Difference between revisions of "BrainRegionNPE NC PMC AFEF"
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<pre style="color: green">Anterior Frontal Eye Field</pre> | <pre style="color: green">Anterior Frontal Eye Field</pre> | ||
@@[[Home]] -> [[BiologicalLifeResearch]] -> [[BrainAreaNPE]] -> [[BrainRegionNPE_NC_PMC_AFEF]] | @@[[Home]] -> [[BiologicalLifeResearch]] -> [[BrainAreaNPE]] -> [[BrainRegionNPE_NC_PMC_AFEF]] | ||
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* '''Top-down path to region''': Cerebral Cortex -> Anterior Lobe (NC.LOBE.ANT) -> [[BrainCenterNC_PMC|Premotor Cortex]] (NC.PMC) -> Frontal Eye Field (NMA.NC.PMC.FEF) -> [[BrainRegionNPE_NC_PMC_AFEF|Anterior Frontal Eye Field]] (NPE.NC.PMC.AFEF) (see [[OverallMindMaps|Mind Maps]]) | * '''Top-down path to region''': Cerebral Cortex -> Anterior Lobe (NC.LOBE.ANT) -> [[BrainCenterNC_PMC|Premotor Cortex]] (NC.PMC) -> Frontal Eye Field (NMA.NC.PMC.FEF) -> [[BrainRegionNPE_NC_PMC_AFEF|Anterior Frontal Eye Field]] (NPE.NC.PMC.AFEF) (see [[OverallMindMaps|Mind Maps]]) | ||
* '''Type''': cortex | * '''Type''': cortex | ||
− | * '''Brain area''': [[BrainAreaNPE|Neocortical Brain - Unimodal Execution Area]] | + | * '''Quality''': L0 |
+ | * '''Brain area''': [[BrainAreaNPE|Neocortical Brain - Unimodal Execution Area]] (NPE) | ||
+ | * '''Area circuit''': Cortical Vision Control (CVC) | ||
* '''Brodmann ID''': 08 | * '''Brodmann ID''': 08 | ||
* '''Role''': cortex.generic | * '''Role''': cortex.generic | ||
* '''Function''': Head and eye movements toward auditory stimuli | * '''Function''': Head and eye movements toward auditory stimuli | ||
− | * '''Notes to function''': longer saccades, dorsomedial - 8A (8Ac, 8Am), but not 8Ar | + | * '''Notes to function''': |
+ | ** longer saccades, dorsomedial - 8A (8Ac, 8Am), but not 8Ar | ||
+ | ** 8Ac - saccades | ||
(generated) | (generated) | ||
= Components = | = Components = | ||
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{| class=wikitable width=80% | {| class=wikitable width=80% | ||
− | | '''Source Area''' || '''Source Region''' || '''Source Name''' || '''Type''' || '''Reference''' | + | | '''Source Area''' || '''Source Region''' || '''Source Name''' || '''Type''' || '''Role''' || '''Reference''' |
|- | |- | ||
− | | [[BrainAreaNDM|NDM]] || [[BrainRegionNDM_NC_AL_DLPFCL|NDM.NC.AL.DLPFCL]] || Lateral Mid-Dorsolateral Prefrontal Cortex || feedforward-glu || [https://www.google.ru/search?hl=rutbo=ptbm=bksq=isbn:0080887988 Prefrontal Cortex (PFC) in motor behavior (LPFC -> PMC, abstract)] | + | | [[BrainAreaNDM|NDM]] || [[BrainRegionNDM_NC_AL_DLPFCL|NDM.NC.AL.DLPFCL]] || Lateral Mid-Dorsolateral Prefrontal Cortex || feedforward-glu || uncertain ||[https://www.google.ru/search?hl=rutbo=ptbm=bksq=isbn:0080887988 Prefrontal Cortex (PFC) in motor behavior (LPFC -> PMC, abstract)] |
|- | |- | ||
