BrainRegionFMM FD MB LMB

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Lateral Mammillary Nucleus

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This page covers biological details of component Lateral Mammillary Nucleus. Region is part of aHuman target integrated biological model.

  • Top-down path to region: Forebrain Diencephalon -> Hypothalamus (FD.HT) -> Mammillary Body (FD.MB) -> Lateral Mammillary Nucleus (FMM.FD.MB.LMB) (see Mind Maps)
  • Type: nucleus
  • Brain area: Forebrain - Memory Management Area
  • Role: processor.memory.space
  • Function: Generate theta rythm and relay to HC
  • Notes to function: Memory, recognition, spatial awareness, and interpreting the context of events

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Components

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  • no child items defined

Connectivity

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FMM.FD.MB.LMB.dot.png

Inbound Region Connections:

Source Area Source Region Source Name Type Reference
FAM FAM.FT.SEP.MED Medial Septal Nucleus modulatory-ach Cingulate Gyrus (SEP -> HT, abstract)
FMM FMM.NC.PH.PAS Parasubiculum excitatory-glu Mammillary bodies: two memory systems in one (PAS -> LMB)
FMM.NC.PH.POS Postsubiculum excitatory-glu Head Direction Cell Circuit (PSUB -> LMB)
FMM.NC.PH.PRS Presubiculum excitatory-glu Mammillary bodies: two memory systems in one (PRS -> LMB)
LAC LAC.FD.HT.SUM Supramammillary Nucleus excitatory-glu Mammillary bodies: two memory systems in one (SupraMM -> LMB)
LMC LMC.HT.TG.LDT Laterodorsal Tegmental Nucleus modulatory-ach Hippocampal Formation (DTN -> LMam)

Outbound Region Connections:

Target Area Target Region Target Name Type Reference
FMM FMM.FD.TH.AD Anterodorsal Nucleus excitatory-glu Head Direction Cell Circuit (LMB -> AD)
LLC LLC.HT.PRF.RTMG Pontine Reticulotegmental Nucleus excitatory-glu Mammillary Body (LMB -> RTG)
LMC LMC.HT.TG.LDT Laterodorsal Tegmental Nucleus excitatory-glu Head Direction Cell Circuit (LMB -> DTN)

Thirdparty Circuits

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map: AD=Anterodorsal Nucleus,FMM.FD.TH.AD, DTN=Laterodorsal Tegmental Nucleus,LMC.HT.TG.DTG, EC=Entorhinal Cortex,FMM.NC.PH.ET (Lateral Entorhinal Cortex (FMM.NC.PH.LEC), Medial Entorhinal Cortex (FMM.NC.PH.MEC)), HC=Hippocampus,FMM.FT.HC (Dentate Gyrus (FMM.FT.HC.DG), Proximal CA1 of Hippocampus (FMM.FT.HC.CA1P), Middle CA1 of Hippocampus (FMM.FT.HC.CA1M), Distal CA1 of Hippocampus (FMM.FT.HC.CA1D), Dorsolateral Cornu Ammonis of Hippocampus (FMM.FT.HC.CA2), Proximal CA3 of Hippocampus (FMM.FT.HC.CA3P), Middle CA3 of Hippocampus (FMM.FT.HC.CA3M), Distal CA3 of Hippocampus (FMM.FT.HC.CA3D)), IPD=Interpeduncular Nucleus,FEC.HT.TG.IPD, LD=Lateral Dorsal Nucleus of Thalamus,FMM.FD.TH.LD, LHAB=Habenula,FAM.FD.HB, LMB=Lateral Mammillary Nucleus,FMM.FD.MB.LMB, MVSN=Medial Vestibular Nucleus,LPC.HT.MVBN, NPRP=Prepositus Nucleus,LRC.HL.NPH, PC=Parietal Lobe,NC.LOBE.PAR (Medial Superior Temporal Area (NPE.NC.IPL.MST), Supramarginal Wernike Cortex (NPE.NC.IPL.SMW), Retrosplenial Cortex (NCP.NC.MPL.RSC), Posterior Cingulate Cortex (NCP.NC.MPL.PSCG), Subgenual Cingulate Cortex (NCP.NC.MPL.SGCG), Precentral Cortex (NCP.NC.PO.PCC), Primary Somatosensory Cortex (NCP.NC.PG.S1), Secondary Somatosensory Cortex (NCP.NC.PG.S2), Parietal Ventral Cortex (NCP.NC.PG.PV), Somatosensory Association Cortex (NCP.NC.SPL.SA), Rostral Precuneus (NPE.NC.SPL.PF), Caudal Precuneus (NPE.NC.SPL.PG), Medial Intraparietal Sulcus (NPE.NC.IPS.MIP), Lateral Intraparietal Sulcus (NPE.NC.IPS.LIP), Ventral Intraparietal Sulcus (NSA.NC.IPS.VIP), Anterior Intraparietal Sulcus (NSA.NC.IPS.AIP)), PRHC=Postrhinal Cortex,FMM.NC.PH.POR, PSUB=Postsubiculum,FMM.NC.PH.POS, RSP=Retrosplenial Cortex,NCP.NC.MPL.RSC, SUPGEN=Suprageniculate Nucleus of Thalamus,NSA.FD.TH.SG, VC=Occipital Lobe,NC.LOBE.OCC unavailable

