Forebrain Execution Control Area

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Local Circuits

(generated)

Limbic Loop

unavailable

|| *Component ID* || *Component Name* || *Type* || *Service* || *Function* || *Comments* || || FEC.FD.STN.DL || Subthalamic Nucleus Dorsolateral || nucleus || FEU || Motivational loop || || || FEC.FT.CN.TL || Caudate Nucleus Tail || nucleus || FEU || Successful classification learning, correct categorization || ITC, STC || || FEC.FT.GPE.RM || Globus Pallidus External Rostromedial || nucleus || FEU || Motivational loop || || || FEC.FT.GPI.RM || Globus Pallidus Internal Rostromedial || nucleus || FEU || Motivational loop || || || FEC.FT.PU.VT || Ventral Putamen || nucleus || FEU || Evaluation of flavors, taste, motivation loop || || || FEC.FT.SNR.MED || Substantia Nigra Pars Reticulata Medial || nucleus || FEU || Motivational loop || ||

Internal Region Connections:*

|| *Source Region* || *Target Region* || *Type* || *Reference* || || FEC.FD.STN.DL || BrainRegionFEC_FT_GPE_RM FEC.FT.GPE.RM || nucleus-nucleus || (unknown reference) || || || FEC.FT.GPI.RM || nucleus-nucleus || [Basal Ganglia Activity (STN -> GPi, abstract)] || || || FEC.FT.PU.VT || nucleus-nucleus || (unknown reference) || || || FEC.FT.SNR.MED || nucleus-nucleus || (unknown reference) || || FEC.FT.CN.TL || BrainRegionFEC_FT_GPI_RM FEC.FT.GPI.RM || nucleus-nucleus-gaba || [Habenula Connections (CPu -> GPi, abstract)] || || || FEC.FT.SNR.MED || nucleus-nucleus-gaba || [Saccades and smooth movements (CN -> SN, abstract)] || || FEC.FT.GPE.RM || BrainRegionFEC_FT_GPI_RM FEC.FT.GPI.RM || nucleus-nucleus-gaba || (unknown reference) || || || FEC.FT.SNR.MED || nucleus-nucleus-gaba || [Prefrontal Cortex (PFC) in motor behavior (GP -> SN, abstract)] || || FEC.FT.PU.VT || BrainRegionFEC_FT_SNR_MED FEC.FT.SNR.MED || nucleus-nucleus-gaba || (unknown reference) ||

External Inbound Region Connections:*

|| *Source Area* || *Local Region* || *Source Region* || *Source Name* || *Type* || *Reference* || || Cortical || || || || || || || NDM || BrainRegionFEC_FD_STN_DL FEC.FD.STN.DL || BrainRegionNDM_NC_AL_ROFCR NDM.NC.AL.ROFCR || Most Rostral Orbitofrontal Cortex || neocortex-nucleus || (unknown reference) || || || FEC.FT.CN.TL || BrainRegionNDM_NC_AL_ROFCR NDM.NC.AL.ROFCR || Most Rostral Orbitofrontal Cortex || neocortex-nucleus || [Global visual system (FrontalCortex -> BGA, abstract)] || || || FEC.FT.PU.VT || BrainRegionNDM_NC_AL_VACG NDM.NC.AL.VACG || Ventral Anterior Cingulate Area || neocortex-nucleus || [Global visual system (FrontalCortex -> BGA, abstract)] || || || FEC.FT.SNR.MED || BrainRegionNDM_NC_AL_FPC NDM.NC.AL.FPC || Lateral Frontopolar Cortex || neocortex-nucleus || [Global visual system (FrontalCortex -> BGA, abstract)] || || Subcortical || || || || || || || FAM || BrainRegionFEC_FT_CN_TL FEC.FT.CN.TL || BrainRegionFAM_FT_AM_AB FAM.FT.AM.AB || Accessory Basal Amygdaloid Nucleus || nucleus-nucleus || (unknown reference) ||

