BrainRegionFMM FT HF SUBP
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Proximal Subiculum
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This page covers biological details of component Proximal Subiculum. Region is part of aHuman target integrated biological model.
- Top-down path to region: Forebrain Telencephalon -> Hippocampal Formation (FMM.FT.HF) -> Subiculum (FMM.FT.HF.SUB) -> Proximal Subiculum (FMM.FT.HF.SUBP) (see Mind Maps)
- Type: cortex
- Quality: L0
- Brain area: Forebrain - Memory Management Area (FMM)
- Area circuit: Emotional Hippocampus (MMAHCE)
- Role: processor.memory.sub
- Function: Controlling hypothalamic-pituitary-adrenal (HPA) axis
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Components
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- no child items defined
Connectivity
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Inbound Region Connections:
| Source Area | Source Region | Source Name | Type | Role | Reference |
| FAM | FAM.FT.SEP.BAC | Bed Nucleus of Anterior Commissure | excitatory-glu | uncertain | Medial mammillary nucleus and theta rhythm (SEP -> HF, abstract) |
| FMM | FMM.FD.TH.RH | Rhomboidal Nucleus of Thalamus | excitatory-glu | uncertain | Contributions of Diencephalon to Recognition Memory (MID -> SubPrePara, abstract) |
| FMM.FT.HC.CA1D | Distal CA1 of Hippocampus | excitatory-glu | uncertain | Attractor Network in Hippocampus (CA1 -> SUB, abstract) | |
| FMM.NC.PH.LEC | Lateral Entorhinal Cortex | excitatory-glu | uncertain | Visual Path to Hippocampus (ER -> H, abstract) | |
| FMM.NC.PH.PER | Perirhinal Cortex | excitatory-glu | uncertain | Gustatory sensory system of rat and macaque (PrC -> HF, abstract) |
Outbound Region Connections:
| Target Area | Target Region | Target Name | Type | Role | Reference |
| FAM | FAM.FT.AM.AB | Accessory Basal Amygdaloid Nucleus | excitatory-glu | uncertain | Simplified model of hippocampal formation anatomy (SUB -> Amyg, abstract) |
| FEC | FEC.FT.ACC.CORE | Nucleus Accumbens Core | excitatory-glu | uncertain | Nucleus Accumbens (SUB -> NACC, abstract) |
| FMM | FMM.FD.MB.MMB | Medial Mammillary Nucleus | excitatory-glu | uncertain | Principal Connections of Hippocampus (HC -> MB, abstract) |
| LAC | LAC.FD.HT.AH | Anterior Hypothalamic Nucleus | excitatory-glu | uncertain | (unknown reference) |
| LAC.FD.HT.VM | Ventromedial Hypothalamic Nucleus | excitatory-glu | uncertain | (unknown reference) |
Thirdparty Circuits
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- Contributions of Diencephalon to Recognition Memory - see Reference (CT.RECOGNITION-MEMORY)
AD=Anterodorsal Nucleus,FMM.FD.TH.AD AM=Anteromedial Nucleus,NCP.FD.TH.AM AN=Anterior Nucleus of Thalamus,FD.TH.AN (see Cognitive Thalamus) AV=Anteroventral Nucleus,FMM.FD.TH.AV CM=Centromedian Nucleus of Thalamus,FEC.FD.TH.CM DLPFC=Mid-Dorsolateral Prefrontal Cortex,NDM.NC.AL.DLPFC (see Lateral Prefrontal Cortex) EC=Entorhinal Cortex,FMM.NC.PH.ET (see Rhinal Cortex) HC=Hippocampus,FMM.FT.HC (see Hippocampal Formation) LD=Lateral Dorsal Nucleus of Thalamus,FMM.FD.TH.LD