− | | [[BrainAreaNMA|NMA]] || [[BrainRegionNMA_FD_TH_MDL|NMA.FD.TH.MDL]] || Lateral Mediodorsal Nucleus of Thalamus || excitatory-glu || [http://www.springerimages.com/Images/LifeSciences/1-10.1007_s00359-004-0565-9-0 Oculomotor decision-making (Thalamus -> FEF, abstract)] | + | | [[BrainAreaNMA|NMA]] || [[BrainRegionNMA_FD_TH_MDL|NMA.FD.TH.MDL]] || Lateral Mediodorsal Nucleus of Thalamus || excitatory-glu || uncertain ||[http://www.springerimages.com/Images/LifeSciences/1-10.1007_s00359-004-0565-9-0 Oculomotor decision-making (Thalamus -> FEF, abstract)] |
|- | |- | ||
− | | [[BrainAreaNPE|NPE]] || [[BrainRegionNPE_NC_BRA_PO|NPE.NC.BRA.PO]] || Broca's Area Pars Opercularis || feedforward-glu || [http://www.nature.com/neuro/journal/v12/n6/fig_tab/nn.2331_F5.html Cortical Auditory System (IFC44 -> PMC8, abstract)] | + | | [[BrainAreaNPE|NPE]] || [[BrainRegionNPE_NC_BRA_PO|NPE.NC.BRA.PO]] || Broca's Area Pars Opercularis || feedforward-glu || uncertain ||[http://www.nature.com/neuro/journal/v12/n6/fig_tab/nn.2331_F5.html Cortical Auditory System (IFC44 -> PMC8, abstract)] |
|- | |- | ||
− | | || [[BrainRegionNPE_NC_PMC_CFEF|NPE.NC.PMC.CFEF]] || Caudal Frontal Eye Field || feedforward-glu || (unknown reference) | + | | || [[BrainRegionNPE_NC_PMC_CFEF|NPE.NC.PMC.CFEF]] || Caudal Frontal Eye Field || feedforward-glu || uncertain ||(unknown reference) |
|- | |- | ||
− | | || [[BrainRegionNPE_NC_SMC_SEF|NPE.NC.SMC.SEF]] || Supplementary Eye Field || feedforward-glu || [http://www.cixip.com/index.php/page/content/id/1190 Summary of eye movement control (SEF -> FEF, abstract)] | + | | || [[BrainRegionNPE_NC_SMC_SEF|NPE.NC.SMC.SEF]] || Supplementary Eye Field || feedforward-glu || uncertain ||[http://www.cixip.com/index.php/page/content/id/1190 Summary of eye movement control (SEF -> FEF, abstract)] |
|} | |} | ||
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{| class=wikitable width=80% | {| class=wikitable width=80% | ||
− | | '''Target Area''' || '''Target Region''' || '''Target Name''' || '''Type''' || '''Reference''' | + | | '''Target Area''' || '''Target Region''' || '''Target Name''' || '''Type''' || '''Role''' || '''Reference''' |
|- | |- | ||
− | | [[BrainAreaFEC|FEC]] || [[BrainRegionFEC_FD_STN_MED|FEC.FD.STN.MED]] || Subthalamic Nucleus Medial || excitatory-glu || [http://www.neurology.org/content/70/21/1991/F2.expansion.html Functional subdivisions of the subthalamic nucleus (FEF -> STN, abstract)] | + | | [[BrainAreaFEC|FEC]] || [[BrainRegionFEC_FD_STN_MED|FEC.FD.STN.MED]] || Subthalamic Nucleus Medial || excitatory-glu || uncertain || [http://www.neurology.org/content/70/21/1991/F2.expansion.html Functional subdivisions of the subthalamic nucleus (FEF -> STN, abstract)] |
|- | |- | ||
− | | || [[BrainRegionFEC_FT_CN_BD|FEC.FT.CN.BD]] || Caudate Nucleus Body || excitatory-glu || [http://www.sciencedirect.com/science/article/pii/S0959438808001566 Global visual system (FrontalCortex -> BGA, abstract)] | + | | || [[BrainRegionFEC_FT_CN_BD|FEC.FT.CN.BD]] || Caudate Nucleus Body || excitatory-glu || uncertain || [http://www.sciencedirect.com/science/article/pii/S0959438808001566 Global visual system (FrontalCortex -> BGA, abstract)] |