External Outbound Region Connections:*

|| *Target Area* || *Local Region* || *Target Region* || *Target Name* || *Type* || *Reference* || || Cortical || || || || || || || NDM || BrainRegionFEC_FT_GPI_RM FEC.FT.GPI.RM || BrainRegionNDM_FD_TH_MDM NDM.FD.TH.MDM || Medial Mediodorsal Nucleus of Thalamus || nucleus-nucleus-gaba || [Saccadic Vision (BG -> Thalamus, abstract)] || || NMA || BrainRegionFEC_FT_SNR_MED FEC.FT.SNR.MED || BrainRegionNMA_FD_TH_MDL NMA.FD.TH.MDL || Lateral Mediodorsal Nucleus of Thalamus || nucleus-nucleus-gaba || [Saccadic Vision (BG -> Thalamus, abstract)] || || Subcortical || || || || || || || FAM || BrainRegionFEC_FT_SNR_MED FEC.FT.SNR.MED || BrainRegionFAM_HP_PPN_IPD FAM.HP.PPN.IPD || Interpeduncular Nucleus || nucleus-nucleus-gaba || (unknown reference) || || FEC || BrainRegionFEC_FT_GPI_RM FEC.FT.GPI.RM || BrainRegionFEC_FT_SNC_MED FEC.FT.SNC.MED || Substantia Nigra Pars Compacta Medial || nucleus-nucleus-gaba || [Prefrontal Cortex (PFC) in motor behavior (GP -> SN, abstract)] || || || FEC.FT.SNR.MED || BrainRegionFEC_FT_SNC_MED FEC.FT.SNC.MED || Substantia Nigra Pars Compacta Medial || nucleus-nucleus-gaba || (unknown reference) ||

Executive/Cognitive Loop

unavailable

|| *Component ID* || *Component Name* || *Type* || *Service* || *Function* || *Comments* || || FEC.FD.STN.CD || Subthalamic Nucleus Caudal || nucleus || FEU || Executive loop || || || FEC.FT.CN.HD || Caudate Nucleus Head || nucleus || FEU || Feedback processing, result of incorrect categorization || LPFC, BA 9 || || FEC.FT.GPE.DS || Globus Pallidus External Dorsal || nucleus || FEU || Executive loop || || || FEC.FT.GPI.DS || Globus Pallidus Internal Dorsal || nucleus || FEU || Executive loop || output nucleus for caudate nucleus || || FEC.FT.SNC.LT || Substantia Nigra Pars Compacta Lateral || nucleus || FEU || executive loop || || || FEC.FT.SNR.RM || Substantia Nigra Pars Reticulata Rostromedial || nucleus || FEU || Executive loop || ||

Internal Region Connections:*

|| *Source Region* || *Target Region* || *Type* || *Reference* || || FEC.FD.STN.CD || BrainRegionFEC_FT_GPE_DS FEC.FT.GPE.DS || nucleus-nucleus || (unknown reference) || || || FEC.FT.GPI.DS || nucleus-nucleus || [Basal Ganglia Activity (STN -> GPi, abstract)] || || || FEC.FT.SNR.RM || nucleus-nucleus || (unknown reference) || || FEC.FT.CN.HD || BrainRegionFEC_FT_GPI_DS FEC.FT.GPI.DS || nucleus-nucleus-gaba || [Habenula Connections (CPu -> GPi, abstract)] || || || FEC.FT.SNC.LT || nucleus-nucleus-gaba || [Saccades and smooth movements (CN -> SN, abstract)] || || || FEC.FT.SNR.RM || nucleus-nucleus-gaba || [Saccades and smooth movements (CN -> SN, abstract)] || || FEC.FT.GPE.DS || BrainRegionFEC_FT_GPI_DS FEC.FT.GPI.DS || nucleus-nucleus-gaba || (unknown reference) || || || FEC.FT.SNR.RM || nucleus-nucleus-gaba || [Prefrontal Cortex (PFC) in motor behavior (GP -> SN, abstract)] || || FEC.FT.GPI.DS || BrainRegionFEC_FT_SNC_LT FEC.FT.SNC.LT || nucleus-nucleus-gaba || [Prefrontal Cortex (PFC) in motor behavior (GP -> SN, abstract)] || || FEC.FT.SNR.RM || BrainRegionFEC_FT_SNC_LT FEC.FT.SNC.LT || nucleus-nucleus-gaba || (unknown reference) ||

