Difference between revisions of "BrainRegionLMC HT TG LDT"

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<pre style="color: green">Laterodorsal Tegmental Nucleus</pre>
 
<pre style="color: green">Laterodorsal Tegmental Nucleus</pre>
 
@@[[Home]] -> [[BiologicalLifeResearch]] -> [[BrainAreaLMC]] -> [[BrainRegionLMC_HT_TG_LDT]]
 
@@[[Home]] -> [[BiologicalLifeResearch]] -> [[BrainAreaLMC]] -> [[BrainRegionLMC_HT_TG_LDT]]
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* '''Top-down path to region''': Hindbrain Metencephalon -> [[BrainCenterHT_TG|Pontine Tegmental Nuclei]] (HT.TG) -> [[BrainRegionLMC_HT_TG_LDT|Laterodorsal Tegmental Nucleus]] (LMC.HT.TG.LDT) (see [[OverallMindMaps|Mind Maps]])
 
* '''Top-down path to region''': Hindbrain Metencephalon -> [[BrainCenterHT_TG|Pontine Tegmental Nuclei]] (HT.TG) -> [[BrainRegionLMC_HT_TG_LDT|Laterodorsal Tegmental Nucleus]] (LMC.HT.TG.LDT) (see [[OverallMindMaps|Mind Maps]])
 
* '''Type''': nucleus
 
* '''Type''': nucleus
* '''Brain area''': [[BrainAreaLMC|Lower Brain - Modulatory Contol Area]]
+
* '''Quality''': L0
 +
* '''Brain area''': [[BrainAreaLMC|Lower Brain - Modulatory Contol Area]] (LMC)
 +
* '''Area circuit''': Acetylcholine - PNS Actions and CNS plasticity, arousal and reward (ACH)
 
* '''Role''': processor.autonomic
 
* '''Role''': processor.autonomic
 
* '''Function''': Modulating sustained attention or in mediating alerting responses
 
* '''Function''': Modulating sustained attention or in mediating alerting responses
* '''Notes to function''': sleep, waking, motor function, learning and reward
+
* '''Notes to function''':  
 +
** sleep, waking, motor function, learning and reward
 
(generated)
 
(generated)
 
= Components =
 
= Components =
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{| class=wikitable width=80%
 
{| class=wikitable width=80%
| '''Source Area''' || '''Source Region''' || '''Source Name''' || '''Type''' || '''Reference'''
+
| '''Source Area''' || '''Source Region''' || '''Source Name''' || '''Type''' || '''Role''' || '''Reference'''
 
|-
 
|-
| [[BrainAreaFAM|FAM]] || [[BrainRegionFAM_FD_LHB_MED|FAM.FD.LHB.MED]] || Lateral Habenula Medial Part || excitatory-glu || [http://journal.frontiersin.org/article/10.3389/fnhum.2013.00826/full Regulation of the rapid eye movement (REM) sleep by habenular projection (LHbM -> DTG)]
+
| [[BrainAreaFAM|FAM]] || [[BrainRegionFAM_FD_LHB_MED|FAM.FD.LHB.MED]] || Lateral Habenula Medial Part || excitatory-glu || uncertain ||[http://journal.frontiersin.org/article/10.3389/fnhum.2013.00826/full Regulation of the rapid eye movement (REM) sleep by habenular projection (LHbM -> DTG)]
 
|-
 
|-
| [[BrainAreaFEC|FEC]] || [[BrainRegionFEC_HT_TG_IPD|FEC.HT.TG.IPD]] || Interpeduncular Nucleus || modulatory-ach || [http://www.scholarpedia.org/article/Head_direction_cells Head Direction Cell Circuit (IPD -> DTN)]
+
| [[BrainAreaFEC|FEC]] || [[BrainRegionFEC_HT_TG_IPD|FEC.HT.TG.IPD]] || Interpeduncular Nucleus || modulatory-ach || uncertain ||[http://www.scholarpedia.org/article/Head_direction_cells Head Direction Cell Circuit (IPD -> DTN)]
 
|-
 
|-
|  || [[BrainRegionFEC_HT_TG_RMTG|FEC.HT.TG.RMTG]] || Rostromedial Tegmental Nucleus || inhibitory-gaba || (unknown reference)
+
|  || [[BrainRegionFEC_HT_TG_RMTG|FEC.HT.TG.RMTG]] || Rostromedial Tegmental Nucleus || inhibitory-gaba || uncertain ||(unknown reference)
 
|-
 
|-
| [[BrainAreaFMM|FMM]] || [[BrainRegionFMM_FD_MB_LMB|FMM.FD.MB.LMB]] || Lateral Mammillary Nucleus || excitatory-glu || [http://www.scholarpedia.org/article/Head_direction_cells Head Direction Cell Circuit (LMB -> DTN)]
+
| [[BrainAreaFMM|FMM]] || [[BrainRegionFMM_FD_MB_LMB|FMM.FD.MB.LMB]] || Lateral Mammillary Nucleus || excitatory-glu || uncertain ||[http://www.scholarpedia.org/article/Head_direction_cells Head Direction Cell Circuit (LMB -> DTN)]
 
|-
 
|-
| [[BrainAreaLAC|LAC]] || [[BrainRegionLAC_FD_HT_VLPO|LAC.FD.HT.VLPO]] || Ventrolateral Preoptic Nucleus || excitatory-glu || [http://www.nature.com/neuro/journal/v5/n10/fig_tab/nn913_F1.html Simplified NREM sleep-promoting pathway (VLPO -> LDTg)]
+
| [[BrainAreaLAC|LAC]] || [[BrainRegionLAC_FD_HT_VLPO|LAC.FD.HT.VLPO]] || Ventrolateral Preoptic Nucleus || excitatory-glu || uncertain ||[http://www.nature.com/neuro/journal/v5/n10/fig_tab/nn913_F1.html Simplified NREM sleep-promoting pathway (VLPO -> LDTg)]
 