|- | |- | ||
− | | [[BrainAreaLRC|LRC]] || [[BrainRegionLRC_HL_PRF_GCR|LRC.HL.PRF.GCR]] || Gigantocellular Reticular Nucleus || excitatory-glu || [http://openagrosrl.com/www/page/292/ Motor neurons control (CTX -> MRF, abstract)] | + | | [[BrainAreaLRC|LRC]] || [[BrainRegionLRC_HL_PRF_GCR|LRC.HL.PRF.GCR]] || Gigantocellular Reticular Nucleus || excitatory-glu || uncertain || [http://openagrosrl.com/www/page/292/ Motor neurons control (CTX -> MRF, abstract)] |
|- | |- | ||
− | | || [[BrainRegionLRC_HT_PRF_RPO|LRC.HT.PRF.RPO]] || Oral Pontine Reticular Nucleus || excitatory-glu || [http://openagrosrl.com/www/page/292/ Motor neurons control (CTX -> PRF, abstract)] | + | | || [[BrainRegionLRC_HT_PRF_RPO|LRC.HT.PRF.RPO]] || Oral Pontine Reticular Nucleus || excitatory-glu || uncertain || [http://openagrosrl.com/www/page/292/ Motor neurons control (CTX -> PRF, abstract)] |
|- | |- | ||
− | | || [[BrainRegionLRC_MM_CJ|LRC.MM.CJ]] || Cajal Nucleus || excitatory-glu || [http://www.cixip.com/index.php/page/content/id/1190 Summary of eye movement control (FEF -> riMLF, abstract)] | + | | || [[BrainRegionLRC_MM_CJ|LRC.MM.CJ]] || Cajal Nucleus || excitatory-glu || uncertain || [http://www.cixip.com/index.php/page/content/id/1190 Summary of eye movement control (FEF -> riMLF, abstract)] |
|- | |- | ||
− | | || [[BrainRegionLRC_MM_DSCH|LRC.MM.DSCH]] || Darkschewitsch Nucleus || excitatory-glu || (unknown reference) | + | | || [[BrainRegionLRC_MM_DSCH|LRC.MM.DSCH]] || Darkschewitsch Nucleus || excitatory-glu || uncertain || (unknown reference) |
|- | |- | ||
− | | || [[BrainRegionLRC_MM_SC_INT|LRC.MM.SC.INT]] || Intermediate Superior Colliculus || excitatory-glu || [http://www.cixip.com/index.php/page/content/id/1190 Summary of eye movement control (FEF -> SC, abstract)] | + | | || [[BrainRegionLRC_MM_SC_INT|LRC.MM.SC.INT]] || Intermediate Superior Colliculus || excitatory-glu || uncertain || [http://www.cixip.com/index.php/page/content/id/1190 Summary of eye movement control (FEF -> SC, abstract)] |
|- | |- | ||
− | | [[BrainAreaNMA|NMA]] || [[BrainRegionNMA_NC_PMC_F5|NMA.NC.PMC.F5]] || Ventral Rostral Premotor Cortex || feedforward-glu || [http://www.nature.com/neuro/journal/v12/n6/fig_tab/nn.2331_F5.html Cortical Auditory System (PMC8 -> PMC6, abstract)] | + | | [[BrainAreaNMA|NMA]] || [[BrainRegionNMA_NC_PMC_F5|NMA.NC.PMC.F5]] || Ventral Rostral Premotor Cortex || feedforward-glu || uncertain || [http://www.nature.com/neuro/journal/v12/n6/fig_tab/nn.2331_F5.html Cortical Auditory System (PMC8 -> PMC6, abstract)] |
|- | |- | ||
− | | || [[BrainRegionNMA_NC_PMC_F7|NMA.NC.PMC.F7]] || Dorsal Rostral Premotor Cortex || feedforward-glu || (unknown reference) | + | | || [[BrainRegionNMA_NC_PMC_F7|NMA.NC.PMC.F7]] || Dorsal Rostral Premotor Cortex || feedforward-glu || uncertain || (unknown reference) |
