Revision as of 01:17, 16 June 2015

Decision Making Area

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Local Circuits

(generated)

High-Level Control

unavailable

|| *Component ID* || *Component Name* || *Type* || *Service* || *Function* || *Comments* || || NDM.FD.TH.MDM || Medial Mediodorsal Nucleus of Thalamus || nucleus || NPU || relay emotional attention to orbitofrontal cortex || orbitofrontal cortex (BA12,13) defined by MDm
projection; relay AM-Bp to OFC; OFCm - subjective
pleasantness, OFCl - subjective unpleasantness || || NDM.NC.AL.FPC || Lateral Frontopolar Cortex || cortex, BA 10 || NPU || Emotion Regulation || Frontopolar area, contains ILC - infralimbic cortex ||

Internal Region Connections:*

|| *Source Region* || *Target Region* || *Type* || *Reference* || || NDM.FD.TH.MDM || BrainRegionNDM_NC_AL_FPC NDM.NC.AL.FPC || nucleus-neocortex || [Thalamocortical relationships (MD -> pMD, abstract)] ||

External Inbound Region Connections:*

|| *Source Area* || *Local Region* || *Source Region* || *Source Name* || *Type* || *Reference* || || Cortical || || || || || || || NCP || BrainRegionNDM_NC_AL_FPC NDM.NC.AL.FPC || BrainRegionNCP_NC_INS_PPC NCP.NC.INS.PPC || Peripaleocortical Claustral || neocortex-neocortex || [Amygdalar disruption of prefrontal cortex (INS -> MPFC, abstract)] || || Subcortical || || || || || || || FAM || BrainRegionNDM_FD_TH_MDM NDM.FD.TH.MDM || BrainRegionFAM_FT_AM_AB FAM.FT.AM.AB || Accessory Basal Amygdaloid Nucleus || nucleus-nucleus || [Prefrontal Cortex (PFC) in emotional behavior (AM -> TH, abstract)] || || || || FAM.FT.SEP.MED || Medial Septal Nucleus || nucleus-nucleus-ACh || [Thalamocortical relationships (s1MD -> MD, abstract)] || || FEC || BrainRegionNDM_FD_TH_MDM NDM.FD.TH.MDM || BrainRegionFEC_FT_GPI_RM FEC.FT.GPI.RM || Globus Pallidus Internal Rostromedial || nucleus-nucleus-gaba || [Saccadic Vision (BG -> Thalamus, abstract)] || || FMM || BrainRegionNDM_FD_TH_MDM NDM.FD.TH.MDM || BrainRegionFMM_NC_PH_LEC FMM.NC.PH.LEC || Lateral Entorhinal Cortex || neocortex-nucleus || [Contributions of Diencephalon to Recognition Memory (EC -> MDmc, abstract)] || || || || FMM.NC.PH.PER || Perirhinal Cortex || neocortex-nucleus || [Contributions of Diencephalon to Recognition Memory (Perirhinal -> MDmc, abstract)] || || LMC || BrainRegionNDM_NC_AL_FPC NDM.NC.AL.FPC || BrainRegionLMC_FT_NBM LMC.FT.NBM || Basal Nucleus of Meynert || nucleus-neocortex-ACh || [Physiology and pathophysiology of lower urinary tract (NBM -> MPFC, abstract)] || || || || LMC.MM.VTA || Ventral Tegmental Area || nucleus-neocortex-DA || [Reward circuit of human brain (VTA -> PFC, abstract)] ||