|-
 
|-
| [[BrainAreaLRC|LRC]] || [[BrainRegionLRC_HL_NPH|LRC.HL.NPH]] || Prepositus Nucleus || excitatory-glu || (unknown reference)
+
| [[BrainAreaLRC|LRC]] || [[BrainRegionLRC_HL_NPH|LRC.HL.NPH]] || Prepositus Nucleus || excitatory-glu || uncertain ||(unknown reference)
 
|-
 
|-
| [[BrainAreaNSA|NSA]] || [[BrainRegionNSA_FD_TH_SG|NSA.FD.TH.SG]] || Suprageniculate Nucleus of Thalamus || excitatory-glu || (unknown reference)
+
| [[BrainAreaNSA|NSA]] || [[BrainRegionNSA_FD_TH_SG|NSA.FD.TH.SG]] || Suprageniculate Nucleus of Thalamus || excitatory-glu || uncertain ||(unknown reference)
 
|}
 
|}
  
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{| class=wikitable width=80%
 
{| class=wikitable width=80%
| '''Target Area''' || '''Target Region''' || '''Target Name''' || '''Type''' || '''Reference'''
+
| '''Target Area''' || '''Target Region''' || '''Target Name''' || '''Type''' || '''Role''' || '''Reference'''
 
|-
 
|-
| [[BrainAreaFEC|FEC]] || [[BrainRegionFEC_HT_TG_IPD|FEC.HT.TG.IPD]] || Interpeduncular Nucleus || modulatory-ach || (unknown reference)
+
| [[BrainAreaFEC|FEC]] || [[BrainRegionFEC_HT_TG_IPD|FEC.HT.TG.IPD]] || Interpeduncular Nucleus || modulatory-ach || uncertain || (unknown reference)
 
|-
 
|-
| [[BrainAreaFMM|FMM]] || [[BrainRegionFMM_FD_MB_LMB|FMM.FD.MB.LMB]] || Lateral Mammillary Nucleus || modulatory-ach || [http://ahuman.org/svn/ahengine/research/articles/2009-Hippocampus-Thesis.pdf Hippocampal Formation (DTN -> LMam)]
+
| [[BrainAreaFMM|FMM]] || [[BrainRegionFMM_FD_MB_LMB|FMM.FD.MB.LMB]] || Lateral Mammillary Nucleus || modulatory-ach || uncertain || [http://ahuman.org/svn/ahengine/research/articles/2009-Hippocampus-Thesis.pdf Hippocampal Formation (DTN -> LMam)]
 
|-
 
|-
| [[BrainAreaLAC|LAC]] || [[BrainRegionLAC_HL_SAL_ISL|LAC.HL.SAL.ISL]] || Inferior Salivatory Nucleus || modulatory-ach || (unknown reference)
+
| [[BrainAreaLAC|LAC]] || [[BrainRegionLAC_HL_SAL_ISL|LAC.HL.SAL.ISL]] || Inferior Salivatory Nucleus || modulatory-ach || uncertain || (unknown reference)
 
|-
 
|-
|  || [[BrainRegionLAC_HL_SAL_SSL|LAC.HL.SAL.SSL]] || Superior Salivatory Nucleus || modulatory-ach || (unknown reference)
+
|  || [[BrainRegionLAC_HL_SAL_SSL|LAC.HL.SAL.SSL]] || Superior Salivatory Nucleus || modulatory-ach || uncertain || (unknown reference)
 
|-
 
|-
| [[BrainAreaLRC|LRC]] || [[BrainRegionLRC_HL_NPH|LRC.HL.NPH]] || Prepositus Nucleus || modulatory-ach || [http://www.scholarpedia.org/article/Head_direction_cells Head Direction Cell Circuit (DTN -> NPRP)]
+
| [[BrainAreaLRC|LRC]] || [[BrainRegionLRC_HL_NPH|LRC.HL.NPH]] || Prepositus Nucleus || modulatory-ach || uncertain || [http://www.scholarpedia.org/article/Head_direction_cells Head Direction Cell Circuit (DTN -> NPRP)]
 
|-
 
|-
| [[BrainAreaNSA|NSA]] || [[BrainRegionNSA_FD_TH_SG|NSA.FD.TH.SG]] || Suprageniculate Nucleus of Thalamus || modulatory-ach || [http://www.scholarpedia.org/article/Head_direction_cells Head Direction Cell Circuit (DTN -> SUPGEN)]
+
| [[BrainAreaNSA|NSA]] || [[BrainRegionNSA_FD_TH_SG|NSA.FD.TH.SG]] || Suprageniculate Nucleus of Thalamus || modulatory-ach || uncertain || [http://www.scholarpedia.org/article/Head_direction_cells Head Direction Cell Circuit (DTN -> SUPGEN)]
 
|}
 
|}
  
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(generated)
 
(generated)
  
* [http://usvn.ahuman.org/svn/ahwiki/images/wiki/research/brain/HF.jpg Hippocampal Formation] - see [[article:2009-Hippocampus-Thesis.pdf|Reference]]
+
* [http://usvn.ahuman.org/svn/ahwiki/images/wiki/research/brain/HF.jpg Hippocampal Formation] - see [[article:2009-Hippocampus-Thesis.pdf|Reference]] (CT.HIPPOCAMPAL-FORMATION)
  