|} | |} | ||
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(generated) | (generated) | ||
− | * [http://ars.els-cdn.com/content/image/1-s2.0-S0959438808001566-gr1.jpg Global visual system] - see [http://www.sciencedirect.com/science/article/pii/S0959438808001566 Reference] | + | * [http://ars.els-cdn.com/content/image/1-s2.0-S0959438808001566-gr1.jpg Global visual system] - see [http://www.sciencedirect.com/science/article/pii/S0959438808001566 Reference] (CP.GLOBAL-VISUAL-SYSTEM) |
− | <img src="http:// | + | ATH=Anterior Nucleus of Thalamus,FD.TH.AN (see [[BrainCenterFD_TH_CR|Cognitive Thalamus]]) |
+ | BGA=[[BrainCenterFEC_FT_BG|Basal Ganglia,FEC.FT.BG]] | ||
+ | FrontalCortex=Anterior Lobe,NC.LOBE.ANT | ||
+ | LGN=[[BrainRegionNSA_FD_LGN|Lateral Geniculate Nucleus,NSA.FD.LGN]] | ||
+ | OPN=[[BrainRegionLPC_MM_OCN|Oculomotor Nucleus,LPC.MM.OCN]] | ||
+ | ParietalCortex=Parietal Lobe,NC.LOBE.PAR | ||
+ | Pulvinar=Pulvinar,FD.PV (see [[BrainCenterFD_TH_SR|Sensory Thalamus]]) | ||
+ | RF=[[BrainCenterHT_RF|Pontine Reticular Formation,HT.RF]] | ||
+ | Retina=[[BrainRegionLPC_FD_RT|Retinal Nucleus,LPC.FD.RT]] | ||
+ | SCi=Superior Colliculus,MM.SC (see [[BrainCenterMM_REF|Reflexes Nuclei of Midbrain Mesencephalon]]) | ||
+ | SCs=Superior Colliculus,MM.SC (see [[BrainCenterMM_REF|Reflexes Nuclei of Midbrain Mesencephalon]]) | ||
+ | SNc=[[BrainRegionFEC_FT_SNC_LT|Substantia Nigra Pars Compacta Lateral,FEC.FT.SNC.LT]] | ||
+ | SNr=[[BrainRegionFEC_FT_SNR_DL|Substantia Nigra Pars Reticulata Dorsolateral,FEC.FT.SNR.DL]] | ||
+ | SpinalCord=Lamina IX,SC.VH.L9 (see [[BrainCenterSC_VH|Anterior/Ventral Horn]]) | ||
+ | Striatum=Striatum,FEC.FT.ST (see [[BrainCenterFEC_FT_BG|Basal Ganglia]]) | ||
+ | VisualCortex=[[BrainCenterNC_LOBE_OCC|Occipital Lobe,NC.LOBE.OCC]] | ||
+ | <img src="http://ahuman.org/svn/ahwiki/images/ext/7192d7e1c7041f25a6eddc32c4f67e91.jpg" alt=alt="unavailable" style="max-width: 100%;"> | ||
− | * [http://www.cixip.com/Public/kindeditor/attached/image/20121030/20121030134649_52795.jpg Summary of eye movement control] - see [http://www.cixip.com/index.php/page/content/id/1190 Reference] | + | * [http://www.cixip.com/Public/kindeditor/attached/image/20121030/20121030134649_52795.jpg Summary of eye movement control] - see [http://www.cixip.com/index.php/page/content/id/1190 Reference] (CP.EYE-FIELDS) |
− | <img src="http:// | + | DLPFC=Mid-Dorsolateral Prefrontal Cortex,NDM.NC.AL.DLPFC (see [[BrainCenterNC_AL_LPFC|Lateral Prefrontal Cortex]]) |
+ | FEF=Frontal Eye Field,NMA.NC.PMC.FEF (see [[BrainCenterNC_PMC|Premotor Cortex]]) | ||
+ | PEF=Posterior Eye Field,NPE.NC.IPS.PEF (see [[BrainCenterNSA_NC_IPS|Intraparietal Sulcus]]) | ||
+ | PPRF=Paramedian Pontine Reticular Formation,HT.PRF.PPRF (see [[BrainCenterHT_RF|Pontine Reticular Formation]]) | ||
+ | SC=Superior Colliculus,MM.SC (see [[BrainCenterMM_REF|Reflexes Nuclei of Midbrain Mesencephalon]]) | ||