External Outbound Region Connections:*

|| *Target Area* || *Local Region* || *Target Region* || *Target Name* || *Type* || *Reference* || || Cortical || || || || || || || NDM || BrainRegionNDM_FD_TH_MDM NDM.FD.TH.MDM || BrainRegionNDM_NC_AL_DLPFCR NDM.NC.AL.DLPFCR || Rostral Mid-Dorsolateral Prefrontal Cortex || nucleus-neocortex || [Prefrontal Cortex (PFC) in emotional behavior (TH -> LPFC, abstract)] || || || NDM.NC.AL.FPC || BrainRegionNDM_NC_AL_DLPFCR NDM.NC.AL.DLPFCR || Rostral Mid-Dorsolateral Prefrontal Cortex || neocortex-neocortex || [Prefrontal Cortex (PFC) in emotional behavior (OPFC -> LPFC, abstract)] || || || || NDM.NC.AL.VACG || Ventral Anterior Cingulate Area || neocortex-neocortex || [Role for serotonin in moral behavior (OMPFC -> ACG, abstract)] || || Subcortical || || || || || || || FAM || BrainRegionNDM_NC_AL_FPC NDM.NC.AL.FPC || BrainRegionFAM_FT_AM_BM FAM.FT.AM.BM || Magnocellular Basal Amygdaloid Nucleus || neocortex-nucleus || (unknown reference) || || || || FAM.FT.AM.BP || Parvicellular Basal Amygdaloid Nucleus || neocortex-nucleus || (unknown reference) || || || || FAM.FT.SEP.SH || Septohippocampal Nucleus || neocortex-nucleus || (unknown reference) || || FEC || BrainRegionNDM_NC_AL_FPC NDM.NC.AL.FPC || BrainRegionFEC_FT_ACC_CORE FEC.FT.ACC.CORE || Nucleus Accumbens Core || neocortex-nucleus || [Affective basal ganglia circuit (OMPFC -> NACC, abstract)] || || || || FEC.FT.SNR.MED || Substantia Nigra Pars Reticulata Medial || neocortex-nucleus || [Global visual system (FrontalCortex -> BGA, abstract)] || || LAC || BrainRegionNDM_NC_AL_FPC NDM.NC.AL.FPC || BrainRegionLAC_FD_HT_RCH LAC.FD.HT.RCH || Retrochiasmatic Nucleus || neocortex-nucleus || [Prefrontal Cortex (PFC) in emotional behavior (OPFC -> HT, abstract)] ||

High-Level Novelty Attention

unavailable

|| *Component ID* || *Component Name* || *Type* || *Service* || *Function* || *Comments* || || NDM.NC.AL.ROFCL || Lateral Rostral Orbitofrontal Cortex || cortex, BA 12 || NPU || Visual selection of novelty || 12L || || NDM.NC.AL.ROFCM || Medial Rostral Orbitofrontal Cortex || cortex, BA 12 || NPU || Somatosensory selection of novelty || 12M || || NDM.NC.AL.ROFCR || Most Rostral Orbitofrontal Cortex || cortex, BA 12 || NPU || Integral conscious selection of novelty || 12R || || NDM.NC.AL.ROFCS || Sulcal Rostral Orbitofrontal Cortex || cortex, BA 12 || NPU || Gustatory and auditory selection of novelty || 12S ||

Internal Region Connections:*

|| *Source Region* || *Target Region* || *Type* || *Reference* || || NDM.NC.AL.ROFCL || BrainRegionNDM_NC_AL_ROFCR NDM.NC.AL.ROFCR || neocortex-neocortex || [Regulation of Social Brain (MPFC -> OFC, abstract)] || || NDM.NC.AL.ROFCM || BrainRegionNDM_NC_AL_ROFCL NDM.NC.AL.ROFCL || neocortex-neocortex || [Regulation of Social Brain (MPFC -> OFC, abstract)] || || || NDM.NC.AL.ROFCR || neocortex-neocortex || [Regulation of Social Brain (MPFC -> OFC, abstract)] || || NDM.NC.AL.ROFCS || BrainRegionNDM_NC_AL_ROFCL NDM.NC.AL.ROFCL || neocortex-neocortex || [Regulation of Social Brain (MPFC -> OFC, abstract)] ||

