BrainAreaFMM

Forebrain Memory Management Area

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Local Circuits

(generated)

ID	Name	Regions
MMAHCE	Emotional Hippocampus	FMM.FT.HC.CA1D, FMM.FT.HC.CA3P, FMM.FT.HF.SUBP
MMAHCF	Creating Fields	FMM.FT.HC.CA2, FMM.FT.HC.DG
MMAHCS	Spatial Hippocampus	FMM.FT.HC.CA1P, FMM.FT.HC.CA3D, FMM.FT.HF.SUBD
MMAHCT	Thalamic Hippocampus	FMM.FD.TH.RE, FMM.FT.HC.CA1M, FMM.FT.HC.CA3M, FMM.FT.HF.SUBM
MMAORIENT	Orienting Control	FMM.FD.MB.LMB, FMM.FD.TH.AD, FMM.NC.PH.POS
MMASENSE	Emotional Sensory Input to Hippocampus	FMM.NC.PH.LEC, FMM.NC.PH.PER
MMASENSS	Spatial Sensory Input to Hippocampus	FMM.NC.PH.MEC, FMM.NC.PH.POR
MMATHETA	Theta Waves Control	FMM.FD.MB.MMB, FMM.FD.TH.AV, FMM.FD.TH.LD, FMM.NC.PH.PAS, FMM.NC.PH.PRS

Emotional Hippocampus

Component ID	Component Name	Type	Service	Function	Comments
FMM.FT.HC.CA1D	Distal CA1 of Hippocampus	cortex	FMU	Long-term memory, motivational
FMM.FT.HC.CA3P	Proximal CA1 of Hippocampus	cortex	FMU	Representing sequences of episodic memory, spatial
FMM.FT.HF.SUBP	Proximal Subiculum	cortex	FMU	Controlling hypothalamic-pituitary-adrenal (HPA) axis

Internal Region Connections:

Source Region	Target Region	Type	Reference
FMM.FT.HC.CA1D	FMM.FT.HF.SUBP	allocortex-allocortex	[Network in Hippocampus (CA1 -> SUB, abstract)]
FMM.FT.HC.CA3P	FMM.FT.HC.CA1D	allocortex-allocortex	[projections in the hippocampus (CA3 -> CA1, abstract)]

External Inbound Region Connections:

Source Area	Local Region	Source Region	Source Name	Type	Reference
Subcortical
FAM	FMM.FT.HF.SUBP	FAM.FT.SEP.BAC	Bed Nucleus of Anterior Commissure	nucleus-allocortex	[mammillary nucleus and theta rhythm (SEP -> HF, abstract)]
FEC	FMM.FT.HF.SUBP	FEC.FD.TH.RH	Rhomboidal Nucleus of Thalamus	nucleus-allocortex	[of Diencephalon to Recognition Memory (MID -> SubPrePara, abstract)]
FMM	FMM.FT.HC.CA1D	FMM.FT.HC.CA2	Dorsolateral Cornu Ammonis of Hippocampus	allocortex-allocortex	[of impulses in hippocampal region (CA2 -> CA1, abstract)]
		FMM.NC.PH.LEC	Lateral Entorhinal Cortex	neocortex-allocortex	[projections in the hippocampus (ET -> CA1, abstract)]
	FMM.FT.HC.CA3P	FMM.FT.HC.DG	Dentate Gyrus	allocortex-allocortex	[projections in the hippocampus (DG -> CA3, abstract)]
	FMM.FT.HF.SUBP	FMM.NC.PH.LEC	Lateral Entorhinal Cortex	neocortex-allocortex	[Path to Hippocampus (ER -> H, abstract)]
		FMM.NC.PH.PER	Perirhinal Cortex	neocortex-allocortex	[sensory system of rat and macaque (PrC -> HF, abstract)]
LAC	FMM.FT.HC.CA3P	LAC.FD.HT.PN	Posterior Hypothalamic Nucleus	nucleus-allocortex	(unknown reference)
		LAC.FD.HT.SUM	Supramammillary Nucleus	nucleus-allocortex	[mammillary nucleus and theta rhythm (SupraMM -> HF, abstract)]
LMC	FMM.FT.HC.CA1D	LMC.MM.VTA	Ventral Tegmental Area	nucleus-allocortex-DA	[circuit of human brain (VTA -> HC, abstract)]

External Outbound Region Connections:

Target Area	Local Region	Target Region	Target Name	Type	Reference
Cortical
NDM	FMM.FT.HC.CA1D	NDM.NC.AL.ROFCR	Most Rostral Orbitofrontal Cortex	allocortex-neocortex	[model of hippocampal formation anatomy (CA1 -> mPFC, abstract)]
Subcortical
FAM	FMM.FT.HC.CA1D	FAM.FT.SEP.MED	Medial Septal Nucleus	allocortex-nucleus	[Network in Hippocampus (CA1 -> SEP, abstract)]
	FMM.FT.HF.SUBP	FAM.FT.AM.AB	Accessory Basal Amygdaloid Nucleus	allocortex-nucleus	[model of hippocampal formation anatomy (SUB -> Amyg, abstract)]
FEC	FMM.FT.HF.SUBP	FEC.FT.ACC.CORE	Nucleus Accumbens Core	allocortex-nucleus	[Accumbens (SUB -> NACC, abstract)]
FMM	FMM.FT.HC.CA3P	FMM.FT.HC.CA2	Dorsolateral Cornu Ammonis of Hippocampus	allocortex-allocortex-gaba	[model of cortico-hippocampal formation with subcortical projections for motor actions (CA3 -> CA2, abstract)]
	FMM.FT.HF.SUBP	FMM.FD.MB.MMB	Medial Mammillary Nucleus	allocortex-nucleus	[bodies: two memory systems in one (SUB -> MMB, abstract)]
LAC	FMM.FT.HC.CA1D	LAC.FD.HT.PO	Preoptic Nucleus	allocortex-nucleus	[(HC -> HT, abstract)]
	FMM.FT.HF.SUBP	LAC.FD.HT.AH	Anterior Hypothalamic Nucleus	allocortex-nucleus	(unknown reference)
		LAC.FD.HT.VM	Ventromedial Hypothalamic Nucleus	allocortex-nucleus	(unknown reference)