+ | SEF=[[BrainRegionNPE_NC_SMC_SEF|Supplementary Eye Field,NPE.NC.SMC.SEF]] | ||
+ | riMLF=[[BrainRegionLRC_MM_CJ|Cajal Nucleus,LRC.MM.CJ]] | ||
+ | <img src="http://ahuman.org/svn/ahwiki/images/ext/1e34c15be19f98dbf300ca306c8f4c53.jpg" alt=alt="unavailable" style="max-width: 100%;"> | ||
− | * [http://www.nature.com/neuro/journal/v12/n6/images/nn.2331-F5.jpg Cortical Auditory System] - see [http://www.nature.com/neuro/journal/v12/n6/fig_tab/nn.2331_F5.html Reference] | + | * [http://www.nature.com/neuro/journal/v12/n6/images/nn.2331-F5.jpg Cortical Auditory System] - see [http://www.nature.com/neuro/journal/v12/n6/fig_tab/nn.2331_F5.html Reference] (CP.CORTICAL-AUDITORY-SYSTEM) |
− | <img src="http:// | + | AC22=[[BrainRegionNSA_NC_STG_A4|Wernicke's area A4,NSA.NC.STG.A4]] |
+ | Belt42=[[BrainRegionNSA_NC_TTG_A2|Auditory Association Area,NSA.NC.TTG.A2]] | ||
+ | Core41=[[BrainRegionNSA_NC_TTG_A1|Primary Auditory Cortex,NSA.NC.TTG.A1]] | ||
+ | IFC44=Broca's Area,NPE.NC.PFC.BRA (see [[BrainCenterNC_AL_LPFC|Lateral Prefrontal Cortex]]) | ||
+ | IFC45=Broca's Area,NPE.NC.PFC.BRA (see [[BrainCenterNC_AL_LPFC|Lateral Prefrontal Cortex]]) | ||
+ | IPL40=Supramarginal Gyrus,NC.IPL.SMG (see [[BrainCenterNC_IPL|Inferior Parietal Lobule]]) | ||
+ | PMC6=Ventral Premotor Cortex,MCA.NC.VPMC (see [[BrainCenterNC_PMC|Premotor Cortex]]) | ||
+ | PMC8=[[BrainRegionNPE_NC_PMC_AFEF|Anterior Frontal Eye Field,NPE.NC.PMC.AFEF]] | ||
+ | STS22=[[BrainRegionNSA_NC_STG_A3|Wernicke's area A3,NSA.NC.STG.A3]] | ||
+ | <img src="http://ahuman.org/svn/ahwiki/images/ext/93dc9c466b42f33ebd6a47d33a42313f.jpg" alt=alt="unavailable" style="max-width: 100%;"> | ||
− | * [http://www.neurology.org/content/70/21/1991/F2.large.jpg Functional subdivisions of the subthalamic nucleus] - see [http://www.neurology.org/content/70/21/1991/F2.expansion.html Reference] | + | * [http://www.neurology.org/content/70/21/1991/F2.large.jpg Functional subdivisions of the subthalamic nucleus] - see [http://www.neurology.org/content/70/21/1991/F2.expansion.html Reference] (CM.STN-CONN) |
− | <img src="http:// | + | ACG=Anterior Cingulate Cortex,NC.AL.ACG (see [[BrainCenterNC_ACG|Anterior Cingulate Area]]) |
+ | FEF=Frontal Eye Field,NMA.NC.PMC.FEF (see [[BrainCenterNC_PMC|Premotor Cortex]]) | ||
+ | GPe=Globus Pallidus External,FEC.FT.GPE (see [[BrainCenterFEC_FT_BG|Basal Ganglia]]) | ||
+ | GPi=Globus Pallidus Internal,FEC.FT.GPI (see [[BrainCenterFEC_FT_BG|Basal Ganglia]]) | ||
+ | MC=[[BrainRegionNMA_NC_MC|Motor Cortex,NMA.NC.MC]] | ||
+ | SNr=Substantia Nigra Pars Reticulata,FEC.FT.SNR (see [[BrainCenterFEC_FT_BG|Basal Ganglia]]) | ||
+ | STN=Subthalamic Nucleus,FEC.FD.STN (see [[BrainCenterFEC_FD_STA|Subthalamus Area]]) | ||
+ | VP=Ventral Pallidum,FEC.FT.VP (see [[BrainCenterFEC_FT_BG|Basal Ganglia]]) | ||
+ | <img src="http://ahuman.org/svn/ahwiki/images/ext/ced8710309da7474ec475785e9cc3d0a.jpg" alt=alt="unavailable" style="max-width: 100%;"> | ||
