BrainRegionNPE NC IPS LIP

Lateral Intraparietal Sulcus

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This page covers biological details of component Lateral Intraparietal Sulcus. Region is part of aHuman target integrated biological model.

• Top-down path to region: Cerebral Cortex -> Parietal Lobe (NC.LOBE.PAR) -> Intraparietal Sulcus (NSA.NC.IPS) -> Posterior Eye Field (NPE.NC.IPS.PEF) -> Lateral Intraparietal Sulcus (NPE.NC.IPS.LIP) (see Mind Maps)
• Type: cortex
• Quality: L0
• Brain area: Neocortical Brain - Unimodal Execution Area (NPE)
• Area circuit: Orienting by Visual Stimuli (ORV)
• Brodmann ID: 39
• Role: cortex.generic
• Function: Representing saliency of spatial locations, and attention to locations
• Notes to function:
  • Targeting eye movements

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Components

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• no child items defined

Connectivity

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Inbound Region Connections:

Source Area	Source Region	Source Name	Type	Reference
NPE	NPE.NC.OCC.V3D	Dorsal Associative Visual Cortex	feedforward-glu	Primate Control of Grasping (VC -> PIP, abstract)
NSA	NSA.NC.OCC.MT	Middle Temporal Area	feedforward-glu	Paths from Retina to Parietal Cortex and IT (MT -> LIP)
	NSA.NC.OCC.PO	Parietooccipital Area	feedforward-glu	Parietal Association Cortex (V6 -> LIP)

Outbound Region Connections:

Target Area	Target Region	Target Name	Type	Reference
LRC	LRC.MM.CJ	Cajal Nucleus	excitatory-glu	Vision Components (VAC -> SOA, abstract)
	LRC.MM.RIMLF	Rostral Interstitial Nucleus of MLF	excitatory-glu	Vision Components (VAC -> SOA, abstract)
	LRC.MM.SC.SUP	Superficial Superior Colliculus	excitatory-glu	Summary of eye movement control (PEF -> SC, abstract)
NCP	NCP.NC.MPL.PSCG	Posterior Cingulate Cortex	feedforward-glu	(unknown reference)
NDM	NDM.NC.AL.DLPFCR	Rostral Mid-Dorsolateral Prefrontal Cortex	feedforward-glu	Summary of eye movement control (PEF -> DLPFC, abstract)
NMA	NMA.NC.PMC.F7	Dorsal Rostral Premotor Cortex	feedforward-glu	Global visual system (ParietalCortex -> FrontalCortex, abstract)
NPE	NPE.NC.PMC.CFEF	Caudal Frontal Eye Field	feedforward-glu	Summary of eye movement control (PEF -> FEF, abstract)
	NPE.NC.SPL.PG	Caudal Precuneus	feedforward-glu	Paths from Retina to Parietal Cortex and IT (LIP -> 7a)
NSA	NSA.NC.IPS.AIP	Anterior Intraparietal Sulcus	feedforward-glu	Primate Control of Grasping (PIP -> AIP, abstract)

Thirdparty Circuits

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• Vision Components - see Reference (CP.VISION-COMPONENTS)

CG=Ciliary Ganglion,LAC.PN.PSYM.CLG
EWN=Edinger-Westphal Nucleus,LAC.MM.EWN
EYE=Eye,TARGET.TSA.EYE
LGN=Lateral Geniculate Nucleus,NSA.FD.LGN
OCN=Oculomotor Nucleus,LPC.MM.OCN
RT=Retinal Ganglion,LPC.PN.SG.RT
SOA=Supraoculomotor Area,VBA.MM.SOA (see Reflexes Nuclei of Midbrain Mesencephalon)
STN=Spinal Trigeminal Nucleus,LPC.HL.TGS.STR
VAC=Posterior Eye Field,NPE.NC.IPS.PEF (see Intraparietal Sulcus)
VC=Occipital Lobe,NC.LOBE.OCC

• Paths from Retina to Parietal Cortex and IT - see Reference (CP.PRIMARY-VISUAL-FORWARD-FLOWS)

