BrainRegionNDM NC AL ROFCR
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Most Rostral Orbitofrontal Cortex
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This page covers biological details of component Most Rostral Orbitofrontal Cortex. Region is part of aHuman target integrated biological model.
- Top-down path to region: Cerebral Cortex -> Anterior Lobe (NC.LOBE.ANT) -> Prefrontal Cortex (NC.AL.PFC) -> Orbitomedial Prefrontal Cortex (NC.AL.OMPFC) -> Orbitofrontal Cortex (NC.AL.OPFC) -> Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFC) -> Most Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCR) (see Mind Maps)
- Type: cortex
- Quality: L0
- Brain area: Neocortical Brain - Decision Making Area (NDM)
- Area circuit: High-Level Novelty Attention (HLNM)
- Brodmann ID: 12
- Role: cortex.generic
- Function: Integral conscious selection of novelty
- Notes to function:
- 12R
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Components
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- no child items defined
Connectivity
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Inbound Region Connections:
| Source Area | Source Region | Source Name | Type | Role | Reference |
| FAM | FAM.FD.TH.PT | Paratenial Nucleus of Thalamus | excitatory-glu | uncertain | Saccadic Vision (Thalamus -> FrontalCortex, abstract) |
| FMM | FMM.FT.HC.CA1D | Distal CA1 of Hippocampus | excitatory-glu | uncertain | Simplified model of hippocampal formation anatomy (CA1 -> mPFC, abstract) |
| FMM.FT.HF.SUBD | Distal Subiculum | excitatory-glu | uncertain | Simplified model of hippocampal formation anatomy (SUB -> mPFC, abstract) | |
| NCP | NCP.NC.MPL.RSC | Retrosplenial Cortex | feedforward-glu | uncertain | Prefrontal Cortex (PFC) in emotional behavior (PCA -> OPFC, abstract) |
| NDM | NDM.NC.AL.ROFCL | Lateral Rostral Orbitofrontal Cortex | feedforward-glu | uncertain | Regulation of Social Brain (MPFC -> OFC, abstract) |
| NDM.NC.AL.ROFCM | Medial Rostral Orbitofrontal Cortex | feedforward-glu | uncertain | Regulation of Social Brain (MPFC -> OFC, abstract) |
Outbound Region Connections:
| Target Area | Target Region | Target Name | Type | Role | Reference |
| FEC | FEC.FD.STN.DL | Subthalamic Nucleus Dorsolateral | excitatory-glu | uncertain | Serotonin regulation of subthalamic neurons (CTX -> STN, abstract) |
| FEC.FT.CN.TL | Caudate Nucleus Tail | excitatory-glu | uncertain | Global visual system (FrontalCortex -> BGA, abstract) | |
| FMM | FMM.FD.TH.RE | Reuniens Nucleus of Thalamus | excitatory-glu | uncertain | (unknown reference) |
| FMM.FD.TH.RH | Rhomboidal Nucleus of Thalamus | excitatory-glu | uncertain | (unknown reference) | |
| NDM | NDM.NC.AL.DACG | Dorsal Anterior Cingulate Area | feedforward-glu | uncertain | Role for serotonin in moral behavior (OMPFC -> ACG, abstract) |
| NDM.NC.AL.IPG | Inferior Prefrontal Gyrus | feedforward-glu | uncertain | Regulation of Social Brain (OFC -> IFG, abstract) |
Thirdparty Circuits
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- Regulation of Social Brain - see Reference (CT.SOCIAL-BRAIN)
AMG=Amygdala,FAM.FT.AM Caud=Caudate Nucleus,FEC.FT.CN (see Basal Ganglia) DACC=Dorsal Anterior Cingulate Area,NDM.NC.AL.DACG DLPFC=Mid-Dorsolateral Prefrontal Cortex,NDM.NC.AL.DLPFC (see Lateral Prefrontal Cortex) Hipp=Hippocampus,FMM.FT.HC (see Hippocampal Formation) IFG=Inferior Prefrontal Gyrus,NDM.NC.AL.IPG LSN=Lateral Spinal Nucleus,LAC.SC.LH.LSN MPFC=Orbitofrontal Cortex,NC.AL.OPFC (see Orbitomedial Prefrontal Cortex) NACC=Accumbens Nucleus,FEC.FT.ACC (see Basal Ganglia) OFC=Orbitofrontal Cortex,NC.AL.OPFC (see Orbitomedial Prefrontal Cortex) PhippG=Entorhinal Cortex,FMM.NC.PH.ET (see Rhinal Cortex) Put=Dorsal Putamen,FEC.FT.DPU (see Basal Ganglia) SGC=Subgenual Cingulate Cortex,NCP.NC.AL.SGCG SN=Substantia Nigra,FEC.FT.SN (see Basal Ganglia) VACC=Ventral Anterior Cingulate Area,NDM.NC.AL.VACG VTA=Ventral Tegmental Area,LMC.MM.VTA VentPal=Ventral Pallidum,FEC.FT.VP (see Basal Ganglia)
- Global visual system - see Reference (CP.GLOBAL-VISUAL-SYSTEM)
ATH=Anterior Nucleus of Thalamus,FD.TH.AN (see Cognitive Thalamus) BGA=Basal Ganglia,FEC.FT.BG FrontalCortex=Anterior Lobe,NC.LOBE.ANT LGN=Lateral Geniculate Nucleus,NSA.FD.LGN OPN=Oculomotor Nucleus,LPC.MM.OCN ParietalCortex=Parietal Lobe,NC.LOBE.PAR Pulvinar=Pulvinar,FD.PV (see Sensory Thalamus) RF=Pontine Reticular Formation,HT.RF Retina=Retinal Nucleus,LPC.FD.RT SCi=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon) SCs=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon) SNc=Substantia Nigra Pars Compacta Lateral,FEC.FT.SNC.LT SNr=Substantia Nigra Pars Reticulata Dorsolateral,FEC.FT.SNR.DL SpinalCord=Lamina IX,SC.VH.L9 (see Anterior/Ventral Horn) Striatum=Striatum,FEC.FT.ST (see Basal Ganglia) VisualCortex=Occipital Lobe,NC.LOBE.OCC
- Serotonin regulation of subthalamic neurons - see Reference (CM.SUBTHALAMUS)
CTX=Anterior Lobe,NC.LOBE.ANT GPe=Globus Pallidus External,FEC.FT.GPE (see Basal Ganglia) GPi=Globus Pallidus Internal,FEC.FT.GPI (see Basal Ganglia) PPN=Pedunculopontine Tegmental Nuclei,LMC.HT.TG.PPN SNr=Substantia Nigra Pars Reticulata,FEC.FT.SNR (see Basal Ganglia) STN=Subthalamic Nucleus,FEC.FD.STN (see Subthalamus Area)
- Role for serotonin in moral behavior - see Reference (CF.EMOTIONAL-MODULATION)
ACG=Anterior Cingulate Cortex,NC.AL.ACG (see Anterior Cingulate Area) AMY=Amygdala,FAM.FT.AM HYP=Hypothalamus,FD.HT LPFC=Mid-Dorsolateral Prefrontal Cortex,NDM.NC.AL.DLPFC (see Lateral Prefrontal Cortex) OMPFC=Orbitofrontal Cortex,NC.AL.OPFC (see Orbitomedial Prefrontal Cortex)
References
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