Creating Fields

Component ID	Component Name	Type	Service	Function	Comments
FMM.FT.HC.CA2	Dorsolateral Cornu Ammonis of Hippocampus	cortex	FMU	Gate controlled by the activity of the supramammillary nucleus to control signal propagation between HC lamines	Hippocampus. Receives theta rithm input from Septum Nucleus; the only SUM projection in rat, the only converge from ET L2 and L3; social memory
FMM.FT.HC.DG	Dentate Gyrus	cortex	FMU	Distinguishing multiple instances of similar events

Internal Region Connections:

• no connections

External Inbound Region Connections:

Source Area	Local Region	Source Region	Source Name	Type	Reference
Subcortical
FAM	FMM.FT.HC.CA2	FAM.FT.SEP.DBB	Diagonal Band of Broca	nucleus-allocortex-gaba	[mammillary nucleus and theta rhythm (SEP -> HF, abstract)]
FMM	FMM.FT.HC.CA2	FMM.FT.HC.CA3D	Distal CA1 of Hippocampus	allocortex-allocortex-gaba	[model of cortico-hippocampal formation with subcortical projections for motor actions (CA3 -> CA2, abstract)]
		FMM.FT.HC.CA3M	Middle CA1 of Hippocampus	allocortex-allocortex-gaba	[model of cortico-hippocampal formation with subcortical projections for motor actions (CA3 -> CA2, abstract)]
		FMM.FT.HC.CA3P	Proximal CA1 of Hippocampus	allocortex-allocortex-gaba	[model of cortico-hippocampal formation with subcortical projections for motor actions (CA3 -> CA2, abstract)]
		FMM.NC.PH.LEC	Lateral Entorhinal Cortex	neocortex-allocortex	[and its network (EC -> HC, abstract)]
		FMM.NC.PH.MEC	Medial Entorhinal Cortex	neocortex-allocortex	[and its network (EC -> HC, abstract)]
	FMM.FT.HC.DG	FMM.NC.PH.LEC	Lateral Entorhinal Cortex	neocortex-allocortex	[projections in the hippocampus (ET -> DG, abstract)]
		FMM.NC.PH.MEC	Medial Entorhinal Cortex	neocortex-allocortex	[projections in the hippocampus (ET -> DG, abstract)]
		FMM.NC.PH.PER	Perirhinal Cortex	neocortex-allocortex	[sensory system of rat and macaque (PrC -> HF, abstract)]
LAC	FMM.FT.HC.CA2	LAC.FD.HT.SUM	Supramammillary Nucleus	nucleus-allocortex	[mammillary nucleus and theta rhythm (SupraMM -> HF, abstract)]
	FMM.FT.HC.DG	LAC.FD.HT.PN	Posterior Hypothalamic Nucleus	nucleus-allocortex	(unknown reference)
		LAC.FD.HT.SUM	Supramammillary Nucleus	nucleus-allocortex	[mammillary nucleus and theta rhythm (SupraMM -> HF, abstract)]
LRC	FMM.FT.HC.DG	LRC.HP.PN.SC	Nucleus Subceruleus	nucleus-allocortex	(unknown reference)

External Outbound Region Connections:

Target Area	Local Region	Target Region	Target Name	Type	Reference
Subcortical
FMM	FMM.FT.HC.CA2	FMM.FT.HC.CA1D	Distal CA1 of Hippocampus	allocortex-allocortex	[of impulses in hippocampal region (CA2 -> CA1, abstract)]
		FMM.FT.HC.CA1M	Middle CA1 of Hippocampus	allocortex-allocortex	[of impulses in hippocampal region (CA2 -> CA1, abstract)]
		FMM.FT.HC.CA1P	Proximal CA1 of Hippocampus	allocortex-allocortex	[of impulses in hippocampal region (CA2 -> CA1, abstract)]
	FMM.FT.HC.DG	FMM.FT.HC.CA3D	Distal CA1 of Hippocampus	allocortex-allocortex	[projections in the hippocampus (DG -> CA3, abstract)]
		FMM.FT.HC.CA3M	Middle CA1 of Hippocampus	allocortex-allocortex	[projections in the hippocampus (DG -> CA3, abstract)]
		FMM.FT.HC.CA3P	Proximal CA1 of Hippocampus	allocortex-allocortex	[projections in the hippocampus (DG -> CA3, abstract)]

