BrainRegionFMM FT HC CA1P
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Proximal CA1 of Hippocampus
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This page covers biological details of component Proximal CA1 of Hippocampus. Region is part of aHuman target integrated biological model.
- Top-down path to region: Forebrain Telencephalon -> Hippocampal Formation (FMM.FT.HF) -> Hippocampus (FMM.FT.HC) -> Ventrolateral Cornu Ammonis of Hippocampus (FMM.FT.HC.CA1) -> Proximal CA1 of Hippocampus (FMM.FT.HC.CA1P) (see Mind Maps)
- Type: cortex
- Quality: L0
- Brain area: Forebrain - Memory Management Area (FMM)
- Area circuit: Spatial Hippocampus (MMAHCS)
- Role: processor.memory.ca1
- Function: Long-term memory, spatial
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Components
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- no child items defined
Connectivity
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Inbound Region Connections:
Outbound Region Connections:
Target Area | Target Region | Target Name | Type | Reference |
FMM | FMM.FD.MB.MMB | Medial Mammillary Nucleus | excitatory-glu | Feeling (HC -> HT, abstract) |
FMM.FT.HF.SUBD | Distal Subiculum | excitatory-glu | Attractor Network in Hippocampus (CA1 -> SUB, abstract) | |
FMM.NC.PH.PAS | Parasubiculum | excitatory-glu | (unknown reference) | |
FMM.NC.PH.POR | Postrhinal Cortex | excitatory-glu | Entorhinal Cortex Inputs and Outputs (CA1 -> TFTH, abstract) | |
NDM | NDM.NC.AL.DMPFC | Dorsomedial Prefrontal Cortex | excitatory-glu | Gating of medial prefrontal activity by the entorhinal cortex (HC -> MPFC, abstract) |
Thirdparty Circuits
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- Medial mammillary nucleus and theta rhythm - see Reference (CT.MMB-THETA)
AVTH=Anteroventral Nucleus,FMM.FD.TH.AV HF=Hippocampal Formation,FMM.FT.HF MMB=Medial Mammillary Nucleus,FMM.FD.MB.MMB RSP=Retrosplenial Cortex,NCP.NC.MPL.RSC SEP=Septal Nuclei,FAM.FT.SEP SupraMM=Supramammillary Nucleus,LAC.FD.HT.SUM VTN=Ventral Tegmental Area,LMC.MM.VTA
- Head Direction Cell Circuit - see Reference (CT.HEAD-DIRECTION)
AD=Anterodorsal Nucleus,FMM.FD.TH.AD DTN=Laterodorsal Tegmental Nucleus,LMC.HT.TG.DTG EC=Entorhinal Cortex,FMM.NC.PH.ET (see Rhinal Cortex) HC=Hippocampus,FMM.FT.HC (see Hippocampal Formation) IPD=Interpeduncular Nucleus,FEC.HT.TG.IPD LD=Lateral Dorsal Nucleus of Thalamus,FMM.FD.TH.LD LHAB=Habenula,FAM.FD.HB LMB=Lateral Mammillary Nucleus,FMM.FD.MB.LMB MVSN=Medial Vestibular Nucleus,LPC.HT.MVBN NPRP=Prepositus Nucleus,LRC.HL.NPH PC=Parietal Lobe,NC.LOBE.PAR PRHC=Postrhinal Cortex,FMM.NC.PH.POR PSUB=Postsubiculum,FMM.NC.PH.POS RSP=Retrosplenial Cortex,NCP.NC.MPL.RSC SUPGEN=Suprageniculate Nucleus of Thalamus,NSA.FD.TH.SG VC=Occipital Lobe,NC.LOBE.OCC
- Entorhinal Cortex Inputs and Outputs - see Reference (CT.ENTORHINAL-CORTEX)
CA1=Ventrolateral Cornu Ammonis of Hippocampus,FMM.FT.HC.CA1 (see Hippocampal Formation) EC=Entorhinal Cortex,FMM.NC.PH.ET (see Rhinal Cortex) TFTH=Postrhinal Cortex,FMM.NC.PH.POR
- Attractor Network in Hippocampus - see Reference (CT.ATTRACTOR-NETWORK)
