BrainRegionFAM FT AM LAVM

Ventromedial Amygdaloid Nucleus

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This page covers biological details of component Ventromedial Amygdaloid Nucleus. Region is part of aHuman target integrated biological model.

• Top-down path to region: Forebrain Telencephalon -> Extended Amygdala (FAM.FT.EXTAM) -> Amygdala (FAM.FT.AM) -> Basolateral Nuclear Complex (FAM.FT.AM.BL) -> Lateral Amygdaloid Nucleus (FAM.FT.AM.LA) -> Ventromedial Amygdaloid Nucleus (FAM.FT.AM.LAVM) (see Mind Maps)
• Type: nucleus
• Quality: L0
• Brain area: Forebrain - Affective Motivations Area
• Role: processor.affective
• Function: conditional and unconditional convergence to affect polymodal memory formation
• Notes to function:
  • LA3
  • projects to ET

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Components

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• no child items defined

Connectivity

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Inbound Region Connections:

Source Area	Source Region	Source Name	Type	Reference
FAM	FAM.FT.AM.LADL	Dorsolateral Amygdaloid Nucleus	excitatory-glu	(unknown reference)
FMM	FMM.FT.HC.CA1D	Distal CA1 of Hippocampus	excitatory-glu	Fear regulation (Hippocampus -> LA, abstract)
	FMM.NC.PH.LEC	Lateral Entorhinal Cortex	excitatory-glu	Simplified model of hippocampal formation anatomy (EC -> Amyg, abstract)
NSA	NSA.NC.STG.A3	Wernicke's area A3	excitatory-glu	Amygdala and its network (STC -> LA, abstract)

Outbound Region Connections:

Target Area	Target Region	Target Name	Type	Reference
FAM	FAM.FT.AM.AB	Accessory Basal Amygdaloid Nucleus	excitatory-glu	Summary of the main extra-amygdaloid and intra-amygdaloid connections in the rat (L -> AB, abstract)
	FAM.FT.AM.MPV	Medial Posterior Ventral Amygdaloid Nucleus	excitatory-glu	Summary of the main extra-amygdaloid and intra-amygdaloid connections in the rat (L -> M, abstract)
LPC	LPC.MM.CIC	Central Nucleus of Inferior Colliculus	excitatory-glu	Visual-Auditory Interactions in Tectum (AM -> IC, abstract)
NDM	NDM.FD.TH.PV	Paraventricular Nucleus of Thalamus	excitatory-glu	Oculomotor decision-making (AMYG -> Thalamus, abstract)

Thirdparty Circuits

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• Principal Connections of Hippocampus - see Reference (CT.CINGULUM-CONNECTIONS)

AM=Amygdala,FAM.FT.AM
AN=Anterior Nucleus of Thalamus,FD.TH.AN (see Cognitive Thalamus)
DG=Dentate Gyrus,FMM.FT.HC.DG
DorsalCingulate=Dorsal Anterior Cingulate Area,NDM.NC.AL.DACG
EC=Entorhinal Cortex,FMM.NC.PH.ET (see Rhinal Cortex)
HC=Subiculum,FMM.FT.HF.SUB (see Hippocampal Formation)
MB=Medial Mammillary Nucleus,FMM.FD.MB.MMB
PosteriorCingulate=Posterior Cingulate Cortex,NCP.NC.MPL.PSCG
SEP=Septal Nuclei,FAM.FT.SEP
SUB=Subiculum,FMM.FT.HF.SUB (see Hippocampal Formation)
VentralCingulate=Ventral Anterior Cingulate Area,NDM.NC.AL.VACG

• Visual-Auditory Interactions in Tectum - see Reference (CP.VISUAL-AUDITORY-INTERACTIONS)

AC=Primary Auditory Cortex,NSA.NC.TTG.A1
AM=Amygdala,FAM.FT.AM
CN=Cochlear Nucleus,LPC.HL.COCH (see Myelencephalic Sensory Nuclei)
IC=Inferior Colliculus,ABA.MM.IC (see Reflexes Nuclei of Midbrain Mesencephalon)
MGB=Medial Geniculate Body,NSA.FD.TH.MGB
OC=Superior Olivary Complex,LPC.MM.SOC
PM=Premotor Cortex,NC.PMC
SC=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon)

• Oculomotor decision-making - see Reference (CP.OCULOMOTOR-DECISION-MAKING)

AMYG=Amygdala,FAM.FT.AM
CGa=Anterior Cingulate Cortex,NC.AL.ACG (see Anterior Cingulate Area)
CGp=Posterior Cingulate Cortex,NCP.NC.MPL.PSCG
Caudate=Caudate Nucleus,FEC.FT.CN (see Basal Ganglia)
FEF=Frontal Eye Field,NMA.NC.PMC.FEF (see Premotor Cortex)
LIP=Lateral Intraparietal Sulcus,NPE.NC.IPS.LIP
NAC=Accumbens Nucleus,FEC.FT.ACC (see Basal Ganglia)
OFC=Orbitofrontal Cortex,NC.AL.OPFC (see Orbitomedial Prefrontal Cortex)
PFC=Mid-Dorsolateral Prefrontal Cortex,NDM.NC.AL.DLPFC (see Lateral Prefrontal Cortex)
SC=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon)
SEF=Supplementary Eye Field,NPE.NC.SMC.SEF
SNc=Substantia Nigra Pars Compacta Lateral,FEC.FT.SNC.LT
SNr=Substantia Nigra Pars Reticulata Dorsolateral,FEC.FT.SNR.DL
Thalamus=Thalamus,FD.TH
VTA=Ventral Tegmental Area,LMC.MM.VTA

• Summary of the main extra-amygdaloid and intra-amygdaloid connections in the rat - see Reference (CF.AM-SUMMARY)

AB=Accessory Basal Amygdaloid Nucleus,FAM.FT.AM.AB
B=Basal Amygdaloid Nucleus,FAM.FT.AM.B (see Amygdala)
CE=Central Amygdala,FAM.FT.AM.CEA (see Amygdala)
L=Lateral Amygdaloid Nucleus,FAM.FT.AM.LA (see Amygdala)
M=Medial Amygdala,FAM.FT.AM.M (see Amygdala)

• Neuronal projections in the hippocampus - see Reference (CF.AM-HC)

BLA=Basolateral Nuclear Complex,FAM.FT.AM.BL (see Amygdala)
CA1=Ventrolateral Cornu Ammonis of Hippocampus,FMM.FT.HC.CA1 (see Hippocampal Formation)
CA3=Dorsomedial Cornu Ammonis of Hippocampus,FMM.FT.HC.CA3 (see Hippocampal Formation)
DG=Dentate Gyrus,FMM.FT.HC.DG
ET=Entorhinal Cortex,FMM.NC.PH.ET (see Rhinal Cortex)

References

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• http://highered.mcgraw-hill.com/sites/dl/free/0071402357/156721/figure350_1.html
• http://f1000research.com/articles/2-20/v1
• http://www.springerimages.com/Images/LifeSciences/1-10.1007_s00359-004-0565-9-0
• http://journal.frontiersin.org/article/10.3389/fphar.2014.00068/full
• http://journal.frontiersin.org/Journal/10.3389/fpsyt.2013.00061/full