Difference between revisions of "BrainRegionFAM FT AM LAVM"
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<pre style="color: green">Ventromedial Amygdaloid Nucleus</pre> | <pre style="color: green">Ventromedial Amygdaloid Nucleus</pre> | ||
@@[[Home]] -> [[BiologicalLifeResearch]] -> [[BrainAreaFAM]] -> [[BrainRegionFAM_FT_AM_LAVM]] | @@[[Home]] -> [[BiologicalLifeResearch]] -> [[BrainAreaFAM]] -> [[BrainRegionFAM_FT_AM_LAVM]] | ||
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Region is part of aHuman target integrated biological model. | Region is part of aHuman target integrated biological model. | ||
− | * '''Top-down path to region''': Forebrain Telencephalon -> Extended Amygdala (FAM.FT.EXTAM) -> [[BrainCenterFAM_FT_AM|Amygdala]] (FAM.FT.AM) -> Basolateral Nuclear Complex (FAM.FT.AM.BL) -> Lateral Amygdaloid Nucleus (FAM.FT.AM.LA) -> Ventromedial Amygdaloid Nucleus (FAM.FT.AM.LAVM) (see [[OverallMindMaps|Mind Maps]]) | + | * '''Top-down path to region''': Forebrain Telencephalon -> Extended Amygdala (FAM.FT.EXTAM) -> [[BrainCenterFAM_FT_AM|Amygdala]] (FAM.FT.AM) -> Basolateral Nuclear Complex (FAM.FT.AM.BL) -> Lateral Amygdaloid Nucleus (FAM.FT.AM.LA) -> [[BrainRegionFAM_FT_AM_LAVM|Ventromedial Amygdaloid Nucleus]] (FAM.FT.AM.LAVM) (see [[OverallMindMaps|Mind Maps]]) |
* '''Type''': nucleus | * '''Type''': nucleus | ||
− | * '''Brain area''': [[BrainAreaFAM|Forebrain - Affective Motivations Area]] | + | * '''Quality''': L0 |
− | * '''Role''': | + | * '''Brain area''': [[BrainAreaFAM|Forebrain - Affective Motivations Area]] (FAM) |
+ | * '''Area circuit''': Fast Unconditional Sensory Data and Association Memory (FAMXUS) | ||
+ | * '''Role''': processor.affective | ||
* '''Function''': conditional and unconditional convergence to affect polymodal memory formation | * '''Function''': conditional and unconditional convergence to affect polymodal memory formation | ||
− | * '''Notes to function''': LA3 | + | * '''Notes to function''': |
+ | ** LA3 | ||
+ | ** projects to ET | ||
(generated) | (generated) | ||
= Components = | = Components = | ||
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{| class=wikitable width=80% | {| class=wikitable width=80% | ||
− | | '''Source Area''' || '''Source Region''' || '''Source Name''' || '''Type''' || '''Reference''' | + | | '''Source Area''' || '''Source Region''' || '''Source Name''' || '''Type''' || '''Role''' || '''Reference''' |
|- | |- | ||
− | | [[BrainAreaFAM|FAM]] || [[BrainRegionFAM_FT_AM_LADL|FAM.FT.AM.LADL]] || Dorsolateral Amygdaloid Nucleus || excitatory-glu || (unknown reference) | + | | [[BrainAreaFAM|FAM]] || [[BrainRegionFAM_FT_AM_LADL|FAM.FT.AM.LADL]] || Dorsolateral Amygdaloid Nucleus || excitatory-glu || uncertain ||(unknown reference) |
|- | |- | ||
