BrainRegionNCP FD TH VPL

Ventral Posterolateral Nucleus

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This page covers biological details of component Ventral Posterolateral Nucleus. Region is part of aHuman target integrated biological model.

• Top-down path to region: Forebrain Diencephalon -> Thalamus (FD.TH) -> Sensory Thalamus (FD.TH.SR) -> Ventral Posterior Nuclei (NSA.FD.TH.VP) -> Ventral Posterolateral Nucleus (NCP.FD.TH.VPL) (see Mind Maps)
• Type: nucleus
• Quality: L0
• Brain area: Neocortical Brain - Conscious Personality Area (NCP)
• Area circuit: Body Senses Relay (CBS)
• Role: thalamic.sensory.primary
• Function: Relays somatic information from body to S1

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Components

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Component items:

• Caudal Part of Ventral Posterolateral Nucleus
• Oral Part of Ventral Posterolateral Nucleus

Connectivity

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Inbound Region Connections:

Source Area	Source Region	Source Name	Type	Reference
LPC	LPC.HL.CU	Cuneate Nucleus	excitatory-glu	(unknown reference)
	LPC.HL.GR	Gracile Nucleus	excitatory-glu	(unknown reference)
	LPC.HL.SOL	Solitary Nucleus	excitatory-glu	Amygdalar disruption of prefrontal cortex (SOL -> TH, abstract)
	LPC.SC.IZ.CCV	Central Cervical Nucleus	excitatory-glu	Thalamocortical relationships (s1P -> P, abstract)
	LPC.SC.LH.LCV	Lateral Cervical Nucleus	excitatory-glu	(unknown reference)
	LPC.SC.PH.LMG	Lower Marginal Nucleus	excitatory-glu	Afferent pain pathways (SC -> Thalamus, abstract)
	LPC.SC.PH.NP	Proprius Nucleus	excitatory-glu	Afferent pain pathways (SC -> Thalamus, abstract)
	LPC.SC.PH.UMG	Upper Marginal Nucleus	excitatory-glu	Afferent pain pathways (SC -> Thalamus, abstract)

Outbound Region Connections:

Target Area	Target Region	Target Name	Type	Reference
NCP	NCP.NC.INS.HR	Anterior Temporal Lobe	excitatory-glu	Amygdalar disruption of prefrontal cortex (TH -> INS, abstract)
	NCP.NC.PG.S1	Primary Somatosensory Cortex	excitatory-glu	Pain matrix (TH.VPL -> S1)
	NCP.NC.PG.S2	Secondary Somatosensory Cortex	excitatory-glu	Afferent pain pathways (Thalamus -> S2, abstract)
	NCP.NC.PO.PCC	Precentral Cortex	excitatory-glu	(unknown reference)

Thirdparty Circuits

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• Pain matrix - see Reference (CF.SOMATOSENSORY-THALAMUS)

INS=Posterior Insular Cortex,NCP.NC.INS.PIC
S1=Primary Somatosensory Cortex,NCP.NC.PG.S1
TH.VPI=Ventral Posteroinferior Nucleus,NCP.FD.TH.VPI
TH.VPL=Ventral Posterolateral Nucleus,NCP.FD.TH.VPL
TH.VPM=Ventral Posteromedial Nucleus,NCP.FD.TH.VPM

• Afferent pain pathways - see Reference (CF.PAIN-PATH)

ACC=Anterior Cingulate Cortex,NC.AL.ACG (see Anterior Cingulate Area)
AMY=Amygdala,FAM.FT.AM
BG=Basal Ganglia,FEC.FT.BG
Cerebellum=Cerebellar Complex,LLC.HT.CRC
Insula=Insular Cortex,NC.INS
PAG=Periaqueductal Gray Matter,LMC.MM.PAG
PB=Parabrachial Nucleus,LPC.HT.PRF.PB
PFC=Prefrontal Cortex,NC.AL.PFC
S1=Primary Somatosensory Cortex,NCP.NC.PG.S1
S2=Secondary Somatosensory Cortex,NCP.NC.PG.S2
SC=Posterior/Dorsal Horn,BMA.SC.PH
Thalamus=Sensory Thalamus,FD.TH.SR

• Amygdalar disruption of prefrontal cortex - see Reference (CF.AM-DISRUPTION)

