BrainRegionFAM FT AM CEM

Medial Central Amygdaloid Nucleus

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This page covers biological details of component Medial Central Amygdaloid Nucleus. Region is part of aHuman target integrated biological model.

• Top-down path to region: Forebrain Telencephalon -> Extended Amygdala (FAM.FT.EXTAM) -> Amygdala (FAM.FT.AM) -> Corticomedial Nuclear Complex (FAM.FT.AM.CTM) -> Centromedial Nuclei (FAM.FT.AM.CM) -> Central Amygdala (FAM.FT.AM.CEA) -> Medial Central Amygdaloid Nucleus (FAM.FT.AM.CEM) (see Mind Maps)
• Type: nucleus
• Quality: L0
• Brain area: Forebrain - Affective Motivations Area (FAM)
• Area circuit: Express Fight Emotions (FAMXEFT)
• Role: processor.affective.fight
• Function: mediate behavioral responses, output projections

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Components

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• no child items defined

Connectivity

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Inbound Region Connections:

Source Area	Source Region	Source Name	Type	Role	Reference
FAM	FAM.FT.AM.AB	Accessory Basal Amygdaloid Nucleus	excitatory-glu	uncertain	Summary of the main extra-amygdaloid and intra-amygdaloid connections in the rat (AB -> CE, abstract)
	FAM.FT.AM.BP	Parvicellular Basal Amygdaloid Nucleus	excitatory-glu	uncertain	Amygdala and its network (BLN -> CEA, abstract)
	FAM.FT.AM.CEC	Central Amygdaloid Nucleus, capsular subdivision	excitatory-glu	uncertain	(unknown reference)
	FAM.FT.AM.CEL	Central Amygdaloid Nucleus, lateral subdivision	excitatory-glu	uncertain	(unknown reference)
	FAM.FT.AM.ITC	Intercalated Amygdaloid Nuclei	inhibitory-gaba	uncertain	(unknown reference)
	FAM.FT.AM.MEA	Medial Anterior Amygdaloid Nucleus	excitatory-glu	uncertain	Body alarm system (MED -> CE, abstract)
FEC	FEC.FT.SNC.MED	Substantia Nigra Pars Compacta Medial	modulatory-da	uncertain	(unknown reference)

Outbound Region Connections:

Target Area	Target Region	Target Name	Type	Role	Reference
FAM	FAM.FT.SEP.LT	Lateral Septal Nucleus	excitatory-glu	uncertain	(unknown reference)
LAC	LAC.FD.HT.LTN	Lateral Hypothalamic Nucleus	excitatory-glu	uncertain	Amygdalar disruption of prefrontal cortex (AM -> HT.L, abstract)
	LAC.HL.VGN	Vagus Nucleus	excitatory-glu	uncertain	Amygdala and its network (CEA -> VGDM, abstract)
LMC	LMC.FT.NBM	Basal Nucleus of Meynert	excitatory-glu	uncertain	(unknown reference)
	LMC.HT.LC	Locus Coeruleus	excitatory-glu	uncertain	Amygdalar disruption of prefrontal cortex (AM -> LC, abstract)
	LMC.MM.PAG	Periaqueductal Gray Matter	excitatory-glu	uncertain	Amygdalar disruption of prefrontal cortex (AM -> PAG, abstract)

Thirdparty Circuits

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• Amygdala and its network - see Reference (CF.AM-NET)

BLN=Parvicellular Basal Amygdaloid Nucleus,FAM.FT.AM.BP
CEA=Central Amygdala,FAM.FT.AM.CEA (see Amygdala)
EC=Entorhinal Cortex,FMM.NC.PH.ET (see Rhinal Cortex)
HC=Hippocampus,FMM.FT.HC (see Hippocampal Formation)
HTS=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN
ITC=Inferotemporal Cortex,NSA.NC.IT.TE
LA=Lateral Amygdaloid Nucleus,FAM.FT.AM.LA (see Amygdala)
LHB=Lateral Habenula,FAM.FD.LHB (see Habenula)
MD=Mediodorsal Nucleus of Thalamus,FD.TH.MD (see Cognitive Thalamus)
MPFC=Orbitomedial Prefrontal Cortex,NC.AL.OMPFC
NACC=Accumbens Nucleus,FEC.FT.ACC (see Basal Ganglia)
PAG=Periaqueductal Gray Matter,LMC.MM.PAG
RMTG=Rostromedial Tegmental Nucleus,FEC.HT.TG.RMTG
STC=Wernicke's area A3,NSA.NC.STG.A3
VGDM=Vagus Nucleus,LAC.HL.VGN
VTA=Ventral Tegmental Area,LMC.MM.VTA

• Amygdalar disruption of prefrontal cortex - see Reference (CF.AM-DISRUPTION)

ACG=Anterior Cingulate Cortex,NC.AL.ACG (see Anterior Cingulate Area)
AM=Amygdala,FAM.FT.AM
HC=Hippocampus,FMM.FT.HC (see Hippocampal Formation)
HT.L=Lateral Hypothalamic Area,LAC.FD.HT.LT (see Hypothalamus)
HT.PV=Paraventricular Nucleus,LAC.FD.HT.PV
INS=Insular Cortex,NC.INS
LC=Locus Coeruleus,LMC.HT.LC
MPFC=Orbitofrontal Cortex,NC.AL.OPFC (see Orbitomedial Prefrontal Cortex)
PAG=Periaqueductal Gray Matter,LMC.MM.PAG
PB=Parabrachial Nucleus,LPC.HT.PRF.PB
PUT=Endocrine Glands,TARGET.TEA.ENDOCRINE
SOL=Solitary Nucleus,LPC.HL.SOL
TH=Thalamus,FD.TH

References

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• http://www.surgicalneurologyint.com/article.asp?issn=2152-7806;year=2012;volume=3;issue=2;spage=40;epage=46;aulast=Langevin
• http://neuropolitics.org/defaultmay10.asp