BrainRegionLAC FD HT AR
Arcuate Nucleus of Hypothalamus
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This page covers biological details of component Arcuate Nucleus of Hypothalamus. Region is part of aHuman target integrated biological model.
- Top-down path to region: Forebrain Diencephalon -> Hypothalamus (FD.HT) -> Anterior Hypothalamus Area (LAC.FD.HT.AHT) -> Tuberal Area (LAC.FD.HT.TUB) -> Arcuate Nucleus of Hypothalamus (LAC.FD.HT.AR) (see Mind Maps)
- Type: nucleus
- Brain area: Lower Brain - Autonomous Control Area
- Role: processor.autonomic
- Function: Regulation of growth, appetite and body weight
- Notes to function: lateral of tuberlulum, TIDA - releases dopamine to regulate secretion of prolactin hormone, GHRH - stimulate growth hormone secretion (ventrolateral)
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Components
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- no child items defined
Connectivity
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Inbound Region Connections:
- no connections
Outbound Region Connections:
| Target Area | Target Region | Target Name | Type | Reference |
| LAC | LAC.FD.HT.DM | Dorsomedial Hypothalamic Nucleus | excitatory-glu | Intrahypothalamic connections important for neural control of food intake and energy balance (ARC -> DMN) |
| LAC.FD.HT.LTN | Lateral Hypothalamic Nucleus | excitatory-glu | Intrahypothalamic connections important for neural control of food intake and energy balance (ARC -> LHA) | |
| LAC.FD.HT.PV | Paraventricular Nucleus | excitatory-glu | Intrahypothalamic connections important for neural control of food intake and energy balance (ARC -> PA) | |
| LAC.FD.HT.VM | Ventromedial Hypothalamic Nucleus | excitatory-glu | Schematic of hypothalamic circuitry underlying satiety (ARC -> VMH) | |
| TEA | TARGET.TEA.ENDOCRINE | Endocrine Glands | endocrine-adenohypophysis | (unknown reference) |
Thirdparty Circuits
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- Intrahypothalamic connections important for neural control of food intake and energy balance - see Reference
map: AH=Anterior Hypothalamic Nucleus,LAC.FD.HT.AH, ARC=Arcuate Nucleus of Hypothalamus,LAC.FD.HT.AR, DMN=Dorsomedial Hypothalamic Nucleus,LAC.FD.HT.DM, LHA=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN, MPOA=Median Preoptic Nucleus,LAC.FD.HT.MPO, PA=Paraventricular Nucleus,LAC.FD.HT.PV, SCH=Suprachiasmatic Nucleus,LAC.FD.HT.SCN, SON=Supraoptic Nucleus,LAC.FD.HT.SO, VMN=Ventromedial Hypothalamic Nucleus,LAC.FD.HT.VM
map: ARC=Arcuate Nucleus of Hypothalamus,LAC.FD.HT.AR, DMH=Dorsomedial Hypothalamic Nucleus,LAC.FD.HT.DM, LHA=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN, NTS=Solitary Nucleus,LPC.HL.SOL, PVN=Paraventricular Nucleus,LAC.FD.HT.PV, VMH=Ventromedial Hypothalamic Nucleus,LAC.FD.HT.VM
map: ARC=Arcuate Nucleus of Hypothalamus,LAC.FD.HT.AR, DMN=Dorsomedial Hypothalamic Nucleus,LAC.FD.HT.DM, LHA=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN, PVH=Paraventricular Nucleus,LAC.FD.HT.PV, VMH=Ventromedial Hypothalamic Nucleus,LAC.FD.HT.VM
map: ARC=Arcuate Nucleus of Hypothalamus,LAC.FD.HT.AR, DMH=Dorsomedial Hypothalamic Nucleus,LAC.FD.HT.DM, LHA=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN, MPO=Median Preoptic Nucleus,LAC.FD.HT.MPO, PVH=Paraventricular Nucleus,LAC.FD.HT.PV, SCN=Suprachiasmatic Nucleus,LAC.FD.HT.SCN, VLPO=Ventrolateral Preoptic Nucleus,LAC.FD.HT.VLPO, VMH=Ventromedial Hypothalamic Nucleus,LAC.FD.HT.VM
map: AMY=Amygdala,FAM.FT.AM, ARC=Arcuate Nucleus of Hypothalamus,LAC.FD.HT.AR, DS=Dorsal Striatum,FEC.FT.DST (Caudate Nucleus Head (FEC.FT.CN.HD), Caudate Nucleus Body (FEC.FT.CN.BD), Caudate Nucleus Tail (FEC.FT.CN.TL), Dorsal Putamen Lateral (FEC.FT.PU.LT), Dorsal Putamen Medial (FEC.FT.PU.MED)), LHA=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN, ME=Endocrine Glands,TARGET.TEA.ENDOCRINE, NAc=Accumbens Nucleus,FEC.FT.ACC (Nucleus Accumbens Core (FEC.FT.ACC.CORE), Nucleus Accumbens Shell (FEC.FT.ACC.SH)), NTS=Solitary Nucleus,LPC.HL.SOL, OFC=Orbitofrontal Cortex,NC.AL.OPFC (Lateral Frontopolar Cortex (NDM.NC.AL.FPC), Most Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCR), Sulcal Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCS), Medial Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCM), Lateral Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCL)), PBN=Parabrachial Nucleus,LPC.HT.PRF.PB, PVN=Paraventricular Nucleus,LAC.FD.HT.PV, VMN=Ventromedial Hypothalamic Nucleus,LAC.FD.HT.VM, VTA=Ventral Tegmental Area,LMC.MM.VTA
References
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- http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.122.2314rep=rep1type=pdf
- http://neuroscience.uth.tmc.edu/s4/chapter04.html
- http://ajpregu.physiology.org/content/302/2/R215
- http://www.dana.org/Publications/ReportDetails.aspx?id=44217
- http://www.nature.com/nrendo/journal/v6/n8/fig_tab/nrendo.2010.93_F1.html