map: ATN=Anterior Nucleus of Thalamus,FD.TH.AN ([[BrainRegionNCP_FD_TH_AM|Anteromedial Nucleus]] (NCP.FD.TH.AM), [[BrainRegionFMM_FD_TH_AV|Anteroventral Nucleus]] (FMM.FD.TH.AV), [[BrainRegionFMM_FD_TH_AD|Anterodorsal Nucleus]] (FMM.FD.TH.AD)), CA1=Ventrolateral Cornu Ammonis of Hippocampus,FMM.FT.HC.CA1 ([[BrainRegionFMM_FT_HC_CA1P|Proximal CA1 of Hippocampus]] (FMM.FT.HC.CA1P), [[BrainRegionFMM_FT_HC_CA1M|Middle CA1 of Hippocampus]] (FMM.FT.HC.CA1M), [[BrainRegionFMM_FT_HC_CA1D|Distal CA1 of Hippocampus]] (FMM.FT.HC.CA1D)), CA3=Dorsomedial Cornu Ammonis of Hippocampus,FMM.FT.HC.CA3 ([[BrainRegionFMM_FT_HC_CA3P|Proximal CA3 of Hippocampus]] (FMM.FT.HC.CA3P), [[BrainRegionFMM_FT_HC_CA3M|Middle CA3 of Hippocampus]] (FMM.FT.HC.CA3M), [[BrainRegionFMM_FT_HC_CA3D|Distal CA3 of Hippocampus]] (FMM.FT.HC.CA3D)), DG=[[BrainRegionFMM_FT_HC_DG|Dentate Gyrus,FMM.FT.HC.DG]], DTN=[[BrainRegionLMC_HT_TG_LDT|Laterodorsal Tegmental Nucleus,LMC.HT.TG.LDT]], EC=Entorhinal Cortex,FMM.NC.PH.ET ([[BrainRegionFMM_NC_PH_LEC|Lateral Entorhinal Cortex]] (FMM.NC.PH.LEC), [[BrainRegionFMM_NC_PH_MEC|Medial Entorhinal Cortex]] (FMM.NC.PH.MEC)), LDN=[[BrainRegionFMM_FD_TH_LD|Lateral Dorsal Nucleus of Thalamus,FMM.FD.TH.LD]], LMam=[[BrainRegionFMM_FD_MB_LMB|Lateral Mammillary Nucleus,FMM.FD.MB.LMB]], PoS=[[BrainRegionFMM_NC_PH_POS|Postsubiculum,FMM.NC.PH.POS]], Rsp=[[BrainRegionNCP_NC_MPL_RSC|Retrosplenial Cortex,NCP.NC.MPL.RSC]], Sub=Subiculum,FMM.FT.HF.SUB ([[BrainRegionFMM_FT_HF_SUBP|Proximal Subiculum]] (FMM.FT.HF.SUBP), [[BrainRegionFMM_FT_HF_SUBM|Middle Subiculum]] (FMM.FT.HF.SUBM), [[BrainRegionFMM_FT_HF_SUBD|Distal Subiculum]] (FMM.FT.HF.SUBD))
+
ATN=Anterior Nucleus of Thalamus,FD.TH.AN (see [[BrainCenterFD_TH_CR|Cognitive Thalamus]])
<img src="http://ahuman.org/svn/ahwiki/images/ext/4d5651d77aacaaeda0f1c20e02778bf5.jpg" alt="unavailable" style="max-width: 100%;">
+
CA1=Ventrolateral Cornu Ammonis of Hippocampus,FMM.FT.HC.CA1 (see [[BrainCenterFMM_FT_HF|Hippocampal Formation]])
 +
CA3=Dorsomedial Cornu Ammonis of Hippocampus,FMM.FT.HC.CA3 (see [[BrainCenterFMM_FT_HF|Hippocampal Formation]])
 +
DG=[[BrainRegionFMM_FT_HC_DG|Dentate Gyrus,FMM.FT.HC.DG]]
 +
DTN=[[BrainRegionLMC_HT_TG_LDT|Laterodorsal Tegmental Nucleus,LMC.HT.TG.LDT]]
 +
EC=Entorhinal Cortex,FMM.NC.PH.ET (see [[BrainCenterNC_PHA_RH|Rhinal Cortex]])
 +
LDN=[[BrainRegionFMM_FD_TH_LD|Lateral Dorsal Nucleus of Thalamus,FMM.FD.TH.LD]]
 +
LMam=[[BrainRegionFMM_FD_MB_LMB|Lateral Mammillary Nucleus,FMM.FD.MB.LMB]]
 +
PoS=[[BrainRegionFMM_NC_PH_POS|Postsubiculum,FMM.NC.PH.POS]]
 +
Rsp=[[BrainRegionNCP_NC_MPL_RSC|Retrosplenial Cortex,NCP.NC.MPL.RSC]]
 +
Sub=Subiculum,FMM.FT.HF.SUB (see [[BrainCenterFMM_FT_HF|Hippocampal Formation]])
 +
<img src="http://ahuman.org/svn/ahwiki/images/ext/4d5651d77aacaaeda0f1c20e02778bf5.jpg" alt=alt="unavailable" style="max-width: 100%;" height=300 width=300>
  
* [http://www.scholarpedia.org/w/images/6/63/Taube_Figure_5a.png Head Direction Cell Circuit] - see [http://www.scholarpedia.org/article/Head_direction_cells Reference]
+
* [http://www.scholarpedia.org/w/images/6/63/Taube_Figure_5a.png Head Direction Cell Circuit] - see [http://www.scholarpedia.org/article/Head_direction_cells Reference] (CT.HEAD-DIRECTION)
  