− | | [[BrainAreaNSA|NSA]] || [[BrainRegionNSA_NC_STG_A3|NSA.NC.STG.A3]] || Wernicke's area A3 || excitatory-glu || [http://www.surgicalneurologyint.com/article.asp?issn=2152-7806;year=2012;volume=3;issue=2;spage=40;epage=46;aulast=Langevin Amygdala and its network (STC -> LA, abstract)] | + | | [[BrainAreaFMM|FMM]] || [[BrainRegionFMM_FT_HC_CA1D|FMM.FT.HC.CA1D]] || Distal CA1 of Hippocampus || excitatory-glu || uncertain ||[https://brmlab.cz/project/brain_hacking/tdcs/pfc Fear regulation (Hippocampus -> LA, abstract)] |
+ | |- | ||
+ | | || [[BrainRegionFMM_NC_PH_LEC|FMM.NC.PH.LEC]] || Lateral Entorhinal Cortex || excitatory-glu || uncertain ||[http://www.sciencedirect.com/science/article/pii/S030100820900183X Simplified model of hippocampal formation anatomy (EC -> Amyg, abstract)] | ||
+ | |- | ||
+ | | [[BrainAreaNSA|NSA]] || [[BrainRegionNSA_NC_STG_A3|NSA.NC.STG.A3]] || Wernicke's area A3 || excitatory-glu || uncertain ||[http://www.surgicalneurologyint.com/article.asp?issn=2152-7806;year=2012;volume=3;issue=2;spage=40;epage=46;aulast=Langevin Amygdala and its network (STC -> LA, abstract)] | ||
|} | |} | ||
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{| class=wikitable width=80% | {| class=wikitable width=80% | ||
− | | '''Target Area''' || '''Target Region''' || '''Target Name''' || '''Type''' || '''Reference''' | + | | '''Target Area''' || '''Target Region''' || '''Target Name''' || '''Type''' || '''Role''' || '''Reference''' |
|- | |- | ||
− | | [[BrainAreaFAM|FAM]] || [[BrainRegionFAM_FT_AM_AB|FAM.FT.AM.AB]] || Accessory Basal Amygdaloid Nucleus || excitatory-glu || [http:// | + | | [[BrainAreaFAM|FAM]] || [[BrainRegionFAM_FT_AM_AB|FAM.FT.AM.AB]] || Accessory Basal Amygdaloid Nucleus || excitatory-glu || uncertain || [http://journal.frontiersin.org/article/10.3389/fphar.2014.00068/full Summary of the main extra-amygdaloid and intra-amygdaloid connections in the rat (L -> AB, abstract)] |
|- | |- | ||
− | | || [[BrainRegionFAM_FT_AM_MPV|FAM.FT.AM.MPV]] || Medial | + | | || [[BrainRegionFAM_FT_AM_MPV|FAM.FT.AM.MPV]] || Medial Posterior Ventral Amygdaloid Nucleus || excitatory-glu || uncertain || [http://journal.frontiersin.org/article/10.3389/fphar.2014.00068/full Summary of the main extra-amygdaloid and intra-amygdaloid connections in the rat (L -> M, abstract)] |
|- | |- | ||
− | | [[BrainAreaLPC|LPC]] || [[ | + | | [[BrainAreaLPC|LPC]] || [[BrainRegionLPC_MM_CIC|LPC.MM.CIC]] || Central Nucleus of Inferior Colliculus || excitatory-glu || uncertain || [http://f1000research.com/articles/2-20/v1 Visual-Auditory Interactions in Tectum (AM -> IC, abstract)] |
|- | |- | ||
− | | | + | | [[BrainAreaNDM|NDM]] || [[BrainRegionNDM_FD_TH_PV|NDM.FD.TH.PV]] || Paraventricular Nucleus of Thalamus || excitatory-glu || uncertain || [http://www.springerimages.com/Images/LifeSciences/1-10.1007_s00359-004-0565-9-0 Oculomotor decision-making (AMYG -> Thalamus, abstract)] |
|} | |} | ||
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(generated) | (generated) | ||
− | * | + | * [http://highered.mcgraw-hill.com/sites/dl/free/0071402357/156721/figure350_1.gif Principal Connections of Hippocampus] - see [http://highered.mcgraw-hill.com/sites/dl/free/0071402357/156721/figure350_1.html Reference] (CT.CINGULUM-CONNECTIONS) |
