BrainRegionNCP NC PG S2

Secondary Somatosensory Cortex

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This page covers biological details of component Secondary Somatosensory Cortex. Region is part of aHuman target integrated biological model.

• Top-down path to region: Cerebral Cortex -> Parietal Lobe (NC.LOBE.PAR) -> Postcentral Gyrus (NC.PG) -> Lateral Parietal Cortex (NC.PG.LPC) -> Secondary Somatosensory Cortex (NCP.NC.PG.S2) (see Mind Maps)
• Type: cortex
• Quality: L0
• Brain area: Neocortical Brain - Conscious Personality Area (NCP)
• Area circuit: Neocortical Somatic Aggregation (SOM)
• Brodmann ID: 40
• Role: cortex.generic
• Function: Sensorimotor integration, integration of information from two body halves
• Notes to function:
  • BA 1/3b
  • projects to PV/7b/INS/AM/HC

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Components

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• no child items defined

Connectivity

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Inbound Region Connections:

Source Area	Source Region	Source Name	Type	Role	Reference
NCP	NCP.FD.TH.VPI	Ventral Posteroinferior Nucleus	excitatory-glu	uncertain	Afferent pain pathways (Thalamus -> S2, abstract)
	NCP.FD.TH.VPL	Ventral Posterolateral Nucleus	excitatory-glu	uncertain	Afferent pain pathways (Thalamus -> S2, abstract)
	NCP.FD.TH.VPM	Ventral Posteromedial Nucleus	excitatory-glu	uncertain	Afferent pain pathways (Thalamus -> S2, abstract)
	NCP.NC.PG.S1	Primary Somatosensory Cortex	feedforward-glu	uncertain	Afferent pain pathways (S1 -> S2)

Outbound Region Connections:

Target Area	Target Region	Target Name	Type	Role	Reference
NCP	NCP.NC.PG.PV	Parietal Ventral Cortex	feedforward-glu	uncertain	(unknown reference)
NMA	NMA.NC.MC	Motor Cortex	feedforward-glu	uncertain	Global visual system (ParietalCortex -> FrontalCortex, abstract)
NPE	NPE.NC.IPL.SMW	Supramarginal Wernike Cortex	feedforward-glu	uncertain	(unknown reference)
	NPE.NC.SPL.PF	Rostral Precuneus	feedforward-glu	uncertain	(unknown reference)

Thirdparty Circuits

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• Global visual system - see Reference (CP.GLOBAL-VISUAL-SYSTEM)

ATH=Anterior Nucleus of Thalamus,FD.TH.AN (see Cognitive Thalamus)
BGA=Basal Ganglia,FEC.FT.BG
FrontalCortex=Anterior Lobe,NC.LOBE.ANT
LGN=Lateral Geniculate Nucleus,NSA.FD.LGN
OPN=Oculomotor Nucleus,LPC.MM.OCN
ParietalCortex=Parietal Lobe,NC.LOBE.PAR
Pulvinar=Pulvinar,FD.PV (see Sensory Thalamus)
RF=Pontine Reticular Formation,HT.RF
Retina=Retinal Nucleus,LPC.FD.RT
SCi=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon)
SCs=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon)
SNc=Substantia Nigra Pars Compacta Lateral,FEC.FT.SNC.LT
SNr=Substantia Nigra Pars Reticulata Dorsolateral,FEC.FT.SNR.DL
SpinalCord=Lamina IX,SC.VH.L9 (see Anterior/Ventral Horn)
Striatum=Striatum,FEC.FT.ST (see Basal Ganglia)
VisualCortex=Occipital Lobe,NC.LOBE.OCC

• Afferent pain pathways - see Reference (CF.PAIN-PATH)

ACC=Anterior Cingulate Cortex,NC.AL.ACG (see Anterior Cingulate Area)
AMY=Amygdala,FAM.FT.AM
BG=Basal Ganglia,FEC.FT.BG
Cerebellum=Cerebellar Complex,LLC.HT.CRC
Insula=Insular Cortex,NC.INS
PAG=Periaqueductal Gray Matter,LMC.MM.PAG
PB=Parabrachial Nucleus,LPC.HT.PRF.PB
PFC=Prefrontal Cortex,NC.AL.PFC
S1=Primary Somatosensory Cortex,NCP.NC.PG.S1
S2=Secondary Somatosensory Cortex,NCP.NC.PG.S2
SC=Posterior/Dorsal Horn,BMA.SC.PH
Thalamus=Sensory Thalamus,FD.TH.SR

References

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• http://www.sciencedirect.com/science/article/pii/S0959438808001566
• http://www.nature.com/nrn/journal/v14/n7/fig_tab/nrn3516_F2.html