map: AN=Anterior Nucleus of Thalamus,FD.TH.AN (Anteromedial Nucleus (NCP.FD.TH.AM), Anteroventral Nucleus (FMM.FD.TH.AV), Anterodorsal Nucleus (FMM.FD.TH.AD)), CA1=Ventrolateral Cornu Ammonis of Hippocampus,FMM.FT.HC.CA1 (Proximal CA1 of Hippocampus (FMM.FT.HC.CA1P), Middle CA1 of Hippocampus (FMM.FT.HC.CA1M), Distal CA1 of Hippocampus (FMM.FT.HC.CA1D)), CA3=Dorsomedial Cornu Ammonis of Hippocampus,FMM.FT.HC.CA3 (Proximal CA3 of Hippocampus (FMM.FT.HC.CA3P), Middle CA3 of Hippocampus (FMM.FT.HC.CA3M), Distal CA3 of Hippocampus (FMM.FT.HC.CA3D)), DG=Dentate Gyrus,FMM.FT.HC.DG, EC=Entorhinal Cortex,FMM.NC.PH.ET (Lateral Entorhinal Cortex (FMM.NC.PH.LEC), Medial Entorhinal Cortex (FMM.NC.PH.MEC)), MBIN=Medial Mammillary Nucleus,FMM.FD.MB.MMB, MBOUT=Lateral Mammillary Nucleus,FMM.FD.MB.LMB, NACC=Accumbens Nucleus,FEC.FT.ACC (Nucleus Accumbens Core (FEC.FT.ACC.CORE), Nucleus Accumbens Shell (FEC.FT.ACC.SH)), PERI=Perirhinal Cortex,FMM.NC.PH.PER, PRESUB=Presubiculum,FMM.NC.PH.PRS, SEP=Septal Nuclei,FAM.FT.SEP, SUB=Subiculum,FMM.FT.HF.SUB (Proximal Subiculum (FMM.FT.HF.SUBP), Middle Subiculum (FMM.FT.HF.SUBM), Distal Subiculum (FMM.FT.HF.SUBD)) unavailable

map: ADTH=Anterodorsal Nucleus,FMM.FD.TH.AD, AMTH=Anteromedial Nucleus,NCP.FD.TH.AM, AVTH=Anteroventral Nucleus,FMM.FD.TH.AV, DTN=Laterodorsal Tegmental Nucleus,LMC.HT.TG.LDT, LMB=Lateral Mammillary Nucleus,FMM.FD.MB.LMB, MMB=Medial Mammillary Nucleus,FMM.FD.MB.MMB, MedialEC=Entorhinal Cortex,FMM.NC.PH.ET (Lateral Entorhinal Cortex (FMM.NC.PH.LEC), Medial Entorhinal Cortex (FMM.NC.PH.MEC)), PAS=Parasubiculum,FMM.NC.PH.PAS, POS=Postsubiculum,FMM.NC.PH.POS, PRS=Presubiculum,FMM.NC.PH.PRS, SEP=Septal Nuclei,FAM.FT.SEP, SUB=Subiculum,FMM.FT.HF.SUB (Proximal Subiculum (FMM.FT.HF.SUBP), Middle Subiculum (FMM.FT.HF.SUBM), Distal Subiculum (FMM.FT.HF.SUBD)), SupraMM=Supramammillary Nucleus,LAC.FD.HT.SUM, TuberoMM=Lateral Tuberal Nuclei,LAC.FD.HT.LTUB (Supramammillary Nucleus (LAC.FD.HT.SUM), Tuberomammillary Nucleus (LAC.FD.HT.TBM), Premammillary Nucleus (LAC.FD.HT.PRM)), VTN=Ventral Tegmental Area,LMC.MM.VTA unavailable

map: LMB=Lateral Mammillary Nucleus,FMM.FD.MB.LMB, MMB=Medial Mammillary Nucleus,FMM.FD.MB.MMB, RTG=Pontine Reticulotegmental Nucleus,LLC.HT.PRF.RTMG unavailable

map: ATN=Anterior Nucleus of Thalamus,FD.TH.AN (Anteromedial Nucleus (NCP.FD.TH.AM), Anteroventral Nucleus (FMM.FD.TH.AV), Anterodorsal Nucleus (FMM.FD.TH.AD)), CA1=Ventrolateral Cornu Ammonis of Hippocampus,FMM.FT.HC.CA1 (Proximal CA1 of Hippocampus (FMM.FT.HC.CA1P), Middle CA1 of Hippocampus (FMM.FT.HC.CA1M), Distal CA1 of Hippocampus (FMM.FT.HC.CA1D)), CA3=Dorsomedial Cornu Ammonis of Hippocampus,FMM.FT.HC.CA3 (Proximal CA3 of Hippocampus (FMM.FT.HC.CA3P), Middle CA3 of Hippocampus (FMM.FT.HC.CA3M), Distal CA3 of Hippocampus (FMM.FT.HC.CA3D)), DG=Dentate Gyrus,FMM.FT.HC.DG, DTN=Laterodorsal Tegmental Nucleus,LMC.HT.TG.LDT, EC=Entorhinal Cortex,FMM.NC.PH.ET (Lateral Entorhinal Cortex (FMM.NC.PH.LEC), Medial Entorhinal Cortex (FMM.NC.PH.MEC)), LDN=Lateral Dorsal Nucleus of Thalamus,FMM.FD.TH.LD, LMam=Lateral Mammillary Nucleus,FMM.FD.MB.LMB, PoS=Postsubiculum,FMM.NC.PH.POS, Rsp=Retrosplenial Cortex,NCP.NC.MPL.RSC, Sub=Subiculum,FMM.FT.HF.SUB (Proximal Subiculum (FMM.FT.HF.SUBP), Middle Subiculum (FMM.FT.HF.SUBM), Distal Subiculum (FMM.FT.HF.SUBD)) unavailable


References

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