AN=Anterior Nucleus of Thalamus,FD.TH.AN (see Cognitive Thalamus) CA1=Ventrolateral Cornu Ammonis of Hippocampus,FMM.FT.HC.CA1 (see Hippocampal Formation) CA3=Dorsomedial Cornu Ammonis of Hippocampus,FMM.FT.HC.CA3 (see Hippocampal Formation) DG=Dentate Gyrus,FMM.FT.HC.DG EC=Entorhinal Cortex,FMM.NC.PH.ET (see Rhinal Cortex) MBIN=Medial Mammillary Nucleus,FMM.FD.MB.MMB MBOUT=Lateral Mammillary Nucleus,FMM.FD.MB.LMB NACC=Accumbens Nucleus,FEC.FT.ACC (see Basal Ganglia) PERI=Perirhinal Cortex,FMM.NC.PH.PER PRESUB=Presubiculum,FMM.NC.PH.PRS SEP=Septal Nuclei,FAM.FT.SEP SUB=Subiculum,FMM.FT.HF.SUB (see Hippocampal Formation)
- McNaughton Spatial Processing Network - see Reference (CP.VISUAL-SPATIAL-PROCESSING)
EnthCortex=Entorhinal Cortex,FMM.NC.PH.ET (see Rhinal Cortex) HF=Hippocampal Formation,FMM.FT.HF ITCortex=Inferotemporal Area,NSA.NC.IT PCGRSP=Medial Parietal Lobule,NC.MPL ParInsVestCortex=Ventral Intraparietal Sulcus,NSA.NC.IPS.VIP PosteriorParietalCortex=Caudal Precuneus,NPE.NC.SPL.PG SUB=Subiculum,FMM.FT.HF.SUB (see Hippocampal Formation) SomSensCortex=Primary Somatosensory Cortex,NCP.NC.PG.S1 VisualCortex=Occipital Lobe,NC.LOBE.OCC
- Prefrontal Cortex (PFC) in emotional behavior - see Reference (CF.PFC-EMOTIONS)
ACG=Anterior Cingulate Cortex,NC.AL.ACG (see Anterior Cingulate Area) AM=Amygdala,FAM.FT.AM HCA=Hippocampus,FMM.FT.HC (see Hippocampal Formation) HT=Hypothalamus,FD.HT LPFC=Mid-Dorsolateral Prefrontal Cortex,NDM.NC.AL.DLPFC (see Lateral Prefrontal Cortex) OPFC=Orbitofrontal Cortex,NC.AL.OPFC (see Orbitomedial Prefrontal Cortex) PCA=Medial Parietal Lobule,NC.MPL PN=Pontine Nuclear Complex,HT.PN (see Metencephalic Sensory Nuclei) TH=Mediodorsal Nucleus of Thalamus,FD.TH.MD (see Cognitive Thalamus)
AN=Anterior Nucleus of Thalamus,FD.TH.AN (see Cognitive Thalamus) CG=Posterior Cingulate Cortex,NCP.NC.MPL.PSCG HC=Hippocampus,FMM.FT.HC (see Hippocampal Formation) HT=Hypothalamus,FD.HT
- Gating of medial prefrontal activity by the entorhinal cortex - see Reference (CF.EC-MPFC)
EC=Entorhinal Cortex,FMM.NC.PH.ET (see Rhinal Cortex) HC=Hippocampus,FMM.FT.HC (see Hippocampal Formation) MPFC=Medial Prefrontal Cortex,NC.AL.MPFC (see Orbitomedial Prefrontal Cortex)
- Detailed amygdalohippocampal projections - see Reference (CF.AM-HC-DET)
ABmg=Accessory Basal Amygdaloid Nucleus,FAM.FT.AM.AB Bmg=Magnocellular Basal Amygdaloid Nucleus,FAM.FT.AM.BM Bpc=Parvicellular Basal Amygdaloid Nucleus,FAM.FT.AM.BP CA1D=Distal CA1 of Hippocampus,FMM.FT.HC.CA1D CA1P=Proximal CA1 of Hippocampus,FMM.FT.HC.CA1P L=Lateral Amygdaloid Nucleus,FAM.FT.AM.LA (see Amygdala) PaS=Parasubiculum,FMM.NC.PH.PAS PrS=Presubiculum,FMM.NC.PH.PRS
References
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- http://www.nature.com/nrn/journal/v5/n1/fig_tab/nrn1299_F4.html
- http://www.scholarpedia.org/article/Head_direction_cells
- http://www.sciencedirect.com/science/article/pii/S0149763411001722
- http://learnmem.cshlp.org/content/14/11/714/F1.expansion
- http://www.nature.com/nrn/journal/v3/n2/fig_tab/nrn726_F3.html
- https://www.google.ru/search?hl=rutbo=ptbm=bksq=isbn:0080887988
- http://www.nature.com/nrn/journal/v5/n7
- http://journal.frontiersin.org/article/10.3389/fncom.2011.00001/full
- https://books.google.ru/books?id=P3fSBwAAQBAJ