+ | |||
+ | AM=[[BrainCenterFAM_FT_AM|Amygdala,FAM.FT.AM]] | ||
+ | AN=Anterior Nucleus of Thalamus,FD.TH.AN (see [[BrainCenterFD_TH_CR|Cognitive Thalamus]]) | ||
+ | DG=[[BrainRegionFMM_FT_HC_DG|Dentate Gyrus,FMM.FT.HC.DG]] | ||
+ | DorsalCingulate=[[BrainRegionNDM_NC_AL_DACG|Dorsal Anterior Cingulate Area,NDM.NC.AL.DACG]] | ||
+ | EC=Entorhinal Cortex,FMM.NC.PH.ET (see [[BrainCenterNC_PHA_RH|Rhinal Cortex]]) | ||
+ | HC=Subiculum,FMM.FT.HF.SUB (see [[BrainCenterFMM_FT_HF|Hippocampal Formation]]) | ||
+ | MB=[[BrainRegionFMM_FD_MB_MMB|Medial Mammillary Nucleus,FMM.FD.MB.MMB]] | ||
+ | PosteriorCingulate=[[BrainRegionNCP_NC_MPL_PSCG|Posterior Cingulate Cortex,NCP.NC.MPL.PSCG]] | ||
+ | SEP=[[BrainCenterFAM_FT_SEP|Septal Nuclei,FAM.FT.SEP]] | ||
+ | SUB=Subiculum,FMM.FT.HF.SUB (see [[BrainCenterFMM_FT_HF|Hippocampal Formation]]) | ||
+ | VentralCingulate=[[BrainRegionNDM_NC_AL_VACG|Ventral Anterior Cingulate Area,NDM.NC.AL.VACG]] | ||
+ | <img src="http://ahuman.org/svn/ahwiki/images/ext/b2f112f73e5b1419bea90cefc9f4b29a.gif" alt=alt="unavailable" style="max-width: 100%;"> | ||
+ | |||
+ | * [http://cdn.f1000r.com.s3.amazonaws.com/manuscripts/1181/d6e9eca8-bb85-4382-8286-723b00f8b36f_figure7.gif Visual-Auditory Interactions in Tectum] - see [http://f1000research.com/articles/2-20/v1 Reference] (CP.VISUAL-AUDITORY-INTERACTIONS) | ||
+ | |||
+ | AC=[[BrainRegionNSA_NC_TTG_A1|Primary Auditory Cortex,NSA.NC.TTG.A1]] | ||
+ | AM=[[BrainCenterFAM_FT_AM|Amygdala,FAM.FT.AM]] | ||
+ | CN=Cochlear Nucleus,LPC.HL.COCH (see [[BrainCenterHL_SN|Myelencephalic Sensory Nuclei]]) | ||
+ | IC=Inferior Colliculus,ABA.MM.IC (see [[BrainCenterMM_REF|Reflexes Nuclei of Midbrain Mesencephalon]]) | ||
+ | MGB=[[BrainRegionNSA_FD_TH_MGB|Medial Geniculate Body,NSA.FD.TH.MGB]] | ||
+ | OC=[[BrainRegionLPC_MM_SOC|Superior Olivary Complex,LPC.MM.SOC]] | ||
+ | PM=[[BrainCenterNC_PMC|Premotor Cortex,NC.PMC]] | ||
+ | SC=Superior Colliculus,MM.SC (see [[BrainCenterMM_REF|Reflexes Nuclei of Midbrain Mesencephalon]]) | ||
+ | <img src="http://ahuman.org/svn/ahwiki/images/ext/116326cb2eb32664b3d13f928647d94a.gif" alt=alt="unavailable" style="max-width: 100%;" height=400 width=400> | ||
+ | |||
+ | * [http://img.springerimages.com/Images/Springer/PUB=Springer-Verlag-Berlin-Heidelberg/JOU=00359/VOL=2005.191/ISU=3/ART=2004_565/MediaObjects/WATER_s00359-004-0565-9fhc1.jpg Oculomotor decision-making] - see [http://www.springerimages.com/Images/LifeSciences/1-10.1007_s00359-004-0565-9-0 Reference] (CP.OCULOMOTOR-DECISION-MAKING) | ||
+ | |||
+ | AMYG=[[BrainCenterFAM_FT_AM|Amygdala,FAM.FT.AM]] | ||
+ | CGa=Anterior Cingulate Cortex,NC.AL.ACG (see [[BrainCenterNC_ACG|Anterior Cingulate Area]]) | ||
+ | CGp=[[BrainRegionNCP_NC_MPL_PSCG|Posterior Cingulate Cortex,NCP.NC.MPL.PSCG]] | ||
+ | Caudate=Caudate Nucleus,FEC.FT.CN (see [[BrainCenterFEC_FT_BG|Basal Ganglia]]) | ||