External Inbound Region Connections:*

|| *Source Area* || *Local Region* || *Source Region* || *Source Name* || *Type* || *Reference* || || Cortical || || || || || || || NDM || BrainRegionFEC_FD_STN_CD FEC.FD.STN.CD || BrainRegionNDM_NC_AL_DACG NDM.NC.AL.DACG || Dorsal Anterior Cingulate Area || neocortex-nucleus || (unknown reference) || || || FEC.FT.CN.HD || BrainRegionNDM_NC_AL_DACG NDM.NC.AL.DACG || Dorsal Anterior Cingulate Area || neocortex-nucleus || [Global visual system (FrontalCortex -> BGA, abstract)] || || || || NDM.NC.AL.DLPFCL || Lateral Mid-Dorsolateral Prefrontal Cortex || neocortex-nucleus || [Global visual system (FrontalCortex -> BGA, abstract)] || || Subcortical || || || || || || || FAM || BrainRegionFEC_FT_SNC_LT FEC.FT.SNC.LT || BrainRegionFAM_FD_LHB_MED FAM.FD.LHB.MED || Lateral Habenula Medial Part || nucleus-nucleus || [Habenula Connections (LHb -> SNc, abstract)] || || || || FAM.HP.PPN.IPD || Interpeduncular Nucleus || nucleus-nucleus-ACh || (unknown reference) || || LAC || BrainRegionFEC_FD_STN_CD FEC.FD.STN.CD || BrainRegionLAC_FD_HT_VM LAC.FD.HT.VM || Ventromedial Hypothalamic Nucleus || nucleus-nucleus || (unknown reference) || || LRC || BrainRegionFEC_FT_SNC_LT FEC.FT.SNC.LT || BrainRegionLRC_MM_SC_DEEP LRC.MM.SC.DEEP || Deep Superior Colliculus || nucleus-nucleus || [Global visual system (SCi -> SNc, abstract)] ||

External Outbound Region Connections:*

|| *Target Area* || *Local Region* || *Target Region* || *Target Name* || *Type* || *Reference* || || Cortical || || || || || || || NMA || BrainRegionFEC_FT_GPI_DS FEC.FT.GPI.DS || BrainRegionNMA_FD_TH_VA NMA.FD.TH.VA || Ventral Anterior Nucleus || nucleus-nucleus-gaba || [Thalamocortical relationships (sVA -> VA, abstract)] || || Subcortical || || || || || || || FAM || BrainRegionFEC_FT_GPI_DS FEC.FT.GPI.DS || BrainRegionFAM_FD_LHB_LT FAM.FD.LHB.LT || Lateral Habenula Lateral Part || nucleus-nucleus-gaba || [Habenula Connections (GPi -> LHb, abstract)] || || FEC || BrainRegionFEC_FT_SNC_LT FEC.FT.SNC.LT || BrainRegionFEC_FT_PU_LT FEC.FT.PU.LT || Dorsal Putamen Lateral || nucleus-nucleus-DA || [Physiology and pathophysiology of lower urinary tract (SNC -> PU)] || || || || FEC.FT.PU.MED || Dorsal Putamen Medial || nucleus-nucleus-DA || (unknown reference) || || LLC || BrainRegionFEC_FT_SNC_LT FEC.FT.SNC.LT || BrainRegionLLC_MM_RD LLC.MM.RD || Red Nucleus || nucleus-nucleus-DA || (unknown reference) || || LMC || BrainRegionFEC_FD_STN_CD FEC.FD.STN.CD || BrainRegionLMC_FT_NBM LMC.FT.NBM || Basal Nucleus of Meynert || nucleus-nucleus || (unknown reference) ||