map: AD=[[BrainRegionFMM_FD_TH_AD|Anterodorsal Nucleus,FMM.FD.TH.AD]], DTN=[[BrainRegionLMC_HT_TG_LDT|Laterodorsal Tegmental Nucleus,LMC.HT.TG.DTG]], EC=Entorhinal Cortex,FMM.NC.PH.ET ([[BrainRegionFMM_NC_PH_LEC|Lateral Entorhinal Cortex]] (FMM.NC.PH.LEC), [[BrainRegionFMM_NC_PH_MEC|Medial Entorhinal Cortex]] (FMM.NC.PH.MEC)), HC=Hippocampus,FMM.FT.HC ([[BrainRegionFMM_FT_HC_DG|Dentate Gyrus]] (FMM.FT.HC.DG), [[BrainRegionFMM_FT_HC_CA1P|Proximal CA1 of Hippocampus]] (FMM.FT.HC.CA1P), [[BrainRegionFMM_FT_HC_CA1M|Middle CA1 of Hippocampus]] (FMM.FT.HC.CA1M), [[BrainRegionFMM_FT_HC_CA1D|Distal CA1 of Hippocampus]] (FMM.FT.HC.CA1D), [[BrainRegionFMM_FT_HC_CA2|Dorsolateral Cornu Ammonis of Hippocampus]] (FMM.FT.HC.CA2), [[BrainRegionFMM_FT_HC_CA3P|Proximal CA3 of Hippocampus]] (FMM.FT.HC.CA3P), [[BrainRegionFMM_FT_HC_CA3M|Middle CA3 of Hippocampus]] (FMM.FT.HC.CA3M), [[BrainRegionFMM_FT_HC_CA3D|Distal CA3 of Hippocampus]] (FMM.FT.HC.CA3D)), IPD=[[BrainRegionFEC_HT_TG_IPD|Interpeduncular Nucleus,FEC.HT.TG.IPD]], LD=[[BrainRegionFMM_FD_TH_LD|Lateral Dorsal Nucleus of Thalamus,FMM.FD.TH.LD]], LHAB=[[BrainCenter|Habenula,FAM.FD.HB]], LMB=[[BrainRegionFMM_FD_MB_LMB|Lateral Mammillary Nucleus,FMM.FD.MB.LMB]], MVSN=[[BrainRegionLPC_HT_MVBN|Medial Vestibular Nucleus,LPC.HT.MVBN]], NPRP=[[BrainRegionLRC_HL_NPH|Prepositus Nucleus,LRC.HL.NPH]], PC=Parietal Lobe,NC.LOBE.PAR ([[BrainRegionNPE_NC_IPL_MST|Medial Superior Temporal Area]] (NPE.NC.IPL.MST), [[BrainRegionNPE_NC_IPL_SMW|Supramarginal Wernike Cortex]] (NPE.NC.IPL.SMW), [[BrainRegionNCP_NC_MPL_RSC|Retrosplenial Cortex]] (NCP.NC.MPL.RSC), [[BrainRegionNCP_NC_MPL_PSCG|Posterior Cingulate Cortex]] (NCP.NC.MPL.PSCG), [[BrainRegionNCP_NC_MPL_SGCG|Subgenual Cingulate Cortex]] (NCP.NC.MPL.SGCG), [[BrainRegionNCP_NC_PO_PCC|Precentral Cortex]] (NCP.NC.PO.PCC), [[BrainRegionNCP_NC_PG_S1|Primary Somatosensory Cortex]] (NCP.NC.PG.S1), [[BrainRegionNCP_NC_PG_S2|Secondary Somatosensory Cortex]] (NCP.NC.PG.S2), [[BrainRegionNCP_NC_PG_PV|Parietal Ventral Cortex]] (NCP.NC.PG.PV), [[BrainRegionNCP_NC_SPL_SA|Somatosensory Association Cortex]] (NCP.NC.SPL.SA), [[BrainRegionNPE_NC_SPL_PF|Rostral Precuneus]] (NPE.NC.SPL.PF), [[BrainRegionNPE_NC_SPL_PG|Caudal Precuneus]] (NPE.NC.SPL.PG), [[BrainRegionNPE_NC_IPS_MIP|Medial Intraparietal Sulcus]] (NPE.NC.IPS.MIP), [[BrainRegionNPE_NC_IPS_LIP|Lateral Intraparietal Sulcus]] (NPE.NC.IPS.LIP), [[BrainRegionNSA_NC_IPS_VIP|Ventral Intraparietal Sulcus]] (NSA.NC.IPS.VIP), [[BrainRegionNSA_NC_IPS_AIP|Anterior Intraparietal Sulcus]] (NSA.NC.IPS.AIP)), PRHC=[[BrainRegionFMM_NC_PH_POR|Postrhinal Cortex,FMM.NC.PH.POR]], PSUB=[[BrainRegionFMM_NC_PH_POS|Postsubiculum,FMM.NC.PH.POS]], RSP=[[BrainRegionNCP_NC_MPL_RSC|Retrosplenial Cortex,NCP.NC.MPL.RSC]], SUPGEN=[[BrainRegionNSA_FD_TH_SG|Suprageniculate Nucleus of Thalamus,NSA.FD.TH.SG]], VC=[[BrainCenter|Occipital Lobe,NC.LOBE.OCC]]
+
AD=[[BrainRegionFMM_FD_TH_AD|Anterodorsal Nucleus,FMM.FD.TH.AD]]
<img src="http://ahuman.org/svn/ahwiki/images/ext/1f4c1812ddb8ec93b53b4ed26dc3a381.png" alt="unavailable" style="max-width: 100%;">
+
DTN=[[BrainRegionLMC_HT_TG_LDT|Laterodorsal Tegmental Nucleus,LMC.HT.TG.DTG]]
 +
EC=Entorhinal Cortex,FMM.NC.PH.ET (see [[BrainCenterNC_PHA_RH|Rhinal Cortex]])
 +
HC=Hippocampus,FMM.FT.HC (see [[BrainCenterFMM_FT_HF|Hippocampal Formation]])
 +
IPD=[[BrainRegionFEC_HT_TG_IPD|Interpeduncular Nucleus,FEC.HT.TG.IPD]]
 +
LD=[[BrainRegionFMM_FD_TH_LD|Lateral Dorsal Nucleus of Thalamus,FMM.FD.TH.LD]]
 +
LHAB=[[BrainCenterFAM_FD_HB|Habenula,FAM.FD.HB]]
 +
LMB=[[BrainRegionFMM_FD_MB_LMB|Lateral Mammillary Nucleus,FMM.FD.MB.LMB]]
 +
MVSN=[[BrainRegionLPC_HT_MVBN|Medial Vestibular Nucleus,LPC.HT.MVBN]]
 +
NPRP=[[BrainRegionLRC_HL_NPH|Prepositus Nucleus,LRC.HL.NPH]]
 +
PC=Parietal Lobe,NC.LOBE.PAR
 +
PRHC=[[BrainRegionFMM_NC_PH_POR|Postrhinal Cortex,FMM.NC.PH.POR]]
 +
PSUB=[[BrainRegionFMM_NC_PH_POS|Postsubiculum,FMM.NC.PH.POS]]
 +
RSP=[[BrainRegionNCP_NC_MPL_RSC|Retrosplenial Cortex,NCP.NC.MPL.RSC]]
 +
SUPGEN=[[BrainRegionNSA_FD_TH_SG|Suprageniculate Nucleus of Thalamus,NSA.FD.TH.SG]]
 +
VC=[[BrainCenterNC_LOBE_OCC|Occipital Lobe,NC.LOBE.OCC]]
 +
<img src="http://ahuman.org/svn/ahwiki/images/ext/1f4c1812ddb8ec93b53b4ed26dc3a381.png" alt=alt="unavailable" style="max-width: 100%;">
  