− | * [http://dev.epubbud.com/uploads/9/2/6/9263981/images/Medical_Physiology_A_Systems_Approach__1e_2011_pdf/index-187_1.jpg Motor neurons control] - see [http://openagrosrl.com/www/page/292/ Reference] | + | * [http://dev.epubbud.com/uploads/9/2/6/9263981/images/Medical_Physiology_A_Systems_Approach__1e_2011_pdf/index-187_1.jpg Motor neurons control] - see [http://openagrosrl.com/www/page/292/ Reference] (CM.CR-MN) |
− | <img src="http:// | + | CR=Cerebellum,LLC.HT.CR (see [[BrainCenterLLC_HT_CRC|Cerebellar Complex]]) |
+ | CTX=Anterior Lobe,NC.LOBE.ANT | ||
+ | EAMN=[[BrainCenterSC_VH|Anterior/Ventral Horn,SC.VH]] | ||
+ | EGMN=[[BrainCenterSC_VH|Anterior/Ventral Horn,SC.VH]] | ||
+ | FAMN=[[BrainCenterSC_VH|Anterior/Ventral Horn,SC.VH]] | ||
+ | FG=[[BrainRegionLRC_HT_CR_FG|Fastigual Nucleus,LRC.HT.CR.FG]] | ||
+ | IP=Interposed Nucleus,LLC.HT.CR.IP (see [[BrainCenterLLC_HT_CRC|Cerebellar Complex]]) | ||
+ | LT=[[BrainRegionLLC_HT_CR_DN|Dentate Nucleus,LLC.HT.CR.DN]] | ||
+ | MRF=[[BrainCenterHL_RF|Medullary Reticular Formation,HL.RF]] | ||
+ | PRF=[[BrainCenterHT_RF|Pontine Reticular Formation,HT.RF]] | ||
+ | RD=[[BrainCenterLLC_MM_RD|Red Nucleus,LLC.MM.RD]] | ||
+ | VB=[[BrainCenterLPC_HT_VBN|Vestibular Nuclei,LPC.HT.VBN]] | ||
+ | <img src="http://ahuman.org/svn/ahwiki/images/ext/2c4f43876377580a8d7d56c656b782f4.jpg" alt=alt="unavailable" style="max-width: 100%;"> | ||
− | * [http://ars.els-cdn.com/content/image/1-s2.0-S1053810011000080-gr3.jpg Cortico-Cortical Connectivity] - see [http://www.sciencedirect.com/science/article/pii/S1053810011000080 Reference] | + | * [http://ars.els-cdn.com/content/image/1-s2.0-S1053810011000080-gr3.jpg Cortico-Cortical Connectivity] - see [http://www.sciencedirect.com/science/article/pii/S1053810011000080 Reference] (CL.CORTICO-CORTICAL-CONNECTIVITY) |
− | <img src="http:// | + | A1=[[BrainRegionNSA_NC_TTG_A1|Primary Auditory Cortex,NSA.NC.TTG.A1]] |
+ | AA=[[BrainRegionNSA_NC_STG_A3|Wernicke's area A3,NSA.NC.STG.A3]] | ||
+ | M1=[[BrainRegionNMA_NC_MC|Motor Cortex,NMA.NC.MC]] | ||
+ | MA=[[BrainCenterNC_PMC|Premotor Cortex,NC.PMC]] | ||
+ | PFC=Prefrontal Cortex,NC.AL.PFC | ||
+ | PTHA=[[BrainCenterNC_IPL|Inferior Parietal Lobule,NC.IPL]] | ||
+ | S1=[[BrainRegionNCP_NC_PG_S1|Primary Somatosensory Cortex,NCP.NC.PG.S1]] | ||
+ | SA=[[BrainRegionNCP_NC_SPL_SA|Somatosensory Association Cortex,NCP.NC.SPL.SA]] | ||
+ | V1=[[BrainRegionNSA_NC_OCC_V1|Primary Visual Cortex,NSA.NC.OCC.V1]] | ||
+ | VA=Secondary Visual Cortex,NSA.NC.OCC.V2 (see [[BrainCenterNC_LOBE_OCC|Occipital Lobe]]) | ||
+ | <img src="http://ahuman.org/svn/ahwiki/images/ext/df75e61c2e90c60db0f2204bcedbc309.jpg" alt=alt="unavailable" style="max-width: 100%;"> | ||
Latest revision as of 18:33, 28 April 2019
Anterior Frontal Eye Field
@@Home -> BiologicalLifeResearch -> BrainAreaNPE -> BrainRegionNPE_NC_PMC_AFEF
This page covers biological details of component Anterior Frontal Eye Field. Region is part of aHuman target integrated biological model.