External Inbound Region Connections:*

|| *Source Area* || *Local Region* || *Source Region* || *Source Name* || *Type* || *Reference* || || Cortical || || || || || || || NCP || BrainRegionNDM_NC_AL_ROFCR NDM.NC.AL.ROFCR || BrainRegionNCP_NC_MPL_RSC NCP.NC.MPL.RSC || Retrosplenial Cortex || neocortex-neocortex || [Prefrontal Cortex (PFC) in emotional behavior (PCA -> OPFC, abstract)] || || NPE || BrainRegionNDM_NC_AL_ROFCL NDM.NC.AL.ROFCL || BrainRegionNPE_FD_TH_MPV NPE.FD.TH.MPV || Medial Pulvinar || nucleus-neocortex || [Saccadic Vision (Thalamus -> FrontalCortex, abstract)] || || || NDM.NC.AL.ROFCM || BrainRegionNPE_NC_SPL_SA NPE.NC.SPL.SA || Somatosensory Association Cortex || neocortex-neocortex || [Cortico-Cortical Connectivity (SA -> PFC, abstract)] || || NSA || BrainRegionNDM_NC_AL_ROFCS NDM.NC.AL.ROFCS || BrainRegionNSA_NC_PO_PCC NSA.NC.PO.PCC || Precentral Cortex || neocortex-neocortex || [Global visual system (ParietalCortex -> FrontalCortex, abstract)] || || Subcortical || || || || || || || FAM || BrainRegionNDM_NC_AL_ROFCR NDM.NC.AL.ROFCR || BrainRegionFAM_FD_TH_PT FAM.FD.TH.PT || Paratenial Nucleus of Thalamus || nucleus-neocortex || [Saccadic Vision (Thalamus -> FrontalCortex, abstract)] || || FMM || BrainRegionNDM_NC_AL_ROFCR NDM.NC.AL.ROFCR || BrainRegionFMM_FT_HC_CA1D FMM.FT.HC.CA1D || Distal CA1 of Hippocampus || allocortex-neocortex || [Simplified model of hippocampal formation anatomy (CA1 -> mPFC, abstract)] || || || || FMM.FT.HF.SUBD || Distal Subiculum || allocortex-neocortex || [Simplified model of hippocampal formation anatomy (SUB -> mPFC, abstract)] ||

External Outbound Region Connections:*

|| *Target Area* || *Local Region* || *Target Region* || *Target Name* || *Type* || *Reference* || || Cortical || || || || || || || NDM || BrainRegionNDM_NC_AL_ROFCR NDM.NC.AL.ROFCR || BrainRegionNDM_NC_AL_DACG NDM.NC.AL.DACG || Dorsal Anterior Cingulate Area || neocortex-neocortex || [Role for serotonin in moral behavior (OMPFC -> ACG, abstract)] || || || || NDM.NC.AL.IPG || Inferior Prefrontal Gyrus || neocortex-neocortex || [Regulation of Social Brain (OFC -> IFG, abstract)] || || Subcortical || || || || || || || FEC || BrainRegionNDM_NC_AL_ROFCR NDM.NC.AL.ROFCR || BrainRegionFEC_FD_STN_DL FEC.FD.STN.DL || Subthalamic Nucleus Dorsolateral || neocortex-nucleus || (unknown reference) || || || || FEC.FD.TH.RH || Rhomboidal Nucleus of Thalamus || neocortex-nucleus || (unknown reference) || || || || FEC.FT.CN.TL || Caudate Nucleus Tail || neocortex-nucleus || [Global visual system (FrontalCortex -> BGA, abstract)] || || FMM || BrainRegionNDM_NC_AL_ROFCR NDM.NC.AL.ROFCR || BrainRegionFMM_FD_TH_RE FMM.FD.TH.RE || Reuniens Nucleus of Thalamus || neocortex-nucleus || (unknown reference) ||

