Difference between revisions of "BrainRegionLMC HT TG LDT"

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* '''Top-down path to region''': Hindbrain Metencephalon -> [[BrainCenterHT_TG|Pontine Tegmental Nuclei]] (HT.TG) -> [[BrainRegionLMC_HT_TG_LDT|Laterodorsal Tegmental Nucleus]] (LMC.HT.TG.LDT) (see [[OverallMindMaps|Mind Maps]])
 
* '''Top-down path to region''': Hindbrain Metencephalon -> [[BrainCenterHT_TG|Pontine Tegmental Nuclei]] (HT.TG) -> [[BrainRegionLMC_HT_TG_LDT|Laterodorsal Tegmental Nucleus]] (LMC.HT.TG.LDT) (see [[OverallMindMaps|Mind Maps]])
 
* '''Type''': nucleus
 
* '''Type''': nucleus
* '''Brain area''': [[BrainAreaLMC|Lower Brain - Modulatory Contol Area]]
+
* '''Quality''': L0
 +
* '''Brain area''': [[BrainAreaLMC|Lower Brain - Modulatory Contol Area]] (LMC)
 +
* '''Area circuit''': Acetylcholine - PNS Actions and CNS plasticity, arousal and reward (ACH)
 
* '''Role''': processor.autonomic
 
* '''Role''': processor.autonomic
 
* '''Function''': Modulating sustained attention or in mediating alerting responses
 
* '''Function''': Modulating sustained attention or in mediating alerting responses
* '''Notes to function''': sleep, waking, motor function, learning and reward
+
* '''Notes to function''':  
 +
** sleep, waking, motor function, learning and reward
 
(generated)
 
(generated)
 
= Components =
 
= Components =
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{| class=wikitable width=80%
 
{| class=wikitable width=80%
| '''Source Area''' || '''Source Region''' || '''Source Name''' || '''Type''' || '''Reference'''
+
| '''Source Area''' || '''Source Region''' || '''Source Name''' || '''Type''' || '''Role''' || '''Reference'''
 
|-
 
|-
| [[BrainAreaFAM|FAM]] || [[BrainRegionFAM_FD_LHB_MED|FAM.FD.LHB.MED]] || Lateral Habenula Medial Part || excitatory-glu || [http://journal.frontiersin.org/article/10.3389/fnhum.2013.00826/full Regulation of the rapid eye movement (REM) sleep by habenular projection (LHbM -> DTG)]
+
| [[BrainAreaFAM|FAM]] || [[BrainRegionFAM_FD_LHB_MED|FAM.FD.LHB.MED]] || Lateral Habenula Medial Part || excitatory-glu || uncertain ||[http://journal.frontiersin.org/article/10.3389/fnhum.2013.00826/full Regulation of the rapid eye movement (REM) sleep by habenular projection (LHbM -> DTG)]
 
|-
 
|-
| [[BrainAreaFEC|FEC]] || [[BrainRegionFEC_HT_TG_IPD|FEC.HT.TG.IPD]] || Interpeduncular Nucleus || modulatory-ach || [http://www.scholarpedia.org/article/Head_direction_cells Head Direction Cell Circuit (IPD -> DTN)]
+
| [[BrainAreaFEC|FEC]] || [[BrainRegionFEC_HT_TG_IPD|FEC.HT.TG.IPD]] || Interpeduncular Nucleus || modulatory-ach || uncertain ||[http://www.scholarpedia.org/article/Head_direction_cells Head Direction Cell Circuit (IPD -> DTN)]
 
|-
 
|-
|  || [[BrainRegionFEC_HT_TG_RMTG|FEC.HT.TG.RMTG]] || Rostromedial Tegmental Nucleus || inhibitory-gaba || (unknown reference)
+
|  || [[BrainRegionFEC_HT_TG_RMTG|FEC.HT.TG.RMTG]] || Rostromedial Tegmental Nucleus || inhibitory-gaba || uncertain ||(unknown reference)
 
|-
 
|-
| [[BrainAreaFMM|FMM]] || [[BrainRegionFMM_FD_MB_LMB|FMM.FD.MB.LMB]] || Lateral Mammillary Nucleus || excitatory-glu || [http://www.scholarpedia.org/article/Head_direction_cells Head Direction Cell Circuit (LMB -> DTN)]
+
| [[BrainAreaFMM|FMM]] || [[BrainRegionFMM_FD_MB_LMB|FMM.FD.MB.LMB]] || Lateral Mammillary Nucleus || excitatory-glu || uncertain ||[http://www.scholarpedia.org/article/Head_direction_cells Head Direction Cell Circuit (LMB -> DTN)]
 