* [http://www.frontiersin.org/files/Articles/70852/fnhum-07-00826-HTML/image_m/fnhum-07-00826-g002.jpg Regulation of the rapid eye movement (REM) sleep by habenular projection] - see [http://journal.frontiersin.org/article/10.3389/fnhum.2013.00826/full Reference]
+
* [http://www.frontiersin.org/files/Articles/70852/fnhum-07-00826-HTML/image_m/fnhum-07-00826-g002.jpg Regulation of the rapid eye movement (REM) sleep by habenular projection] - see [http://journal.frontiersin.org/article/10.3389/fnhum.2013.00826/full Reference] (CF.REM-HB)
  
map: DBB=[[BrainRegionFAM_FT_SEP_DBB|Diagonal Band of Broca,FAM.FT.SEP.DBB]], DTG=[[BrainRegionLMC_HT_TG_LDT|Laterodorsal Tegmental Nucleus,LMC.HT.TG.DTG]], EPN=[[BrainRegionFAM_FT_EPF|Endopiriform Nucleus,FAM.FT.EPF]], GPi=Globus Pallidus Internal,FEC.FT.GPI ([[BrainRegionFEC_FT_GPI_LT|Globus Pallidus Internal Lateral]] (FEC.FT.GPI.LT), [[BrainRegionFEC_FT_GPI_MED|Globus Pallidus Internal Medial]] (FEC.FT.GPI.MED), [[BrainRegionFEC_FT_GPI_DS|Globus Pallidus Internal Dorsal]] (FEC.FT.GPI.DS), [[BrainRegionFEC_FT_GPI_RM|Globus Pallidus Internal Rostromedial]] (FEC.FT.GPI.RM), [[BrainRegionFEC_FT_GPI_DL|Globus Pallidus Internal Dorsolateral]] (FEC.FT.GPI.DL)), LHT=[[BrainRegionLAC_FD_HT_LTN|Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN]], LHbL=[[BrainRegionFAM_FD_LHB_LT|Lateral Habenula Lateral Part,FAM.FD.LHB.LT]], LHbM=[[BrainRegionFAM_FD_LHB_MED|Lateral Habenula Medial Part,FAM.FD.LHB.MED]], NI=[[BrainRegionFAM_HT_TG_NI|Incertus Nucleus,FAM.HT.TG.NI]], RMTg=[[BrainRegionFEC_HT_TG_RMTG|Rostromedial Tegmental Nucleus,FEC.HT.TG.RMTG]], Raphe=Raphe Nuclei of Medulla,LMC.HL.RP ([[BrainRegionLMC_HL_RP_PL|Raphe Pallidus Nucleus]] (LMC.HL.RP.PL), [[BrainRegionLMC_HL_RP_OB|Raphe Obscurus Nucleus]] (LMC.HL.RP.OB), [[BrainRegionLMC_HL_RP_MG|Raphe Magnus Nucleus]] (LMC.HL.RP.MG)), SNc=Substantia Nigra Pars Compacta,FEC.FT.SNC ([[BrainRegionFEC_FT_SNC_LT|Substantia Nigra Pars Compacta Lateral]] (FEC.FT.SNC.LT), [[BrainRegionFEC_FT_SNC_MED|Substantia Nigra Pars Compacta Medial]] (FEC.FT.SNC.MED)), VTA=[[BrainRegionLMC_MM_VTA|Ventral Tegmental Area,LMC.MM.VTA]], VTG=[[BrainRegionLMC_MM_VTA|Ventral Tegmental Area,LMC.MM.VTG]]
+
DBB=[[BrainRegionFAM_FT_SEP_DBB|Diagonal Band of Broca,FAM.FT.SEP.DBB]]
<img src="http://ahuman.org/svn/ahwiki/images/ext/9876de47985d221848d9333bddb7bf59.jpg" alt="unavailable" style="max-width: 100%;">
+
DTG=[[BrainRegionLMC_HT_TG_LDT|Laterodorsal Tegmental Nucleus,LMC.HT.TG.DTG]]
 +
EPN=[[BrainRegionFAM_FT_EPF|Endopiriform Nucleus,FAM.FT.EPF]]
 +
GPi=Globus Pallidus Internal,FEC.FT.GPI (see [[BrainCenterFEC_FT_BG|Basal Ganglia]])
 +
LHT=[[BrainRegionLAC_FD_HT_LTN|Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN]]
 +
LHbL=[[BrainRegionFAM_FD_LHB_LT|Lateral Habenula Lateral Part,FAM.FD.LHB.LT]]
 +
LHbM=[[BrainRegionFAM_FD_LHB_MED|Lateral Habenula Medial Part,FAM.FD.LHB.MED]]
 +
NI=[[BrainRegionFAM_HT_TG_NI|Incertus Nucleus,FAM.HT.TG.NI]]
 +
RMTg=[[BrainRegionFEC_HT_TG_RMTG|Rostromedial Tegmental Nucleus,FEC.HT.TG.RMTG]]
 +
Raphe=Raphe Nuclei of Medulla,LMC.HL.RP (see [[BrainCenterHL_RF|Medullary Reticular Formation]])
 +
SNc=Substantia Nigra Pars Compacta,FEC.FT.SNC (see [[BrainCenterFEC_FT_BG|Basal Ganglia]])
 +
VTA=[[BrainRegionLMC_MM_VTA|Ventral Tegmental Area,LMC.MM.VTA]]
 +
VTG=[[BrainRegionLMC_MM_VTA|Ventral Tegmental Area,LMC.MM.VTG]]
 +
<img src="http://ahuman.org/svn/ahwiki/images/ext/9876de47985d221848d9333bddb7bf59.jpg" alt=alt="unavailable" style="max-width: 100%;">
  