Working Memory

unavailable

|| *Component ID* || *Component Name* || *Type* || *Service* || *Function* || *Comments* || || NDM.NC.AL.DLPFCL || Lateral Mid-Dorsolateral Prefrontal Cortex || cortex, BA 46 || NPU || Cognitive control related to stimulus processing and selection of relevant
information for behavior || || || NDM.NC.AL.DLPFCR || Rostral Mid-Dorsolateral Prefrontal Cortex || cortex, BA 46 || NPU || Cognitive control and monitoring to resolve conflict in information processing
and competing response plans || ||

Internal Region Connections:*
no connections

External Inbound Region Connections:*

|| *Source Area* || *Local Region* || *Source Region* || *Source Name* || *Type* || *Reference* || || Cortical || || || || || || || NCP || BrainRegionNDM_NC_AL_DLPFCR NDM.NC.AL.DLPFCR || BrainRegionNCP_NC_MPL_RSC NCP.NC.MPL.RSC || Retrosplenial Cortex || neocortex-neocortex || [Prefrontal Cortex (PFC) in emotional behavior (PCA -> LPFC, abstract)] || || NDM || BrainRegionNDM_NC_AL_DLPFCL NDM.NC.AL.DLPFCL || BrainRegionNDM_NC_AL_IPG NDM.NC.AL.IPG || Inferior Prefrontal Gyrus || neocortex-neocortex || [Directed Effort Network (fPole -> DLPFC, abstract)] || || || NDM.NC.AL.DLPFCR || BrainRegionNDM_FD_TH_MDM NDM.FD.TH.MDM || Medial Mediodorsal Nucleus of Thalamus || nucleus-neocortex || [Prefrontal Cortex (PFC) in emotional behavior (TH -> LPFC, abstract)] || || || || NDM.NC.AL.FPC || Lateral Frontopolar Cortex || neocortex-neocortex || [Prefrontal Cortex (PFC) in emotional behavior (OPFC -> LPFC, abstract)] || || NMA || BrainRegionNDM_NC_AL_DLPFCL NDM.NC.AL.DLPFCL || BrainRegionNMA_NC_PMC_F4 NMA.NC.PMC.F4 || Ventral Caudal Premotor Cortex || neocortex-neocortex || [Cortico-Cortical Connectivity (MA -> PFC, abstract)] || || NPE || BrainRegionNDM_NC_AL_DLPFCL NDM.NC.AL.DLPFCL || BrainRegionNPE_FD_TH_MPV NPE.FD.TH.MPV || Medial Pulvinar || nucleus-neocortex || [Saccadic Vision (Thalamus -> FrontalCortex, abstract)] || || || NDM.NC.AL.DLPFCR || BrainRegionNPE_NC_IPL_MST NPE.NC.IPL.MST || Medial Superior Temporal Area || neocortex-neocortex || [Cortico-Cortical Connectivity (PTHA -> PFC, abstract)] || || NSA || BrainRegionNDM_NC_AL_DLPFCL NDM.NC.AL.DLPFCL || BrainRegionNSA_NC_IT_TE NSA.NC.IT.TE || Inferotemporal Cortex || neocortex-neocortex || [3 Visual Cortex Paths (IT -> LPC, abstract)] || || || || NSA.NC.OCC.V2TN || Secondary Visual Cortex, Thin Stripe || neocortex-neocortex || [Cortico-Cortical Connectivity (VA -> PFC, abstract)] || || Subcortical || || || || || || || LLC || BrainRegionNDM_NC_AL_DLPFCL NDM.NC.AL.DLPFCL || BrainRegionLLC_HP_CR_DN LLC.HP.CR.DN || Dentate Nucleus || nucleus-neocortex || [Prefrontal Cortex (PFC) in motor behavior (CR -> LPFC, abstract)] ||