Motivational Loop

unavailable

|| *Component ID* || *Component Name* || *Type* || *Service* || *Function* || *Comments* || || FEC.FD.TH.RH || Rhomboidal Nucleus of Thalamus || nucleus || FMU || Communication of information across memory delays to guide memory responses || like RE, return projection from PFC to HC, spatial
working memory || || FEC.FT.ACC.CORE || Nucleus Accumbens Core || nucleus || FEU || cognitive processing of motor function related to reward and reinforcement;
encodes new motor programs which facilitate acquisition of given reward in future || || || FEC.FT.ACC.SH || Nucleus Accumbens Shell || nucleus || FEU || cognitive processing of motivational salience (wanting) as well as reward and
reinforcement effects || || || FEC.FT.IPAC.LT || Lateral Interstitial Anterior Commissural Nucleus || nucleus || FAU || Striatal territory || innervates the pallidal complex, substantia nigra
and retrorubral field || || FEC.FT.SNC.MED || Substantia Nigra Pars Compacta Medial || nucleus || FEU || motivational loop || || || FEC.FT.VP.DL || Ventral Pallidum Dorsolateral || nucleus || FEU || motivational loop, NAcc-core || || || FEC.FT.VP.VM || Ventral Pallidum Ventromedial || nucleus || FEU || motivational loop, NAcc-shell || ||

Internal Region Connections:*

|| *Source Region* || *Target Region* || *Type* || *Reference* || || FEC.FD.TH.RH || BrainRegionFEC_FT_ACC_CORE FEC.FT.ACC.CORE || nucleus-nucleus || (unknown reference) || || FEC.FT.ACC.CORE || BrainRegionFEC_FT_SNC_MED FEC.FT.SNC.MED || nucleus-nucleus-gaba || (unknown reference) || || || FEC.FT.VP.DL || nucleus-nucleus-gaba || [Craving (NACC -> VPAL, abstract)] || || FEC.FT.ACC.SH || BrainRegionFEC_FT_IPAC_LT FEC.FT.IPAC.LT || nucleus-nucleus-gaba || (unknown reference) || || || FEC.FT.VP.VM || nucleus-nucleus-gaba || [Craving (NACC -> VPAL, abstract)] || || FEC.FT.IPAC.LT || BrainRegionFEC_FT_VP_VM FEC.FT.VP.VM || nucleus-nucleus-gaba || (unknown reference) || || FEC.FT.SNC.MED || BrainRegionFEC_FT_ACC_SH FEC.FT.ACC.SH || nucleus-nucleus-DA || (unknown reference) ||

