BrainRegionLRC HT PRF RPO
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Oral Pontine Reticular Nucleus
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This page covers biological details of component Oral Pontine Reticular Nucleus. Region is part of aHuman target integrated biological model.
- Top-down path to region: Hindbrain Metencephalon -> Pontine Reticular Formation (HT.RF) -> Pontine Reticular Formation, Medial Column (HT.RF.MED) -> Paramedian Pontine Reticular Formation (HT.PRF.PPRF) -> Oral Pontine Reticular Nucleus (LRC.HT.PRF.RPO) (see Mind Maps)
- Type: nucleus
- Quality: L0
- Brain area: Lower Brain - Motor Reflex Area (LRC)
- Area circuit: Postural Control Reflexes (LRP)
- Role: subcortical.motor.flexor
- Function: Mediation of changing to and from REM sleep
- Notes to function:
- Part of horizontal gaze center, projects to spinal cord and abducens
- excites spinal extensors, inhibit flexors
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Components
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- no child items defined
Connectivity
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Inbound Region Connections:
| Source Area | Source Region | Source Name | Type | Role | Reference |
| LRC | LRC.MM.RP.RIP | Raphe Interpositus Nucleus | excitatory-glu | uncertain | Horizontal saccades and smooth pursuit movements (RIP -> PPRF, abstract) |
| LRC.MM.SC.DEEP | Deep Superior Colliculus | excitatory-glu | uncertain | Summary of eye movement control (SC -> PPRF, abstract) | |
| NPE | NPE.NC.BRA.PO | Broca's Area Pars Opercularis | excitatory-glu | uncertain | Motor neurons control (CTX -> PRF, abstract) |
| NPE.NC.PMC.AFEF | Anterior Frontal Eye Field | excitatory-glu | uncertain | Motor neurons control (CTX -> PRF, abstract) | |
| NSA | NSA.NC.IT.TE | Inferotemporal Cortex | excitatory-glu | uncertain | Saccades and smooth movements (TEF -> DLPN, abstract) |
Outbound Region Connections:
| Target Area | Target Region | Target Name | Type | Role | Reference |
| FAM | FAM.HT.TG.NI | Incertus Nucleus | excitatory-glu | uncertain | (unknown reference) |
| LLC | LLC.HT.CR.CC | Cerebellar Lateral Lobe | excitatory-glu | uncertain | Saccades and smooth movements (DLPN -> CR, abstract) |
| LPC | LPC.HT.ABD | Abducens Nucleus | excitatory-glu | uncertain | Vestibulo-ocular reflex (VOR) (PPRF -> Abducens, abstract) |
| LPC.HT.IVBN | Inferior Vestibular Nuclei | excitatory-glu | uncertain | (unknown reference) | |
| LPC.MM.OCN | Oculomotor Nucleus | excitatory-glu | uncertain | Global visual system (RF -> OPN, abstract) | |
| LPC.SC.VH.SAN | Spinal Accessory Nucleus | excitatory-glu | uncertain | Cerebellum functional divisions (RF -> SCM, abstract) | |
| LPC.SC.VH.VL | Ventrolateral Nucleus | excitatory-glu | uncertain | Cerebellum functional divisions (RF -> SCM, abstract) | |
| LPC.SC.VH.VM | Ventromedial Nucleus | excitatory-glu | uncertain | Cerebellum functional divisions (RF -> SCM, abstract) |