- Top-down path to region: Cerebral Cortex -> Anterior Lobe (NC.LOBE.ANT) -> Premotor Cortex (NC.PMC) -> Frontal Eye Field (NMA.NC.PMC.FEF) -> Anterior Frontal Eye Field (NPE.NC.PMC.AFEF) (see Mind Maps)
- Type: cortex
- Quality: L0
- Brain area: Neocortical Brain - Unimodal Execution Area (NPE)
- Area circuit: Cortical Vision Control (CVC)
- Brodmann ID: 08
- Role: cortex.generic
- Function: Head and eye movements toward auditory stimuli
- Notes to function:
- longer saccades, dorsomedial - 8A (8Ac, 8Am), but not 8Ar
- 8Ac - saccades
(generated)
Components
(generated)
- no child items defined
Connectivity
(generated)
Inbound Region Connections:
Source Area | Source Region | Source Name | Type | Role | Reference |
NDM | NDM.NC.AL.DLPFCL | Lateral Mid-Dorsolateral Prefrontal Cortex | feedforward-glu | uncertain | Prefrontal Cortex (PFC) in motor behavior (LPFC -> PMC, abstract) |
NMA | NMA.FD.TH.MDL | Lateral Mediodorsal Nucleus of Thalamus | excitatory-glu | uncertain | Oculomotor decision-making (Thalamus -> FEF, abstract) |
NPE | NPE.NC.BRA.PO | Broca's Area Pars Opercularis | feedforward-glu | uncertain | Cortical Auditory System (IFC44 -> PMC8, abstract) |
NPE.NC.PMC.CFEF | Caudal Frontal Eye Field | feedforward-glu | uncertain | (unknown reference) | |
NPE.NC.SMC.SEF | Supplementary Eye Field | feedforward-glu | uncertain | Summary of eye movement control (SEF -> FEF, abstract) |
Outbound Region Connections:
Target Area | Target Region | Target Name | Type | Role | Reference |
FEC | FEC.FD.STN.MED | Subthalamic Nucleus Medial | excitatory-glu | uncertain | Functional subdivisions of the subthalamic nucleus (FEF -> STN, abstract) |
FEC.FT.CN.BD | Caudate Nucleus Body | excitatory-glu | uncertain | Global visual system (FrontalCortex -> BGA, abstract) | |
LRC | LRC.HL.PRF.GCR | Gigantocellular Reticular Nucleus | excitatory-glu | uncertain | Motor neurons control (CTX -> MRF, abstract) |
LRC.HT.PRF.RPO | Oral Pontine Reticular Nucleus | excitatory-glu | uncertain | Motor neurons control (CTX -> PRF, abstract) | |
LRC.MM.CJ | Cajal Nucleus | excitatory-glu | uncertain | Summary of eye movement control (FEF -> riMLF, abstract) | |
LRC.MM.DSCH | Darkschewitsch Nucleus | excitatory-glu | uncertain | (unknown reference) | |
LRC.MM.SC.INT | Intermediate Superior Colliculus | excitatory-glu | uncertain | Summary of eye movement control (FEF -> SC, abstract) | |
NMA | NMA.NC.PMC.F5 | Ventral Rostral Premotor Cortex | feedforward-glu | uncertain | Cortical Auditory System (PMC8 -> PMC6, abstract) |
NMA.NC.PMC.F7 | Dorsal Rostral Premotor Cortex | feedforward-glu | uncertain | (unknown reference) |
Thirdparty Circuits
(generated)
- Global visual system - see Reference (CP.GLOBAL-VISUAL-SYSTEM)
ATH=Anterior Nucleus of Thalamus,FD.TH.AN (see Cognitive Thalamus) BGA=Basal Ganglia,FEC.FT.BG FrontalCortex=Anterior Lobe,NC.LOBE.ANT LGN=Lateral Geniculate Nucleus,NSA.FD.LGN OPN=Oculomotor Nucleus,LPC.MM.OCN ParietalCortex=Parietal Lobe,NC.LOBE.PAR Pulvinar=Pulvinar,FD.PV (see Sensory Thalamus) RF=Pontine Reticular Formation,HT.RF Retina=Retinal Nucleus,LPC.FD.RT SCi=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon) SCs=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon) SNc=Substantia Nigra Pars Compacta Lateral,FEC.FT.SNC.LT SNr=Substantia Nigra Pars Reticulata Dorsolateral,FEC.FT.SNR.DL SpinalCord=Lamina IX,SC.VH.L9 (see Anterior/Ventral Horn) Striatum=Striatum,FEC.FT.ST (see Basal Ganglia) VisualCortex=Occipital Lobe,NC.LOBE.OCC