+ | FEF=Frontal Eye Field,NMA.NC.PMC.FEF (see [[BrainCenterNC_PMC|Premotor Cortex]]) | ||
+ | LIP=[[BrainRegionNPE_NC_IPS_LIP|Lateral Intraparietal Sulcus,NPE.NC.IPS.LIP]] | ||
+ | NAC=Accumbens Nucleus,FEC.FT.ACC (see [[BrainCenterFEC_FT_BG|Basal Ganglia]]) | ||
+ | OFC=Orbitofrontal Cortex,NC.AL.OPFC (see [[BrainCenterNC_AL_OMPFC|Orbitomedial Prefrontal Cortex]]) | ||
+ | PFC=Mid-Dorsolateral Prefrontal Cortex,NDM.NC.AL.DLPFC (see [[BrainCenterNC_AL_LPFC|Lateral Prefrontal Cortex]]) | ||
+ | SC=Superior Colliculus,MM.SC (see [[BrainCenterMM_REF|Reflexes Nuclei of Midbrain Mesencephalon]]) | ||
+ | SEF=[[BrainRegionNPE_NC_SMC_SEF|Supplementary Eye Field,NPE.NC.SMC.SEF]] | ||
+ | SNc=[[BrainRegionFEC_FT_SNC_LT|Substantia Nigra Pars Compacta Lateral,FEC.FT.SNC.LT]] | ||
+ | SNr=[[BrainRegionFEC_FT_SNR_DL|Substantia Nigra Pars Reticulata Dorsolateral,FEC.FT.SNR.DL]] | ||
+ | Thalamus=Thalamus,FD.TH | ||
+ | VTA=[[BrainRegionLMC_MM_VTA|Ventral Tegmental Area,LMC.MM.VTA]] | ||
+ | <img src="http://ahuman.org/svn/ahwiki/images/ext/1d4f1e638e95cbcc831ce811b7c2518a.jpg" alt=alt="unavailable" style="max-width: 100%;"> | ||
+ | |||
+ | * [http://www.frontiersin.org/files/Articles/88542/fphar-05-00068-HTML/image_m/fphar-05-00068-g002.jpg Summary of the main extra-amygdaloid and intra-amygdaloid connections in the rat] - see [http://journal.frontiersin.org/article/10.3389/fphar.2014.00068/full Reference] (CF.AM-SUMMARY) | ||
+ | |||
+ | AB=[[BrainRegionFAM_FT_AM_AB|Accessory Basal Amygdaloid Nucleus,FAM.FT.AM.AB]] | ||
+ | B=Basal Amygdaloid Nucleus,FAM.FT.AM.B (see [[BrainCenterFAM_FT_AM|Amygdala]]) | ||
+ | CE=Central Amygdala,FAM.FT.AM.CEA (see [[BrainCenterFAM_FT_AM|Amygdala]]) | ||
+ | L=Lateral Amygdaloid Nucleus,FAM.FT.AM.LA (see [[BrainCenterFAM_FT_AM|Amygdala]]) | ||
+ | M=Medial Amygdala,FAM.FT.AM.M (see [[BrainCenterFAM_FT_AM|Amygdala]]) | ||
+ | <img src="http://ahuman.org/svn/ahwiki/images/ext/12d92703331843e844fd261118d3b3b7.jpg" alt=alt="unavailable" style="max-width: 100%;"> | ||
+ | |||
+ | * [http://www.frontiersin.org/files/Articles/46459/fpsyt-04-00061-HTML/image_m/fpsyt-04-00061-g002.jpg Neuronal projections in the hippocampus] - see [http://journal.frontiersin.org/Journal/10.3389/fpsyt.2013.00061/full Reference] (CF.AM-HC) | ||
+ | |||
+ | BLA=Basolateral Nuclear Complex,FAM.FT.AM.BL (see [[BrainCenterFAM_FT_AM|Amygdala]]) | ||
+ | CA1=Ventrolateral Cornu Ammonis of Hippocampus,FMM.FT.HC.CA1 (see [[BrainCenterFMM_FT_HF|Hippocampal Formation]]) | ||
+ | CA3=Dorsomedial Cornu Ammonis of Hippocampus,FMM.FT.HC.CA3 (see [[BrainCenterFMM_FT_HF|Hippocampal Formation]]) | ||
+ | DG=[[BrainRegionFMM_FT_HC_DG|Dentate Gyrus,FMM.FT.HC.DG]] | ||
+ | ET=Entorhinal Cortex,FMM.NC.PH.ET (see [[BrainCenterNC_PHA_RH|Rhinal Cortex]]) | ||
+ | <img src="http://ahuman.org/svn/ahwiki/images/ext/6db5356f9304330012fda936b30e6d95.jpg" alt=alt="unavailable" style="max-width: 100%;"> | ||
+ | |||
= References = | = References = | ||