External Outbound Region Connections:*

|| *Target Area* || *Local Region* || *Target Region* || *Target Name* || *Type* || *Reference* || || Cortical || || || || || || || NDM || BrainRegionNDM_NC_AL_DLPFCR NDM.NC.AL.DLPFCR || BrainRegionNDM_NC_AL_DACG NDM.NC.AL.DACG || Dorsal Anterior Cingulate Area || neocortex-neocortex || [Prefrontal Cortex (PFC) in emotional behavior (LPFC -> ACG, abstract)] || || NMA || BrainRegionNDM_NC_AL_DLPFCL NDM.NC.AL.DLPFCL || BrainRegionNMA_FD_TH_VA NMA.FD.TH.VA || Ventral Anterior Nucleus || neocortex-nucleus || [Prefrontal Cortex (PFC) in motor behavior (LPFC -> TH, abstract)] || || || || NMA.NC.PMC.AFEF || Anterior Frontal Eye Field || neocortex-neocortex || [Prefrontal Cortex (PFC) in motor behavior (LPFC -> PMC, abstract)] || || || || NMA.NC.PMC.F5 || Ventral Rostral Premotor Cortex || neocortex-neocortex || [Prefrontal Cortex (PFC) in motor behavior (LPFC -> PMC, abstract)] || || || NDM.NC.AL.DLPFCR || BrainRegionNMA_NC_PMC_F7 NMA.NC.PMC.F7 || Dorsal Rostral Premotor Cortex || neocortex-neocortex || [Prefrontal Cortex (PFC) in motor behavior (LPFC -> PMC, abstract)] || || || || NMA.NC.SMC.SEF || Supplementary Eye Field || neocortex-neocortex || [3 Visual Cortex Paths (LPC -> pre-SMA, abstract)] || || Subcortical || || || || || || || FEC || BrainRegionNDM_NC_AL_DLPFCL NDM.NC.AL.DLPFCL || BrainRegionFEC_FT_CN_HD FEC.FT.CN.HD || Caudate Nucleus Head || neocortex-nucleus || [Global visual system (FrontalCortex -> BGA, abstract)] ||

Motivatory Associations

unavailable

|| *Component ID* || *Component Name* || *Type* || *Service* || *Function* || *Comments* || || NDM.FD.TH.SM || Submedial Nucleus of Thalamus || nucleus || NPU || Pain center || Projections from SC Lamina I, trigeminal nucleus to
ACC || || NDM.NC.AL.DMPFC || Dorsomedial Prefrontal Cortex || cortex, BA 09 || NPU || Ongoing Extroverted Attention to Select Appropriate Response || upper MPFC, primary connections to the cingulate
and the motor and premotor cortices || || NDM.NC.AL.IPG || Inferior Prefrontal Gyrus || cortex, BA 47 || NPU || Processing of syntax in oral and sign languages || Personality, endurance || || NDM.NC.AL.VMPFC || Ventromedial Prefrontal Cortex || cortex, BA 11 || NPU || Ongoing Introverted Attention with Regard to Emotions and Feelings, Reward or
Punishment || lower MPFC, primary connections to limbic and
sensory cortices; Reward mediated behaviours ||

Internal Region Connections:*

|| *Source Region* || *Target Region* || *Type* || *Reference* || || NDM.FD.TH.SM || BrainRegionNDM_NC_AL_DMPFC NDM.NC.AL.DMPFC || nucleus-neocortex || [Saccadic Vision (Thalamus -> FrontalCortex, abstract)] || || NDM.NC.AL.IPG || BrainRegionNDM_NC_AL_DMPFC NDM.NC.AL.DMPFC || neocortex-neocortex || (unknown reference) ||