|-
 
|-
| [[BrainAreaLAC|LAC]] || [[BrainRegionLAC_FD_HT_VLPO|LAC.FD.HT.VLPO]] || Ventrolateral Preoptic Nucleus || excitatory-glu || [http://www.nature.com/neuro/journal/v5/n10/fig_tab/nn913_F1.html Simplified NREM sleep-promoting pathway (VLPO -> LDTg)]
+
| [[BrainAreaLAC|LAC]] || [[BrainRegionLAC_FD_HT_VLPO|LAC.FD.HT.VLPO]] || Ventrolateral Preoptic Nucleus || excitatory-glu || uncertain ||[http://www.nature.com/neuro/journal/v5/n10/fig_tab/nn913_F1.html Simplified NREM sleep-promoting pathway (VLPO -> LDTg)]
 
|-
 
|-
| [[BrainAreaLRC|LRC]] || [[BrainRegionLRC_HL_NPH|LRC.HL.NPH]] || Prepositus Nucleus || excitatory-glu || (unknown reference)
+
| [[BrainAreaLRC|LRC]] || [[BrainRegionLRC_HL_NPH|LRC.HL.NPH]] || Prepositus Nucleus || excitatory-glu || uncertain ||(unknown reference)
 
|-
 
|-
| [[BrainAreaNSA|NSA]] || [[BrainRegionNSA_FD_TH_SG|NSA.FD.TH.SG]] || Suprageniculate Nucleus of Thalamus || excitatory-glu || (unknown reference)
+
| [[BrainAreaNSA|NSA]] || [[BrainRegionNSA_FD_TH_SG|NSA.FD.TH.SG]] || Suprageniculate Nucleus of Thalamus || excitatory-glu || uncertain ||(unknown reference)
 
|}
 
|}
  
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{| class=wikitable width=80%
 
{| class=wikitable width=80%
| '''Target Area''' || '''Target Region''' || '''Target Name''' || '''Type''' || '''Reference'''
+
| '''Target Area''' || '''Target Region''' || '''Target Name''' || '''Type''' || '''Role''' || '''Reference'''
 
|-
 
|-
| [[BrainAreaFEC|FEC]] || [[BrainRegionFEC_HT_TG_IPD|FEC.HT.TG.IPD]] || Interpeduncular Nucleus || modulatory-ach || (unknown reference)
+
| [[BrainAreaFEC|FEC]] || [[BrainRegionFEC_HT_TG_IPD|FEC.HT.TG.IPD]] || Interpeduncular Nucleus || modulatory-ach || uncertain || (unknown reference)
 
|-
 
|-
| [[BrainAreaFMM|FMM]] || [[BrainRegionFMM_FD_MB_LMB|FMM.FD.MB.LMB]] || Lateral Mammillary Nucleus || modulatory-ach || [http://ahuman.org/svn/ahengine/research/articles/2009-Hippocampus-Thesis.pdf Hippocampal Formation (DTN -> LMam)]
+
| [[BrainAreaFMM|FMM]] || [[BrainRegionFMM_FD_MB_LMB|FMM.FD.MB.LMB]] || Lateral Mammillary Nucleus || modulatory-ach || uncertain || [http://ahuman.org/svn/ahengine/research/articles/2009-Hippocampus-Thesis.pdf Hippocampal Formation (DTN -> LMam)]
 
|-
 
|-
| [[BrainAreaLAC|LAC]] || [[BrainRegionLAC_HL_SAL_ISL|LAC.HL.SAL.ISL]] || Inferior Salivatory Nucleus || modulatory-ach || (unknown reference)
+
| [[BrainAreaLAC|LAC]] || [[BrainRegionLAC_HL_SAL_ISL|LAC.HL.SAL.ISL]] || Inferior Salivatory Nucleus || modulatory-ach || uncertain || (unknown reference)
 
|-
 
|-
|  || [[BrainRegionLAC_HL_SAL_SSL|LAC.HL.SAL.SSL]] || Superior Salivatory Nucleus || modulatory-ach || (unknown reference)
+
|  || [[BrainRegionLAC_HL_SAL_SSL|LAC.HL.SAL.SSL]] || Superior Salivatory Nucleus || modulatory-ach || uncertain || (unknown reference)
 
|-
 
|-
| [[BrainAreaLRC|LRC]] || [[BrainRegionLRC_HL_NPH|LRC.HL.NPH]] || Prepositus Nucleus || modulatory-ach || [http://www.scholarpedia.org/article/Head_direction_cells Head Direction Cell Circuit (DTN -> NPRP)]
+
| [[BrainAreaLRC|LRC]] || [[BrainRegionLRC_HL_NPH|LRC.HL.NPH]] || Prepositus Nucleus || modulatory-ach || uncertain || [http://www.scholarpedia.org/article/Head_direction_cells Head Direction Cell Circuit (DTN -> NPRP)]
 