Spatial Hippocampus

Component ID	Component Name	Type	Service	Function	Comments
FMM.FT.HC.CA1P	Proximal CA1 of Hippocampus	cortex	FMU	Long-term memory, spatial
FMM.FT.HC.CA3D	Distal CA1 of Hippocampus	cortex	FMU	Representing sequences of episodic memory, motivational
FMM.FT.HF.SUBD	Distal Subiculum	cortex	FMU	Providing coarse representation of space

Internal Region Connections:

Source Region	Target Region	Type	Reference
FMM.FT.HC.CA1P	FMM.FT.HF.SUBD	allocortex-allocortex	[Network in Hippocampus (CA1 -> SUB, abstract)]
FMM.FT.HC.CA3D	FMM.FT.HC.CA1P	allocortex-allocortex	[projections in the hippocampus (CA3 -> CA1, abstract)]

External Inbound Region Connections:

Source Area	Local Region	Source Region	Source Name	Type	Reference
Cortical
NCP	FMM.FT.HC.CA1P	NCP.NC.MPL.PSCG	Posterior Cingulate Cortex	neocortex-allocortex	[(CG -> HC, abstract)]
	FMM.FT.HC.CA3D	NCP.NC.MPL.RSC	Retrosplenial Cortex	neocortex-allocortex	[Cortex (PFC) in emotional behavior (PCA -> HCA, abstract)]
NPE	FMM.FT.HC.CA3D	NPE.NC.IPL.MST	Medial Superior Temporal Area	neocortex-allocortex	[of hippocampal region CA3 to consciousness (IPL -> CA1, abstract)]
Subcortical
FMM	FMM.FT.HC.CA1P	FMM.FD.TH.AV	Anteroventral Nucleus	nucleus-allocortex	[of Diencephalon to Recognition Memory (AN -> HC, abstract)]
		FMM.FD.TH.LD	Lateral Dorsal Nucleus of Thalamus	nucleus-allocortex	[of Diencephalon to Recognition Memory (LD -> HC, abstract)]
		FMM.FT.HC.CA2	Dorsolateral Cornu Ammonis of Hippocampus	allocortex-allocortex	[of impulses in hippocampal region (CA2 -> CA1, abstract)]
		FMM.NC.PH.MEC	Medial Entorhinal Cortex	neocortex-allocortex	[projections in the hippocampus (ET -> CA1, abstract)]
	FMM.FT.HC.CA3D	FMM.FT.HC.DG	Dentate Gyrus	allocortex-allocortex	[projections in the hippocampus (DG -> CA3, abstract)]
	FMM.FT.HF.SUBD	FMM.NC.PH.POR	Postrhinal Cortex	neocortex-allocortex	(unknown reference)

External Outbound Region Connections:

Target Area	Local Region	Target Region	Target Name	Type	Reference
Cortical
NCP	FMM.FT.HF.SUBD	NCP.NC.MPL.RSC	Retrosplenial Cortex	allocortex-neocortex	[Spatial Processing Network (SUB -> PCGRSP, abstract)]
NDM	FMM.FT.HF.SUBD	NDM.NC.AL.ROFCR	Most Rostral Orbitofrontal Cortex	allocortex-neocortex	[model of hippocampal formation anatomy (SUB -> mPFC, abstract)]
Subcortical
FAM	FMM.FT.HC.CA3D	FAM.FT.SEP.SF	Septofimbrial Nucleus	allocortex-nucleus	[Gyrus (HC -> SEP, abstract)]
	FMM.FT.HF.SUBD	FAM.FT.AM.AB	Accessory Basal Amygdaloid Nucleus	allocortex-nucleus	[model of hippocampal formation anatomy (SUB -> Amyg, abstract)]
		FAM.FT.SEP.TR	Triangular Septal Nucleus	allocortex-nucleus	[mammillary nucleus and theta rhythm (HF -> SEP, abstract)]
FEC	FMM.FT.HF.SUBD	FEC.FT.ACC.CORE	Nucleus Accumbens Core	allocortex-nucleus	[Accumbens (SUB -> NACC, abstract)]
FMM	FMM.FT.HC.CA1P	FMM.NC.PH.PAS	Parasubiculum	allocortex-neocortex	(unknown reference)
		FMM.NC.PH.POR	Postrhinal Cortex	allocortex-neocortex	[Cortex Inputs and Outputs (CA1 -> TFTH, abstract)]
	FMM.FT.HC.CA3D	FMM.FT.HC.CA2	Dorsolateral Cornu Ammonis of Hippocampus	allocortex-allocortex-gaba	[model of cortico-hippocampal formation with subcortical projections for motor actions (CA3 -> CA2, abstract)]
	FMM.FT.HF.SUBD	FMM.FD.MB.MMB	Medial Mammillary Nucleus	allocortex-nucleus	[bodies: two memory systems in one (SUB -> MMB, abstract)]
		FMM.FD.TH.AV	Anteroventral Nucleus	allocortex-nucleus	[relationships (s1A -> A, abstract)]
		FMM.FD.TH.LD	Lateral Dorsal Nucleus of Thalamus	allocortex-nucleus	[of Diencephalon to Recognition Memory (Sub -> LD, abstract)]
		FMM.NC.PH.LEC	Lateral Entorhinal Cortex	allocortex-neocortex	[Network in Hippocampus (SUB -> EC, abstract)]
		FMM.NC.PH.MEC	Medial Entorhinal Cortex	allocortex-neocortex	[Network in Hippocampus (SUB -> EC, abstract)]
		FMM.NC.PH.POS	Postsubiculum	allocortex-neocortex	[Formation (Sub -> PoS, abstract)]
		FMM.NC.PH.PRS	Presubiculum	allocortex-neocortex	[Network in Hippocampus (SUB -> PRESUB, abstract)]
LAC	FMM.FT.HF.SUBD	LAC.FD.HT.PV	Paraventricular Nucleus	allocortex-nucleus	(unknown reference)

