Nucleus Accumbens Core

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This page covers biological details of component Nucleus Accumbens Core. Region is part of aHuman target integrated biological model.

Top-down path to region: Forebrain Telencephalon -> Basal Ganglia (FEC.FT.BG) -> Striatum (FEC.FT.ST) -> Ventral Striatum (FEC.FT.VST) -> Accumbens Nucleus (FEC.FT.ACC) -> Nucleus Accumbens Core (FEC.FT.ACC.CORE) (see Mind Maps)
Type: nucleus
Brain area: Forebrain - Execution Control Area
Role: relay
Function: cognitive processing of motor function related to reward and reinforcement; encodes new motor programs which facilitate acquisition of given reward in future

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Components

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Connectivity

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FEC.FT.ACC.CORE.dot.png

Inbound Region Connections:

Source Area	Source Region	Source Name	Type	Reference
FAM	FAM.FD.TH.PT	Paratenial Nucleus of Thalamus	excitatory-glu	(unknown reference)
	FAM.FT.AM.BP	Parvicellular Basal Amygdaloid Nucleus	excitatory-glu	Amygdala and its network (BLN -> NACC, abstract)
FMM	FMM.FD.TH.RH	Rhomboidal Nucleus of Thalamus	excitatory-glu	(unknown reference)
	FMM.FT.HC.CA1D	Distal CA1 of Hippocampus	excitatory-glu	Nucleus Accumbens (CA1 -> NACC, abstract)
	FMM.FT.HF.SUBD	Distal Subiculum	excitatory-glu	Nucleus Accumbens (SUB -> NACC, abstract)
	FMM.FT.HF.SUBP	Proximal Subiculum	excitatory-glu	Nucleus Accumbens (SUB -> NACC, abstract)
	FMM.NC.PH.LEC	Lateral Entorhinal Cortex	excitatory-glu	Nucleus Accumbens (EC -> NACC, abstract)
	FMM.NC.PH.PAS	Parasubiculum	excitatory-glu	Nucleus Accumbens (PAS -> NACC, abstract)
	FMM.NC.PH.PER	Perirhinal Cortex	excitatory-glu	Nucleus Accumbens (PRR -> NACC, abstract)
LPC	LPC.FD.TH.PV	Paraventricular Nucleus of Thalamus	excitatory-glu	(unknown reference)
NDM	NDM.NC.AL.FPC	Lateral Frontopolar Cortex	excitatory-glu	Affective basal ganglia circuit (OMPFC -> NACC, abstract)

Outbound Region Connections:

Target Area	Target Region	Target Name	Type	Reference
FAM	FAM.FD.LHB.LT	Lateral Habenula Lateral Part	inhibitory-gaba	Connectivity map of the habenula (NAc -> L, abstract)
FEC	FEC.FT.SNC.MED	Substantia Nigra Pars Compacta Medial	inhibitory-gaba	(unknown reference)
	FEC.FT.SNR.MED	Substantia Nigra Pars Reticulata Medial	inhibitory-gaba	Craving (NACC -> SNr, abstract)
	FEC.FT.VP.DL	Ventral Pallidum Dorsolateral	inhibitory-gaba	Craving (NACC -> VPAL, abstract)
LMC	LMC.MM.VTA	Ventral Tegmental Area	inhibitory-gaba	Reward circuit of human brain (NACC -> VTA, abstract)