* [http://www.nature.com/nrn/journal/v5/n1/images/nrn1299-f2.jpg Mammillary bodies: two memory systems in one] - see [http://www.nature.com/nrn/journal/v5/n1/fig_tab/nrn1299_F2.html Reference]
+
* [http://www.nature.com/nrn/journal/v5/n1/images/nrn1299-f2.jpg Mammillary bodies: two memory systems in one] - see [http://www.nature.com/nrn/journal/v5/n1/fig_tab/nrn1299_F2.html Reference] (CT.MB-MEMORY)
  
map: ADTH=[[BrainRegionFMM_FD_TH_AD|Anterodorsal Nucleus,FMM.FD.TH.AD]], AMTH=[[BrainRegionNCP_FD_TH_AM|Anteromedial Nucleus,NCP.FD.TH.AM]], AVTH=[[BrainRegionFMM_FD_TH_AV|Anteroventral Nucleus,FMM.FD.TH.AV]], DTN=[[BrainRegionLMC_HT_TG_LDT|Laterodorsal Tegmental Nucleus,LMC.HT.TG.LDT]], LMB=[[BrainRegionFMM_FD_MB_LMB|Lateral Mammillary Nucleus,FMM.FD.MB.LMB]], MMB=[[BrainRegionFMM_FD_MB_MMB|Medial Mammillary Nucleus,FMM.FD.MB.MMB]], MedialEC=Entorhinal Cortex,FMM.NC.PH.ET ([[BrainRegionFMM_NC_PH_LEC|Lateral Entorhinal Cortex]] (FMM.NC.PH.LEC), [[BrainRegionFMM_NC_PH_MEC|Medial Entorhinal Cortex]] (FMM.NC.PH.MEC)), PAS=[[BrainRegionFMM_NC_PH_PAS|Parasubiculum,FMM.NC.PH.PAS]], POS=[[BrainRegionFMM_NC_PH_POS|Postsubiculum,FMM.NC.PH.POS]], PRS=[[BrainRegionFMM_NC_PH_PRS|Presubiculum,FMM.NC.PH.PRS]], SEP=[[BrainCenter|Septal Nuclei,FAM.FT.SEP]], SUB=Subiculum,FMM.FT.HF.SUB ([[BrainRegionFMM_FT_HF_SUBP|Proximal Subiculum]] (FMM.FT.HF.SUBP), [[BrainRegionFMM_FT_HF_SUBM|Middle Subiculum]] (FMM.FT.HF.SUBM), [[BrainRegionFMM_FT_HF_SUBD|Distal Subiculum]] (FMM.FT.HF.SUBD)), SupraMM=[[BrainRegionLAC_FD_HT_SUM|Supramammillary Nucleus,LAC.FD.HT.SUM]], TuberoMM=Lateral Tuberal Nuclei,LAC.FD.HT.LTUB ([[BrainRegionLAC_FD_HT_SUM|Supramammillary Nucleus]] (LAC.FD.HT.SUM), [[BrainRegionLAC_FD_HT_TBM|Tuberomammillary Nucleus]] (LAC.FD.HT.TBM), [[BrainRegionLAC_FD_HT_PRM|Premammillary Nucleus]] (LAC.FD.HT.PRM)), VTN=[[BrainRegionLMC_MM_VTA|Ventral Tegmental Area,LMC.MM.VTA]]
+
ADTH=[[BrainRegionFMM_FD_TH_AD|Anterodorsal Nucleus,FMM.FD.TH.AD]]
<img src="http://ahuman.org/svn/ahwiki/images/ext/c973c3b2fef0f2bf256543a0a064fe81.jpg" alt="unavailable" style="max-width: 100%;">
+
AMTH=[[BrainRegionNCP_FD_TH_AM|Anteromedial Nucleus,NCP.FD.TH.AM]]
 +
AVTH=[[BrainRegionFMM_FD_TH_AV|Anteroventral Nucleus,FMM.FD.TH.AV]]
 +
DTN=[[BrainRegionLMC_HT_TG_LDT|Laterodorsal Tegmental Nucleus,LMC.HT.TG.LDT]]
 +
LMB=[[BrainRegionFMM_FD_MB_LMB|Lateral Mammillary Nucleus,FMM.FD.MB.LMB]]
 +
MMB=[[BrainRegionFMM_FD_MB_MMB|Medial Mammillary Nucleus,FMM.FD.MB.MMB]]
 +
MedialEC=Entorhinal Cortex,FMM.NC.PH.ET (see [[BrainCenterNC_PHA_RH|Rhinal Cortex]])
 +
PAS=[[BrainRegionFMM_NC_PH_PAS|Parasubiculum,FMM.NC.PH.PAS]]
 +
POS=[[BrainRegionFMM_NC_PH_POS|Postsubiculum,FMM.NC.PH.POS]]
 +
PRS=[[BrainRegionFMM_NC_PH_PRS|Presubiculum,FMM.NC.PH.PRS]]
 +
SEP=[[BrainCenterFAM_FT_SEP|Septal Nuclei,FAM.FT.SEP]]
 +
SUB=Subiculum,FMM.FT.HF.SUB (see [[BrainCenterFMM_FT_HF|Hippocampal Formation]])
 +
SupraMM=[[BrainRegionLAC_FD_HT_SUM|Supramammillary Nucleus,LAC.FD.HT.SUM]]
 +
TuberoMM=Lateral Tuberal Nuclei,LAC.FD.HT.LTUB (see [[BrainCenterFD_HT|Hypothalamus]])
 +
VTN=[[BrainRegionLMC_MM_VTA|Ventral Tegmental Area,LMC.MM.VTA]]
 +
<img src="http://ahuman.org/svn/ahwiki/images/ext/c973c3b2fef0f2bf256543a0a064fe81.jpg" alt=alt="unavailable" style="max-width: 100%;">
  