Thalamic Hippocampus

Component ID	Component Name	Type	Service	Function	Comments
FMM.FD.TH.RE	Reuniens Nucleus of Thalamus	nucleus	FMU	Gate information between OMPFC and HC dependent upon attentive/arousal states	Regulate amount of neural traffic with changes in attentiveness
FMM.FT.HC.CA1M	Middle CA1 of Hippocampus	cortex	FMU	Long-term memory, synchronize
FMM.FT.HC.CA3M	Middle CA1 of Hippocampus	cortex	FMU	Representing sequences of episodic memory, synchronize
FMM.FT.HF.SUBM	Middle Subiculum	cortex	FMU	Dynamic bridging of temporal intervals

Internal Region Connections:

Source Region	Target Region	Type	Reference
FMM.FD.TH.RE	FMM.FT.HC.CA1M	nucleus-allocortex	[of Diencephalon to Recognition Memory (MID -> HC, abstract)]
FMM.FT.HC.CA1M	FMM.FT.HF.SUBM	allocortex-allocortex	[Network in Hippocampus (CA1 -> SUB, abstract)]
FMM.FT.HC.CA3M	FMM.FT.HC.CA1M	allocortex-allocortex	[projections in the hippocampus (CA3 -> CA1, abstract)]
FMM.FT.HF.SUBM	FMM.FD.TH.RE	allocortex-nucleus	[of Diencephalon to Recognition Memory (Sub -> MID, abstract)]

External Inbound Region Connections:

Source Area	Local Region	Source Region	Source Name	Type	Reference
Cortical
NDM	FMM.FD.TH.RE	NDM.NC.AL.ROFCR	Most Rostral Orbitofrontal Cortex	neocortex-nucleus	(unknown reference)
Subcortical
FAM	FMM.FD.TH.RE	FAM.FT.AM.MPV	Medial Posteror Ventral Amygdaloid Nucleus	nucleus-nucleus-gaba	[decision-making (AMYG -> Thalamus, abstract)]
FMM	FMM.FT.HC.CA1M	FMM.FT.HC.CA2	Dorsolateral Cornu Ammonis of Hippocampus	allocortex-allocortex	[of impulses in hippocampal region (CA2 -> CA1, abstract)]
	FMM.FT.HC.CA3M	FMM.FT.HC.DG	Dentate Gyrus	allocortex-allocortex	[projections in the hippocampus (DG -> CA3, abstract)]

External Outbound Region Connections:

Target Area	Local Region	Target Region	Target Name	Type	Reference
Cortical
NCP	FMM.FT.HF.SUBM	NCP.FD.TH.AM	Anteromedial Nucleus	allocortex-nucleus	[relationships (s1A -> A, abstract)]
Subcortical
FMM	FMM.FT.HC.CA3M	FMM.FT.HC.CA2	Dorsolateral Cornu Ammonis of Hippocampus	allocortex-allocortex-gaba	[model of cortico-hippocampal formation with subcortical projections for motor actions (CA3 -> CA2, abstract)]

Orienting Control

Component ID	Component Name	Type	Service	Function	Comments
FMM.FD.MB.LMB	Lateral Mammillary Nucleus	nucleus	FMU	Generate theta rythm and relay to HC	Memory, recognition, spatial awareness, and interpreting the context of events
FMM.FD.TH.AD	Anterodorsal Nucleus	nucleus	NPU	head direction, spatial learning and memory
FMM.NC.PH.POS	Postsubiculum	cortex, BA 48	FMU	Visual association	Detached dorsal part of presubiculum; Integrate visual landmarks with internal representations of environments

Internal Region Connections:

Source Region	Target Region	Type	Reference
FMM.FD.MB.LMB	FMM.FD.TH.AD	nucleus-nucleus	[Direction Cell Circuit (LMB -> AD)]
FMM.FD.TH.AD	FMM.NC.PH.POS	nucleus-neocortex	[Direction Cell Circuit (AD -> PSUB)]
FMM.NC.PH.POS	FMM.FD.MB.LMB	neocortex-nucleus	[Direction Cell Circuit (PSUB -> LMB)]

External Inbound Region Connections:

Source Area	Local Region	Source Region	Source Name	Type	Reference
Cortical
NCP	FMM.FD.TH.AD	NCP.NC.MPL.RSC	Retrosplenial Cortex	neocortex-nucleus	[Direction Cell Circuit (RSP -> AD)]
	FMM.NC.PH.POS	NCP.NC.MPL.RSC	Retrosplenial Cortex	neocortex-neocortex	[Direction Cell Circuit (RSP -> PSUB)]
NSA	FMM.NC.PH.POS	NSA.NC.OCC.V2TK	Secondary Visual Cortex, Thick Stripe	neocortex-neocortex	[Direction Cell Circuit (VC -> PSUB, abstract)]
Subcortical
FAM	FMM.FD.MB.LMB	FAM.FT.SEP.MED	Medial Septal Nucleus	nucleus-nucleus-ACh	[Gyrus (SEP -> HT, abstract)]
FMM	FMM.FD.MB.LMB	FMM.NC.PH.PAS	Parasubiculum	neocortex-nucleus	[bodies: two memory systems in one (PAS -> LMB)]
		FMM.NC.PH.PRS	Presubiculum	neocortex-nucleus	[bodies: two memory systems in one (PRS -> LMB)]
	FMM.NC.PH.POS	FMM.FD.TH.LD	Lateral Dorsal Nucleus of Thalamus	nucleus-neocortex	[Direction Cell Circuit (LD -> PSUB)]
		FMM.FT.HF.SUBD	Distal Subiculum	allocortex-neocortex	[Formation (Sub -> PoS, abstract)]
LAC	FMM.FD.MB.LMB	LAC.FD.HT.LTN	Lateral Hypothalamic Nucleus	nucleus-nucleus	(unknown reference)
		LAC.FD.HT.PN	Posterior Hypothalamic Nucleus	nucleus-nucleus	(unknown reference)
LMC	FMM.FD.MB.LMB	LMC.HP.TG.DTG	Dorsal Tegmental Nucleus	nucleus-nucleus-ACh	(unknown reference)

External Outbound Region Connections:

Target Area	Local Region	Target Region	Target Name	Type	Reference
Subcortical
FMM	FMM.NC.PH.POS	FMM.NC.PH.MEC	Medial Entorhinal Cortex	neocortex-neocortex	[Direction Cell Circuit (PSUB -> EC, abstract)]
LLC	FMM.FD.MB.LMB	LLC.HP.PRF.PDT	Pontine Reticulotegmental Nucleus	nucleus-nucleus	[Body (LMB -> RTG)]
LMC	FMM.FD.MB.LMB	LMC.HP.TG.LDT	Laterodorsal Tegmental Nucleus	nucleus-nucleus	[Direction Cell Circuit (LMB -> DTN)]

Emotional Sensory Input to Hippocampus

Component ID	Component Name	Type	Service	Function	Comments
FMM.NC.PH.LEC	Lateral Entorhinal Cortex	cortex, BA 28	FMU	Memory consolidation, emotioncal aspects	non-spatial input to HC; process information about individual items and locations based on a local frame of reference, primarily using external sensory input; it provides the hippocampus with information about content of experience
FMM.NC.PH.PER	Perirhinal Cortex	cortex, BA 35,36	FMU	Associate different visual views of objects and their various nonvisual attributes

Internal Region Connections:

Source Region	Target Region	Type	Reference
FMM.NC.PH.PER	FMM.NC.PH.LEC	neocortex-neocortex	[Path to Hippocampus (PRPH -> ER, abstract)]

External Inbound Region Connections:

Source Area	Local Region	Source Region	Source Name	Type	Reference
Cortical
NCP	FMM.NC.PH.PER	NCP.NC.INS.AIC	Anterior Insular Cortex	neocortex-neocortex	[sensory system of rat and macaque (Iav -> PrC, abstract)]
		NCP.NC.INS.HR	Anterior Temporal Lobe	neocortex-neocortex	[of hippocampal region CA3 to consciousness (AnteriorTemporal -> PRCortex)]
NSA	FMM.NC.PH.LEC	NSA.NC.IT.TE	Inferotemporal Cortex	neocortex-neocortex	[Spatial Processing Network (ITCortex -> EnthCortex, abstract)]
		NSA.NC.PH.PIR	Piriform Cortex	neocortex-neocortex	[model of cortico-hippocampal formation with subcortical projections for motor actions (PC -> EC, abstract)]
		NSA.NC.STG.A3	Wernicke's area A3	neocortex-neocortex	(unknown reference)
		NSA.NC.STG.A4	Wernicke's area A4	neocortex-neocortex	(unknown reference)
	FMM.NC.PH.PER	NSA.NC.IT.TE	Inferotemporal Cortex	neocortex-neocortex	[Path to Hippocampus (IT -> PRPH)]
		NSA.NC.PG.PV	Parietal Ventral Cortex	neocortex-neocortex	(unknown reference)
Subcortical
FAM	FMM.NC.PH.LEC	FAM.FD.TH.PT	Paratenial Nucleus of Thalamus	nucleus-neocortex	[of Diencephalon to Recognition Memory (MID -> EC, abstract)]
		FAM.FT.AM.BP	Parvicellular Basal Amygdaloid Nucleus	nucleus-neocortex	[Connections of Hippocampus (AM -> EC, abstract)]
	FMM.NC.PH.PER	FAM.HP.NI	Incertus Nucleus	nucleus-neocortex-gaba	(unknown reference)
FMM	FMM.NC.PH.LEC	FMM.FT.HF.SUBD	Distal Subiculum	allocortex-neocortex	[Network in Hippocampus (SUB -> EC, abstract)]
LMC	FMM.NC.PH.LEC	LMC.MM.VTA	Ventral Tegmental Area	nucleus-neocortex-DA	[Novelty, Motivational Salience, and Reward to Control Attention and Learning (VTA -> EC, abstract)]
LPC	FMM.NC.PH.LEC	LPC.FD.TH.PV	Paraventricular Nucleus of Thalamus	nucleus-neocortex	[of Diencephalon to Recognition Memory (MID -> EC, abstract)]
	FMM.NC.PH.PER	LPC.FD.TH.PV	Paraventricular Nucleus of Thalamus	nucleus-neocortex	[of Diencephalon to Recognition Memory (MID -> Perirhinal, abstract)]