External Inbound Region Connections:*

|| *Source Area* || *Local Region* || *Source Region* || *Source Name* || *Type* || *Reference* || || Cortical || || || || || || || NCP || BrainRegionFEC_FT_ACC_SH FEC.FT.ACC.SH || BrainRegionNCP_NC_MPL_PSCG NCP.NC.MPL.PSCG || Posterior Cingulate Cortex || neocortex-nucleus || (unknown reference) || || NDM || BrainRegionFEC_FD_TH_RH FEC.FD.TH.RH || BrainRegionNDM_NC_AL_ROFCR NDM.NC.AL.ROFCR || Most Rostral Orbitofrontal Cortex || neocortex-nucleus || (unknown reference) || || || FEC.FT.ACC.CORE || BrainRegionNDM_NC_AL_FPC NDM.NC.AL.FPC || Lateral Frontopolar Cortex || neocortex-nucleus || [Affective basal ganglia circuit (OMPFC -> NACC, abstract)] || || || FEC.FT.ACC.SH || BrainRegionNDM_NC_AL_VACG NDM.NC.AL.VACG || Ventral Anterior Cingulate Area || neocortex-nucleus || [Global visual system (FrontalCortex -> BGA, abstract)] || || Subcortical || || || || || || || FAM || BrainRegionFEC_FT_ACC_CORE FEC.FT.ACC.CORE || BrainRegionFAM_FD_TH_PT FAM.FD.TH.PT || Paratenial Nucleus of Thalamus || nucleus-nucleus || (unknown reference) || || || || FAM.FT.AM.BP || Parvicellular Basal Amygdaloid Nucleus || nucleus-nucleus || [Amygdala and its network (BLN -> NACC, abstract)] || || || FEC.FT.SNC.MED || BrainRegionFAM_FT_BNST FAM.FT.BNST || Bed Nucleus of Stria Terminalis || nucleus-nucleus || (unknown reference) || || FEC || BrainRegionFEC_FT_SNC_MED FEC.FT.SNC.MED || BrainRegionFEC_FT_GPI_RM FEC.FT.GPI.RM || Globus Pallidus Internal Rostromedial || nucleus-nucleus-gaba || [Prefrontal Cortex (PFC) in motor behavior (GP -> SN, abstract)] || || || || FEC.FT.SNR.MED || Substantia Nigra Pars Reticulata Medial || nucleus-nucleus-gaba || (unknown reference) || || FMM || BrainRegionFEC_FT_ACC_CORE FEC.FT.ACC.CORE || BrainRegionFMM_FT_HF_SUBD FMM.FT.HF.SUBD || Distal Subiculum || allocortex-nucleus || [Nucleus Accumbens (SUB -> NACC, abstract)] || || || || FMM.FT.HF.SUBP || Proximal Subiculum || allocortex-nucleus || [Nucleus Accumbens (SUB -> NACC, abstract)] || || || || FMM.NC.PH.LEC || Lateral Entorhinal Cortex || neocortex-nucleus || [Nucleus Accumbens (EC -> NACC, abstract)] || || || || FMM.NC.PH.PAS || Parasubiculum || neocortex-nucleus || [Nucleus Accumbens (PAS -> NACC, abstract)] || || || || FMM.NC.PH.PER || Perirhinal Cortex || neocortex-nucleus || [Nucleus Accumbens (PRR -> NACC, abstract)] || || LMC || BrainRegionFEC_FT_ACC_SH FEC.FT.ACC.SH || BrainRegionLMC_MM_VTA LMC.MM.VTA || Ventral Tegmental Area || nucleus-nucleus-DA || [Craving (VTA -> NACC, abstract)] || || || FEC.FT.SNC.MED || BrainRegionLMC_HP_LC LMC.HP.LC || Locus Coeruleus || nucleus-nucleus-NE || (unknown reference) || || LPC || BrainRegionFEC_FT_ACC_CORE FEC.FT.ACC.CORE || BrainRegionLPC_FD_TH_PV LPC.FD.TH.PV || Paraventricular Nucleus of Thalamus || nucleus-nucleus || (unknown reference) ||

External Outbound Region Connections:*

|| *Target Area* || *Local Region* || *Target Region* || *Target Name* || *Type* || *Reference* || || Subcortical || || || || || || || FAM || BrainRegionFEC_FT_SNC_MED FEC.FT.SNC.MED || BrainRegionFAM_FT_AM_CEM FAM.FT.AM.CEM || Medial Central Amygdaloid Nucleus || nucleus-nucleus-DA || (unknown reference) || || || FEC.FT.VP.VM || BrainRegionFAM_FD_LHB_MED FAM.FD.LHB.MED || Lateral Habenula Medial Part || nucleus-nucleus-gaba || (unknown reference) || || FEC || BrainRegionFEC_FT_IPAC_LT FEC.FT.IPAC.LT || BrainRegionFEC_FT_SNR_DL FEC.FT.SNR.DL || Substantia Nigra Pars Reticulata Dorsolateral || nucleus-nucleus-gaba || (unknown reference) || || FMM || BrainRegionFEC_FD_TH_RH FEC.FD.TH.RH || BrainRegionFMM_FT_HF_SUBP FMM.FT.HF.SUBP || Proximal Subiculum || nucleus-allocortex || [Contributions of Diencephalon to Recognition Memory (MID -> SubPrePara, abstract)] || || LAC || BrainRegionFEC_FT_ACC_SH FEC.FT.ACC.SH || BrainRegionLAC_FD_HT_LTN LAC.FD.HT.LTN || Lateral Hypothalamic Nucleus || nucleus-nucleus-gaba || (unknown reference) || || || FEC.FT.SNC.MED || BrainRegionLAC_FD_HT_SUM LAC.FD.HT.SUM || Supramammillary Nucleus || nucleus-nucleus-DA || (unknown reference) || || LMC || BrainRegionFEC_FT_ACC_CORE FEC.FT.ACC.CORE || BrainRegionLMC_MM_VTA LMC.MM.VTA || Ventral Tegmental Area || nucleus-nucleus-gaba || [Reward circuit of human brain (NACC -> VTA, abstract)] || || || FEC.FT.ACC.SH || BrainRegionLMC_FT_NBM LMC.FT.NBM || Basal Nucleus of Meynert || nucleus-nucleus-gaba || [Affective basal ganglia circuit (NACC -> nBM, abstract)] || || LRC || BrainRegionFEC_FT_SNC_MED FEC.FT.SNC.MED || BrainRegionLRC_HP_PRF_PVR LRC.HP.PRF.PVR || Parvocellular Reticular Nucleus || nucleus-nucleus-DA || (unknown reference) ||