Thirdparty Circuits
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- Vestibulo-ocular reflex (VOR) - see Reference (CP.VESTIBULO-OCULAR-REFLEX)
Abducens=Abducens Nucleus,LPC.HT.ABD FEF=Frontal Eye Field,NMA.NC.PMC.FEF (see Premotor Cortex) Oculomotor=Oculomotor Nucleus,LPC.MM.OCN PPRF=Paramedian Pontine Reticular Formation,HT.PRF.PPRF (see Pontine Reticular Formation) VestibularGanglion=Vestibular Ganglion,LPC.PN.SG.VB VestibularNuclei=Inferior Vestibular Nuclei,LPC.HT.IVBN
- Saccades and smooth movements (unknown reference) (CP.SACCADIC-VOLUNTARY-AND-PURSUIT)
CN=Caudate Nucleus,FEC.FT.CN (see Basal Ganglia) CR=Cerebellum,LLC.HT.CR (see Cerebellar Complex) DLPN=Oral Pontine Reticular Nucleus,LRC.HT.PRF.RPO Extrastriate=Associative Visual Cortex,NPE.NC.OCC.V3 (see Occipital Lobe) FEF=Frontal Eye Field,NMA.NC.PMC.FEF (see Premotor Cortex) PPC=Posterior Eye Field,NPE.NC.IPS.PEF (see Intraparietal Sulcus) PPRF=Paramedian Pontine Reticular Formation,HT.PRF.PPRF (see Pontine Reticular Formation) SC=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon) SN=Substantia Nigra,FEC.FT.SN (see Basal Ganglia) Striate=Primary Visual Cortex,NSA.NC.OCC.V1 TEF=Inferotemporal Area,NSA.NC.IT VGC=Cajal Nucleus,LRC.MM.CJ Vestibular=Lateral Vestibular Nucleus,LPC.HT.LVBN
- Global visual system - see Reference (CP.GLOBAL-VISUAL-SYSTEM)
ATH=Anterior Nucleus of Thalamus,FD.TH.AN (see Cognitive Thalamus) BGA=Basal Ganglia,FEC.FT.BG FrontalCortex=Anterior Lobe,NC.LOBE.ANT LGN=Lateral Geniculate Nucleus,NSA.FD.LGN OPN=Oculomotor Nucleus,LPC.MM.OCN ParietalCortex=Parietal Lobe,NC.LOBE.PAR Pulvinar=Pulvinar,FD.PV (see Sensory Thalamus) RF=Pontine Reticular Formation,HT.RF Retina=Retinal Nucleus,LPC.FD.RT SCi=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon) SCs=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon) SNc=Substantia Nigra Pars Compacta Lateral,FEC.FT.SNC.LT SNr=Substantia Nigra Pars Reticulata Dorsolateral,FEC.FT.SNR.DL SpinalCord=Lamina IX,SC.VH.L9 (see Anterior/Ventral Horn) Striatum=Striatum,FEC.FT.ST (see Basal Ganglia) VisualCortex=Occipital Lobe,NC.LOBE.OCC
- Cerebellum functional divisions - see Reference (CM.CR-DECUSSATION)
CCV=Central Cervical Nucleus,LPC.SC.IZ.CCV CRP=Cerebellar Lateral Lobe,LLC.HT.CR.CC CRS=Cerebellar Paravermis,LLC.HT.CR.PV CRV=Cerebellar Vermis,LRC.HT.CR.VM CTX=Anterior Lobe,NC.LOBE.ANT DN=Dentate Nucleus,LLC.HT.CR.DN FG=Fastigual Nucleus,LRC.HT.CR.FG IO=Inferior Olivary Nucleus,LLC.HL.IO IP=Interposed Nucleus,LLC.HT.CR.IP (see Cerebellar Complex) LT=Dentate Nucleus,LLC.HT.CR.DN PNN=Basilar Pontine Nuclei,LLC.HT.BPN RD=Red Nucleus,LLC.MM.RD RF=Pontine Reticular Formation,HT.RF SCM=Anterior/Ventral Horn,SC.VH SCS=Proprius Nucleus,LPC.SC.PH.NP SCSD=Clarke Nucleus,LPC.SC.PH.CL VB=Vestibular Nuclei,LPC.HT.VBN VBG=Vestibular Ganglion,LPC.PN.SG.VB VL=Ventral Lateral Nucleus,NMA.FD.TH.VL
References
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