BrainRegionLAC FD HT MPO
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Median Preoptic Nucleus
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This page covers biological details of component Median Preoptic Nucleus. Region is part of aHuman target integrated biological model.
- Top-down path to region: Forebrain Diencephalon -> Hypothalamus (FD.HT) -> Anterior Hypothalamus Area (LAC.FD.HT.AHT) -> Chiasmatic Area (LAC.FD.HT.CHS) -> Preoptic Nucleus (LAC.FD.HT.PO) -> Median Preoptic Nucleus (LAC.FD.HT.MPO) (see Mind Maps)
- Type: nucleus
- Quality: L0
- Brain area: Lower Brain - Autonomous Control Area (LAC)
- Area circuit: Autonomic Thermoregulation (LAT)
- Role: processor.autonomic
- Function: generates thirst
- Notes to function:
- Drinking decreases noradrenaline release in median preoptic nucleus
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Components
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- no child items defined
Connectivity
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Inbound Region Connections:
| Source Area | Source Region | Source Name | Type | Reference |
| FAM | FAM.FT.AM.MPD | Medial Posterior Dorsal Amygdaloid Nucleus | inhibitory-gaba | Role for serotonin in moral behavior (AMY -> HYP, abstract) |
| FMM | FMM.FT.HC.CA1D | Distal CA1 of Hippocampus | excitatory-glu | Feeling (HC -> HT, abstract) |
| LAC | LAC.FD.HT.DM | Dorsomedial Hypothalamic Nucleus | excitatory-glu | Eating and sleeping to survive (DMH -> MPO) |
| LAC.FD.HT.PRM | Premammillary Nucleus | excitatory-glu | (unknown reference) | |
| LAC.FD.HT.SCN | Suprachiasmatic Nucleus | excitatory-glu | Intrahypothalamic connections important for neural control of food intake and energy balance (SCH -> MPOA) | |
| LAC.HL.TGS.PE5 | Peritrigeminal Nucleus | excitatory-glu | (unknown reference) | |
| NDM | NDM.FD.TH.PV | Paraventricular Nucleus of Thalamus | excitatory-glu | (unknown reference) |
Outbound Region Connections:
| Target Area | Target Region | Target Name | Type | Reference |
| FAM | FAM.FD.TH.PT | Paratenial Nucleus of Thalamus | excitatory-glu | (unknown reference) |
| LAC | LAC.FD.HT.AH | Anterior Hypothalamic Nucleus | excitatory-glu | Intrahypothalamic connections important for neural control of food intake and energy balance (MPOA -> AH) |
| LAC.FD.HT.PV | Paraventricular Nucleus | excitatory-glu | Intrahypothalamic connections important for neural control of food intake and energy balance (MPOA -> PA) | |
| LAC.FD.HT.SO | Supraoptic Nucleus | excitatory-glu | Intrahypothalamic connections important for neural control of food intake and energy balance (MPOA -> SON) | |
| LMC | LMC.HL.RP.OB | Raphe Obscurus Nucleus | excitatory-glu | (unknown reference) |
Thirdparty Circuits
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- Intrahypothalamic connections important for neural control of food intake and energy balance - see Reference (CL.INTRAHYPOTHALAMIC)
AH=Anterior Hypothalamic Nucleus,LAC.FD.HT.AH ARC=Arcuate Nucleus of Hypothalamus,LAC.FD.HT.AR DMN=Dorsomedial Hypothalamic Nucleus,LAC.FD.HT.DM LHA=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN MPOA=Median Preoptic Nucleus,LAC.FD.HT.MPO PA=Paraventricular Nucleus,LAC.FD.HT.PV SCH=Suprachiasmatic Nucleus,LAC.FD.HT.SCN SON=Supraoptic Nucleus,LAC.FD.HT.SO VMN=Ventromedial Hypothalamic Nucleus,LAC.FD.HT.VM
- Eating and sleeping to survive - see Reference (CP.DMH-CYCLES)
ARC=Arcuate Nucleus of Hypothalamus,LAC.FD.HT.AR DMH=Dorsomedial Hypothalamic Nucleus,LAC.FD.HT.DM LHA=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN MPO=Median Preoptic Nucleus,LAC.FD.HT.MPO PVH=Paraventricular Nucleus,LAC.FD.HT.PV SCN=Suprachiasmatic Nucleus,LAC.FD.HT.SCN VLPO=Ventrolateral Preoptic Nucleus,LAC.FD.HT.VLPO VMH=Ventromedial Hypothalamic Nucleus,LAC.FD.HT.VM
- Physiology and pathophysiology of lower urinary tract - see Reference (CM.ONUF)
CN=Caudate Nucleus,FEC.FT.CN (see Basal Ganglia) DVM=Vagus Nucleus,LAC.HL.VGN IMG=Inferior Mesenteric Ganglion,LAC.PN.SYM.IMG IML=Intermediolateral Nucleus,LAC.SC.IZ.IML LC=Locus Coeruleus,LMC.HT.LC MPFC=Orbitofrontal Cortex,NC.AL.OPFC (see Orbitomedial Prefrontal Cortex) MPOA=Median Preoptic Nucleus,LAC.FD.HT.MPO NBM=Basal Nucleus of Meynert,LMC.FT.NBM ONF=Onuf's Nucleus,LPC.SC.VH.ONF PBN=Parabrachial Nucleus,LPC.HT.PRF.PB PEL=Pelvic Peripheral Ganglion,LAC.PN.PSYM.PPG PU=Dorsal Putamen Lateral,FEC.FT.PU.LT PVN=Paraventricular Nucleus,LAC.FD.HT.PV SNC=Substantia Nigra Pars Compacta Lateral,FEC.FT.SNC.LT SPS=Sacral Parasympathetic Nucleus,LAC.SC.IZ.SPS VTA=Ventral Tegmental Area,LMC.MM.VTA ZI=Subthalamic Nucleus Caudal,BGA.FD.STN.ZI
References
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- http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.122.2314rep=rep1type=pdf
- http://www.dana.org/Publications/ReportDetails.aspx?id=44217
- http://www.intechopen.com/books/computational-intelligence-in-electromyography-analysis-a-perspective-on-current-applications-and-future-challenges/sphincter-emg-for-diagnosing-multiple-system-atrophy-and-related-disorders