Motor Extensor Loop

unavailable

|| *Component ID* || *Component Name* || *Type* || *Service* || *Function* || *Comments* || || FEC.FD.STN.MED || Subthalamic Nucleus Medial || nucleus || FEU || Motor Extensor loop || || || FEC.FD.TH.PF || Parafascicular Nucleus of Thalamus || nucleus || FEU || Stimulation of acetylcholine release in dorsal striata || Part of ascending activating system || || FEC.FT.GPE.MED || Globus Pallidus External Medial || nucleus || FEU || Flexor loop || Body extensor movements, trunk and girdles || || FEC.FT.GPI.MED || Globus Pallidus Internal Medial || nucleus || FEU || Motor extensor loop || indirect path || || FEC.FT.PU.MED || Dorsal Putamen Medial || nucleus || FEU || Extensor motor initiation || dorsomedial, SMC and PMC - overlap, BA 6,46 || || FEC.FT.SNR.DL || Substantia Nigra Pars Reticulata Dorsolateral || nucleus || FEU || Extensor motor loop, head || ||

Internal Region Connections:*

|| *Source Region* || *Target Region* || *Type* || *Reference* || || FEC.FD.STN.MED || BrainRegionFEC_FT_GPE_MED FEC.FT.GPE.MED || nucleus-nucleus || (unknown reference) || || || FEC.FT.GPI.MED || nucleus-nucleus || [Basal Ganglia Activity (STN -> GPi, abstract)] || || || FEC.FT.SNR.DL || nucleus-nucleus || [Saccadic Vision (STN -> SNpr, abstract)] || || FEC.FD.TH.PF || BrainRegionFEC_FT_PU_MED FEC.FT.PU.MED || nucleus-nucleus || (unknown reference) || || FEC.FT.GPE.MED || BrainRegionFEC_FT_GPI_MED FEC.FT.GPI.MED || nucleus-nucleus-gaba || (unknown reference) || || || FEC.FT.SNR.DL || nucleus-nucleus-gaba || [Prefrontal Cortex (PFC) in motor behavior (GP -> SN, abstract)] || || FEC.FT.GPI.MED || BrainRegionFEC_FD_TH_PF FEC.FD.TH.PF || nucleus-nucleus-gaba || [Saccadic Vision (BG -> Thalamus, abstract)] || || FEC.FT.PU.MED || BrainRegionFEC_FT_GPE_MED FEC.FT.GPE.MED || nucleus-nucleus-gaba || (unknown reference) || || || FEC.FT.GPI.MED || nucleus-nucleus-gaba || (unknown reference) || || || FEC.FT.SNR.DL || nucleus-nucleus-gaba || (unknown reference) ||

