BrainRegionFMM FD MB LMB
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Lateral Mammillary Nucleus
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This page covers biological details of component Lateral Mammillary Nucleus. Region is part of aHuman target integrated biological model.
- Top-down path to region: Forebrain Diencephalon -> Hypothalamus (FD.HT) -> Mammillary Body (FD.MB) -> Lateral Mammillary Nucleus (FMM.FD.MB.LMB) (see Mind Maps)
- Type: nucleus
- Brain area: Forebrain - Memory Management Area
- Role: processor.memory.space
- Function: Generate theta rythm and relay to HC
- Notes to function:
- Memory, recognition, spatial awareness, and interpreting the context of events
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Components
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- no child items defined
Connectivity
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Inbound Region Connections:
| Source Area | Source Region | Source Name | Type | Reference |
| FAM | FAM.FT.SEP.MED | Medial Septal Nucleus | modulatory-ach | Cingulate Gyrus (SEP -> HT, abstract) |
| FMM | FMM.NC.PH.PAS | Parasubiculum | excitatory-glu | Mammillary bodies: two memory systems in one (PAS -> LMB) |
| FMM.NC.PH.POS | Postsubiculum | excitatory-glu | Head Direction Cell Circuit (PSUB -> LMB) | |
| FMM.NC.PH.PRS | Presubiculum | excitatory-glu | Mammillary bodies: two memory systems in one (PRS -> LMB) | |
| LAC | LAC.FD.HT.SUM | Supramammillary Nucleus | excitatory-glu | Mammillary bodies: two memory systems in one (SupraMM -> LMB) |
| LMC | LMC.HT.TG.LDT | Laterodorsal Tegmental Nucleus | modulatory-ach | Hippocampal Formation (DTN -> LMam) |
Outbound Region Connections:
| Target Area | Target Region | Target Name | Type | Reference |
| FMM | FMM.FD.TH.AD | Anterodorsal Nucleus | excitatory-glu | Head Direction Cell Circuit (LMB -> AD) |
| LLC | LLC.HT.PRF.RTMG | Pontine Reticulotegmental Nucleus | excitatory-glu | Mammillary Body (LMB -> RTG) |
| LMC | LMC.HT.TG.LDT | Laterodorsal Tegmental Nucleus | excitatory-glu | Head Direction Cell Circuit (LMB -> DTN) |
Thirdparty Circuits
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- Head Direction Cell Circuit - see Reference (CT.HEAD-DIRECTION)
AD=Anterodorsal Nucleus,FMM.FD.TH.AD DTN=Laterodorsal Tegmental Nucleus,LMC.HT.TG.DTG EC=Entorhinal Cortex,FMM.NC.PH.ET (see Rhinal Cortex) HC=Hippocampus,FMM.FT.HC (see Hippocampal Formation) IPD=Interpeduncular Nucleus,FEC.HT.TG.IPD LD=Lateral Dorsal Nucleus of Thalamus,FMM.FD.TH.LD LHAB=Habenula,FAM.FD.HB LMB=Lateral Mammillary Nucleus,FMM.FD.MB.LMB MVSN=Medial Vestibular Nucleus,LPC.HT.MVBN NPRP=Prepositus Nucleus,LRC.HL.NPH PC=Parietal Lobe,NC.LOBE.PAR PRHC=Postrhinal Cortex,FMM.NC.PH.POR PSUB=Postsubiculum,FMM.NC.PH.POS RSP=Retrosplenial Cortex,NCP.NC.MPL.RSC SUPGEN=Suprageniculate Nucleus of Thalamus,NSA.FD.TH.SG VC=Occipital Lobe,NC.LOBE.OCC
- Attractor Network in Hippocampus - see Reference (CT.ATTRACTOR-NETWORK)
AN=Anterior Nucleus of Thalamus,FD.TH.AN (see Cognitive Thalamus) CA1=Ventrolateral Cornu Ammonis of Hippocampus,FMM.FT.HC.CA1 (see Hippocampal Formation) CA3=Dorsomedial Cornu Ammonis of Hippocampus,FMM.FT.HC.CA3 (see Hippocampal Formation) DG=Dentate Gyrus,FMM.FT.HC.DG EC=Entorhinal Cortex,FMM.NC.PH.ET (see Rhinal Cortex) MBIN=Medial Mammillary Nucleus,FMM.FD.MB.MMB MBOUT=Lateral Mammillary Nucleus,FMM.FD.MB.LMB NACC=Accumbens Nucleus,FEC.FT.ACC (see Basal Ganglia) PERI=Perirhinal Cortex,FMM.NC.PH.PER PRESUB=Presubiculum,FMM.NC.PH.PRS SEP=Septal Nuclei,FAM.FT.SEP SUB=Subiculum,FMM.FT.HF.SUB (see Hippocampal Formation)
- Mammillary bodies: two memory systems in one - see Reference (CT.MB-MEMORY)
ADTH=Anterodorsal Nucleus,FMM.FD.TH.AD AMTH=Anteromedial Nucleus,NCP.FD.TH.AM AVTH=Anteroventral Nucleus,FMM.FD.TH.AV DTN=Laterodorsal Tegmental Nucleus,LMC.HT.TG.LDT LMB=Lateral Mammillary Nucleus,FMM.FD.MB.LMB MMB=Medial Mammillary Nucleus,FMM.FD.MB.MMB MedialEC=Entorhinal Cortex,FMM.NC.PH.ET (see Rhinal Cortex) PAS=Parasubiculum,FMM.NC.PH.PAS POS=Postsubiculum,FMM.NC.PH.POS PRS=Presubiculum,FMM.NC.PH.PRS SEP=Septal Nuclei,FAM.FT.SEP SUB=Subiculum,FMM.FT.HF.SUB (see Hippocampal Formation) SupraMM=Supramammillary Nucleus,LAC.FD.HT.SUM TuberoMM=Lateral Tuberal Nuclei,LAC.FD.HT.LTUB (see Hypothalamus) VTN=Ventral Tegmental Area,LMC.MM.VTA
- Mammillary Body (unknown reference) (CT.LMB-MMB)
LMB=Lateral Mammillary Nucleus,FMM.FD.MB.LMB MMB=Medial Mammillary Nucleus,FMM.FD.MB.MMB RTG=Pontine Reticulotegmental Nucleus,LLC.HT.PRF.RTMG
- Hippocampal Formation - see Reference (CT.HIPPOCAMPAL-FORMATION)
ATN=Anterior Nucleus of Thalamus,FD.TH.AN (see Cognitive Thalamus) CA1=Ventrolateral Cornu Ammonis of Hippocampus,FMM.FT.HC.CA1 (see Hippocampal Formation) CA3=Dorsomedial Cornu Ammonis of Hippocampus,FMM.FT.HC.CA3 (see Hippocampal Formation) DG=Dentate Gyrus,FMM.FT.HC.DG DTN=Laterodorsal Tegmental Nucleus,LMC.HT.TG.LDT EC=Entorhinal Cortex,FMM.NC.PH.ET (see Rhinal Cortex) LDN=Lateral Dorsal Nucleus of Thalamus,FMM.FD.TH.LD LMam=Lateral Mammillary Nucleus,FMM.FD.MB.LMB PoS=Postsubiculum,FMM.NC.PH.POS Rsp=Retrosplenial Cortex,NCP.NC.MPL.RSC Sub=Subiculum,FMM.FT.HF.SUB (see Hippocampal Formation)
References
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