7a=Caudal Precuneus,NPE.NC.SPL.PG
LGN=Lateral Geniculate Nucleus,NSA.FD.LGN
LIP=Lateral Intraparietal Sulcus,NPE.NC.IPS.LIP
MST=Medial Superior Temporal Area,NPE.NC.IPL.MST
MT=Middle Temporal Area,NSA.NC.OCC.MT
PO=Parietooccipital Area,NSA.NC.OCC.PO
Retina=Retinal Nucleus,LPC.FD.RT
TE=Inferotemporal Cortex,NSA.NC.IT.TE
TEO=Preoccipital Inferotemporal Area,NSA.NC.IT.TEO
V1=Primary Visual Cortex,NSA.NC.OCC.V1
V2=Secondary Visual Cortex,NSA.NC.OCC.V2 (see Occipital Lobe)
V3=Associative Visual Cortex,NPE.NC.OCC.V3 (see Occipital Lobe)
V4=Fusiform Gyrus,NSA.NC.OCC.V4 (see Occipital Lobe)
VIP=Ventral Intraparietal Sulcus,NSA.NC.IPS.VIP

• Global visual system - see Reference (CP.GLOBAL-VISUAL-SYSTEM)

ATH=Anterior Nucleus of Thalamus,FD.TH.AN (see Cognitive Thalamus)
BGA=Basal Ganglia,FEC.FT.BG
FrontalCortex=Anterior Lobe,NC.LOBE.ANT
LGN=Lateral Geniculate Nucleus,NSA.FD.LGN
OPN=Oculomotor Nucleus,LPC.MM.OCN
ParietalCortex=Parietal Lobe,NC.LOBE.PAR
Pulvinar=Pulvinar,FD.PV (see Sensory Thalamus)
RF=Pontine Reticular Formation,HT.RF
Retina=Retinal Nucleus,LPC.FD.RT
SCi=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon)
SCs=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon)
SNc=Substantia Nigra Pars Compacta Lateral,FEC.FT.SNC.LT
SNr=Substantia Nigra Pars Reticulata Dorsolateral,FEC.FT.SNR.DL
SpinalCord=Lamina IX,SC.VH.L9 (see Anterior/Ventral Horn)
Striatum=Striatum,FEC.FT.ST (see Basal Ganglia)
VisualCortex=Occipital Lobe,NC.LOBE.OCC

• Summary of eye movement control - see Reference (CP.EYE-FIELDS)

DLPFC=Mid-Dorsolateral Prefrontal Cortex,NDM.NC.AL.DLPFC (see Lateral Prefrontal Cortex)
FEF=Frontal Eye Field,NMA.NC.PMC.FEF (see Premotor Cortex)
PEF=Posterior Eye Field,NPE.NC.IPS.PEF (see Intraparietal Sulcus)
PPRF=Paramedian Pontine Reticular Formation,HT.PRF.PPRF (see Pontine Reticular Formation)
SC=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon)
SEF=Supplementary Eye Field,NPE.NC.SMC.SEF
riMLF=Cajal Nucleus,LRC.MM.CJ

• Primate Control of Grasping - see Reference (CM.GRASPING-CONTROL)

46=Mid-Dorsolateral Prefrontal Cortex,NDM.NC.AL.DLPFC (see Lateral Prefrontal Cortex)
AIP=Anterior Intraparietal Sulcus,NSA.NC.IPS.AIP
BG=Basal Ganglia,FEC.FT.BG
BTH=Ventral Anterior Nucleus,NMA.FD.TH.VA
F1=Motor Cortex,NMA.NC.MC
F2=Dorsal Caudal Premotor Cortex,NMA.NC.PMC.F2
F4=Ventral Caudal Premotor Cortex,NMA.NC.PMC.F4
F5=Ventral Rostral Premotor Cortex,NMA.NC.PMC.F5
F6=Pre-Supplementary Motor Area,NMA.NC.SMC.F6
IT=Inferotemporal Area,NSA.NC.IT
PIP=Posterior Eye Field,NPE.NC.IPS.PEF (see Intraparietal Sulcus)
S1=Primary Somatosensory Cortex,NCP.NC.PG.S1
S2=Primary Somatosensory Cortex,NCP.NC.PG.S1
VC=Occipital Lobe,NC.LOBE.OCC
VIP=Ventral Intraparietal Sulcus,NSA.NC.IPS.VIP

• Parietal Association Cortex - see Reference (CP.VISUAL-PARIETAL-ASSOCIATION-CORTEX)