* [http://www.nature.com/neuro/journal/v5/n10/images/nn913-F1.jpg Simplified NREM sleep-promoting pathway] - see [http://www.nature.com/neuro/journal/v5/n10/fig_tab/nn913_F1.html Reference]
+
* [http://www.nature.com/neuro/journal/v5/n10/images/nn913-F1.jpg Simplified NREM sleep-promoting pathway] - see [http://www.nature.com/neuro/journal/v5/n10/fig_tab/nn913_F1.html Reference] (CL.TBM-PO)
  
map: LC=[[BrainRegionLMC_HT_LC|Locus Coeruleus,LMC.HT.LC]], LDTg=[[BrainRegionLMC_HT_TG_LDT|Laterodorsal Tegmental Nucleus,LMC.HT.TG.LDT]], TMN=[[BrainRegionLAC_FD_HT_TBM|Tuberomammillary Nucleus,LAC.FD.HT.TBM]], VLPO=[[BrainRegionLAC_FD_HT_VLPO|Ventrolateral Preoptic Nucleus,LAC.FD.HT.VLPO]]
+
LC=[[BrainRegionLMC_HT_LC|Locus Coeruleus,LMC.HT.LC]]
<img src="http://ahuman.org/svn/ahwiki/images/ext/7d1ab7f45d007c61b6a1b8abadde723d.jpg" alt="unavailable" style="max-width: 100%;">
+
LDTg=[[BrainRegionLMC_HT_TG_LDT|Laterodorsal Tegmental Nucleus,LMC.HT.TG.LDT]]
 +
TMN=[[BrainRegionLAC_FD_HT_TBM|Tuberomammillary Nucleus,LAC.FD.HT.TBM]]
 +
VLPO=[[BrainRegionLAC_FD_HT_VLPO|Ventrolateral Preoptic Nucleus,LAC.FD.HT.VLPO]]
 +
<img src="http://ahuman.org/svn/ahwiki/images/ext/7d1ab7f45d007c61b6a1b8abadde723d.jpg" alt=alt="unavailable" style="max-width: 100%;">
  
  

Latest revision as of 18:29, 28 April 2019

Laterodorsal Tegmental Nucleus

@@Home -> BiologicalLifeResearch -> BrainAreaLMC -> BrainRegionLMC_HT_TG_LDT


This page covers biological details of component Laterodorsal Tegmental Nucleus. Region is part of aHuman target integrated biological model.

  • Top-down path to region: Hindbrain Metencephalon -> Pontine Tegmental Nuclei (HT.TG) -> Laterodorsal Tegmental Nucleus (LMC.HT.TG.LDT) (see Mind Maps)
  • Type: nucleus
  • Quality: L0
  • Brain area: Lower Brain - Modulatory Contol Area (LMC)
  • Area circuit: Acetylcholine - PNS Actions and CNS plasticity, arousal and reward (ACH)
  • Role: processor.autonomic
  • Function: Modulating sustained attention or in mediating alerting responses
  • Notes to function:
    • sleep, waking, motor function, learning and reward

(generated)

Components

(generated)


Component items:

  • Lateral Tegmental Nucleus
  • Dorsal Tegmental Nucleus (LMC.HT.TG.DTG): accurate landmark navigation
    • Dorsal Tegmental Nucleus Pars Dorsalis
    • Dorsal Tegmental Nucleus Pars Ventralis

Connectivity

(generated)


LMC.HT.TG.LDT.dot.png

Inbound Region Connections:

Source Area Source Region Source Name Type Role Reference
FAM FAM.FD.LHB.MED Lateral Habenula Medial Part excitatory-glu uncertain Regulation of the rapid eye movement (REM) sleep by habenular projection (LHbM -> DTG)
FEC FEC.HT.TG.IPD Interpeduncular Nucleus modulatory-ach uncertain Head Direction Cell Circuit (IPD -> DTN)
FEC.HT.TG.RMTG Rostromedial Tegmental Nucleus inhibitory-gaba uncertain (unknown reference)
FMM FMM.FD.MB.LMB Lateral Mammillary Nucleus excitatory-glu uncertain Head Direction Cell Circuit (LMB -> DTN)
LAC LAC.FD.HT.VLPO Ventrolateral Preoptic Nucleus excitatory-glu uncertain Simplified NREM sleep-promoting pathway (VLPO -> LDTg)
LRC LRC.HL.NPH Prepositus Nucleus excitatory-glu uncertain (unknown reference)
NSA NSA.FD.TH.SG Suprageniculate Nucleus of Thalamus excitatory-glu uncertain (unknown reference)