|-
 
|-
| [[BrainAreaNSA|NSA]] || [[BrainRegionNSA_FD_TH_SG|NSA.FD.TH.SG]] || Suprageniculate Nucleus of Thalamus || modulatory-ach || [http://www.scholarpedia.org/article/Head_direction_cells Head Direction Cell Circuit (DTN -> SUPGEN)]
+
| [[BrainAreaNSA|NSA]] || [[BrainRegionNSA_FD_TH_SG|NSA.FD.TH.SG]] || Suprageniculate Nucleus of Thalamus || modulatory-ach || uncertain || [http://www.scholarpedia.org/article/Head_direction_cells Head Direction Cell Circuit (DTN -> SUPGEN)]
 
|}
 
|}
  

Latest revision as of 18:29, 28 April 2019

Laterodorsal Tegmental Nucleus

@@Home -> BiologicalLifeResearch -> BrainAreaLMC -> BrainRegionLMC_HT_TG_LDT


This page covers biological details of component Laterodorsal Tegmental Nucleus. Region is part of aHuman target integrated biological model.

  • Top-down path to region: Hindbrain Metencephalon -> Pontine Tegmental Nuclei (HT.TG) -> Laterodorsal Tegmental Nucleus (LMC.HT.TG.LDT) (see Mind Maps)
  • Type: nucleus
  • Quality: L0
  • Brain area: Lower Brain - Modulatory Contol Area (LMC)
  • Area circuit: Acetylcholine - PNS Actions and CNS plasticity, arousal and reward (ACH)
  • Role: processor.autonomic
  • Function: Modulating sustained attention or in mediating alerting responses
  • Notes to function:
    • sleep, waking, motor function, learning and reward

(generated)

Components

(generated)


Component items:

  • Lateral Tegmental Nucleus
  • Dorsal Tegmental Nucleus (LMC.HT.TG.DTG): accurate landmark navigation
    • Dorsal Tegmental Nucleus Pars Dorsalis
    • Dorsal Tegmental Nucleus Pars Ventralis

Connectivity

(generated)


LMC.HT.TG.LDT.dot.png

Inbound Region Connections:

Source Area Source Region Source Name Type Role Reference
FAM FAM.FD.LHB.MED Lateral Habenula Medial Part excitatory-glu uncertain Regulation of the rapid eye movement (REM) sleep by habenular projection (LHbM -> DTG)
FEC FEC.HT.TG.IPD Interpeduncular Nucleus modulatory-ach uncertain Head Direction Cell Circuit (IPD -> DTN)
FEC.HT.TG.RMTG Rostromedial Tegmental Nucleus inhibitory-gaba uncertain (unknown reference)
FMM FMM.FD.MB.LMB Lateral Mammillary Nucleus excitatory-glu uncertain Head Direction Cell Circuit (LMB -> DTN)
LAC LAC.FD.HT.VLPO Ventrolateral Preoptic Nucleus excitatory-glu uncertain Simplified NREM sleep-promoting pathway (VLPO -> LDTg)
LRC LRC.HL.NPH Prepositus Nucleus excitatory-glu uncertain (unknown reference)
NSA NSA.FD.TH.SG Suprageniculate Nucleus of Thalamus excitatory-glu uncertain (unknown reference)

Outbound Region Connections:

Target Area Target Region Target Name Type Role Reference
FEC FEC.HT.TG.IPD Interpeduncular Nucleus modulatory-ach uncertain (unknown reference)
FMM FMM.FD.MB.LMB Lateral Mammillary Nucleus modulatory-ach uncertain Hippocampal Formation (DTN -> LMam)
LAC LAC.HL.SAL.ISL Inferior Salivatory Nucleus modulatory-ach uncertain (unknown reference)
LAC.HL.SAL.SSL Superior Salivatory Nucleus modulatory-ach uncertain (unknown reference)
LRC LRC.HL.NPH Prepositus Nucleus modulatory-ach uncertain Head Direction Cell Circuit (DTN -> NPRP)
NSA NSA.FD.TH.SG Suprageniculate Nucleus of Thalamus modulatory-ach uncertain Head Direction Cell Circuit (DTN -> SUPGEN)

Thirdparty Circuits

(generated)

