Difference between revisions of "BrainRegionLMC HT LC"

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|  || [[BrainRegionFAM_FT_BNST|FAM.FT.BNST]] || Bed Nucleus of Stria Terminalis || excitatory-glu || (unknown reference)
 
|  || [[BrainRegionFAM_FT_BNST|FAM.FT.BNST]] || Bed Nucleus of Stria Terminalis || excitatory-glu || (unknown reference)
 
|-
 
|-
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| [[BrainAreaLAC|LAC]] || [[BrainRegionLAC_FD_HT_DM|LAC.FD.HT.DM]] || Dorsomedial Hypothalamic Nucleus || excitatory-glu || (unknown reference)
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| [[BrainAreaLAC|LAC]] || [[BrainRegionLAC_FD_HT_DM|LAC.FD.HT.DM]] || Dorsomedial Hypothalamic Nucleus || excitatory-glu || [http://journal.frontiersin.org/article/10.3389/fnint.2012.00094/full Effect of light on pupil diameter (DMH -> LC)]
 
|-
 
|-
 
|  || [[BrainRegionLAC_FD_HT_TBM|LAC.FD.HT.TBM]] || Tuberomammillary Nucleus || excitatory-glu || (unknown reference)
 
|  || [[BrainRegionLAC_FD_HT_TBM|LAC.FD.HT.TBM]] || Tuberomammillary Nucleus || excitatory-glu || (unknown reference)
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|-
 
|-
 
| [[BrainAreaLAC|LAC]] || [[BrainRegionLAC_FD_HT_PO|LAC.FD.HT.PO]] || Preoptic Nucleus || modulatory-ne || [http://www.nature.com/neuro/journal/v5/n10/fig_tab/nn913_F1.html Simplified NREM sleep-promoting pathway (LC -> VLPO)]
 
| [[BrainAreaLAC|LAC]] || [[BrainRegionLAC_FD_HT_PO|LAC.FD.HT.PO]] || Preoptic Nucleus || modulatory-ne || [http://www.nature.com/neuro/journal/v5/n10/fig_tab/nn913_F1.html Simplified NREM sleep-promoting pathway (LC -> VLPO)]
 +
|-
 +
|  || [[BrainRegionLAC_SC_IZ_CSC|LAC.SC.IZ.CSC]] || Ciliospinal Center || modulatory-ne || [http://journal.frontiersin.org/article/10.3389/fnint.2012.00094/full Effect of light on pupil diameter (LC -> IML)]
 
|-
 
|-
 
|  || [[BrainRegionLAC_SC_IZ_IML|LAC.SC.IZ.IML]] || Intermediolateral Nucleus || modulatory-ne || [http://www.intechopen.com/books/computational-intelligence-in-electromyography-analysis-a-perspective-on-current-applications-and-future-challenges/sphincter-emg-for-diagnosing-multiple-system-atrophy-and-related-disorders Physiology and pathophysiology of lower urinary tract (LC -> IML)]
 
|  || [[BrainRegionLAC_SC_IZ_IML|LAC.SC.IZ.IML]] || Intermediolateral Nucleus || modulatory-ne || [http://www.intechopen.com/books/computational-intelligence-in-electromyography-analysis-a-perspective-on-current-applications-and-future-challenges/sphincter-emg-for-diagnosing-multiple-system-atrophy-and-related-disorders Physiology and pathophysiology of lower urinary tract (LC -> IML)]
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= Thirdparty Circuits =
 
= Thirdparty Circuits =
 
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* [http://www.frontiersin.org/files/Articles/31465/fnint-06-00094-r2/image_m/fnint-06-00094-g002.jpg Effect of light on pupil diameter] - see [http://journal.frontiersin.org/article/10.3389/fnint.2012.00094/full Reference]
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<img src="http://www.frontiersin.org/files/Articles/31465/fnint-06-00094-r2/image_m/fnint-06-00094-g002.jpg" alt="unavailable" style="max-width: 100%;">
  
 
* [http://www.intechopen.com/source/html/40109/media/image1.jpeg Physiology and pathophysiology of lower urinary tract] - see [http://www.intechopen.com/books/computational-intelligence-in-electromyography-analysis-a-perspective-on-current-applications-and-future-challenges/sphincter-emg-for-diagnosing-multiple-system-atrophy-and-related-disorders Reference]
 
* [http://www.intechopen.com/source/html/40109/media/image1.jpeg Physiology and pathophysiology of lower urinary tract] - see [http://www.intechopen.com/books/computational-intelligence-in-electromyography-analysis-a-perspective-on-current-applications-and-future-challenges/sphincter-emg-for-diagnosing-multiple-system-atrophy-and-related-disorders Reference]
  
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<img src="http://www.intechopen.com/source/html/40109/media/image1.jpeg" alt="unavailable">
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<img src="http://www.intechopen.com/source/html/40109/media/image1.jpeg" alt="unavailable" style="max-width: 100%;">
  
 
* [http://www.nature.com/nrn/journal/v11/n6/images/nrn2849-f7.jpg Contribution of nAChR subunits to nicotine withdrawal symptoms] - see [http://www.nature.com/nrn/journal/v11/n6/fig_tab/nrn2849_F7.html Reference]
 
* [http://www.nature.com/nrn/journal/v11/n6/images/nrn2849-f7.jpg Contribution of nAChR subunits to nicotine withdrawal symptoms] - see [http://www.nature.com/nrn/journal/v11/n6/fig_tab/nrn2849_F7.html Reference]
  