7a=Caudal Precuneus,NPE.NC.SPL.PG
7b=Rostral Precuneus,NPE.NC.SPL.PF
AIP=Anterior Intraparietal Sulcus,NSA.NC.IPS.AIP
LGB=Lateral Geniculate Nucleus,NSA.FD.LGN
LIP=Lateral Intraparietal Sulcus,NPE.NC.IPS.LIP
TE=Inferotemporal Cortex,NSA.NC.IT.TE
TEO=Preoccipital Inferotemporal Area,NSA.NC.IT.TEO
V1=Primary Visual Cortex,NSA.NC.OCC.V1
V2=Secondary Visual Cortex,NSA.NC.OCC.V2 (see Occipital Lobe)
V3A=Associative Visual Cortex,NPE.NC.OCC.V3 (see Occipital Lobe)
V3d=Associative Visual Cortex,NPE.NC.OCC.V3 (see Occipital Lobe)
V3v=Associative Visual Cortex,NPE.NC.OCC.V3 (see Occipital Lobe)
V4=Fusiform Gyrus,NSA.NC.OCC.V4 (see Occipital Lobe)
V5=Middle Temporal Area,NSA.NC.OCC.MT
V5A=Middle Temporal Area,NSA.NC.OCC.MT
V6=Parietooccipital Area,NSA.NC.OCC.PO
VIP=Ventral Intraparietal Sulcus,NSA.NC.IPS.VIP
cIPS=Posterior Eye Field,NPE.NC.IPS.PEF (see Intraparietal Sulcus)

• Saccadic Vision - see Reference (CP.SACCADIC-VISION)

BG=Basal Ganglia,FEC.FT.BG
CN=Caudate Nucleus,FEC.FT.CN (see Basal Ganglia)
CR=Cerebellum,LLC.HT.CR (see Cerebellar Complex)
FrontalCortex=Anterior Lobe,NC.LOBE.ANT
GPe=Globus Pallidus External,FEC.FT.GPE (see Basal Ganglia)
LGN=Lateral Geniculate Nucleus,NSA.FD.LGN
LIP=Lateral Intraparietal Sulcus,NPE.NC.IPS.LIP
RF=Pontine Reticular Formation,HT.RF
Retina=Retinal Nucleus,LPC.FD.RT
SCi=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon)
SCs=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon)
SNpr=Substantia Nigra Pars Reticulata Dorsolateral,FEC.FT.SNR.DL
STN=Subthalamic Nucleus,FEC.FD.STN (see Subthalamus Area)
Thalamus=Thalamus,FD.TH
VisualCortex=Occipital Lobe,NC.LOBE.OCC

• Oculomotor decision-making - see Reference (CP.OCULOMOTOR-DECISION-MAKING)

AMYG=Amygdala,FAM.FT.AM
CGa=Anterior Cingulate Cortex,NC.AL.ACG (see Anterior Cingulate Area)
CGp=Posterior Cingulate Cortex,NCP.NC.MPL.PSCG
Caudate=Caudate Nucleus,FEC.FT.CN (see Basal Ganglia)
FEF=Frontal Eye Field,NMA.NC.PMC.FEF (see Premotor Cortex)
LIP=Lateral Intraparietal Sulcus,NPE.NC.IPS.LIP
NAC=Accumbens Nucleus,FEC.FT.ACC (see Basal Ganglia)
OFC=Orbitofrontal Cortex,NC.AL.OPFC (see Orbitomedial Prefrontal Cortex)
PFC=Mid-Dorsolateral Prefrontal Cortex,NDM.NC.AL.DLPFC (see Lateral Prefrontal Cortex)
SC=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon)
SEF=Supplementary Eye Field,NPE.NC.SMC.SEF
SNc=Substantia Nigra Pars Compacta Lateral,FEC.FT.SNC.LT
SNr=Substantia Nigra Pars Reticulata Dorsolateral,FEC.FT.SNR.DL
Thalamus=Thalamus,FD.TH
VTA=Ventral Tegmental Area,LMC.MM.VTA

References

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• http://neuroscience.uth.tmc.edu/s3/chapter07.html
• http://thebrain.mcgill.ca/flash/i/i_02/i_02_cr/i_02_cr_vis/i_02_cr_vis.html
• http://www.sciencedirect.com/science/article/pii/S0959438808001566
• http://www.cixip.com/index.php/page/content/id/1190
• http://www.sciencedirect.com/science/article/pii/S0893608098000471
• http://www.sciencedirect.com/science/article/pii/S0166223697010679
• http://www.nature.com/nrn/journal/v5/n3/box/nrn1345_BX1.html
• http://www.springerimages.com/Images/LifeSciences/1-10.1007_s00359-004-0565-9-0