External Inbound Region Connections:*

|| *Source Area* || *Local Region* || *Source Region* || *Source Name* || *Type* || *Reference* || || Cortical || || || || || || || NMA || BrainRegionFEC_FD_STN_MED FEC.FD.STN.MED || BrainRegionNMA_NC_SMC_F6 NMA.NC.SMC.F6 || Pre-Supplementary Motor Area || neocortex-nucleus || (unknown reference) || || || FEC.FT.PU.MED || BrainRegionNMA_NC_PMC_F2 NMA.NC.PMC.F2 || Dorsal Caudal Premotor Cortex || neocortex-nucleus || (unknown reference) || || || || NMA.NC.PMC.F5 || Ventral Rostral Premotor Cortex || neocortex-nucleus || (unknown reference) || || || || NMA.NC.SMC.F3 || Supplementary Motor Area || neocortex-nucleus || (unknown reference) || || Subcortical || || || || || || || FAM || BrainRegionFEC_FD_TH_PF FEC.FD.TH.PF || BrainRegionFAM_FT_SEP_MED FAM.FT.SEP.MED || Medial Septal Nucleus || nucleus-nucleus-ACh || (unknown reference) || || FEC || BrainRegionFEC_FT_PU_MED FEC.FT.PU.MED || BrainRegionFEC_FT_SNC_LT FEC.FT.SNC.LT || Substantia Nigra Pars Compacta Lateral || nucleus-nucleus-DA || (unknown reference) || || || FEC.FT.SNR.DL || BrainRegionFEC_FT_IPAC_LT FEC.FT.IPAC.LT || Lateral Interstitial Anterior Commissural Nucleus || nucleus-nucleus-gaba || (unknown reference) ||

External Outbound Region Connections:*

|| *Target Area* || *Local Region* || *Target Region* || *Target Name* || *Type* || *Reference* || || Cortical || || || || || || || NMA || BrainRegionFEC_FT_GPI_MED FEC.FT.GPI.MED || BrainRegionNMA_FD_TH_VA NMA.FD.TH.VA || Ventral Anterior Nucleus || nucleus-nucleus-gaba || [Thalamocortical relationships (sVA -> VA, abstract)] || || || FEC.FT.SNR.DL || BrainRegionNMA_FD_TH_VA NMA.FD.TH.VA || Ventral Anterior Nucleus || nucleus-nucleus-gaba || [Thalamocortical relationships (sVA -> VA, abstract)] ||

Motor Flexor Loop

unavailable

|| *Component ID* || *Component Name* || *Type* || *Service* || *Function* || *Comments* || || FEC.FD.STN.LT || Subthalamic Nucleus Lateral || nucleus || FEU || Motor Flexor loop || || || FEC.FD.TH.CM || Centromedian Nucleus of Thalamus || nucleus || FEU || Control of level of cortical activity || Lesions lead to persistent vegetative state || || FEC.FD.TH.RIL || Rostral Intralaminar Nuclear Group of Thalamus || nucleus || FEU || cognitive functions || from SC LVII,LVIII/CR nuclei to striatum || || FEC.FT.GPE.LT || Globus Pallidus External Lateral || nucleus || FEU || Flexor loop || || || FEC.FT.GPI.LT || Globus Pallidus Internal Lateral || nucleus || FEU || Motor flexor loop || output nuclei of basal ganglia to neocortex, leg,
arm, face; lateral - leg, medial - arm, ventral -
face || || FEC.FT.PU.LT || Dorsal Putamen Lateral || nucleus || FEU || Flexor motor initiation || ventrolateral, D1 receptor, MC and S1 - overlap,
TH/CM from GPi; DL-leg, RL-face, VM-arms ||

Internal Region Connections:*

|| *Source Region* || *Target Region* || *Type* || *Reference* || || FEC.FD.STN.LT || BrainRegionFEC_FT_GPE_LT FEC.FT.GPE.LT || nucleus-nucleus || (unknown reference) || || || FEC.FT.GPI.LT || nucleus-nucleus || [Basal Ganglia Activity (STN -> GPi, abstract)] || || FEC.FD.TH.CM || BrainRegionFEC_FT_PU_LT FEC.FT.PU.LT || nucleus-nucleus || (unknown reference) || || FEC.FD.TH.RIL || BrainRegionFEC_FT_PU_LT FEC.FT.PU.LT || nucleus-nucleus || (unknown reference) || || FEC.FT.GPE.LT || BrainRegionFEC_FT_GPI_LT FEC.FT.GPI.LT || nucleus-nucleus-gaba || (unknown reference) || || FEC.FT.GPI.LT || BrainRegionFEC_FD_TH_CM FEC.FD.TH.CM || nucleus-nucleus-gaba || [Thalamocortical relationships (sCM -> CM, abstract)] || || FEC.FT.PU.LT || BrainRegionFEC_FT_GPI_LT FEC.FT.GPI.LT || nucleus-nucleus-gaba || (unknown reference) ||