(generated) | (generated) | ||
− | * | + | * http://highered.mcgraw-hill.com/sites/dl/free/0071402357/156721/figure350_1.html |
+ | * http://f1000research.com/articles/2-20/v1 | ||
+ | * http://www.springerimages.com/Images/LifeSciences/1-10.1007_s00359-004-0565-9-0 | ||
+ | * http://journal.frontiersin.org/article/10.3389/fphar.2014.00068/full | ||
+ | * http://journal.frontiersin.org/Journal/10.3389/fpsyt.2013.00061/full |
Latest revision as of 18:25, 28 April 2019
Ventromedial Amygdaloid Nucleus
@@Home -> BiologicalLifeResearch -> BrainAreaFAM -> BrainRegionFAM_FT_AM_LAVM
This page covers biological details of component Ventromedial Amygdaloid Nucleus. Region is part of aHuman target integrated biological model.
- Top-down path to region: Forebrain Telencephalon -> Extended Amygdala (FAM.FT.EXTAM) -> Amygdala (FAM.FT.AM) -> Basolateral Nuclear Complex (FAM.FT.AM.BL) -> Lateral Amygdaloid Nucleus (FAM.FT.AM.LA) -> Ventromedial Amygdaloid Nucleus (FAM.FT.AM.LAVM) (see Mind Maps)
- Type: nucleus
- Quality: L0
- Brain area: Forebrain - Affective Motivations Area (FAM)
- Area circuit: Fast Unconditional Sensory Data and Association Memory (FAMXUS)
- Role: processor.affective
- Function: conditional and unconditional convergence to affect polymodal memory formation
- Notes to function:
- LA3
- projects to ET
(generated)
Components
(generated)
- no child items defined
Connectivity
(generated)
Inbound Region Connections:
Source Area | Source Region | Source Name | Type | Role | Reference |
FAM | FAM.FT.AM.LADL | Dorsolateral Amygdaloid Nucleus | excitatory-glu | uncertain | (unknown reference) |
FMM | FMM.FT.HC.CA1D | Distal CA1 of Hippocampus | excitatory-glu | uncertain | Fear regulation (Hippocampus -> LA, abstract) |
FMM.NC.PH.LEC | Lateral Entorhinal Cortex | excitatory-glu | uncertain | Simplified model of hippocampal formation anatomy (EC -> Amyg, abstract) | |
NSA | NSA.NC.STG.A3 | Wernicke's area A3 | excitatory-glu | uncertain | Amygdala and its network (STC -> LA, abstract) |
Outbound Region Connections:
Target Area | Target Region | Target Name | Type | Role | Reference |
FAM | FAM.FT.AM.AB | Accessory Basal Amygdaloid Nucleus | excitatory-glu | uncertain | Summary of the main extra-amygdaloid and intra-amygdaloid connections in the rat (L -> AB, abstract) |
FAM.FT.AM.MPV | Medial Posterior Ventral Amygdaloid Nucleus | excitatory-glu | uncertain | Summary of the main extra-amygdaloid and intra-amygdaloid connections in the rat (L -> M, abstract) | |
LPC | LPC.MM.CIC | Central Nucleus of Inferior Colliculus | excitatory-glu | uncertain | Visual-Auditory Interactions in Tectum (AM -> IC, abstract) |
NDM | NDM.FD.TH.PV | Paraventricular Nucleus of Thalamus | excitatory-glu | uncertain | Oculomotor decision-making (AMYG -> Thalamus, abstract) |
Thirdparty Circuits
(generated)
- Principal Connections of Hippocampus - see Reference (CT.CINGULUM-CONNECTIONS)
