Lateral Hypothalamic Nucleus

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This page covers biological details of component Lateral Hypothalamic Nucleus. Region is part of aHuman target integrated biological model.

Top-down path to region: Forebrain Diencephalon -> Hypothalamus (FD.HT) -> Lateral Hypothalamic Area (LAC.FD.HT.LT) -> Lateral Hypothalamic Nucleus (LAC.FD.HT.LTN) (see Mind Maps)
Type: nucleus
Brain area: Lower Brain - Autonomous Control Area
Role: relay
Function: feeding center
Notes to function: lesions - lack of appetite

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Components

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Connectivity

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LAC.FD.HT.LTN.dot.png

Inbound Region Connections:

Source Area	Source Region	Source Name	Type	Reference
FAM	FAM.FT.AM.BP	Parvicellular Basal Amygdaloid Nucleus	excitatory-glu	Amygdala and its network (BLN -> HTS)
	FAM.FT.AM.CEM	Medial Central Amygdaloid Nucleus	excitatory-glu	Amygdalar disruption of prefrontal cortex (AM -> HT.L, abstract)
	FAM.FT.SEP.SH	Septohippocampal Nucleus	excitatory-glu	Cingulate Gyrus (SEP -> HT, abstract)
FEC	FEC.FT.ACC.SH	Nucleus Accumbens Shell	inhibitory-gaba	(unknown reference)
LAC	LAC.FD.HT.AR	Arcuate Nucleus of Hypothalamus	excitatory-glu	Intrahypothalamic connections important for neural control of food intake and energy balance (ARC -> LHA)
	LAC.FD.HT.DM	Dorsomedial Hypothalamic Nucleus	excitatory-glu	Eating and sleeping to survive (DMH -> LHA)

Outbound Region Connections:

Target Area	Target Region	Target Name	Type	Reference
FAM	FAM.FD.LHB.LT	Lateral Habenula Lateral Part	excitatory-glu	Regulation of the rapid eye movement (REM) sleep by habenular projection (LHT -> LHbL)
	FAM.FD.LHB.MED	Lateral Habenula Medial Part	excitatory-glu	Both LHb and MHb control the dopaminergic and serotonergic systems (LHA -> LHbM)
FMM	FMM.FD.MB.LMB	Lateral Mammillary Nucleus	excitatory-glu	(unknown reference)
	FMM.FD.MB.MMB	Medial Mammillary Nucleus	excitatory-glu	(unknown reference)
LMC	LMC.HL.RP.MG	Raphe Magnus Nucleus	excitatory-glu	(unknown reference)