External Inbound Region Connections:*

|| *Source Area* || *Local Region* || *Source Region* || *Source Name* || *Type* || *Reference* || || Cortical || || || || || || || NMA || BrainRegionFEC_FD_STN_LT FEC.FD.STN.LT || BrainRegionNMA_NC_MC NMA.NC.MC || Motor Cortex || neocortex-nucleus || (unknown reference) || || || FEC.FT.PU.LT || BrainRegionNMA_NC_MC NMA.NC.MC || Motor Cortex || neocortex-nucleus || (unknown reference) || || NSA || BrainRegionFEC_FT_PU_LT FEC.FT.PU.LT || BrainRegionNSA_NC_PG_S1 NSA.NC.PG.S1 || Primary Somatosensory Cortex || neocortex-nucleus || (unknown reference) || || Subcortical || || || || || || || FAM || BrainRegionFEC_FD_STN_LT FEC.FD.STN.LT || BrainRegionFAM_HP_PPN_IPD FAM.HP.PPN.IPD || Interpeduncular Nucleus || nucleus-nucleus-ACh || (unknown reference) || || FEC || BrainRegionFEC_FT_PU_LT FEC.FT.PU.LT || BrainRegionFEC_FT_SNC_LT FEC.FT.SNC.LT || Substantia Nigra Pars Compacta Lateral || nucleus-nucleus-DA || [Physiology and pathophysiology of lower urinary tract (SNC -> PU)] || || LLC || BrainRegionFEC_FD_TH_CM FEC.FD.TH.CM || BrainRegionLLC_HP_CR_EN LLC.HP.CR.EN || Emboliform Nucleus || nucleus-nucleus || (unknown reference) || || || FEC.FD.TH.RIL || BrainRegionLLC_HP_CR_DN LLC.HP.CR.DN || Dentate Nucleus || nucleus-nucleus || (unknown reference) || || || || LLC.SC.IZ.CCV || Central Cervical Nucleus || nucleus-nucleus || (unknown reference) ||

External Outbound Region Connections:*

|| *Target Area* || *Local Region* || *Target Region* || *Target Name* || *Type* || *Reference* || || Cortical || || || || || || || NMA || BrainRegionFEC_FT_GPI_LT FEC.FT.GPI.LT || BrainRegionNMA_FD_TH_VL NMA.FD.TH.VL || Ventral Lateral Nucleus || nucleus-nucleus-gaba || [Thalamocortical relationships (s2VL -> VL, abstract)] || || NPE || BrainRegionFEC_FD_TH_RIL FEC.FD.TH.RIL || BrainRegionNPE_NC_SPL_SA NPE.NC.SPL.SA || Somatosensory Association Cortex || nucleus-neocortex || (unknown reference) || || Subcortical || || || || || || || FAM || BrainRegionFEC_FD_STN_LT FEC.FD.STN.LT || BrainRegionFAM_HP_PPN_RMTG FAM.HP.PPN.RMTG || Rostromedial Tegmental Nucleus || nucleus-nucleus || (unknown reference) ||

Oculomotor and Auditory/Association Loop

unavailable

|| *Component ID* || *Component Name* || *Type* || *Service* || *Function* || *Comments* || || FEC.FD.STN.ICD || Subthalamic Nucleus Internal Caudal || nucleus || FEU || Oculomotor loop || || || FEC.FD.TH.LI || Limitans Nucleus of Thalamus || nucleus || LUS || Multisensory projection to striatum || From SC, trigeminal nucleus, superior and inferior
colliculus || || FEC.FT.CN.BD || Caudate Nucleus Body || nucleus || FEU || Oculomotor learning || FEF, SEF || || FEC.FT.GPE.DL || Globus Pallidus External Dorsolateral || nucleus || FEU || Oculomotor loop || || || FEC.FT.GPI.DL || Globus Pallidus Internal Dorsolateral || nucleus || FEU || Oculomotor loop || || || FEC.FT.SNR.VL || Substantia Nigra Pars Reticulata Ventrolateral || nucleus || FEU || Oculomotor loop || ||