ACG=Anterior Cingulate Cortex,NC.AL.ACG (see Anterior Cingulate Area)
AM=Amygdala,FAM.FT.AM
HC=Hippocampus,FMM.FT.HC (see Hippocampal Formation)
HT.L=Lateral Hypothalamic Area,LAC.FD.HT.LT (see Hypothalamus)
HT.PV=Paraventricular Nucleus,LAC.FD.HT.PV
INS=Insular Cortex,NC.INS
LC=Locus Coeruleus,LMC.HT.LC
MPFC=Orbitofrontal Cortex,NC.AL.OPFC (see Orbitomedial Prefrontal Cortex)
PAG=Periaqueductal Gray Matter,LMC.MM.PAG
PB=Parabrachial Nucleus,LPC.HT.PRF.PB
PUT=Endocrine Glands,TARGET.TEA.ENDOCRINE
SOL=Solitary Nucleus,LPC.HL.SOL
TH=Thalamus,FD.TH

• Thalamocortical relationships - see Reference (CL.THALAMUS-PROJECTIONS)

A=Anterior Nucleus of Thalamus,FD.TH.AN (see Cognitive Thalamus)
CM=Centromedian Nucleus of Thalamus,FEC.FD.TH.CM
LD=Lateral Dorsal Nucleus of Thalamus,FMM.FD.TH.LD
LGN=Lateral Geniculate Nucleus,NSA.FD.LGN
LP=Lateral Posterior Nucleus of Thalamus,NPE.FD.TH.LP
MD=Mediodorsal Nucleus of Thalamus,FD.TH.MD (see Cognitive Thalamus)
MGN=Medial Geniculate Body,NSA.FD.TH.MGB
P=Ventral Posterior Nuclei,NSA.FD.TH.VP (see Sensory Thalamus)
VA=Ventral Anterior Nucleus,NMA.FD.TH.VA
VL=Ventral Lateral Nucleus,NMA.FD.TH.VL
VPL=Ventral Posterolateral Nucleus,NCP.FD.TH.VPL
VPM=Ventral Posteromedial Nucleus,NCP.FD.TH.VPM
pA=Posterior Cingulate Cortex,NCP.NC.MPL.PSCG
pCM=Dorsal Putamen,FEC.FT.DPU (see Basal Ganglia)
pLD=Anterior Cingulate Cortex,NC.AL.ACG (see Anterior Cingulate Area)
pLGN=Primary Visual Cortex,NSA.NC.OCC.V1
pLP=Superior Parietal Lobule,NC.SPL
pMD=Prefrontal Cortex,NC.AL.PFC
pMGN=Primary Auditory Cortex,NSA.NC.TTG.A1
pP=Insular Cortex,NC.INS
pVA=Supplementary Motor Cortex,NMA.NC.SMC
pVL=Motor Cortex,NMA.NC.MC
pVPL=Primary Somatosensory Cortex,NCP.NC.PG.S1
pVPM=Precentral Cortex,NCP.NC.PO.PCC
s1A=Subiculum,FMM.FT.HF.SUB (see Hippocampal Formation)
s1MD=Septal Nuclei,FAM.FT.SEP
s1P=Central Cervical Nucleus,LPC.SC.IZ.CCV
s1VL=Dentate Nucleus,LLC.HT.CR.DN
s2A=Mammillary Body,FD.MB (see Hypothalamus)
s2MD=Piriform Cortex,NSA.NC.PH.PIR
s2P=Principal Trigeminal Nucleus,LPC.HT.PN.PTR
s2VL=Basal Ganglia,FEC.FT.BG
s3MD=Prefrontal Cortex,NC.AL.PFC
sCM=Globus Pallidus Internal,FEC.FT.GPI (see Basal Ganglia)
sLD=Superior Parietal Lobule,NC.SPL
sLP=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon)
sVA=Basal Ganglia,FEC.FT.BG
sVPL=Marginal Nucleus,LPC.SC.PH.MG (see Posterior/Dorsal Horn)
sVPM=Solitary Nucleus,LPC.HL.SOL

References

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• http://users.atw.hu/blp6/BLP6/HTML/C0079780323045827.htm
• http://www.nature.com/nrn/journal/v14/n7/fig_tab/nrn3516_F2.html
• http://neuropolitics.org/defaultmay10.asp
• http://what-when-how.com/neuroscience/the-thalamus-and-cerebral-cortex-integrative-systems-part-2/