MB=Medial Mammillary Nucleus,FMM.FD.MB.MMB MDmc=Mediodorsal Nucleus of Thalamus,FD.TH.MD (see Cognitive Thalamus) MID=Midline Nuclear Group of Thalamus,FD.TH.MTH (see Cognitive Thalamus) MPFC=Orbitofrontal Cortex,NC.AL.OPFC (see Orbitomedial Prefrontal Cortex) OFC=Orbitofrontal Cortex,NC.AL.OPFC (see Orbitomedial Prefrontal Cortex) Parasub=Parasubiculum,FMM.NC.PH.PAS Perirhinal=Perirhinal Cortex,FMM.NC.PH.PER PostCingulate=Posterior Cingulate Cortex,NCP.NC.MPL.PSCG Presub=Presubiculum,FMM.NC.PH.PRS Sub=Subiculum,FMM.FT.HF.SUB (see Hippocampal Formation) SubPrePara=Subiculum,FMM.FT.HF.SUB (see Hippocampal Formation) mPULV=Medial Pulvinar,NPE.FD.TH.MPV
- Simplified model of hippocampal formation anatomy - see Reference (CT.OPERATING-MODEL)
Amyg=Amygdala,FAM.FT.AM CA1=Ventrolateral Cornu Ammonis of Hippocampus,FMM.FT.HC.CA1 (see Hippocampal Formation) CA3=Dorsomedial Cornu Ammonis of Hippocampus,FMM.FT.HC.CA3 (see Hippocampal Formation) DG=Dentate Gyrus,FMM.FT.HC.DG EC=Entorhinal Cortex,FMM.NC.PH.ET (see Rhinal Cortex) NACC=Accumbens Nucleus,FEC.FT.ACC (see Basal Ganglia) SUB=Subiculum,FMM.FT.HF.SUB (see Hippocampal Formation) mPFC=Orbitofrontal Cortex,NC.AL.OPFC (see Orbitomedial Prefrontal Cortex)
- Principal Connections of Hippocampus - see Reference (CT.CINGULUM-CONNECTIONS)
AM=Amygdala,FAM.FT.AM AN=Anterior Nucleus of Thalamus,FD.TH.AN (see Cognitive Thalamus) DG=Dentate Gyrus,FMM.FT.HC.DG DorsalCingulate=Dorsal Anterior Cingulate Area,NDM.NC.AL.DACG EC=Entorhinal Cortex,FMM.NC.PH.ET (see Rhinal Cortex) HC=Subiculum,FMM.FT.HF.SUB (see Hippocampal Formation) MB=Medial Mammillary Nucleus,FMM.FD.MB.MMB PosteriorCingulate=Posterior Cingulate Cortex,NCP.NC.MPL.PSCG SEP=Septal Nuclei,FAM.FT.SEP SUB=Subiculum,FMM.FT.HF.SUB (see Hippocampal Formation) VentralCingulate=Ventral Anterior Cingulate Area,NDM.NC.AL.VACG
- Attractor Network in Hippocampus - see Reference (CT.ATTRACTOR-NETWORK)
AN=Anterior Nucleus of Thalamus,FD.TH.AN (see Cognitive Thalamus) CA1=Ventrolateral Cornu Ammonis of Hippocampus,FMM.FT.HC.CA1 (see Hippocampal Formation) CA3=Dorsomedial Cornu Ammonis of Hippocampus,FMM.FT.HC.CA3 (see Hippocampal Formation) DG=Dentate Gyrus,FMM.FT.HC.DG EC=Entorhinal Cortex,FMM.NC.PH.ET (see Rhinal Cortex) MBIN=Medial Mammillary Nucleus,FMM.FD.MB.MMB MBOUT=Lateral Mammillary Nucleus,FMM.FD.MB.LMB NACC=Accumbens Nucleus,FEC.FT.ACC (see Basal Ganglia) PERI=Perirhinal Cortex,FMM.NC.PH.PER PRESUB=Presubiculum,FMM.NC.PH.PRS SEP=Septal Nuclei,FAM.FT.SEP SUB=Subiculum,FMM.FT.HF.SUB (see Hippocampal Formation)
- Nucleus Accumbens (unknown reference) (CF.NUCLEUUS-ACCUMBENS)
CA1=Ventrolateral Cornu Ammonis of Hippocampus,FMM.FT.HC.CA1 (see Hippocampal Formation) CA3=Dorsomedial Cornu Ammonis of Hippocampus,FMM.FT.HC.CA3 (see Hippocampal Formation) EC=Entorhinal Cortex,FMM.NC.PH.ET (see Rhinal Cortex) NACC=Accumbens Nucleus,FEC.FT.ACC (see Basal Ganglia) PAS=Parasubiculum,FMM.NC.PH.PAS PRR=Perirhinal Cortex,FMM.NC.PH.PER SUB=Subiculum,FMM.FT.HF.SUB (see Hippocampal Formation)
References
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