External Outbound Region Connections:

Target Area	Local Region	Target Region	Target Name	Type	Reference
Cortical
NDM	FMM.NC.PH.LEC	NDM.FD.TH.MDM	Medial Mediodorsal Nucleus of Thalamus	neocortex-nucleus	[of Diencephalon to Recognition Memory (EC -> MDmc, abstract)]
	FMM.NC.PH.PER	NDM.FD.TH.MDM	Medial Mediodorsal Nucleus of Thalamus	neocortex-nucleus	[of Diencephalon to Recognition Memory (Perirhinal -> MDmc, abstract)]
NPE	FMM.NC.PH.PER	NPE.FD.TH.MPV	Medial Pulvinar	neocortex-nucleus	[of Diencephalon to Recognition Memory (Perirhinal -> mPULV)]
Subcortical
FAM	FMM.NC.PH.LEC	FAM.FT.AM.AB	Accessory Basal Amygdaloid Nucleus	neocortex-nucleus	[model of hippocampal formation anatomy (EC -> Amyg, abstract)]
FEC	FMM.NC.PH.LEC	FEC.FT.ACC.CORE	Nucleus Accumbens Core	neocortex-nucleus	[Accumbens (EC -> NACC, abstract)]
	FMM.NC.PH.PER	FEC.FT.ACC.CORE	Nucleus Accumbens Core	neocortex-nucleus	[Accumbens (PRR -> NACC, abstract)]
FMM	FMM.NC.PH.LEC	FMM.FT.HC.CA1D	Distal CA1 of Hippocampus	neocortex-allocortex	[projections in the hippocampus (ET -> CA1, abstract)]
		FMM.FT.HC.CA2	Dorsolateral Cornu Ammonis of Hippocampus	neocortex-allocortex	[and its network (EC -> HC, abstract)]
		FMM.FT.HC.DG	Dentate Gyrus	neocortex-allocortex	[projections in the hippocampus (ET -> DG, abstract)]
		FMM.FT.HF.SUBP	Proximal Subiculum	neocortex-allocortex	[Path to Hippocampus (ER -> H, abstract)]
	FMM.NC.PH.PER	FMM.FT.HC.DG	Dentate Gyrus	neocortex-allocortex	[sensory system of rat and macaque (PrC -> HF, abstract)]
		FMM.FT.HF.SUBP	Proximal Subiculum	neocortex-allocortex	[sensory system of rat and macaque (PrC -> HF, abstract)]

Spatial Sensory Input to Hippocampus

Component ID	Component Name	Type	Service	Function	Comments
FMM.NC.PH.MEC	Medial Entorhinal Cortex	cortex, BA 28	FMU	Memory consolidation, basic, view inpedepdent position	spatial input to HC; grid cells; path integration computations based on a global frame of reference, primarily using internally generated, self-motion cues and external input about environmental boundaries and scenes; provides hippocampus with coordinate system that underlies spatial context of experience
FMM.NC.PH.POR	Postrhinal Cortex	cortex, BA 29,30	FMU	Spatial declarative memory

Internal Region Connections:

Source Region	Target Region	Type	Reference
FMM.NC.PH.POR	FMM.NC.PH.MEC	neocortex-neocortex	[Cortex Inputs and Outputs (TFTH -> EC, abstract)]

External Inbound Region Connections:

Source Area	Local Region	Source Region	Source Name	Type	Reference
Cortical
NCP	FMM.NC.PH.MEC	NCP.NC.MPL.PSCG	Posterior Cingulate Cortex	neocortex-neocortex	[Spatial Processing Network (PCGRSP -> EnthCortex, abstract)]
		NCP.NC.MPL.RSC	Retrosplenial Cortex	neocortex-neocortex	[Spatial Processing Network (PCGRSP -> EnthCortex, abstract)]
NPE	FMM.NC.PH.POR	NPE.NC.IPL.MST	Medial Superior Temporal Area	neocortex-neocortex	[Direction Cell Circuit (PC -> PRHC, abstract)]
Subcortical
FMM	FMM.NC.PH.MEC	FMM.FT.HF.SUBD	Distal Subiculum	allocortex-neocortex	[Network in Hippocampus (SUB -> EC, abstract)]
		FMM.NC.PH.PAS	Parasubiculum	neocortex-neocortex	(unknown reference)
		FMM.NC.PH.POS	Postsubiculum	neocortex-neocortex	[Direction Cell Circuit (PSUB -> EC, abstract)]
		FMM.NC.PH.PRS	Presubiculum	neocortex-neocortex	[Network in Hippocampus (PRESUB -> EC, abstract)]
	FMM.NC.PH.POR	FMM.FT.HC.CA1P	Proximal CA1 of Hippocampus	allocortex-neocortex	[Cortex Inputs and Outputs (CA1 -> TFTH, abstract)]

External Outbound Region Connections:

Target Area	Local Region	Target Region	Target Name	Type	Reference
Subcortical
FMM	FMM.NC.PH.MEC	FMM.FD.MB.MMB	Medial Mammillary Nucleus	neocortex-nucleus	[bodies: two memory systems in one (MedialEC -> MMB, abstract)]
		FMM.FD.TH.LD	Lateral Dorsal Nucleus of Thalamus	neocortex-nucleus	[of Diencephalon to Recognition Memory (EC -> LD, abstract)]
		FMM.FT.HC.CA1P	Proximal CA1 of Hippocampus	neocortex-allocortex	[projections in the hippocampus (ET -> CA1, abstract)]
		FMM.FT.HC.CA2	Dorsolateral Cornu Ammonis of Hippocampus	neocortex-allocortex	[and its network (EC -> HC, abstract)]
		FMM.FT.HC.DG	Dentate Gyrus	neocortex-allocortex	[projections in the hippocampus (ET -> DG, abstract)]
	FMM.NC.PH.POR	FMM.FT.HF.SUBD	Distal Subiculum	neocortex-allocortex	(unknown reference)

