BrainRegionFEC FT ACC SH

Nucleus Accumbens Shell

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This page covers biological details of component Nucleus Accumbens Shell. Region is part of aHuman target integrated biological model.

• Top-down path to region: Forebrain Telencephalon -> Basal Ganglia (BGA.FT.BG) -> Striatum (BGA.FT.ST) -> Ventral Striatum (BGA.FT.VST) -> Accumbens Nucleus (FEC.FT.ACC) -> Nucleus Accumbens Shell (FEC.FT.ACC.SH) (see Mind Maps)
• Type: nucleus
• Brain area: Forebrain - Execution Control Area
• Role: relay
• Function: cognitive processing of motivational salience (wanting) as well as reward and reinforcement effects

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Components

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Connectivity

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Inbound Region Connections:

Source Area	Source Region	Source Name	Type	Reference
FEC	FEC.FT.SNC.MED	Substantia Nigra Pars Compacta Medial	modulatory-da	(unknown reference)
LMC	LMC.MM.VTA	Ventral Tegmental Area	modulatory-da	Craving (VTA -> NACC, abstract)
NCP	NCP.NC.MPL.PSCG	Posterior Cingulate Cortex	excitatory-glu	(unknown reference)
NDM	NDM.NC.AL.VACG	Ventral Anterior Cingulate Area	excitatory-glu	Global visual system (FrontalCortex -> BGA, abstract)

Outbound Region Connections:

Target Area	Target Region	Target Name	Type	Reference
FEC	FEC.FT.IPAC.LT	Lateral Interstitial Anterior Commissural Nucleus	inhibitory-gaba	(unknown reference)
	FEC.FT.VP.VM	Ventral Pallidum Ventromedial	inhibitory-gaba	Craving (NACC -> VPAL, abstract)
LAC	LAC.FD.HT.LTN	Lateral Hypothalamic Nucleus	inhibitory-gaba	(unknown reference)
LMC	LMC.FT.NBM	Basal Nucleus of Meynert	inhibitory-gaba	Affective basal ganglia circuit (NACC -> nBM, abstract)

Thirdparty Circuits

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References

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