External Inbound Region Connections:*

|| *Source Area* || *Local Region* || *Source Region* || *Source Name* || *Type* || *Reference* || || Cortical || || || || || || || NCP || BrainRegionNDM_NC_AL_IPG NDM.NC.AL.IPG || BrainRegionNCP_NC_INS_AIC NCP.NC.INS.AIC || Anterior Insular Cortex || neocortex-neocortex || [Directed Effort Network (Insula -> fPole, abstract)] || || || || NCP.NC.TPC || Temporopolar Cortex || neocortex-neocortex || [Language-Related Regions (TC -> vIFC)] || || NDM || BrainRegionNDM_NC_AL_IPG NDM.NC.AL.IPG || BrainRegionNDM_NC_AL_ROFCR NDM.NC.AL.ROFCR || Most Rostral Orbitofrontal Cortex || neocortex-neocortex || [Regulation of Social Brain (OFC -> IFG, abstract)] || || Subcortical || || || || || || || FAM || BrainRegionNDM_NC_AL_VMPFC NDM.NC.AL.VMPFC || BrainRegionFAM_FT_SEP_DBB FAM.FT.SEP.DBB || Diagonal Band of Broca || nucleus-neocortex-gaba || (unknown reference) || || LPC || BrainRegionNDM_FD_TH_SM NDM.FD.TH.SM || BrainRegionLPC_SC_PH_LMG LPC.SC.PH.LMG || Lower Marginal Nucleus || nucleus-nucleus || (unknown reference) || || || || LPC.SC.PH.UMG || Upper Marginal Nucleus || nucleus-nucleus || (unknown reference) || || || NDM.NC.AL.VMPFC || BrainRegionLPC_FD_TH_PV LPC.FD.TH.PV || Paraventricular Nucleus of Thalamus || nucleus-neocortex || [Saccadic Vision (Thalamus -> FrontalCortex, abstract)] ||

External Outbound Region Connections:*

|| *Target Area* || *Local Region* || *Target Region* || *Target Name* || *Type* || *Reference* || || Cortical || || || || || || || NDM || BrainRegionNDM_NC_AL_DMPFC NDM.NC.AL.DMPFC || BrainRegionNDM_NC_AL_DACG NDM.NC.AL.DACG || Dorsal Anterior Cingulate Area || neocortex-neocortex || (unknown reference) || || || NDM.NC.AL.IPG || BrainRegionNDM_NC_AL_DLPFCL NDM.NC.AL.DLPFCL || Lateral Mid-Dorsolateral Prefrontal Cortex || neocortex-neocortex || [Directed Effort Network (fPole -> DLPFC, abstract)] || || || || NDM.NC.AL.VACG || Ventral Anterior Cingulate Area || neocortex-neocortex || [Directed Effort Network (fPole -> vACC)] || || Subcortical || || || || || || || FAM || BrainRegionNDM_NC_AL_DMPFC NDM.NC.AL.DMPFC || BrainRegionFAM_FT_AM_ITC FAM.FT.AM.ITC || Intercalated Amygdaloid Nuclei || neocortex-nucleus || (unknown reference) ||

Motivational Responses

unavailable

|| *Component ID* || *Component Name* || *Type* || *Service* || *Function* || *Comments* || || NDM.NC.AL.DMCG || Dorsal Anterior Cingulate Area || cortex, BA 32 || NPU || Rational Thought Processes || Anticipate and detect targets, indicate novelty,
influence motor responses, encode reward values,
and signal errors, motor, attentional and cognitive
functions; BA32-caudal || || NDM.NC.AL.PGCG || Pregenual Cingulate Cortex || cortex, BA 33 || NPU || Sensation of Emotion || Storage of emotional memory, emotions, mood and
autonomic functions || || NDM.NC.AL.VMCG || Ventral Anterior Cingulate Area || cortex, BA 24 || NPU || Response Selection || BA24-caudal ||

Internal Region Connections:*
no connections

External Inbound Region Connections:*
no connections

External Outbound Region Connections:*
no connections

Unimodal Control

unavailable

|| *Component ID* || *Component Name* || *Type* || *Service* || *Function* || *Comments* || || NDM.NC.AL.DACG || Dorsal Anterior Cingulate Area || cortex, BA 32 || NPU || Rational Thought Processes || Anticipate and detect targets, indicate novelty,
influence motor responses, encode reward values,
and signal errors, motor, attentional and cognitive
functions; BA32-rostral || || NDM.NC.AL.VACG || Ventral Anterior Cingulate Area || cortex, BA 24 || NPU || Seat of Free Will || motor, attentional and cognitive functions;
BA24-rostral ||