Outbound Region Connections:

Target Area Target Region Target Name Type Role Reference
FEC FEC.HT.TG.IPD Interpeduncular Nucleus modulatory-ach uncertain (unknown reference)
FMM FMM.FD.MB.LMB Lateral Mammillary Nucleus modulatory-ach uncertain Hippocampal Formation (DTN -> LMam)
LAC LAC.HL.SAL.ISL Inferior Salivatory Nucleus modulatory-ach uncertain (unknown reference)
LAC.HL.SAL.SSL Superior Salivatory Nucleus modulatory-ach uncertain (unknown reference)
LRC LRC.HL.NPH Prepositus Nucleus modulatory-ach uncertain Head Direction Cell Circuit (DTN -> NPRP)
NSA NSA.FD.TH.SG Suprageniculate Nucleus of Thalamus modulatory-ach uncertain Head Direction Cell Circuit (DTN -> SUPGEN)

Thirdparty Circuits

(generated)

ATN=Anterior Nucleus of Thalamus,FD.TH.AN (see Cognitive Thalamus)
CA1=Ventrolateral Cornu Ammonis of Hippocampus,FMM.FT.HC.CA1 (see Hippocampal Formation)
CA3=Dorsomedial Cornu Ammonis of Hippocampus,FMM.FT.HC.CA3 (see Hippocampal Formation)
DG=Dentate Gyrus,FMM.FT.HC.DG
DTN=Laterodorsal Tegmental Nucleus,LMC.HT.TG.LDT
EC=Entorhinal Cortex,FMM.NC.PH.ET (see Rhinal Cortex)
LDN=Lateral Dorsal Nucleus of Thalamus,FMM.FD.TH.LD
LMam=Lateral Mammillary Nucleus,FMM.FD.MB.LMB
PoS=Postsubiculum,FMM.NC.PH.POS
Rsp=Retrosplenial Cortex,NCP.NC.MPL.RSC
Sub=Subiculum,FMM.FT.HF.SUB (see Hippocampal Formation)

AD=Anterodorsal Nucleus,FMM.FD.TH.AD
DTN=Laterodorsal Tegmental Nucleus,LMC.HT.TG.DTG
EC=Entorhinal Cortex,FMM.NC.PH.ET (see Rhinal Cortex)
HC=Hippocampus,FMM.FT.HC (see Hippocampal Formation)
IPD=Interpeduncular Nucleus,FEC.HT.TG.IPD
LD=Lateral Dorsal Nucleus of Thalamus,FMM.FD.TH.LD
LHAB=Habenula,FAM.FD.HB
LMB=Lateral Mammillary Nucleus,FMM.FD.MB.LMB
MVSN=Medial Vestibular Nucleus,LPC.HT.MVBN
NPRP=Prepositus Nucleus,LRC.HL.NPH
PC=Parietal Lobe,NC.LOBE.PAR
PRHC=Postrhinal Cortex,FMM.NC.PH.POR
PSUB=Postsubiculum,FMM.NC.PH.POS
RSP=Retrosplenial Cortex,NCP.NC.MPL.RSC
SUPGEN=Suprageniculate Nucleus of Thalamus,NSA.FD.TH.SG
VC=Occipital Lobe,NC.LOBE.OCC

DBB=Diagonal Band of Broca,FAM.FT.SEP.DBB
DTG=Laterodorsal Tegmental Nucleus,LMC.HT.TG.DTG
EPN=Endopiriform Nucleus,FAM.FT.EPF
GPi=Globus Pallidus Internal,FEC.FT.GPI (see Basal Ganglia)
LHT=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN
LHbL=Lateral Habenula Lateral Part,FAM.FD.LHB.LT
LHbM=Lateral Habenula Medial Part,FAM.FD.LHB.MED
NI=Incertus Nucleus,FAM.HT.TG.NI
RMTg=Rostromedial Tegmental Nucleus,FEC.HT.TG.RMTG
Raphe=Raphe Nuclei of Medulla,LMC.HL.RP (see Medullary Reticular Formation)
SNc=Substantia Nigra Pars Compacta,FEC.FT.SNC (see Basal Ganglia)
VTA=Ventral Tegmental Area,LMC.MM.VTA
VTG=Ventral Tegmental Area,LMC.MM.VTG

ADTH=Anterodorsal Nucleus,FMM.FD.TH.AD
AMTH=Anteromedial Nucleus,NCP.FD.TH.AM
AVTH=Anteroventral Nucleus,FMM.FD.TH.AV
DTN=Laterodorsal Tegmental Nucleus,LMC.HT.TG.LDT
LMB=Lateral Mammillary Nucleus,FMM.FD.MB.LMB
MMB=Medial Mammillary Nucleus,FMM.FD.MB.MMB
MedialEC=Entorhinal Cortex,FMM.NC.PH.ET (see Rhinal Cortex)
PAS=Parasubiculum,FMM.NC.PH.PAS
POS=Postsubiculum,FMM.NC.PH.POS
PRS=Presubiculum,FMM.NC.PH.PRS
SEP=Septal Nuclei,FAM.FT.SEP
SUB=Subiculum,FMM.FT.HF.SUB (see Hippocampal Formation)
SupraMM=Supramammillary Nucleus,LAC.FD.HT.SUM
TuberoMM=Lateral Tuberal Nuclei,LAC.FD.HT.LTUB (see Hypothalamus)
VTN=Ventral Tegmental Area,LMC.MM.VTA

LC=Locus Coeruleus,LMC.HT.LC
LDTg=Laterodorsal Tegmental Nucleus,LMC.HT.TG.LDT
TMN=Tuberomammillary Nucleus,LAC.FD.HT.TBM
VLPO=Ventrolateral Preoptic Nucleus,LAC.FD.HT.VLPO


References

(generated)