BrainRegionFEC FT SNR MED

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Substantia Nigra Pars Reticulata Medial

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This page covers biological details of component Substantia Nigra Pars Reticulata Medial. Region is part of aHuman target integrated biological model.

  • Top-down path to region: Forebrain Telencephalon -> Basal Ganglia (FEC.FT.BG) -> Substantia Nigra (FEC.FT.SN) -> Substantia Nigra Pars Reticulata (FEC.FT.SNR) -> Substantia Nigra Pars Reticulata Medial (FEC.FT.SNR.MED) (see Mind Maps)
  • Type: nucleus
  • Brain area: Forebrain - Execution Control Area
  • Role: basal.ganglia.nigrareticulata
  • Function: Motivational loop

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Components

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  • no child items defined

Connectivity

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FEC.FT.SNR.MED.dot.png

Inbound Region Connections:

Source Area Source Region Source Name Type Reference
FEC FEC.FD.STN.DL Subthalamic Nucleus Dorsolateral excitatory-glu (unknown reference)
FEC.FT.ACC.CORE Nucleus Accumbens Core inhibitory-gaba Craving (NACC -> SNr, abstract)
FEC.FT.CN.TL Caudate Nucleus Tail inhibitory-gaba Saccades and smooth movements (CN -> SN, abstract)
FEC.FT.GPE.RM Globus Pallidus External Rostromedial inhibitory-gaba Prefrontal Cortex (PFC) in motor behavior (GP -> SN, abstract)
FEC.FT.PU.VT Ventral Putamen inhibitory-gaba (unknown reference)
FEC.FT.VP.DL Ventral Pallidum Dorsolateral inhibitory-gaba Craving (VPAL -> SNr, abstract)
NDM NDM.NC.AL.FPC Lateral Frontopolar Cortex excitatory-glu Global visual system (FrontalCortex -> BGA, abstract)

Outbound Region Connections:

Target Area Target Region Target Name Type Reference
FEC FEC.FT.SNC.MED Substantia Nigra Pars Compacta Medial inhibitory-gaba (unknown reference)
FEC.HT.TG.IPD Interpeduncular Nucleus inhibitory-gaba (unknown reference)
NMA NMA.FD.TH.MDL Lateral Mediodorsal Nucleus of Thalamus inhibitory-gaba Saccadic Vision (BG -> Thalamus, abstract)

