BrainRegionFEC FT GPI RM

Globus Pallidus Internal Rostromedial

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This page covers biological details of component Globus Pallidus Internal Rostromedial. Region is part of aHuman target integrated biological model.

• Top-down path to region: Forebrain Telencephalon -> Basal Ganglia (FEC.FT.BG) -> Globus Pallidus (FEC.FT.GP) -> Dorsal Pallidum (FEC.FT.DP) -> Globus Pallidus Internal (FEC.FT.GPI) -> Globus Pallidus Internal Rostromedial (FEC.FT.GPI.RM) (see Mind Maps)
• Type: nucleus
• Quality: L0
• Brain area: Forebrain - Execution Control Area
• Role: basal.ganglia.suppress
• Function: Motivational loop

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Components

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• no child items defined

Connectivity

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Inbound Region Connections:

Source Area	Source Region	Source Name	Type	Reference
FEC	FEC.FD.STN.DL	Subthalamic Nucleus Dorsolateral	excitatory-glu	Basal Ganglia Activity (STN -> GPi, abstract)
	FEC.FT.CN.TL	Caudate Nucleus Tail	inhibitory-gaba	Habenula Connections (CPu -> GPi, abstract)
	FEC.FT.GPE.RM	Globus Pallidus External Rostromedial	inhibitory-gaba	(unknown reference)

Outbound Region Connections:

Target Area	Target Region	Target Name	Type	Reference
FEC	FEC.FT.SNC.MED	Substantia Nigra Pars Compacta Medial	inhibitory-gaba	Prefrontal Cortex (PFC) in motor behavior (GP -> SN, abstract)
NDM	NDM.FD.TH.MDM	Medial Mediodorsal Nucleus of Thalamus	inhibitory-gaba	Saccadic Vision (BG -> Thalamus, abstract)

Thirdparty Circuits

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• Saccadic Vision - see Reference (CP.SACCADIC-VISION)

BG=Basal Ganglia,FEC.FT.BG
CN=Caudate Nucleus,FEC.FT.CN (see Basal Ganglia)
CR=Cerebellum,LLC.HT.CR (see Cerebellar Complex)
FrontalCortex=Anterior Lobe,NC.LOBE.ANT
GPe=Globus Pallidus External,FEC.FT.GPE (see Basal Ganglia)
LGN=Lateral Geniculate Nucleus,NSA.FD.LGN
LIP=Lateral Intraparietal Sulcus,NPE.NC.IPS.LIP
RF=Pontine Reticular Formation,HT.RF
Retina=Retinal Nucleus,LPC.FD.RT
SCi=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon)
SCs=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon)
SNpr=Substantia Nigra Pars Reticulata Dorsolateral,FEC.FT.SNR.DL
STN=Subthalamic Nucleus,FEC.FD.STN (see Subthalamus Area)
Thalamus=Thalamus,FD.TH
VisualCortex=Occipital Lobe,NC.LOBE.OCC

• Prefrontal Cortex (PFC) in motor behavior - see Reference (CM.PFC-MOTOR)

CN.PU=Striatum,FEC.FT.ST (see Basal Ganglia)
CR=Cerebellar Complex,LLC.HT.CRC
GP=Globus Pallidus,FEC.FT.GP (see Basal Ganglia)
LPFC=Mid-Dorsolateral Prefrontal Cortex,NDM.NC.AL.DLPFC (see Lateral Prefrontal Cortex)
MC=Motor Cortex,NMA.NC.MC
PMC=Premotor Cortex,NC.PMC
PN=Pontine Nuclear Complex,HT.PN (see Metencephalic Sensory Nuclei)
SN=Substantia Nigra,FEC.FT.SN (see Basal Ganglia)
TH=Ventral Thalamus,FD.TH.VTH (see Motor Thalamus)

References

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• http://www.nature.com/nrn/journal/v5/n3/box/nrn1345_BX1.html
• https://www.google.ru/search?hl=rutbo=ptbm=bksq=isbn:0080887988