Theta Waves Control

Component ID	Component Name	Type	Service	Function	Comments
FMM.FD.MB.MMB	Medial Mammillary Nucleus	nucleus	FMU	Relay for impulses coming from AM and HC	Memory, recognition, spatial awareness, and interpreting the context of events
FMM.FD.TH.AV	Anteroventral Nucleus	nucleus	NPU	return loop to convey theta to to HF, attentional processes
FMM.FD.TH.LD	Lateral Dorsal Nucleus of Thalamus	nucleus	NPU	Head direction, spatial learning	From RSP L5,6 BA17,18, RT, LGN
FMM.NC.PH.PAS	Parasubiculum	cortex, BA 49	FMU	Spatial navigation and the integration of head-directional information	Major projects to ET, from CA1,AM
FMM.NC.PH.PRS	Presubiculum	cortex, BA 27	FMU	Path integration, head direction	Major projects to ET, from TH.LD

Internal Region Connections:

Source Region	Target Region	Type	Reference
FMM.FD.MB.MMB	FMM.FD.TH.AV	nucleus-nucleus	[bodies: two memory systems in one (MMB -> AVTH)]
FMM.FD.TH.AV	FMM.NC.PH.PAS	nucleus-neocortex	(unknown reference)
	FMM.NC.PH.PRS	nucleus-neocortex	(unknown reference)
FMM.NC.PH.PAS	FMM.FD.TH.LD	neocortex-nucleus	[of Diencephalon to Recognition Memory (Parasub -> LD)]
FMM.NC.PH.PRS	FMM.FD.MB.MMB	neocortex-nucleus	[Network in Hippocampus (PRESUB -> MBIN)]
	FMM.FD.TH.LD	neocortex-nucleus	[of Diencephalon to Recognition Memory (Presub -> LD)]

External Inbound Region Connections:

Source Area	Local Region	Source Region	Source Name	Type	Reference
Cortical
NCP	FMM.FD.TH.AV	NCP.NC.MPL.RSC	Retrosplenial Cortex	neocortex-nucleus	[mammillary nucleus and theta rhythm (RSP -> AVTH)]
	FMM.FD.TH.LD	NCP.NC.MPL.RSC	Retrosplenial Cortex	neocortex-nucleus	[Direction Cell Circuit (RSP -> LD)]
	FMM.NC.PH.PRS	NCP.NC.INS.PPC	Peripaleocortical Claustral	neocortex-neocortex	(unknown reference)
NPE	FMM.FD.TH.LD	NPE.NC.SPL.PF	Rostral Precuneus	neocortex-nucleus	[relationships (sLD -> LD, abstract)]
Subcortical
FAM	FMM.FD.MB.MMB	FAM.FT.SEP.DBB	Diagonal Band of Broca	nucleus-nucleus-gaba	[Gyrus (SEP -> HT, abstract)]
		FAM.FT.SEP.MED	Medial Septal Nucleus	nucleus-nucleus-gaba	[Gyrus (SEP -> HT, abstract)]
	FMM.NC.PH.PAS	FAM.FT.AM.AB	Accessory Basal Amygdaloid Nucleus	nucleus-neocortex	(unknown reference)
FMM	FMM.FD.MB.MMB	FMM.FT.HF.SUBD	Distal Subiculum	allocortex-nucleus	[bodies: two memory systems in one (SUB -> MMB, abstract)]
		FMM.FT.HF.SUBP	Proximal Subiculum	allocortex-nucleus	[bodies: two memory systems in one (SUB -> MMB, abstract)]
		FMM.NC.PH.MEC	Medial Entorhinal Cortex	neocortex-nucleus	[bodies: two memory systems in one (MedialEC -> MMB, abstract)]
	FMM.FD.TH.AV	FMM.FT.HF.SUBD	Distal Subiculum	allocortex-nucleus	[relationships (s1A -> A, abstract)]
	FMM.FD.TH.LD	FMM.FT.HF.SUBD	Distal Subiculum	allocortex-nucleus	[of Diencephalon to Recognition Memory (Sub -> LD, abstract)]
		FMM.NC.PH.MEC	Medial Entorhinal Cortex	neocortex-nucleus	[of Diencephalon to Recognition Memory (EC -> LD, abstract)]
	FMM.NC.PH.PAS	FMM.FT.HC.CA1P	Proximal CA1 of Hippocampus	allocortex-neocortex	(unknown reference)
	FMM.NC.PH.PRS	FMM.FT.HF.SUBD	Distal Subiculum	allocortex-neocortex	[Network in Hippocampus (SUB -> PRESUB, abstract)]
LAC	FMM.FD.MB.MMB	LAC.FD.HT.LTN	Lateral Hypothalamic Nucleus	nucleus-nucleus	(unknown reference)
		LAC.FD.HT.PN	Posterior Hypothalamic Nucleus	nucleus-nucleus	(unknown reference)
LMC	FMM.FD.MB.MMB	LMC.HP.TG.VTG	Ventral Tegmental Nucleus	nucleus-nucleus	(unknown reference)
		LMC.MM.RF.SUC	Superior Central Raphe Nucleus	nucleus-nucleus-5HT	(unknown reference)
		LMC.MM.VTA	Ventral Tegmental Area	nucleus-nucleus-DA	[bodies: two memory systems in one (VTN -> MMB)]