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<img src="http://www.nature.com/nrn/journal/v11/n6/images/nrn2849-f7.jpg" alt="unavailable">
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<img src="http://www.nature.com/nrn/journal/v11/n6/images/nrn2849-f7.jpg" alt="unavailable" style="max-width: 100%;">
  
 
* [http://www.nature.com/neuro/journal/v5/n10/images/nn913-F1.jpg Simplified NREM sleep-promoting pathway] - see [http://www.nature.com/neuro/journal/v5/n10/fig_tab/nn913_F1.html Reference]
 
* [http://www.nature.com/neuro/journal/v5/n10/images/nn913-F1.jpg Simplified NREM sleep-promoting pathway] - see [http://www.nature.com/neuro/journal/v5/n10/fig_tab/nn913_F1.html Reference]
  
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<img src="http://www.nature.com/neuro/journal/v5/n10/images/nn913-F1.jpg" alt="unavailable">
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<img src="http://www.nature.com/neuro/journal/v5/n10/images/nn913-F1.jpg" alt="unavailable" style="max-width: 100%;">
  
 
* [http://neuropolitics.org/connect-amygdala.jpg Amygdalar disruption of prefrontal cortex] - see [http://neuropolitics.org/defaultmay10.asp Reference]
 
* [http://neuropolitics.org/connect-amygdala.jpg Amygdalar disruption of prefrontal cortex] - see [http://neuropolitics.org/defaultmay10.asp Reference]
  
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<img src="http://neuropolitics.org/connect-amygdala.jpg" alt="unavailable">
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* http://journal.frontiersin.org/article/10.3389/fnint.2012.00094/full
 
* http://www.intechopen.com/books/computational-intelligence-in-electromyography-analysis-a-perspective-on-current-applications-and-future-challenges/sphincter-emg-for-diagnosing-multiple-system-atrophy-and-related-disorders
 
* http://www.intechopen.com/books/computational-intelligence-in-electromyography-analysis-a-perspective-on-current-applications-and-future-challenges/sphincter-emg-for-diagnosing-multiple-system-atrophy-and-related-disorders
 
* http://www.nature.com/nrn/journal/v11/n6/fig_tab/nrn2849_F7.html
 
* http://www.nature.com/nrn/journal/v11/n6/fig_tab/nrn2849_F7.html
 
* http://www.nature.com/neuro/journal/v5/n10/fig_tab/nn913_F1.html
 
* http://www.nature.com/neuro/journal/v5/n10/fig_tab/nn913_F1.html
 
* http://neuropolitics.org/defaultmay10.asp
 
* http://neuropolitics.org/defaultmay10.asp

Revision as of 09:07, 7 September 2015

Locus Coeruleus

@@Home -> BiologicalLifeResearch -> BrainAreaLMC -> BrainRegionLMC_HT_LC

This page covers biological details of component Locus Coeruleus. Region is part of aHuman target integrated biological model.

  • Top-down path to region: Hindbrain Metencephalon -> Locus Coeruleus (LMC.HT.LC) (see Mind Maps)
  • Type: nucleus
  • Brain area: Lower Brain - Modulatory Contol Area
  • Role: relay
  • Function: Regulate the intensity of responses to salient stimuli
  • Notes to function: NE Source, enhance signal-to-noise ratio, suppressing irrelevant stimuli (lateral inhibition); inhibitory nucleus

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Components

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Connectivity

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LMC.HT.LC.dot.png

Inbound Region Connections:

Source Area Source Region Source Name Type Reference
FAM FAM.FT.AM.CEM Medial Central Amygdaloid Nucleus excitatory-glu Amygdalar disruption of prefrontal cortex (AM -> LC, abstract)
FAM.FT.BNST Bed Nucleus of Stria Terminalis excitatory-glu (unknown reference)
LAC LAC.FD.HT.DM Dorsomedial Hypothalamic Nucleus excitatory-glu Effect of light on pupil diameter (DMH -> LC)
LAC.FD.HT.TBM Tuberomammillary Nucleus excitatory-glu (unknown reference)
LRC LRC.HL.RF.MED Central Medullary Reticular Nucleus excitatory-glu (unknown reference)
NDM NDM.NC.AL.VACG Ventral Anterior Cingulate Area excitatory-glu (unknown reference)

Outbound Region Connections:

Target Area Target Region Target Name Type Reference
FAM FAM.FD.LHB.LT Lateral Habenula Lateral Part modulatory-ne Contribution of nAChR subunits to nicotine withdrawal symptoms (LC -> LHB, abstract)
FAM.FD.LHB.MED Lateral Habenula Medial Part modulatory-ne Contribution of nAChR subunits to nicotine withdrawal symptoms (LC -> LHB, abstract)
FAM.FD.MHB Medial Habenula modulatory-ne Contribution of nAChR subunits to nicotine withdrawal symptoms (LC -> MHB)
FAM.FT.SEP.DBB Diagonal Band of Broca modulatory-ne (unknown reference)
FEC FEC.FT.SNC.MED Substantia Nigra Pars Compacta Medial modulatory-ne (unknown reference)
FEC.HT.PPN.IPD Interpeduncular Nucleus modulatory-ne Contribution of nAChR subunits to nicotine withdrawal symptoms (LC -> IPN)
LAC LAC.FD.HT.PO Preoptic Nucleus modulatory-ne Simplified NREM sleep-promoting pathway (LC -> VLPO)
LAC.SC.IZ.CSC Ciliospinal Center modulatory-ne Effect of light on pupil diameter (LC -> IML)
LAC.SC.IZ.IML Intermediolateral Nucleus modulatory-ne Physiology and pathophysiology of lower urinary tract (LC -> IML)

Thirdparty Circuits

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References

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