BrainRegionNMA FD TH MDL

Lateral Mediodorsal Nucleus of Thalamus

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This page covers biological details of component Lateral Mediodorsal Nucleus of Thalamus. Region is part of aHuman target integrated biological model.

• Top-down path to region: Forebrain Diencephalon -> Thalamus (FD.TH) -> Cognitive Thalamus (FD.TH.CR) -> Mediodorsal Nucleus of Thalamus (FD.TH.MD) -> Lateral Mediodorsal Nucleus of Thalamus (NMA.FD.TH.MDL) (see Mind Maps)
• Type: nucleus
• Brain area: Neocortical Brain - Motor Aggregation Area
• Role: thalamic.cortex.reinforce
• Function: relay tegmentum to dorsal cingulate cortex
• Notes to function: Relay Superior Colliculus, TH-LD, LDTG, IPD to ACCdl

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Components

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• no child items defined

Connectivity

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Inbound Region Connections:

Source Area	Source Region	Source Name	Type	Reference
FEC	FEC.FT.SNR.MED	Substantia Nigra Pars Reticulata Medial	inhibitory-gaba	Saccadic Vision (BG -> Thalamus, abstract)
	FEC.FT.VP.DL	Ventral Pallidum Dorsolateral	inhibitory-gaba	Saccadic Vision (BG -> Thalamus, abstract)

Outbound Region Connections:

Target Area	Target Region	Target Name	Type	Reference
NDM	NDM.NC.AL.DACG	Dorsal Anterior Cingulate Area	excitatory-glu	Saccadic Vision (Thalamus -> FrontalCortex, abstract)
NPE	NPE.NC.PMC.AFEF	Anterior Frontal Eye Field	excitatory-glu	Oculomotor decision-making (Thalamus -> FEF, abstract)

Thirdparty Circuits

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• Saccadic Vision - see Reference (CP.SACCADIC-VISION)

BG=Basal Ganglia,FEC.FT.BG
CN=Caudate Nucleus,FEC.FT.CN (see Basal Ganglia)
CR=Cerebellum,LLC.HT.CR (see Cerebellar Complex)
FrontalCortex=Anterior Lobe,NC.LOBE.ANT
GPe=Globus Pallidus External,FEC.FT.GPE (see Basal Ganglia)
LGN=Lateral Geniculate Nucleus,NSA.FD.LGN
LIP=Lateral Intraparietal Sulcus,NPE.NC.IPS.LIP
RF=Pontine Reticular Formation,HT.RF
Retina=Retinal Nucleus,LPC.FD.RT
SCi=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon)
SCs=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon)
SNpr=Substantia Nigra Pars Reticulata Dorsolateral,FEC.FT.SNR.DL
STN=Subthalamic Nucleus,FEC.FD.STN (see Subthalamus Area)
Thalamus=Thalamus,FD.TH
VisualCortex=Occipital Lobe,NC.LOBE.OCC

• Oculomotor decision-making - see Reference (CP.OCULOMOTOR-DECISION-MAKING)

AMYG=Amygdala,FAM.FT.AM
CGa=Anterior Cingulate Cortex,NC.AL.ACG (see Anterior Cingulate Area)
CGp=Posterior Cingulate Cortex,NCP.NC.MPL.PSCG
Caudate=Caudate Nucleus,FEC.FT.CN (see Basal Ganglia)
FEF=Frontal Eye Field,NMA.NC.PMC.FEF (see Premotor Cortex)
LIP=Lateral Intraparietal Sulcus,NPE.NC.IPS.LIP
NAC=Accumbens Nucleus,FEC.FT.ACC (see Basal Ganglia)
OFC=Orbitofrontal Cortex,NC.AL.OPFC (see Orbitomedial Prefrontal Cortex)
PFC=Mid-Dorsolateral Prefrontal Cortex,NDM.NC.AL.DLPFC (see Lateral Prefrontal Cortex)
SC=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon)
SEF=Supplementary Eye Field,NPE.NC.SMC.SEF
SNc=Substantia Nigra Pars Compacta Lateral,FEC.FT.SNC.LT
SNr=Substantia Nigra Pars Reticulata Dorsolateral,FEC.FT.SNR.DL
Thalamus=Thalamus,FD.TH
VTA=Ventral Tegmental Area,LMC.MM.VTA

References

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• http://www.nature.com/nrn/journal/v5/n3/box/nrn1345_BX1.html
• http://www.springerimages.com/Images/LifeSciences/1-10.1007_s00359-004-0565-9-0