External Outbound Region Connections:

Target Area	Local Region	Target Region	Target Name	Type	Reference
Cortical
NPE	FMM.NC.PH.PRS	NPE.FD.TH.MPV	Medial Pulvinar	neocortex-nucleus	[of Diencephalon to Recognition Memory (Presub -> mPULV)]
Subcortical
FEC	FMM.NC.PH.PAS	FEC.FT.ACC.CORE	Nucleus Accumbens Core	neocortex-nucleus	[Accumbens (PAS -> NACC, abstract)]
FMM	FMM.FD.TH.AV	FMM.FT.HC.CA1P	Proximal CA1 of Hippocampus	nucleus-allocortex	[of Diencephalon to Recognition Memory (AN -> HC, abstract)]
	FMM.FD.TH.LD	FMM.FT.HC.CA1P	Proximal CA1 of Hippocampus	nucleus-allocortex	[of Diencephalon to Recognition Memory (LD -> HC, abstract)]
		FMM.NC.PH.POS	Postsubiculum	nucleus-neocortex	[Direction Cell Circuit (LD -> PSUB)]
	FMM.NC.PH.PAS	FMM.FD.MB.LMB	Lateral Mammillary Nucleus	neocortex-nucleus	[bodies: two memory systems in one (PAS -> LMB)]
		FMM.NC.PH.MEC	Medial Entorhinal Cortex	neocortex-neocortex	(unknown reference)
	FMM.NC.PH.PRS	FMM.FD.MB.LMB	Lateral Mammillary Nucleus	neocortex-nucleus	[bodies: two memory systems in one (PRS -> LMB)]
		FMM.NC.PH.MEC	Medial Entorhinal Cortex	neocortex-neocortex	[Network in Hippocampus (PRESUB -> EC, abstract)]
LLC	FMM.FD.MB.MMB	LLC.HP.PN.RP	Rostral Pontine Nucleus	nucleus-nucleus	[Cortex (PFC) in emotional behavior (HT -> PN, abstract)]
		LLC.HP.PRF.PDT	Pontine Reticulotegmental Nucleus	nucleus-nucleus	[Body (MMB -> RTG)]

Thirdparty Circuits

(generated)

• [of Diencephalon to Recognition Memory] - see [[1]]

• [bodies: two memory systems in one] - see [[2]]

• [Direction Cell Circuit] - see [[3]]

• [Network in Hippocampus] - see [[4]]

• [Formation] - see Reference

• [of impulses in hippocampal region] - see [[5]]

• [of hippocampal region CA3 to consciousness] - see [[6]]

• [Accumbens] (unknown reference)

• [model of cortico-hippocampal formation with subcortical projections for motor actions] - see [[7]]

• [in Detail] - see [[8]]

• [Connections of Hippocampus] - see [[9]]

• [mammillary nucleus and theta rhythm] - see [[10]]

• [Body] (unknown reference)

• [Cortex Inputs and Outputs] - see [[11]]

• [Path to Hippocampus] - see [[12]]

• [sensory system of rat and macaque] - see [[13]]

• [Nucleus of Meynert] - see Reference

• [model of hippocampal formation anatomy] - see [[14]]

• [Novelty, Motivational Salience, and Reward to Control Attention and Learning] - see [[15]]

• [projections in the hippocampus] - see [[16]]

• [relationships] - see [[17]]

• [and Septal Area] - see [[18]]

References

(generated)

• http://learnmem.cshlp.org/content/18/6/384/F1.expansion.html
• http://www.nature.com/nrn/journal/v5/n1/fig_tab/nrn1299_F2.html
• http://www.scholarpedia.org/article/Head_direction_cells
• http://learnmem.cshlp.org/content/14/11/714/F1.expansion
• article:2009-Hippocampus-Thesis.pdf
• http://www.sciencedirect.com/science/article/pii/S030645220600755X
• http://www.sciencedirect.com/science/article/pii/S0149763409002061
• http://www.sciencedirect.com/science/article/pii/S1571064507000243
• http://what-when-how.com/neuroscience/the-limbic-system-integrative-systems-part-1/
• http://highered.mcgraw-hill.com/sites/dl/free/0071402357/156721/figure350_1.html
• http://www.nature.com/nrn/journal/v5/n1/fig_tab/nrn1299_F4.html
• http://www.sciencedirect.com/science/article/pii/S0149763411001722
• http://www.scholarpedia.org/article/Inferior_temporal_cortex
• http://www.sciencedirect.com/science/article/pii/S0149763401000215
• article:Biological/2005-The-Human-Nervous-System.pdf
• http://www.sciencedirect.com/science/article/pii/S030100820900183X
• http://www.impulsecontroldisorders.org/html/cravings.html
• http://journal.frontiersin.org/Journal/10.3389/fpsyt.2013.00061/full
• http://what-when-how.com/neuroscience/the-thalamus-and-cerebral-cortex-integrative-systems-part-2/
• http://neurondevelopment.org/hippocampal-development