- Summary of eye movement control - see Reference (CP.EYE-FIELDS)
DLPFC=Mid-Dorsolateral Prefrontal Cortex,NDM.NC.AL.DLPFC (see Lateral Prefrontal Cortex) FEF=Frontal Eye Field,NMA.NC.PMC.FEF (see Premotor Cortex) PEF=Posterior Eye Field,NPE.NC.IPS.PEF (see Intraparietal Sulcus) PPRF=Paramedian Pontine Reticular Formation,HT.PRF.PPRF (see Pontine Reticular Formation) SC=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon) SEF=Supplementary Eye Field,NPE.NC.SMC.SEF riMLF=Cajal Nucleus,LRC.MM.CJ
- Cortical Auditory System - see Reference (CP.CORTICAL-AUDITORY-SYSTEM)
AC22=Wernicke's area A4,NSA.NC.STG.A4 Belt42=Auditory Association Area,NSA.NC.TTG.A2 Core41=Primary Auditory Cortex,NSA.NC.TTG.A1 IFC44=Broca's Area,NPE.NC.PFC.BRA (see Lateral Prefrontal Cortex) IFC45=Broca's Area,NPE.NC.PFC.BRA (see Lateral Prefrontal Cortex) IPL40=Supramarginal Gyrus,NC.IPL.SMG (see Inferior Parietal Lobule) PMC6=Ventral Premotor Cortex,MCA.NC.VPMC (see Premotor Cortex) PMC8=Anterior Frontal Eye Field,NPE.NC.PMC.AFEF STS22=Wernicke's area A3,NSA.NC.STG.A3
- Functional subdivisions of the subthalamic nucleus - see Reference (CM.STN-CONN)
ACG=Anterior Cingulate Cortex,NC.AL.ACG (see Anterior Cingulate Area) FEF=Frontal Eye Field,NMA.NC.PMC.FEF (see Premotor Cortex) GPe=Globus Pallidus External,FEC.FT.GPE (see Basal Ganglia) GPi=Globus Pallidus Internal,FEC.FT.GPI (see Basal Ganglia) MC=Motor Cortex,NMA.NC.MC SNr=Substantia Nigra Pars Reticulata,FEC.FT.SNR (see Basal Ganglia) STN=Subthalamic Nucleus,FEC.FD.STN (see Subthalamus Area) VP=Ventral Pallidum,FEC.FT.VP (see Basal Ganglia)
- Motor neurons control - see Reference (CM.CR-MN)
CR=Cerebellum,LLC.HT.CR (see Cerebellar Complex) CTX=Anterior Lobe,NC.LOBE.ANT EAMN=Anterior/Ventral Horn,SC.VH EGMN=Anterior/Ventral Horn,SC.VH FAMN=Anterior/Ventral Horn,SC.VH FG=Fastigual Nucleus,LRC.HT.CR.FG IP=Interposed Nucleus,LLC.HT.CR.IP (see Cerebellar Complex) LT=Dentate Nucleus,LLC.HT.CR.DN MRF=Medullary Reticular Formation,HL.RF PRF=Pontine Reticular Formation,HT.RF RD=Red Nucleus,LLC.MM.RD VB=Vestibular Nuclei,LPC.HT.VBN
- Cortico-Cortical Connectivity - see Reference (CL.CORTICO-CORTICAL-CONNECTIVITY)
A1=Primary Auditory Cortex,NSA.NC.TTG.A1 AA=Wernicke's area A3,NSA.NC.STG.A3 M1=Motor Cortex,NMA.NC.MC MA=Premotor Cortex,NC.PMC PFC=Prefrontal Cortex,NC.AL.PFC PTHA=Inferior Parietal Lobule,NC.IPL S1=Primary Somatosensory Cortex,NCP.NC.PG.S1 SA=Somatosensory Association Cortex,NCP.NC.SPL.SA V1=Primary Visual Cortex,NSA.NC.OCC.V1 VA=Secondary Visual Cortex,NSA.NC.OCC.V2 (see Occipital Lobe)
References
(generated)
- http://www.sciencedirect.com/science/article/pii/S0959438808001566
- http://www.cixip.com/index.php/page/content/id/1190
- http://www.nature.com/neuro/journal/v12/n6/fig_tab/nn.2331_F5.html
- http://www.neurology.org/content/70/21/1991/F2.expansion.html
- http://openagrosrl.com/www/page/292/
- http://www.sciencedirect.com/science/article/pii/S1053810011000080