AM=Amygdala,FAM.FT.AM AN=Anterior Nucleus of Thalamus,FD.TH.AN (see Cognitive Thalamus) DG=Dentate Gyrus,FMM.FT.HC.DG DorsalCingulate=Dorsal Anterior Cingulate Area,NDM.NC.AL.DACG EC=Entorhinal Cortex,FMM.NC.PH.ET (see Rhinal Cortex) HC=Subiculum,FMM.FT.HF.SUB (see Hippocampal Formation) MB=Medial Mammillary Nucleus,FMM.FD.MB.MMB PosteriorCingulate=Posterior Cingulate Cortex,NCP.NC.MPL.PSCG SEP=Septal Nuclei,FAM.FT.SEP SUB=Subiculum,FMM.FT.HF.SUB (see Hippocampal Formation) VentralCingulate=Ventral Anterior Cingulate Area,NDM.NC.AL.VACG
- Visual-Auditory Interactions in Tectum - see Reference (CP.VISUAL-AUDITORY-INTERACTIONS)
AC=Primary Auditory Cortex,NSA.NC.TTG.A1 AM=Amygdala,FAM.FT.AM CN=Cochlear Nucleus,LPC.HL.COCH (see Myelencephalic Sensory Nuclei) IC=Inferior Colliculus,ABA.MM.IC (see Reflexes Nuclei of Midbrain Mesencephalon) MGB=Medial Geniculate Body,NSA.FD.TH.MGB OC=Superior Olivary Complex,LPC.MM.SOC PM=Premotor Cortex,NC.PMC SC=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon)
- Oculomotor decision-making - see Reference (CP.OCULOMOTOR-DECISION-MAKING)
AMYG=Amygdala,FAM.FT.AM CGa=Anterior Cingulate Cortex,NC.AL.ACG (see Anterior Cingulate Area) CGp=Posterior Cingulate Cortex,NCP.NC.MPL.PSCG Caudate=Caudate Nucleus,FEC.FT.CN (see Basal Ganglia) FEF=Frontal Eye Field,NMA.NC.PMC.FEF (see Premotor Cortex) LIP=Lateral Intraparietal Sulcus,NPE.NC.IPS.LIP NAC=Accumbens Nucleus,FEC.FT.ACC (see Basal Ganglia) OFC=Orbitofrontal Cortex,NC.AL.OPFC (see Orbitomedial Prefrontal Cortex) PFC=Mid-Dorsolateral Prefrontal Cortex,NDM.NC.AL.DLPFC (see Lateral Prefrontal Cortex) SC=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon) SEF=Supplementary Eye Field,NPE.NC.SMC.SEF SNc=Substantia Nigra Pars Compacta Lateral,FEC.FT.SNC.LT SNr=Substantia Nigra Pars Reticulata Dorsolateral,FEC.FT.SNR.DL Thalamus=Thalamus,FD.TH VTA=Ventral Tegmental Area,LMC.MM.VTA
- Summary of the main extra-amygdaloid and intra-amygdaloid connections in the rat - see Reference (CF.AM-SUMMARY)
AB=Accessory Basal Amygdaloid Nucleus,FAM.FT.AM.AB B=Basal Amygdaloid Nucleus,FAM.FT.AM.B (see Amygdala) CE=Central Amygdala,FAM.FT.AM.CEA (see Amygdala) L=Lateral Amygdaloid Nucleus,FAM.FT.AM.LA (see Amygdala) M=Medial Amygdala,FAM.FT.AM.M (see Amygdala)
- Neuronal projections in the hippocampus - see Reference (CF.AM-HC)
BLA=Basolateral Nuclear Complex,FAM.FT.AM.BL (see Amygdala) CA1=Ventrolateral Cornu Ammonis of Hippocampus,FMM.FT.HC.CA1 (see Hippocampal Formation) CA3=Dorsomedial Cornu Ammonis of Hippocampus,FMM.FT.HC.CA3 (see Hippocampal Formation) DG=Dentate Gyrus,FMM.FT.HC.DG ET=Entorhinal Cortex,FMM.NC.PH.ET (see Rhinal Cortex)
References
(generated)
- http://highered.mcgraw-hill.com/sites/dl/free/0071402357/156721/figure350_1.html
- http://f1000research.com/articles/2-20/v1
- http://www.springerimages.com/Images/LifeSciences/1-10.1007_s00359-004-0565-9-0
- http://journal.frontiersin.org/article/10.3389/fphar.2014.00068/full
- http://journal.frontiersin.org/Journal/10.3389/fpsyt.2013.00061/full