofrontal Cortex,NC.AL.OPFC (see Orbitomedial Prefrontal Cortex) VPAL=Ventral Pallidum,FEC.FT.VP (see Basal Ganglia) VTA=Ventral Tegmental Area,LMC.MM.VTA
- Connectivity map of the habenula - see Reference (CF.HB-CONN)
CPu=Striatum,FEC.FT.ST (see Basal Ganglia) EP=Endopiriform Nucleus,FAM.FT.EPF Hippo=Hippocampus,FMM.FT.HC (see Hippocampal Formation) IPN=Interpeduncular Nucleus,FEC.HT.TG.IPD L=Lateral Habenula,FAM.FD.LHB (see Habenula) LH=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN M=Medial Habenula,FAM.FD.MHB NAc=Accumbens Nucleus,FEC.FT.ACC (see Basal Ganglia) PAG=Periaqueductal Gray Matter,LMC.MM.PAG Raphe=Raphe Nuclei of Medulla,LMC.HL.RP (see Medullary Reticular Formation) SNc=Substantia Nigra Pars Compacta,FEC.FT.SNC (see Basal Ganglia) Septum=Septal Nuclei,FAM.FT.SEP VTA=Ventral Tegmental Area,LMC.MM.VTA
NACC=Accumbens Nucleus,FEC.FT.ACC (see Basal Ganglia) OMPFC=Orbitofrontal Cortex,NC.AL.OPFC (see Orbitomedial Prefrontal Cortex) SNr=Substantia Nigra Pars Reticulata Medial,FEC.FT.SNR.MED VPAL=Ventral Pallidum,FEC.FT.VP (see Basal Ganglia) VTA=Ventral Tegmental Area,LMC.MM.VTA
- Affective basal ganglia circuit - see Reference (CF.AFFECTIVE-BG)
NACC=Accumbens Nucleus,FEC.FT.ACC (see Basal Ganglia) OMPFC=Orbitofrontal Cortex,NC.AL.OPFC (see Orbitomedial Prefrontal Cortex) nBM=Basal Nucleus of Meynert,LMC.FT.NBM
References
(generated)