Thirdparty Circuits

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map: BG=Basal Ganglia,FEC.FT.BG, CN=Caudate Nucleus,FEC.FT.CN (Caudate Nucleus Head (FEC.FT.CN.HD), Caudate Nucleus Body (FEC.FT.CN.BD), Caudate Nucleus Tail (FEC.FT.CN.TL)), CR=Cerebellum,LLC.HT.CR (Cerebellar Flocconodular Lobe (LRC.HT.CR.FN), Cerebellar Lateral Lobe (LLC.HT.CR.CC), Cerebellar Paravermis (LLC.HT.CR.PV), Cerebellar Vermis (LRC.HT.CR.VM)), FrontalCortex=Anterior Lobe,NC.LOBE.ANT (Rostral Mid-Dorsolateral Prefrontal Cortex (NDM.NC.AL.DLPFCR), Lateral Mid-Dorsolateral Prefrontal Cortex (NDM.NC.AL.DLPFCL), Inferior Prefrontal Gyrus (NDM.NC.AL.IPG), Broca's Area Pars Opercularis (NPE.NC.BRA.PO), Broca's Area Pars Triangularis (NPE.NC.BRA.PT), Lateral Frontopolar Cortex (NDM.NC.AL.FPC), Most Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCR), Sulcal Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCS), Medial Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCM), Lateral Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCL), Dorsomedial Prefrontal Cortex (NDM.NC.AL.DMPFC), Ventromedial Prefrontal Cortex (NDM.NC.AL.VMPFC), Ventral Anterior Cingulate Area (NDM.NC.AL.VACG), Dorsal Anterior Cingulate Area (NDM.NC.AL.DACG), Subgenual Cingulate Cortex (NCP.NC.AL.SGCG), Ventral Medial Cingulate Area (NDM.NC.AL.VMCG), Dorsal Medial Cingulate Area (NDM.NC.AL.DMCG), Pregenual Cingulate Cortex (NDM.NC.AL.PGCG), Motor Cortex (NMA.NC.MC), Caudal Frontal Eye Field (NPE.NC.PMC.CFEF), Anterior Frontal Eye Field (NPE.NC.PMC.AFEF), Dorsal Caudal Premotor Cortex (NMA.NC.PMC.F2), Dorsal Rostral Premotor Cortex (NMA.NC.PMC.F7), Ventral Caudal Premotor Cortex (NMA.NC.PMC.F4), Ventral Rostral Premotor Cortex (NMA.NC.PMC.F5), Supplementary Eye Field (NPE.NC.SMC.SEF), Pre-Supplementary Motor Area (NMA.NC.SMC.F6), Supplementary Motor Area (NMA.NC.SMC.F3)), GPe=Globus Pallidus External,FEC.FT.GPE (Globus Pallidus External Lateral (FEC.FT.GPE.LT), Globus Pallidus External Medial (FEC.FT.GPE.MED), Globus Pallidus External Dorsal (FEC.FT.GPE.DS), Globus Pallidus External Rostromedial (FEC.FT.GPE.RM), Globus Pallidus External Dorsolateral (FEC.FT.GPE.DL)), LGN=Lateral Geniculate Nucleus,NSA.FD.LGN, LIP=Lateral Intraparietal Sulcus,NPE.NC.IPS.LIP, RF=Pontine Reticular Formation,HT.RF, Retina=Retinal Nucleus,LPC.FD.RT, SCi=Superior Colliculus,MM.SC (Superficial Superior Colliculus (LRC.MM.SC.SUP), Intermediate Superior Colliculus (LRC.MM.SC.INT), Deep Superior Colliculus (LRC.MM.SC.DEEP)), SCs=Superior Colliculus,MM.SC (Superficial Superior Colliculus (LRC.MM.SC.SUP), Intermediate Superior Colliculus (LRC.MM.SC.INT), Deep Superior Colliculus (LRC.MM.SC.DEEP)), SNpr=Substantia Nigra Pars Reticulata Dorsolateral,FEC.FT.SNR.DL, STN=Subthalamic Nucleus,FEC.FD.STN (Subthalamic Nucleus Caudal (FEC.FD.STN.CD), Subthalamic Nucleus Internal Caudal (FEC.FD.STN.ICD), Subthalamic Nucleus Dorsolateral (FEC.FD.STN.DL), Subthalamic Nucleus Lateral (FEC.FD.STN.LT), Subthalamic Nucleus Medial (FEC.FD.STN.MED)), Thalamus=Thalamus,FD.TH (Lateral Geniculate Nucleus (NSA.FD.LGN), Medial Geniculate Body (NSA.FD.TH.MGB), Ventral Posteroinferior Nucleus (NCP.FD.TH.VPI), Ventral Posterolateral Nucleus (NCP.FD.TH.VPL), Ventral Posteromedial Nucleus (NCP.FD.TH.VPM), Inferior Pulvinar (NSA.FD.TH.IPV), Lateral Pulvinar (NSA.FD.TH.LPV), Medial Pulvinar (NPE.FD.TH.MPV), Oral Pulvinar (NPE.FD.TH.OPV), Limitans Nucleus of Thalamus (NCP.FD.TH.LI), Suprageniculate Nucleus of Thalamus (NSA.FD.TH.SG), Submedial Nucleus of Thalamus (NDM.FD.TH.SM), Ventral Anterior Nucleus (NMA.FD.TH.VA), Ventral Lateral Nucleus (NMA.FD.TH.VL), Lateral Dorsal Nucleus of Thalamus (FMM.FD.TH.LD), Lateral Posterior Nucleus of Thalamus (NPE.FD.TH.LP), Medial Mediodorsal Nucleus of Thalamus (NDM.FD.TH.MDM), Central Mediodorsal Nucleus of Thalamus (NCP.FD.TH.MDC), Lateral Mediodorsal Nucleus of Thalamus (NMA.FD.TH.MDL), Anteromedial Nucleus (NCP.FD.TH.AM), Anteroventral Nucleus (FMM.FD.TH.AV), Anterodorsal Nucleus (FMM.FD.TH.AD), Rostral Intralaminar Nuclear Group of Thalamus (NCP.FD.TH.RIL), Centromedian Nucleus of Thalamus (FEC.FD.TH.CM), Parafascicular Nucleus of Thalamus (FEC.FD.TH.PF), Paratenial Nucleus of Thalamus (FAM.FD.TH.PT), Paraventricular Nucleus of Thalamus (NDM.FD.TH.PV), Reuniens Nucleus of Thalamus (FMM.FD.TH.RE), Rhomboidal Nucleus of Thalamus (FMM.FD.TH.RH), Subfascicular Nucleus of Thalamus (LLC.FD.TH.SF)), VisualCortex=Occipital Lobe,NC.LOBE.OCC unavailable

map: NACC=Accumbens Nucleus,FEC.FT.ACC (Nucleus Accumbens Core (FEC.FT.ACC.CORE), Nucleus Accumbens Shell (FEC.FT.ACC.SH)), OMPFC=Orbitofrontal Cortex,NC.AL.OPFC (Lateral Frontopolar Cortex (NDM.NC.AL.FPC), Most Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCR), Sulcal Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCS), Medial Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCM), Lateral Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCL)), SNr=Substantia Nigra Pars Reticulata Medial,FEC.FT.SNR.MED, VPAL=Ventral Pallidum,FEC.FT.VP (Ventral Pallidum Dorsolateral (FEC.FT.VP.DL), Ventral Pallidum Ventromedial (FEC.FT.VP.VM)), VTA=Ventral Tegmental Area,LMC.MM.VTA unavailable


References

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