ATN=Anterior Nucleus of Thalamus,FD.TH.AN (see Cognitive Thalamus)
CA1=Ventrolateral Cornu Ammonis of Hippocampus,FMM.FT.HC.CA1 (see Hippocampal Formation)
CA3=Dorsomedial Cornu Ammonis of Hippocampus,FMM.FT.HC.CA3 (see Hippocampal Formation)
DG=Dentate Gyrus,FMM.FT.HC.DG
DTN=Laterodorsal Tegmental Nucleus,LMC.HT.TG.LDT
EC=Entorhinal Cortex,FMM.NC.PH.ET (see Rhinal Cortex)
LDN=Lateral Dorsal Nucleus of Thalamus,FMM.FD.TH.LD
LMam=Lateral Mammillary Nucleus,FMM.FD.MB.LMB
PoS=Postsubiculum,FMM.NC.PH.POS
Rsp=Retrosplenial Cortex,NCP.NC.MPL.RSC
Sub=Subiculum,FMM.FT.HF.SUB (see Hippocampal Formation)

AD=Anterodorsal Nucleus,FMM.FD.TH.AD
DTN=Laterodorsal Tegmental Nucleus,LMC.HT.TG.DTG
EC=Entorhinal Cortex,FMM.NC.PH.ET (see Rhinal Cortex)
HC=Hippocampus,FMM.FT.HC (see Hippocampal Formation)
IPD=Interpeduncular Nucleus,FEC.HT.TG.IPD
LD=Lateral Dorsal Nucleus of Thalamus,FMM.FD.TH.LD
LHAB=Habenula,FAM.FD.HB
LMB=Lateral Mammillary Nucleus,FMM.FD.MB.LMB
MVSN=Medial Vestibular Nucleus,LPC.HT.MVBN
NPRP=Prepositus Nucleus,LRC.HL.NPH
PC=Parietal Lobe,NC.LOBE.PAR
PRHC=Postrhinal Cortex,FMM.NC.PH.POR
PSUB=Postsubiculum,FMM.NC.PH.POS
RSP=Retrosplenial Cortex,NCP.NC.MPL.RSC
SUPGEN=Suprageniculate Nucleus of Thalamus,NSA.FD.TH.SG
VC=Occipital Lobe,NC.LOBE.OCC

DBB=Diagonal Band of Broca,FAM.FT.SEP.DBB
DTG=Laterodorsal Tegmental Nucleus,LMC.HT.TG.DTG
EPN=Endopiriform Nucleus,FAM.FT.EPF
GPi=Globus Pallidus Internal,FEC.FT.GPI (see Basal Ganglia)
LHT=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN
LHbL=Lateral Habenula Lateral Part,FAM.FD.LHB.LT
LHbM=Lateral Habenula Medial Part,FAM.FD.LHB.MED
NI=Incertus Nucleus,FAM.HT.TG.NI
RMTg=Rostromedial Tegmental Nucleus,FEC.HT.TG.RMTG
Raphe=Raphe Nuclei of Medulla,LMC.HL.RP (see Medullary Reticular Formation)
SNc=Substantia Nigra Pars Compacta,FEC.FT.SNC (see Basal Ganglia)
VTA=Ventral Tegmental Area,LMC.MM.VTA
VTG=Ventral Tegmental Area,LMC.MM.VTG

ADTH=Anterodorsal Nucleus,FMM.FD.TH.AD
AMTH=Anteromedial Nucleus,NCP.FD.TH.AM
AVTH=Anteroventral Nucleus,FMM.FD.TH.AV
DTN=Laterodorsal Tegmental Nucleus,LMC.HT.TG.LDT
LMB=Lateral Mammillary Nucleus,FMM.FD.MB.LMB
MMB=Medial Mammillary Nucleus,FMM.FD.MB.MMB
MedialEC=Entorhinal Cortex,FMM.NC.PH.ET (see Rhinal Cortex)
PAS=Parasubiculum,FMM.NC.PH.PAS
POS=Postsubiculum,FMM.NC.PH.POS
PRS=Presubiculum,FMM.NC.PH.PRS
SEP=Septal Nuclei,FAM.FT.SEP
SUB=Subiculum,FMM.FT.HF.SUB (see Hippocampal Formation)
SupraMM=Supramammillary Nucleus,LAC.FD.HT.SUM
TuberoMM=Lateral Tuberal Nuclei,LAC.FD.HT.LTUB (see Hypothalamus)
VTN=Ventral Tegmental Area,LMC.MM.VTA

LC=Locus Coeruleus,LMC.HT.LC
LDTg=Laterodorsal Tegmental Nucleus,LMC.HT.TG.LDT
TMN=Tuberomammillary Nucleus,LAC.FD.HT.TBM
VLPO=Ventrolateral Preoptic Nucleus,LAC.FD.HT.VLPO


References

(generated)